Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	51144
Gene name Gene Name - the full gene name approved by the HGNC.	Hydroxysteroid 17-beta dehydrogenase 12
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	HSD17B12
Synonyms (NCBI Gene) Gene synonyms aliases	KAR, SDR12C1
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. [provided by RefSeq, Oct 2011]

Show/Hide all(524)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001545	hsa-miR-155-5p	pSILAC	18668040
MIRT001545	hsa-miR-155-5p	Proteomics;Other	18668040
MIRT045813	hsa-miR-191-5p	CLASH	23622248
MIRT037759	hsa-miR-874-3p	CLASH	23622248
MIRT664600	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT664599	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT664597	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT664596	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT664595	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT695784	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT664594	hsa-miR-4252	HITS-CLIP	23313552
MIRT664601	hsa-miR-1273a	HITS-CLIP	23313552
MIRT695783	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT664591	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT664590	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT664589	hsa-miR-7703	HITS-CLIP	23313552
MIRT675510	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT675509	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT649068	hsa-miR-4284	HITS-CLIP	23824327
MIRT675508	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT675507	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT675506	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT675505	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT675504	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT675503	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT675502	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT675501	hsa-miR-7977	HITS-CLIP	23824327
MIRT675500	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT675499	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT675498	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT675497	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT675496	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT675495	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT675494	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT675493	hsa-miR-3689c	HITS-CLIP	23824327
MIRT675492	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT675491	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT675490	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT664602	hsa-miR-6501-3p	HITS-CLIP	23824327
MIRT664601	hsa-miR-1273a	HITS-CLIP	23824327
MIRT664600	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT664599	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT664597	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT664598	hsa-miR-598-5p	HITS-CLIP	23824327
MIRT664596	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT664595	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT664593	hsa-miR-5186	HITS-CLIP	23824327
MIRT664594	hsa-miR-4252	HITS-CLIP	23824327
MIRT664592	hsa-miR-542-3p	HITS-CLIP	23824327
MIRT664591	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT664590	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT664589	hsa-miR-7703	HITS-CLIP	23824327
MIRT664588	hsa-miR-7705	HITS-CLIP	23824327
MIRT664587	hsa-miR-103b	HITS-CLIP	23824327
MIRT664586	hsa-miR-1267	HITS-CLIP	23824327
MIRT664585	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT664584	hsa-miR-4466	HITS-CLIP	23824327
MIRT664583	hsa-miR-675-5p	HITS-CLIP	23824327
MIRT664582	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT664581	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT664580	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT664579	hsa-miR-5698	HITS-CLIP	23824327
MIRT649077	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT649076	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT649075	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT649074	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT649073	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT649072	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT649071	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT649070	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT649069	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT649068	hsa-miR-4284	HITS-CLIP	23824327
MIRT649067	hsa-miR-382-3p	HITS-CLIP	23824327
MIRT649066	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT649065	hsa-miR-548aw	HITS-CLIP	23824327
MIRT649064	hsa-miR-518a-5p	HITS-CLIP	23824327
MIRT649063	hsa-miR-527	HITS-CLIP	23824327
MIRT649062	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT649061	hsa-miR-507	HITS-CLIP	23824327
MIRT649060	hsa-miR-557	HITS-CLIP	23824327
MIRT649059	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT564181	hsa-miR-3163	PAR-CLIP	20371350
MIRT531439	hsa-miR-633	PAR-CLIP	20371350
MIRT531453	hsa-miR-4280	PAR-CLIP	22012620
MIRT531452	hsa-miR-205-3p	PAR-CLIP	22012620
MIRT531451	hsa-miR-936	PAR-CLIP	22012620
MIRT531450	hsa-miR-199a-3p	PAR-CLIP	22012620
MIRT531449	hsa-miR-199b-3p	PAR-CLIP	22012620
MIRT531448	hsa-miR-3129-5p	PAR-CLIP	22012620
MIRT531447	hsa-miR-29a-5p	PAR-CLIP	22012620
MIRT531446	hsa-miR-494-3p	PAR-CLIP	22012620
MIRT531445	hsa-miR-142-3p	PAR-CLIP	22012620
MIRT531444	hsa-miR-222-5p	PAR-CLIP	22012620
MIRT531443	hsa-miR-510-3p	PAR-CLIP	22012620
MIRT531442	hsa-miR-30a-3p	PAR-CLIP	22012620
MIRT531441	hsa-miR-30d-3p	PAR-CLIP	22012620
MIRT531440	hsa-miR-30e-3p	PAR-CLIP	22012620
MIRT531439	hsa-miR-633	PAR-CLIP	22012620
MIRT443685	hsa-miR-548an	PAR-CLIP	24398324
MIRT443684	hsa-miR-3714	PAR-CLIP	24398324
MIRT443683	hsa-miR-4418	PAR-CLIP	24398324
MIRT443682	hsa-miR-509-3-5p	PAR-CLIP	24398324
MIRT443681	hsa-miR-509-5p	PAR-CLIP	24398324
MIRT443680	hsa-miR-1910-3p	PAR-CLIP	24398324
MIRT443679	hsa-miR-6511a-5p	PAR-CLIP	24398324
MIRT443678	hsa-miR-4494	PAR-CLIP	24398324
MIRT443677	hsa-miR-1972	PAR-CLIP	24398324
MIRT443676	hsa-miR-1205	PAR-CLIP	24398324
MIRT443675	hsa-miR-4771	PAR-CLIP	24398324
MIRT443674	hsa-miR-6511b-5p	PAR-CLIP	24398324
MIRT443673	hsa-miR-6811-5p	PAR-CLIP	24398324
MIRT443685	hsa-miR-548an	PAR-CLIP	22291592
MIRT443684	hsa-miR-3714	PAR-CLIP	22291592
MIRT443683	hsa-miR-4418	PAR-CLIP	22291592
MIRT443682	hsa-miR-509-3-5p	PAR-CLIP	22291592
MIRT443681	hsa-miR-509-5p	PAR-CLIP	22291592
MIRT443680	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT443679	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT443678	hsa-miR-4494	PAR-CLIP	22291592
MIRT443677	hsa-miR-1972	PAR-CLIP	22291592
MIRT443676	hsa-miR-1205	PAR-CLIP	22291592
MIRT443675	hsa-miR-4771	PAR-CLIP	22291592
MIRT443674	hsa-miR-6511b-5p	PAR-CLIP	22291592
MIRT443673	hsa-miR-6811-5p	PAR-CLIP	22291592
MIRT443685	hsa-miR-548an	PAR-CLIP	22100165
MIRT443684	hsa-miR-3714	PAR-CLIP	22100165
MIRT443683	hsa-miR-4418	PAR-CLIP	22100165
MIRT443682	hsa-miR-509-3-5p	PAR-CLIP	22100165
MIRT443681	hsa-miR-509-5p	PAR-CLIP	22100165
MIRT443680	hsa-miR-1910-3p	PAR-CLIP	22100165
MIRT443679	hsa-miR-6511a-5p	PAR-CLIP	22100165
MIRT443678	hsa-miR-4494	PAR-CLIP	22100165
MIRT443677	hsa-miR-1972	PAR-CLIP	22100165
MIRT443676	hsa-miR-1205	PAR-CLIP	22100165
MIRT443675	hsa-miR-4771	PAR-CLIP	22100165
MIRT443674	hsa-miR-6511b-5p	PAR-CLIP	22100165
MIRT443673	hsa-miR-6811-5p	PAR-CLIP	22100165
MIRT440483	hsa-miR-381-3p	HITS-CLIP	24374217
MIRT440483	hsa-miR-381-3p	HITS-CLIP	24374217
MIRT564181	hsa-miR-3163	PAR-CLIP	27292025
MIRT664594	hsa-miR-4252	PAR-CLIP	27292025
MIRT664593	hsa-miR-5186	PAR-CLIP	27292025
MIRT675502	hsa-miR-6799-5p	PAR-CLIP	27292025
MIRT531439	hsa-miR-633	HITS-CLIP	27418678
MIRT531439	hsa-miR-633	HITS-CLIP	27418678
MIRT664600	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT664599	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT664597	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT664596	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT664595	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT695784	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT664594	hsa-miR-4252	HITS-CLIP	23313552
MIRT664601	hsa-miR-1273a	HITS-CLIP	23313552
MIRT695783	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT664591	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT664590	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT664589	hsa-miR-7703	HITS-CLIP	23313552
MIRT675510	hsa-miR-3614-5p	HITS-CLIP	23824327
MIRT675509	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT649068	hsa-miR-4284	HITS-CLIP	23824327
MIRT675508	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT675507	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT675506	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT675505	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT675504	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT675503	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT675502	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT675501	hsa-miR-7977	HITS-CLIP	23824327
MIRT675500	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT675499	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT675498	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT675497	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT675496	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT675495	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT675494	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT675493	hsa-miR-3689c	HITS-CLIP	23824327
MIRT675492	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT675491	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT675490	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT664602	hsa-miR-6501-3p	HITS-CLIP	23824327
MIRT664601	hsa-miR-1273a	HITS-CLIP	23824327
MIRT664600	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT664599	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT664597	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT664598	hsa-miR-598-5p	HITS-CLIP	23824327
MIRT664596	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT664595	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT664593	hsa-miR-5186	HITS-CLIP	23824327
MIRT664594	hsa-miR-4252	HITS-CLIP	23824327
MIRT664592	hsa-miR-542-3p	HITS-CLIP	23824327
MIRT664591	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT664590	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT664589	hsa-miR-7703	HITS-CLIP	23824327
MIRT664588	hsa-miR-7705	HITS-CLIP	23824327
MIRT664587	hsa-miR-103b	HITS-CLIP	23824327
MIRT664586	hsa-miR-1267	HITS-CLIP	23824327
MIRT664585	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT664584	hsa-miR-4466	HITS-CLIP	23824327
MIRT664583	hsa-miR-675-5p	HITS-CLIP	23824327
MIRT664582	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT664581	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT664580	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT664579	hsa-miR-5698	HITS-CLIP	23824327
MIRT649077	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT649076	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT649075	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT649074	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT649073	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT649072	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT649071	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT649070	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT649069	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT649068	hsa-miR-4284	HITS-CLIP	23824327
MIRT649067	hsa-miR-382-3p	HITS-CLIP	23824327
MIRT649066	hsa-miR-1288-5p	HITS-CLIP	23824327
MIRT649065	hsa-miR-548aw	HITS-CLIP	23824327
MIRT649064	hsa-miR-518a-5p	HITS-CLIP	23824327
MIRT649063	hsa-miR-527	HITS-CLIP	23824327
MIRT649062	hsa-miR-450b-5p	HITS-CLIP	23824327
MIRT649061	hsa-miR-507	HITS-CLIP	23824327
MIRT649060	hsa-miR-557	HITS-CLIP	23824327
MIRT649059	hsa-miR-3680-3p	HITS-CLIP	23824327
MIRT564181	hsa-miR-3163	PAR-CLIP	20371350
MIRT531439	hsa-miR-633	PAR-CLIP	20371350
MIRT531453	hsa-miR-4280	PAR-CLIP	22012620
MIRT531452	hsa-miR-205-3p	PAR-CLIP	22012620
MIRT531451	hsa-miR-936	PAR-CLIP	22012620
MIRT531450	hsa-miR-199a-3p	PAR-CLIP	22012620
MIRT531449	hsa-miR-199b-3p	PAR-CLIP	22012620
MIRT531448	hsa-miR-3129-5p	PAR-CLIP	22012620
MIRT531447	hsa-miR-29a-5p	PAR-CLIP	22012620
MIRT531446	hsa-miR-494-3p	PAR-CLIP	22012620
MIRT531445	hsa-miR-142-3p	PAR-CLIP	22012620
MIRT531444	hsa-miR-222-5p	PAR-CLIP	22012620
MIRT531443	hsa-miR-510-3p	PAR-CLIP	22012620
MIRT531442	hsa-miR-30a-3p	PAR-CLIP	22012620
MIRT531441	hsa-miR-30d-3p	PAR-CLIP	22012620
MIRT531440	hsa-miR-30e-3p	PAR-CLIP	22012620
MIRT531439	hsa-miR-633	PAR-CLIP	22012620
MIRT443685	hsa-miR-548an	PAR-CLIP	24398324
MIRT443684	hsa-miR-3714	PAR-CLIP	24398324
MIRT443683	hsa-miR-4418	PAR-CLIP	24398324
MIRT443682	hsa-miR-509-3-5p	PAR-CLIP	24398324
MIRT443681	hsa-miR-509-5p	PAR-CLIP	24398324
MIRT443680	hsa-miR-1910-3p	PAR-CLIP	24398324
MIRT443679	hsa-miR-6511a-5p	PAR-CLIP	24398324
MIRT443678	hsa-miR-4494	PAR-CLIP	24398324
MIRT443677	hsa-miR-1972	PAR-CLIP	24398324
MIRT443676	hsa-miR-1205	PAR-CLIP	24398324
MIRT443675	hsa-miR-4771	PAR-CLIP	24398324
MIRT443674	hsa-miR-6511b-5p	PAR-CLIP	24398324
MIRT443673	hsa-miR-6811-5p	PAR-CLIP	24398324
MIRT443685	hsa-miR-548an	PAR-CLIP	22291592
MIRT443684	hsa-miR-3714	PAR-CLIP	22291592
MIRT443683	hsa-miR-4418	PAR-CLIP	22291592
MIRT443682	hsa-miR-509-3-5p	PAR-CLIP	22291592
MIRT443681	hsa-miR-509-5p	PAR-CLIP	22291592
MIRT443680	hsa-miR-1910-3p	PAR-CLIP	22291592
MIRT443679	hsa-miR-6511a-5p	PAR-CLIP	22291592
MIRT443678	hsa-miR-4494	PAR-CLIP	22291592
MIRT443677	hsa-miR-1972	PAR-CLIP	22291592
MIRT443676	hsa-miR-1205	PAR-CLIP	22291592
MIRT443675	hsa-miR-4771	PAR-CLIP	22291592
MIRT443674	hsa-miR-6511b-5p	PAR-CLIP	22291592
MIRT443673	hsa-miR-6811-5p	PAR-CLIP	22291592
MIRT443685	hsa-miR-548an	PAR-CLIP	22100165
MIRT443684	hsa-miR-3714	PAR-CLIP	22100165
MIRT443683	hsa-miR-4418	PAR-CLIP	22100165
MIRT443682	hsa-miR-509-3-5p	PAR-CLIP	22100165
MIRT443681	hsa-miR-509-5p	PAR-CLIP	22100165
MIRT443680	hsa-miR-1910-3p	PAR-CLIP	22100165
MIRT443679	hsa-miR-6511a-5p	PAR-CLIP	22100165
MIRT443678	hsa-miR-4494	PAR-CLIP	22100165
MIRT443677	hsa-miR-1972	PAR-CLIP	22100165
MIRT443676	hsa-miR-1205	PAR-CLIP	22100165
MIRT443675	hsa-miR-4771	PAR-CLIP	22100165
MIRT443674	hsa-miR-6511b-5p	PAR-CLIP	22100165
MIRT443673	hsa-miR-6811-5p	PAR-CLIP	22100165
MIRT1055321	hsa-miR-1207-3p	CLIP-seq
MIRT1055322	hsa-miR-1297	CLIP-seq
MIRT1055323	hsa-miR-1305	CLIP-seq
MIRT1055324	hsa-miR-1323	CLIP-seq
MIRT1055325	hsa-miR-136	CLIP-seq
MIRT1055326	hsa-miR-155	CLIP-seq
MIRT1055327	hsa-miR-181a	CLIP-seq
MIRT1055328	hsa-miR-181b	CLIP-seq
MIRT1055329	hsa-miR-181c	CLIP-seq
MIRT1055330	hsa-miR-181d	CLIP-seq
MIRT1055331	hsa-miR-26a	CLIP-seq
MIRT1055332	hsa-miR-26b	CLIP-seq
MIRT1055333	hsa-miR-2909	CLIP-seq
MIRT1055334	hsa-miR-298	CLIP-seq
MIRT1055335	hsa-miR-300	CLIP-seq
MIRT1055336	hsa-miR-3128	CLIP-seq
MIRT1055337	hsa-miR-3145-3p	CLIP-seq
MIRT1055338	hsa-miR-3613-3p	CLIP-seq
MIRT1055339	hsa-miR-3646	CLIP-seq
MIRT1055340	hsa-miR-365	CLIP-seq
MIRT1055341	hsa-miR-374a	CLIP-seq
MIRT1055342	hsa-miR-374b	CLIP-seq
MIRT1055343	hsa-miR-381	CLIP-seq
MIRT1055344	hsa-miR-3974	CLIP-seq
MIRT1055345	hsa-miR-4251	CLIP-seq
MIRT1055346	hsa-miR-4262	CLIP-seq
MIRT1055347	hsa-miR-4278	CLIP-seq
MIRT1055348	hsa-miR-4303	CLIP-seq
MIRT1055349	hsa-miR-4314	CLIP-seq
MIRT1055350	hsa-miR-4329	CLIP-seq
MIRT1055351	hsa-miR-4455	CLIP-seq
MIRT1055352	hsa-miR-4465	CLIP-seq
MIRT1055353	hsa-miR-4470	CLIP-seq
MIRT1055354	hsa-miR-4489	CLIP-seq
MIRT1055355	hsa-miR-4659a-3p	CLIP-seq
MIRT1055356	hsa-miR-4659b-3p	CLIP-seq
MIRT1055357	hsa-miR-4688	CLIP-seq
MIRT1055358	hsa-miR-4699-3p	CLIP-seq
MIRT1055359	hsa-miR-4735-5p	CLIP-seq
MIRT1055360	hsa-miR-4775	CLIP-seq
MIRT1055361	hsa-miR-4778-5p	CLIP-seq
MIRT1055362	hsa-miR-513b	CLIP-seq
MIRT1055363	hsa-miR-515-5p	CLIP-seq
MIRT1055364	hsa-miR-548aa	CLIP-seq
MIRT1055365	hsa-miR-548o	CLIP-seq
MIRT1055366	hsa-miR-549	CLIP-seq
MIRT1055367	hsa-miR-590-3p	CLIP-seq
MIRT1055368	hsa-miR-607	CLIP-seq
MIRT1055369	hsa-miR-609	CLIP-seq
MIRT1055370	hsa-miR-616	CLIP-seq
MIRT1055371	hsa-miR-624	CLIP-seq
MIRT1055372	hsa-miR-944	CLIP-seq
MIRT1055321	hsa-miR-1207-3p	CLIP-seq
MIRT2012673	hsa-miR-1263	CLIP-seq
MIRT2012674	hsa-miR-3168	CLIP-seq
MIRT1055341	hsa-miR-374a	CLIP-seq
MIRT1055342	hsa-miR-374b	CLIP-seq
MIRT2012675	hsa-miR-3919	CLIP-seq
MIRT2012676	hsa-miR-3942-3p	CLIP-seq
MIRT2012677	hsa-miR-4276	CLIP-seq
MIRT2012678	hsa-miR-4328	CLIP-seq
MIRT1055351	hsa-miR-4455	CLIP-seq
MIRT2012679	hsa-miR-448	CLIP-seq
MIRT2012680	hsa-miR-4756-3p	CLIP-seq
MIRT2012681	hsa-miR-4759	CLIP-seq
MIRT1055360	hsa-miR-4775	CLIP-seq
MIRT2012682	hsa-miR-487a	CLIP-seq
MIRT1055362	hsa-miR-513b	CLIP-seq
MIRT1055364	hsa-miR-548aa	CLIP-seq
MIRT2012683	hsa-miR-579	CLIP-seq
MIRT2012684	hsa-miR-587	CLIP-seq
MIRT2012685	hsa-miR-604	CLIP-seq
MIRT1055369	hsa-miR-609	CLIP-seq
MIRT1055370	hsa-miR-616	CLIP-seq
MIRT2012686	hsa-miR-647	CLIP-seq
MIRT2012687	hsa-miR-664	CLIP-seq
MIRT1055372	hsa-miR-944	CLIP-seq
MIRT2245014	hsa-miR-128	CLIP-seq
MIRT1055323	hsa-miR-1305	CLIP-seq
MIRT1055324	hsa-miR-1323	CLIP-seq
MIRT2245015	hsa-miR-144	CLIP-seq
MIRT1055327	hsa-miR-181a	CLIP-seq
MIRT1055328	hsa-miR-181b	CLIP-seq
MIRT1055329	hsa-miR-181c	CLIP-seq
MIRT1055330	hsa-miR-181d	CLIP-seq
MIRT2245016	hsa-miR-27a	CLIP-seq
MIRT2245017	hsa-miR-27b	CLIP-seq
MIRT1055333	hsa-miR-2909	CLIP-seq
MIRT2245018	hsa-miR-3117-3p	CLIP-seq
MIRT2245019	hsa-miR-3136-3p	CLIP-seq
MIRT2012674	hsa-miR-3168	CLIP-seq
MIRT2245020	hsa-miR-3169	CLIP-seq
MIRT2245021	hsa-miR-328	CLIP-seq
MIRT2245022	hsa-miR-338-5p	CLIP-seq
MIRT1055341	hsa-miR-374a	CLIP-seq
MIRT1055342	hsa-miR-374b	CLIP-seq
MIRT2012675	hsa-miR-3919	CLIP-seq
MIRT2012676	hsa-miR-3942-3p	CLIP-seq
MIRT1055346	hsa-miR-4262	CLIP-seq
MIRT1055347	hsa-miR-4278	CLIP-seq
MIRT2245023	hsa-miR-4293	CLIP-seq
MIRT2012678	hsa-miR-4328	CLIP-seq
MIRT2245024	hsa-miR-4452	CLIP-seq
MIRT1055351	hsa-miR-4455	CLIP-seq
MIRT2012679	hsa-miR-448	CLIP-seq
MIRT1055354	hsa-miR-4489	CLIP-seq
MIRT1055357	hsa-miR-4688	CLIP-seq
MIRT2245025	hsa-miR-4700-3p	CLIP-seq
MIRT1055359	hsa-miR-4735-5p	CLIP-seq
MIRT2012680	hsa-miR-4756-3p	CLIP-seq
MIRT2012681	hsa-miR-4759	CLIP-seq
MIRT1055360	hsa-miR-4775	CLIP-seq
MIRT2245026	hsa-miR-4778-3p	CLIP-seq
MIRT2245027	hsa-miR-513a-5p	CLIP-seq
MIRT1055364	hsa-miR-548aa	CLIP-seq
MIRT1055365	hsa-miR-548o	CLIP-seq
MIRT2012684	hsa-miR-587	CLIP-seq
MIRT1055367	hsa-miR-590-3p	CLIP-seq
MIRT2245028	hsa-miR-592	CLIP-seq
MIRT2245029	hsa-miR-596	CLIP-seq
MIRT2245030	hsa-miR-597	CLIP-seq
MIRT2012685	hsa-miR-604	CLIP-seq
MIRT1055368	hsa-miR-607	CLIP-seq
MIRT1055369	hsa-miR-609	CLIP-seq
MIRT2012686	hsa-miR-647	CLIP-seq
MIRT2012687	hsa-miR-664	CLIP-seq
MIRT1055372	hsa-miR-944	CLIP-seq
MIRT1055321	hsa-miR-1207-3p	CLIP-seq
MIRT2245014	hsa-miR-128	CLIP-seq
MIRT2245015	hsa-miR-144	CLIP-seq
MIRT2245016	hsa-miR-27a	CLIP-seq
MIRT2245017	hsa-miR-27b	CLIP-seq
MIRT2012679	hsa-miR-448	CLIP-seq
MIRT2245026	hsa-miR-4778-3p	CLIP-seq
MIRT2245027	hsa-miR-513a-5p	CLIP-seq
MIRT2547917	hsa-miR-1253	CLIP-seq
MIRT2547918	hsa-miR-1273e	CLIP-seq
MIRT2547919	hsa-miR-1287	CLIP-seq
MIRT1055323	hsa-miR-1305	CLIP-seq
MIRT2547920	hsa-miR-1322	CLIP-seq
MIRT1055324	hsa-miR-1323	CLIP-seq
MIRT1055327	hsa-miR-181a	CLIP-seq
MIRT1055328	hsa-miR-181b	CLIP-seq
MIRT1055329	hsa-miR-181c	CLIP-seq
MIRT1055330	hsa-miR-181d	CLIP-seq
MIRT2547921	hsa-miR-190	CLIP-seq
MIRT2547922	hsa-miR-190b	CLIP-seq
MIRT1055333	hsa-miR-2909	CLIP-seq
MIRT2547923	hsa-miR-3126-3p	CLIP-seq
MIRT2547924	hsa-miR-3135b	CLIP-seq
MIRT2012674	hsa-miR-3168	CLIP-seq
MIRT2547925	hsa-miR-3176	CLIP-seq
MIRT2245022	hsa-miR-338-5p	CLIP-seq
MIRT2547926	hsa-miR-369-3p	CLIP-seq
MIRT1055341	hsa-miR-374a	CLIP-seq
MIRT1055342	hsa-miR-374b	CLIP-seq
MIRT2547927	hsa-miR-3922-3p	CLIP-seq
MIRT2547928	hsa-miR-3926	CLIP-seq
MIRT1055344	hsa-miR-3974	CLIP-seq
MIRT1055345	hsa-miR-4251	CLIP-seq
MIRT1055346	hsa-miR-4262	CLIP-seq
MIRT1055347	hsa-miR-4278	CLIP-seq
MIRT1055348	hsa-miR-4303	CLIP-seq
MIRT1055350	hsa-miR-4329	CLIP-seq
MIRT2012679	hsa-miR-448	CLIP-seq
MIRT2547929	hsa-miR-4480	CLIP-seq
MIRT1055354	hsa-miR-4489	CLIP-seq
MIRT2547930	hsa-miR-4528	CLIP-seq
MIRT2547931	hsa-miR-4677-3p	CLIP-seq
MIRT2547932	hsa-miR-4679	CLIP-seq
MIRT1055357	hsa-miR-4688	CLIP-seq
MIRT2547933	hsa-miR-4728-3p	CLIP-seq
MIRT2547934	hsa-miR-4729	CLIP-seq
MIRT1055359	hsa-miR-4735-5p	CLIP-seq
MIRT1055360	hsa-miR-4775	CLIP-seq
MIRT1055361	hsa-miR-4778-5p	CLIP-seq
MIRT2547935	hsa-miR-491-3p	CLIP-seq
MIRT2547936	hsa-miR-517b	CLIP-seq
MIRT1055364	hsa-miR-548aa	CLIP-seq
MIRT1055365	hsa-miR-548o	CLIP-seq
MIRT2547937	hsa-miR-548s	CLIP-seq
MIRT1055366	hsa-miR-549	CLIP-seq
MIRT2547938	hsa-miR-556-5p	CLIP-seq
MIRT2012683	hsa-miR-579	CLIP-seq
MIRT2547939	hsa-miR-586	CLIP-seq
MIRT1055367	hsa-miR-590-3p	CLIP-seq
MIRT1055368	hsa-miR-607	CLIP-seq
MIRT1055371	hsa-miR-624	CLIP-seq
MIRT2547940	hsa-miR-627	CLIP-seq
MIRT2547941	hsa-miR-656	CLIP-seq
MIRT2012687	hsa-miR-664	CLIP-seq
MIRT2547942	hsa-miR-924	CLIP-seq
MIRT2547918	hsa-miR-1273e	CLIP-seq
MIRT2547919	hsa-miR-1287	CLIP-seq
MIRT1055323	hsa-miR-1305	CLIP-seq
MIRT2547920	hsa-miR-1322	CLIP-seq
MIRT1055324	hsa-miR-1323	CLIP-seq
MIRT1055327	hsa-miR-181a	CLIP-seq
MIRT1055328	hsa-miR-181b	CLIP-seq
MIRT1055329	hsa-miR-181c	CLIP-seq
MIRT1055330	hsa-miR-181d	CLIP-seq
MIRT2547921	hsa-miR-190	CLIP-seq
MIRT2547922	hsa-miR-190b	CLIP-seq
MIRT1055333	hsa-miR-2909	CLIP-seq
MIRT2547923	hsa-miR-3126-3p	CLIP-seq
MIRT2547924	hsa-miR-3135b	CLIP-seq
MIRT2012674	hsa-miR-3168	CLIP-seq
MIRT2547925	hsa-miR-3176	CLIP-seq
MIRT2245022	hsa-miR-338-5p	CLIP-seq
MIRT2547926	hsa-miR-369-3p	CLIP-seq
MIRT1055341	hsa-miR-374a	CLIP-seq
MIRT1055342	hsa-miR-374b	CLIP-seq
MIRT2547927	hsa-miR-3922-3p	CLIP-seq
MIRT2547928	hsa-miR-3926	CLIP-seq
MIRT1055344	hsa-miR-3974	CLIP-seq
MIRT1055345	hsa-miR-4251	CLIP-seq
MIRT1055346	hsa-miR-4262	CLIP-seq
MIRT1055347	hsa-miR-4278	CLIP-seq
MIRT1055348	hsa-miR-4303	CLIP-seq
MIRT1055350	hsa-miR-4329	CLIP-seq
MIRT2012679	hsa-miR-448	CLIP-seq
MIRT2547929	hsa-miR-4480	CLIP-seq
MIRT1055354	hsa-miR-4489	CLIP-seq
MIRT2547931	hsa-miR-4677-3p	CLIP-seq
MIRT2547932	hsa-miR-4679	CLIP-seq
MIRT1055357	hsa-miR-4688	CLIP-seq
MIRT2547933	hsa-miR-4728-3p	CLIP-seq
MIRT2547934	hsa-miR-4729	CLIP-seq
MIRT1055359	hsa-miR-4735-5p	CLIP-seq
MIRT1055360	hsa-miR-4775	CLIP-seq
MIRT1055361	hsa-miR-4778-5p	CLIP-seq
MIRT2547935	hsa-miR-491-3p	CLIP-seq
MIRT2547936	hsa-miR-517b	CLIP-seq
MIRT1055364	hsa-miR-548aa	CLIP-seq
MIRT1055365	hsa-miR-548o	CLIP-seq
MIRT2547937	hsa-miR-548s	CLIP-seq
MIRT1055366	hsa-miR-549	CLIP-seq
MIRT2547938	hsa-miR-556-5p	CLIP-seq
MIRT2012683	hsa-miR-579	CLIP-seq
MIRT1055367	hsa-miR-590-3p	CLIP-seq
MIRT1055368	hsa-miR-607	CLIP-seq
MIRT1055371	hsa-miR-624	CLIP-seq
MIRT2547940	hsa-miR-627	CLIP-seq
MIRT2547941	hsa-miR-656	CLIP-seq
MIRT2012687	hsa-miR-664	CLIP-seq
MIRT2547942	hsa-miR-924	CLIP-seq

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001968	Function	Fibronectin binding	IEA
GO:0004303	Function	Estradiol 17-beta-dehydrogenase activity	IEA
GO:0005515	Function	Protein binding	IPI	20937905, 24169621, 25416956, 32296183, 32814053
GO:0005518	Function	Collagen binding	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0006703	Process	Estrogen biosynthetic process	IEA
GO:0008201	Function	Heparin binding	IEA
GO:0009923	Component	Fatty acid elongase complex	IDA	25003994
GO:0010811	Process	Positive regulation of cell-substrate adhesion	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0030198	Process	Extracellular matrix organization	IEA
GO:0031012	Component	Extracellular matrix	IEA
GO:0035338	Process	Long-chain fatty-acyl-CoA biosynthetic process	TAS
GO:0050062	Function	Long-chain-fatty-acyl-CoA reductase activity	IDA	25003994
GO:0102339	Function	3-oxo-arachidoyl-CoA reductase activity	IEA
GO:0102340	Function	3-oxo-behenoyl-CoA reductase activity	IEA
GO:0102341	Function	3-oxo-lignoceroyl-CoA reductase activity	IEA
GO:0102342	Function	3-oxo-cerotoyl-CoA reductase activity	IEA

MIM	HGNC	e!Ensembl
609574	18646	ENSG00000149084

Protein

UniProt ID

Q53GQ0

Protein name

Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1)

Protein function

Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cy

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00106	adh_short	51 → 248	short chain dehydrogenase	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets. {ECO:0000269|PubMed:12482854, ECO:0000269|PubMed:16113833, ECO:0000269|PubMed:16166196}.

Sequence

MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTD
GIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKT
GLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERS
KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLA
KIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKS
TRAHYLKKTKKN

Sequence length

312

Interactions

View interactions

	KEGG		Reactome
	Fatty acid elongation Steroid hormone biosynthesis Biosynthesis of unsaturated fatty acids Metabolic pathways Fatty acid metabolism		Androgen biosynthesis Synthesis of very long-chain fatty acyl-CoAs

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237 View all (293 more)	28566273
Neuroblastoma	Neuroblastoma	rs113994087, rs113994089, rs281864719, rs863225285, rs863225284, rs863225283, rs281864720, rs863225282, rs863225281, rs1057519698, rs915983602, rs1469271544	22941191

Show/Hide Unknown Diseases (5)

Disease term	Disease name	Source
Unknown
Diabetes	Diabetes	GWAS
Coronary artery disease	Coronary artery disease	GWAS
Hypertension	Hypertension	GWAS
Hyperopia	Hyperopia	GWAS
Metabolic Syndrome	Metabolic Syndrome	GWAS

Show/Hide Text Mining Associations (22)

Disease Name	Relationship Type	References
Associations from Text Mining
Alcoholism	Associate	35404482
Breast Neoplasms	Associate	31302749, 31671023
Carcinoma Ductal Breast	Associate	22903146
Colorectal Neoplasms	Stimulate	33118286, 35779418
Colorectal Neoplasms	Associate	33118286
Death	Associate	33118286
Diabetes Mellitus	Associate	35320353
Diabetes Mellitus Type 2	Stimulate	32340285
Diabetes Mellitus Type 2	Associate	40596821
Head and Neck Neoplasms	Associate	35404482
Melanoma	Associate	30734280
Melanoma Cutaneous Malignant	Associate	30734280
Migraine Disorders	Associate	40596821
Mouth Neoplasms	Associate	35404482
Neoplasms	Associate	22903146
Neuroblastoma	Associate	21436895, 23222812, 25312269
Obesity	Associate	32340285, 35779418
Oropharyngeal Neoplasms	Associate	35404482
Ovarian Neoplasms	Associate	22903146
Prostatitis	Associate	21900597
Squamous Cell Carcinoma of Head and Neck	Associate	35404482
Thrombocytosis	Associate	29420626

HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12)