Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	50863
Gene name Gene Name - the full gene name approved by the HGNC.	Neurotrimin
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NTM
Synonyms (NCBI Gene) Gene synonyms aliases	CEPU-1, HNT, IGLON2, NTRI
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q25
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the IgLON (LAMP, OBCAM, Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules. The encoded protein may promote neurite outgrowth and adhesion via a homophilic

Show/Hide all(95)

miRTarBase ID	miRNA	Experiments	Reference
MIRT006824	hsa-miR-182-5p	Luciferase reporter assay, Western blot	22917588
MIRT006824	hsa-miR-182-5p	Luciferase reporter assay, Western blot	22917588
MIRT645476	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT645475	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT645474	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT645473	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT645476	hsa-miR-362-5p	HITS-CLIP	23824327
MIRT645475	hsa-miR-500b-5p	HITS-CLIP	23824327
MIRT645474	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT645473	hsa-miR-340-5p	HITS-CLIP	23824327
MIRT1196059	hsa-miR-1207-3p	CLIP-seq
MIRT1196060	hsa-miR-1825	CLIP-seq
MIRT1196061	hsa-miR-199a-5p	CLIP-seq
MIRT1196062	hsa-miR-199b-5p	CLIP-seq
MIRT1196063	hsa-miR-3159	CLIP-seq
MIRT1196064	hsa-miR-3545-5p	CLIP-seq
MIRT1196065	hsa-miR-369-3p	CLIP-seq
MIRT1196066	hsa-miR-374a	CLIP-seq
MIRT1196067	hsa-miR-374b	CLIP-seq
MIRT1196068	hsa-miR-3925-3p	CLIP-seq
MIRT1196069	hsa-miR-513b	CLIP-seq
MIRT1196070	hsa-miR-568	CLIP-seq
MIRT1196071	hsa-miR-766	CLIP-seq
MIRT1196072	hsa-miR-1225-3p	CLIP-seq
MIRT1196073	hsa-miR-1233	CLIP-seq
MIRT1196074	hsa-miR-129-3p	CLIP-seq
MIRT1196075	hsa-miR-3929	CLIP-seq
MIRT1196076	hsa-miR-4265	CLIP-seq
MIRT1196077	hsa-miR-4296	CLIP-seq
MIRT1196078	hsa-miR-4322	CLIP-seq
MIRT1196079	hsa-miR-4417	CLIP-seq
MIRT1196080	hsa-miR-4419b	CLIP-seq
MIRT1196081	hsa-miR-4478	CLIP-seq
MIRT1196082	hsa-miR-4663	CLIP-seq
MIRT1196083	hsa-miR-485-5p	CLIP-seq
MIRT1551898	hsa-miR-4434	CLIP-seq
MIRT1551899	hsa-miR-4436b-3p	CLIP-seq
MIRT1551900	hsa-miR-4516	CLIP-seq
MIRT1551901	hsa-miR-4531	CLIP-seq
MIRT1551902	hsa-miR-614	CLIP-seq
MIRT1556743	hsa-miR-4532	CLIP-seq
MIRT1196060	hsa-miR-1825	CLIP-seq
MIRT1196061	hsa-miR-199a-5p	CLIP-seq
MIRT1196062	hsa-miR-199b-5p	CLIP-seq
MIRT2056885	hsa-miR-323-5p	CLIP-seq
MIRT1196064	hsa-miR-3545-5p	CLIP-seq
MIRT1196068	hsa-miR-3925-3p	CLIP-seq
MIRT2056886	hsa-miR-4467	CLIP-seq
MIRT1556743	hsa-miR-4532	CLIP-seq
MIRT1196071	hsa-miR-766	CLIP-seq
MIRT2056887	hsa-miR-876-3p	CLIP-seq
MIRT2583424	hsa-miR-1301	CLIP-seq
MIRT1196060	hsa-miR-1825	CLIP-seq
MIRT1196061	hsa-miR-199a-5p	CLIP-seq
MIRT1196062	hsa-miR-199b-5p	CLIP-seq
MIRT2583425	hsa-miR-2116	CLIP-seq
MIRT2583426	hsa-miR-3122	CLIP-seq
MIRT2583427	hsa-miR-3153	CLIP-seq
MIRT1196063	hsa-miR-3159	CLIP-seq
MIRT2583428	hsa-miR-3163	CLIP-seq
MIRT1196064	hsa-miR-3545-5p	CLIP-seq
MIRT1196065	hsa-miR-369-3p	CLIP-seq
MIRT1196066	hsa-miR-374a	CLIP-seq
MIRT1196067	hsa-miR-374b	CLIP-seq
MIRT2583429	hsa-miR-377	CLIP-seq
MIRT2583430	hsa-miR-3910	CLIP-seq
MIRT2583431	hsa-miR-3913-5p	CLIP-seq
MIRT2583432	hsa-miR-3919	CLIP-seq
MIRT1196068	hsa-miR-3925-3p	CLIP-seq
MIRT2583433	hsa-miR-3941	CLIP-seq
MIRT2583434	hsa-miR-4275	CLIP-seq
MIRT2583435	hsa-miR-4327	CLIP-seq
MIRT2583436	hsa-miR-4455	CLIP-seq
MIRT2583437	hsa-miR-466	CLIP-seq
MIRT2583438	hsa-miR-4660	CLIP-seq
MIRT2583439	hsa-miR-4668-5p	CLIP-seq
MIRT2583440	hsa-miR-4672	CLIP-seq
MIRT2583441	hsa-miR-4677-5p	CLIP-seq
MIRT2583442	hsa-miR-4711-5p	CLIP-seq
MIRT2583443	hsa-miR-4719	CLIP-seq
MIRT2583444	hsa-miR-4731-3p	CLIP-seq
MIRT2583445	hsa-miR-4756-3p	CLIP-seq
MIRT2583446	hsa-miR-4801	CLIP-seq
MIRT2583447	hsa-miR-5047	CLIP-seq
MIRT2583448	hsa-miR-548an	CLIP-seq
MIRT1196070	hsa-miR-568	CLIP-seq
MIRT2583449	hsa-miR-583	CLIP-seq
MIRT2583450	hsa-miR-618	CLIP-seq
MIRT1196071	hsa-miR-766	CLIP-seq
MIRT2686656	hsa-miR-3183	CLIP-seq
MIRT2686657	hsa-miR-339-5p	CLIP-seq
MIRT2686658	hsa-miR-4421	CLIP-seq
MIRT2686659	hsa-miR-4723-3p	CLIP-seq
MIRT2686660	hsa-miR-593	CLIP-seq
MIRT2686661	hsa-miR-642a	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21982860, 25416956, 31515488, 32296183
GO:0005576	Component	Extracellular region	TAS
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007155	Process	Cell adhesion	IEA
GO:0007155	Process	Cell adhesion	NAS	7891157
GO:0008038	Process	Neuron recognition	IEA
GO:0008038	Process	Neuron recognition	TAS	7891157
GO:0016020	Component	Membrane	IEA
GO:0098552	Component	Side of membrane	IEA

MIM	HGNC	e!Ensembl
607938	17941	ENSG00000182667

Protein

UniProt ID

Q9P121

Protein name

Neurotrimin (hNT) (IgLON family member 2)

Protein function

Neural cell adhesion molecule.

PDB

6DLF

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07679	I-set	36 → 132	Immunoglobulin I-set domain	Domain
PF13927	Ig_3	135 → 205		Domain
PF13927	Ig_3	222 → 299		Domain

Sequence

MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTID
NRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTD
NHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFV
SEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGT
LQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNK
LGHTNASIMLFGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF

Sequence length

344

Interactions

View interactions

	Reactome
			Post-translational modification: synthesis of GPI-anchored proteins

Show/Hide Unknown Diseases (10)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Astrocytoma	Astrocytoma, Pilocytic astrocytoma	N/A	N/A	GWAS
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Connective Tissue Disease	Connective tissue disorder	N/A	N/A	ClinVar
Dementia	Dementia	N/A	N/A	GWAS
Insomnia	Insomnia	N/A	N/A	GWAS
Lung adenocarcinoma	Familial lung adenocarcinoma	N/A	N/A	GWAS
Metabolic Syndrome	Metabolic syndrome, Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome	N/A	N/A	GWAS
Myopia	Myopia	N/A	N/A	GWAS
Prostate cancer	Prostate cancer	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (18)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Aortic Aneurysm Thoracic	Associate	23054244
Attention Deficit Disorder with Hyperactivity	Associate	27021288
Autism Spectrum Disorder	Associate	32807774
Carcinogenesis	Associate	23495067
Carcinoma Ovarian Epithelial	Associate	16115914
Colorectal Neoplasms	Associate	35991839
Congenital disorder of glycosylation type 1A	Associate	23054244
Developmental Disabilities	Associate	23495067
Glaucoma Open Angle	Associate	22661486
Idiopathic Pulmonary Fibrosis	Associate	30720061
Intracranial Aneurysm	Associate	23054244, 34668355
Leiomyoma	Stimulate	32033718
Neoplasms	Associate	16115914, 23495067
Osteogenesis imperfecta type 1A	Associate	34668355
Ovarian Neoplasms	Associate	16115914
Personality Disorders	Associate	27021288
Prostatic Neoplasms	Associate	33934205
Squamous Cell Carcinoma of Head and Neck	Associate	28814981

NTM (neurotrimin)