Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	50804
Gene name Gene Name - the full gene name approved by the HGNC.	Myelin expression factor 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MYEF2
Synonyms (NCBI Gene) Gene synonyms aliases	HsT18564, MEF-2, MST156, MSTP156, myEF-2
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q21.1

Show/Hide all(291)

miRTarBase ID	miRNA	Experiments	Reference
MIRT029056	hsa-miR-26b-5p	Microarray	19088304
MIRT030757	hsa-miR-21-5p	Microarray	18591254
MIRT049561	hsa-miR-92a-3p	CLASH	23622248
MIRT047609	hsa-miR-10a-5p	CLASH	23622248
MIRT045916	hsa-miR-125b-5p	CLASH	23622248
MIRT720178	hsa-miR-548e-5p	HITS-CLIP	19536157
MIRT720177	hsa-miR-7-1-3p	HITS-CLIP	19536157
MIRT720176	hsa-miR-7-2-3p	HITS-CLIP	19536157
MIRT720175	hsa-miR-3065-5p	HITS-CLIP	19536157
MIRT000385	hsa-miR-1-3p	PAR-CLIP	22291592
MIRT498128	hsa-miR-206	PAR-CLIP	22291592
MIRT498127	hsa-miR-613	PAR-CLIP	22291592
MIRT446741	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT446740	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT446739	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT446738	hsa-miR-4635	PAR-CLIP	22100165
MIRT720178	hsa-miR-548e-5p	HITS-CLIP	19536157
MIRT720177	hsa-miR-7-1-3p	HITS-CLIP	19536157
MIRT720176	hsa-miR-7-2-3p	HITS-CLIP	19536157
MIRT720175	hsa-miR-3065-5p	HITS-CLIP	19536157
MIRT000385	hsa-miR-1-3p	PAR-CLIP	22291592
MIRT498128	hsa-miR-206	PAR-CLIP	22291592
MIRT498127	hsa-miR-613	PAR-CLIP	22291592
MIRT446741	hsa-miR-548c-3p	PAR-CLIP	22100165
MIRT446740	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT446739	hsa-miR-590-3p	PAR-CLIP	22100165
MIRT446738	hsa-miR-4635	PAR-CLIP	22100165
MIRT1167982	hsa-miR-1	CLIP-seq
MIRT1167983	hsa-miR-101	CLIP-seq
MIRT1167984	hsa-miR-1243	CLIP-seq
MIRT1167985	hsa-miR-1256	CLIP-seq
MIRT1167986	hsa-miR-1268	CLIP-seq
MIRT1167987	hsa-miR-1268b	CLIP-seq
MIRT1167988	hsa-miR-1275	CLIP-seq
MIRT1167989	hsa-miR-1285	CLIP-seq
MIRT1167990	hsa-miR-1305	CLIP-seq
MIRT1167991	hsa-miR-139-5p	CLIP-seq
MIRT1167992	hsa-miR-144	CLIP-seq
MIRT1167993	hsa-miR-2114	CLIP-seq
MIRT1167994	hsa-miR-3065-3p	CLIP-seq
MIRT1167995	hsa-miR-3119	CLIP-seq
MIRT1167996	hsa-miR-3140-3p	CLIP-seq
MIRT1167997	hsa-miR-3148	CLIP-seq
MIRT1167998	hsa-miR-3187-3p	CLIP-seq
MIRT1167999	hsa-miR-3187-5p	CLIP-seq
MIRT1168000	hsa-miR-338-5p	CLIP-seq
MIRT1168001	hsa-miR-3613-3p	CLIP-seq
MIRT1168002	hsa-miR-3622b-5p	CLIP-seq
MIRT1168003	hsa-miR-3653	CLIP-seq
MIRT1168004	hsa-miR-3658	CLIP-seq
MIRT1168005	hsa-miR-3671	CLIP-seq
MIRT1168006	hsa-miR-371-5p	CLIP-seq
MIRT1168007	hsa-miR-371b-5p	CLIP-seq
MIRT1168008	hsa-miR-421	CLIP-seq
MIRT1168009	hsa-miR-4259	CLIP-seq
MIRT1168010	hsa-miR-4260	CLIP-seq
MIRT1168011	hsa-miR-4263	CLIP-seq
MIRT1168012	hsa-miR-4291	CLIP-seq
MIRT1168013	hsa-miR-4435	CLIP-seq
MIRT1168014	hsa-miR-4528	CLIP-seq
MIRT1168015	hsa-miR-4529-5p	CLIP-seq
MIRT1168016	hsa-miR-4642	CLIP-seq
MIRT1168017	hsa-miR-4661-5p	CLIP-seq
MIRT1168018	hsa-miR-4665-5p	CLIP-seq
MIRT1168019	hsa-miR-4666-3p	CLIP-seq
MIRT1168020	hsa-miR-4668-5p	CLIP-seq
MIRT1168021	hsa-miR-4701-5p	CLIP-seq
MIRT1168022	hsa-miR-4711-3p	CLIP-seq
MIRT1168023	hsa-miR-4715-5p	CLIP-seq
MIRT1168024	hsa-miR-4720-3p	CLIP-seq
MIRT1168025	hsa-miR-4735-5p	CLIP-seq
MIRT1168026	hsa-miR-4804-3p	CLIP-seq
MIRT1168027	hsa-miR-508-3p	CLIP-seq
MIRT1168028	hsa-miR-548a-3p	CLIP-seq
MIRT1168029	hsa-miR-548aa	CLIP-seq
MIRT1168030	hsa-miR-548ac	CLIP-seq
MIRT1168031	hsa-miR-548ae	CLIP-seq
MIRT1168032	hsa-miR-548aj	CLIP-seq
MIRT1168033	hsa-miR-548al	CLIP-seq
MIRT1168034	hsa-miR-548am	CLIP-seq
MIRT1168035	hsa-miR-548d-3p	CLIP-seq
MIRT1168036	hsa-miR-548e	CLIP-seq
MIRT1168037	hsa-miR-548f	CLIP-seq
MIRT1168038	hsa-miR-548p	CLIP-seq
MIRT1168039	hsa-miR-548s	CLIP-seq
MIRT1168040	hsa-miR-548x	CLIP-seq
MIRT1168041	hsa-miR-548z	CLIP-seq
MIRT1168042	hsa-miR-576-5p	CLIP-seq
MIRT1168043	hsa-miR-582-3p	CLIP-seq
MIRT1168044	hsa-miR-582-5p	CLIP-seq
MIRT1168045	hsa-miR-588	CLIP-seq
MIRT1168046	hsa-miR-600	CLIP-seq
MIRT1168047	hsa-miR-612	CLIP-seq
MIRT1168048	hsa-miR-625	CLIP-seq
MIRT1168049	hsa-miR-661	CLIP-seq
MIRT1168050	hsa-miR-892a	CLIP-seq
MIRT1168051	hsa-miR-944	CLIP-seq
MIRT1167991	hsa-miR-139-5p	CLIP-seq
MIRT2048437	hsa-miR-182	CLIP-seq
MIRT2048438	hsa-miR-203	CLIP-seq
MIRT1167993	hsa-miR-2114	CLIP-seq
MIRT2048439	hsa-miR-3165	CLIP-seq
MIRT1168001	hsa-miR-3613-3p	CLIP-seq
MIRT2048440	hsa-miR-3662	CLIP-seq
MIRT2048441	hsa-miR-3682-5p	CLIP-seq
MIRT1168012	hsa-miR-4291	CLIP-seq
MIRT2048442	hsa-miR-4470	CLIP-seq
MIRT2048443	hsa-miR-4803	CLIP-seq
MIRT2048444	hsa-miR-545	CLIP-seq
MIRT1168029	hsa-miR-548aa	CLIP-seq
MIRT1168030	hsa-miR-548ac	CLIP-seq
MIRT1168035	hsa-miR-548d-3p	CLIP-seq
MIRT1168038	hsa-miR-548p	CLIP-seq
MIRT1168041	hsa-miR-548z	CLIP-seq
MIRT2048445	hsa-miR-561	CLIP-seq
MIRT2277316	hsa-miR-1227	CLIP-seq
MIRT1167986	hsa-miR-1268	CLIP-seq
MIRT1167987	hsa-miR-1268b	CLIP-seq
MIRT2277317	hsa-miR-1273d	CLIP-seq
MIRT2277318	hsa-miR-1278	CLIP-seq
MIRT1167992	hsa-miR-144	CLIP-seq
MIRT1167997	hsa-miR-3148	CLIP-seq
MIRT2277319	hsa-miR-3179	CLIP-seq
MIRT2277320	hsa-miR-326	CLIP-seq
MIRT2277321	hsa-miR-330-5p	CLIP-seq
MIRT1168001	hsa-miR-3613-3p	CLIP-seq
MIRT1168002	hsa-miR-3622b-5p	CLIP-seq
MIRT2277322	hsa-miR-3664-3p	CLIP-seq
MIRT2277323	hsa-miR-3668	CLIP-seq
MIRT2048441	hsa-miR-3682-5p	CLIP-seq
MIRT2277324	hsa-miR-377	CLIP-seq
MIRT2277325	hsa-miR-3929	CLIP-seq
MIRT1168012	hsa-miR-4291	CLIP-seq
MIRT2277326	hsa-miR-4419b	CLIP-seq
MIRT2277327	hsa-miR-4433	CLIP-seq
MIRT2277328	hsa-miR-4459	CLIP-seq
MIRT2277329	hsa-miR-4478	CLIP-seq
MIRT2277330	hsa-miR-455-5p	CLIP-seq
MIRT1168020	hsa-miR-4668-5p	CLIP-seq
MIRT2277331	hsa-miR-4695-5p	CLIP-seq
MIRT2277332	hsa-miR-4724-5p	CLIP-seq
MIRT2277333	hsa-miR-4768-3p	CLIP-seq
MIRT2277334	hsa-miR-4768-5p	CLIP-seq
MIRT2277335	hsa-miR-4797-3p	CLIP-seq
MIRT2048443	hsa-miR-4803	CLIP-seq
MIRT2277336	hsa-miR-485-5p	CLIP-seq
MIRT2277337	hsa-miR-508-5p	CLIP-seq
MIRT2277338	hsa-miR-510	CLIP-seq
MIRT2277339	hsa-miR-512-5p	CLIP-seq
MIRT2277340	hsa-miR-518a-5p	CLIP-seq
MIRT2277341	hsa-miR-527	CLIP-seq
MIRT1168030	hsa-miR-548ac	CLIP-seq
MIRT1168035	hsa-miR-548d-3p	CLIP-seq
MIRT1168041	hsa-miR-548z	CLIP-seq
MIRT2277342	hsa-miR-550a	CLIP-seq
MIRT2048445	hsa-miR-561	CLIP-seq
MIRT2277343	hsa-miR-570	CLIP-seq
MIRT2277344	hsa-miR-596	CLIP-seq
MIRT1168048	hsa-miR-625	CLIP-seq
MIRT2277345	hsa-miR-802	CLIP-seq
MIRT2277346	hsa-miR-935	CLIP-seq
MIRT2277347	hsa-miR-942	CLIP-seq
MIRT1167986	hsa-miR-1268	CLIP-seq
MIRT1167987	hsa-miR-1268b	CLIP-seq
MIRT1168002	hsa-miR-3622b-5p	CLIP-seq
MIRT2277330	hsa-miR-455-5p	CLIP-seq
MIRT2391246	hsa-miR-499a-5p	CLIP-seq
MIRT2277338	hsa-miR-510	CLIP-seq
MIRT2391247	hsa-miR-511	CLIP-seq
MIRT2277339	hsa-miR-512-5p	CLIP-seq
MIRT1168030	hsa-miR-548ac	CLIP-seq
MIRT1168035	hsa-miR-548d-3p	CLIP-seq
MIRT1168041	hsa-miR-548z	CLIP-seq
MIRT2277342	hsa-miR-550a	CLIP-seq
MIRT2391248	hsa-miR-626	CLIP-seq
MIRT2277328	hsa-miR-4459	CLIP-seq
MIRT2454666	hsa-miR-4537	CLIP-seq
MIRT2277331	hsa-miR-4695-5p	CLIP-seq
MIRT2454667	hsa-miR-658	CLIP-seq
MIRT2454668	hsa-miR-665	CLIP-seq
MIRT2277328	hsa-miR-4459	CLIP-seq
MIRT2454666	hsa-miR-4537	CLIP-seq
MIRT2277331	hsa-miR-4695-5p	CLIP-seq
MIRT2454667	hsa-miR-658	CLIP-seq
MIRT2454668	hsa-miR-665	CLIP-seq
MIRT2576219	hsa-miR-1252	CLIP-seq
MIRT1167986	hsa-miR-1268	CLIP-seq
MIRT1167987	hsa-miR-1268b	CLIP-seq
MIRT1167989	hsa-miR-1285	CLIP-seq
MIRT2576220	hsa-miR-1827	CLIP-seq
MIRT2576221	hsa-miR-21	CLIP-seq
MIRT2576222	hsa-miR-219-2-3p	CLIP-seq
MIRT2576223	hsa-miR-3074-3p	CLIP-seq
MIRT1167999	hsa-miR-3187-5p	CLIP-seq
MIRT2576224	hsa-miR-338-3p	CLIP-seq
MIRT2576225	hsa-miR-34c-3p	CLIP-seq
MIRT1168001	hsa-miR-3613-3p	CLIP-seq
MIRT1168002	hsa-miR-3622b-5p	CLIP-seq
MIRT2277322	hsa-miR-3664-3p	CLIP-seq
MIRT2576226	hsa-miR-3672	CLIP-seq
MIRT1168006	hsa-miR-371-5p	CLIP-seq
MIRT1168007	hsa-miR-371b-5p	CLIP-seq
MIRT2576227	hsa-miR-375	CLIP-seq
MIRT2277325	hsa-miR-3929	CLIP-seq
MIRT2576228	hsa-miR-4293	CLIP-seq
MIRT2277326	hsa-miR-4419b	CLIP-seq
MIRT2277327	hsa-miR-4433	CLIP-seq
MIRT2277328	hsa-miR-4459	CLIP-seq
MIRT2277329	hsa-miR-4478	CLIP-seq
MIRT2576229	hsa-miR-4530	CLIP-seq
MIRT2454666	hsa-miR-4537	CLIP-seq
MIRT2277330	hsa-miR-455-5p	CLIP-seq
MIRT2576230	hsa-miR-4649-3p	CLIP-seq
MIRT2576231	hsa-miR-4662a-3p	CLIP-seq
MIRT2576232	hsa-miR-4666-5p	CLIP-seq
MIRT2576233	hsa-miR-4690-5p	CLIP-seq
MIRT2576234	hsa-miR-4694-3p	CLIP-seq
MIRT2277331	hsa-miR-4695-5p	CLIP-seq
MIRT1168022	hsa-miR-4711-3p	CLIP-seq
MIRT2576235	hsa-miR-4729	CLIP-seq
MIRT2277333	hsa-miR-4768-3p	CLIP-seq
MIRT2576236	hsa-miR-4773	CLIP-seq
MIRT2576237	hsa-miR-4775	CLIP-seq
MIRT2576238	hsa-miR-4786-5p	CLIP-seq
MIRT2576239	hsa-miR-4799-5p	CLIP-seq
MIRT2048443	hsa-miR-4803	CLIP-seq
MIRT2277336	hsa-miR-485-5p	CLIP-seq
MIRT2277337	hsa-miR-508-5p	CLIP-seq
MIRT2277338	hsa-miR-510	CLIP-seq
MIRT2277339	hsa-miR-512-5p	CLIP-seq
MIRT2576240	hsa-miR-522	CLIP-seq
MIRT2576241	hsa-miR-548a-5p	CLIP-seq
MIRT1168029	hsa-miR-548aa	CLIP-seq
MIRT2576242	hsa-miR-548ab	CLIP-seq
MIRT1168030	hsa-miR-548ac	CLIP-seq
MIRT2576243	hsa-miR-548ak	CLIP-seq
MIRT2576244	hsa-miR-548b-5p	CLIP-seq
MIRT2576245	hsa-miR-548c-5p	CLIP-seq
MIRT1168035	hsa-miR-548d-3p	CLIP-seq
MIRT2576246	hsa-miR-548d-5p	CLIP-seq
MIRT2576247	hsa-miR-548h	CLIP-seq
MIRT2576248	hsa-miR-548i	CLIP-seq
MIRT2576249	hsa-miR-548j	CLIP-seq
MIRT2576250	hsa-miR-548k	CLIP-seq
MIRT2576251	hsa-miR-548l	CLIP-seq
MIRT2576252	hsa-miR-548w	CLIP-seq
MIRT2576253	hsa-miR-548y	CLIP-seq
MIRT1168041	hsa-miR-548z	CLIP-seq
MIRT2277342	hsa-miR-550a	CLIP-seq
MIRT2576254	hsa-miR-559	CLIP-seq
MIRT2048445	hsa-miR-561	CLIP-seq
MIRT2576255	hsa-miR-590-5p	CLIP-seq
MIRT1168047	hsa-miR-612	CLIP-seq
MIRT2576256	hsa-miR-633	CLIP-seq
MIRT2576257	hsa-miR-657	CLIP-seq
MIRT2454667	hsa-miR-658	CLIP-seq
MIRT1168049	hsa-miR-661	CLIP-seq
MIRT2454668	hsa-miR-665	CLIP-seq
MIRT2576258	hsa-miR-766	CLIP-seq
MIRT2576259	hsa-miR-769-5p	CLIP-seq
MIRT1168050	hsa-miR-892a	CLIP-seq
MIRT1167986	hsa-miR-1268	CLIP-seq
MIRT1167987	hsa-miR-1268b	CLIP-seq
MIRT1167989	hsa-miR-1285	CLIP-seq
MIRT2576222	hsa-miR-219-2-3p	CLIP-seq
MIRT1167999	hsa-miR-3187-5p	CLIP-seq
MIRT2576224	hsa-miR-338-3p	CLIP-seq
MIRT1168001	hsa-miR-3613-3p	CLIP-seq
MIRT1168006	hsa-miR-371-5p	CLIP-seq
MIRT1168007	hsa-miR-371b-5p	CLIP-seq
MIRT2277328	hsa-miR-4459	CLIP-seq
MIRT2576229	hsa-miR-4530	CLIP-seq
MIRT2454666	hsa-miR-4537	CLIP-seq
MIRT2576233	hsa-miR-4690-5p	CLIP-seq
MIRT2277331	hsa-miR-4695-5p	CLIP-seq
MIRT1168022	hsa-miR-4711-3p	CLIP-seq
MIRT2277337	hsa-miR-508-5p	CLIP-seq
MIRT2277339	hsa-miR-512-5p	CLIP-seq
MIRT1168029	hsa-miR-548aa	CLIP-seq
MIRT1168030	hsa-miR-548ac	CLIP-seq
MIRT1168035	hsa-miR-548d-3p	CLIP-seq
MIRT1168041	hsa-miR-548z	CLIP-seq
MIRT2048445	hsa-miR-561	CLIP-seq
MIRT1168047	hsa-miR-612	CLIP-seq
MIRT2576256	hsa-miR-633	CLIP-seq
MIRT2576257	hsa-miR-657	CLIP-seq
MIRT2454667	hsa-miR-658	CLIP-seq
MIRT1168049	hsa-miR-661	CLIP-seq
MIRT2454668	hsa-miR-665	CLIP-seq
MIRT2576258	hsa-miR-766	CLIP-seq
MIRT1168050	hsa-miR-892a	CLIP-seq

Transcription factors

Show/Hide all(2)

Transcription factor	Regulation	Reference
HDAC9	Repression	10487760
MYOG	Activation	1656214

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003697	Function	Single-stranded DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003729	Function	MRNA binding	IBA	21873635
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	8455629
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0014902	Process	Myotube differentiation	IEP	8455629
GO:0030182	Process	Neuron differentiation	IEP	8455629
GO:0071014	Component	Post-mRNA release spliceosomal complex	IBA	21873635
GO:1990904	Component	Ribonucleoprotein complex	IBA	21873635
GO:2000815	Process	Regulation of mRNA stability involved in response to oxidative stress	IBA	21873635

MIM	HGNC	e!Ensembl
619395	17940	ENSG00000104177

Protein

UniProt ID

Q9P2K5

Protein name

Myelin expression factor 2 (MEF-2) (MyEF-2) (MST156)

Protein function

Transcriptional repressor of the myelin basic protein gene (MBP). Binds to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	102 → 172	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00076	RRM_1	235 → 304	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain
PF00076	RRM_1	525 → 593	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Sequence

MADANKAEVPGATGGDSPHLQPAEPPGEPRREPHPAEAEKQQPQHSSSSNGVKMENDESA
KEEKSDLKEKSTGSKKANRFHPYSKDKNSGAGEKKGPNRNRVFISNIPYDMKWQAIKDLM
REKVGEVTYVELFKDAEGKSRGCGVVEFKDEEFVKKALETMNKYDLSGRPLNIKEDPDGE
NARRALQRTGGSFPGGHVPDMGSGLMNLPPSILNNPNIPPEVISNLQAGRLGSTIFVANL
DFKVGWKKLKEVFSIAGTVKRADIKEDKDGKSRGMGTVTFEQAIEAVQAISMFNGQFLFD
RPMHVKMDDKSVPHEEYRSHDGKTPQLPRGLGGIGMGLGPGGQPISASQLNIGGVMGNLG
PGGMGMDGPGFGGMNRIGGGIGFGGLEAMNSMGGFGGVGRMGELYRGAMTSSMERDFGRG
DIGINQGFGDSFGRLGSAMIGGFAGRIGSSNMGPVGSGISGGMGSMNSVTGGMGMGLDRM
SSSFDRMGPGIGAILERSIDMDRGFLSGPMGSGMRERIGSKGNQIFVRNLPFDLTWQKLK
EKFSQCGHVMFAEIKMENGKSKGCGTVRFDSPESAEKACRIMNGIKISGREIDVRLDRNA

Sequence length

600

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Oculocutaneous albinism	Oculocutaneous albinism type 6, ALBINISM, OCULOCUTANEOUS, TYPE VI	rs387906240, rs121918167, rs121918169, rs121918170, rs28940876, rs104894314, rs61754388, rs61753185, rs104894313, rs61754393, rs28940879, rs61753178, rs61753180, rs61754375, rs61754387 View all (55 more)

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Hepatocellular	Associate	36658471
Disease Resistance	Associate	37908128
Glioblastoma	Associate	37556355
Leukemia Lymphoma Adult T Cell	Associate	35449091
Neoplasms	Associate	36658471, 37556355

MYEF2 (myelin expression factor 2)