MINK1 (misshapen like kinase 1)

Gene

• Entrez ID: 50488
• Gene name: Misshapen like kinase 1
• Gene symbol: MINK1
• Synonyms (NCBI Gene): B55, MAP4K6, MEKKK 6, MINK, YSK2, ZC3
• Chromosome: 17
• Chromosome location: 17p13.2
• Summary: This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK famil

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT049099	hsa-miR-92a-3p	CLASH	23622248
MIRT046617	hsa-miR-222-3p	CLASH	23622248
MIRT045281	hsa-miR-186-5p	CLASH	23622248
MIRT040973	hsa-miR-18a-3p	CLASH	23622248
MIRT037477	hsa-miR-744-5p	CLASH	23622248
MIRT036771	hsa-miR-760	CLASH	23622248
MIRT036060	hsa-miR-1301-3p	CLASH	23622248
MIRT077838	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT077845	hsa-miR-520f-3p	HITS-CLIP	23313552
MIRT077836	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT077844	hsa-miR-520e	HITS-CLIP	23313552
MIRT077839	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT077857	hsa-miR-302e	HITS-CLIP	23313552
MIRT077840	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT077841	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT077837	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT077847	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT077850	hsa-miR-520b	HITS-CLIP	23313552
MIRT077853	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT077838	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT077851	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT077848	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT077830	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT077832	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT077833	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT077831	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT077842	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT077852	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT077835	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT077860	hsa-miR-3662	HITS-CLIP	23313552
MIRT701968	hsa-miR-3609	HITS-CLIP	23313552
MIRT701967	hsa-miR-548ah-5p	HITS-CLIP	23313552
MIRT701966	hsa-miR-4796-3p	HITS-CLIP	23313552
MIRT077859	hsa-miR-3646	HITS-CLIP	23313552
MIRT146704	hsa-miR-6783-5p	HITS-CLIP	23313552
MIRT701965	hsa-miR-3185	HITS-CLIP	23313552
MIRT146657	hsa-miR-3179	HITS-CLIP	23313552
MIRT146636	hsa-miR-15b-3p	HITS-CLIP	23313552
MIRT701964	hsa-miR-3160-5p	HITS-CLIP	23313552
MIRT146661	hsa-miR-3202	HITS-CLIP	23313552
MIRT146689	hsa-miR-4747-5p	HITS-CLIP	23313552
MIRT146696	hsa-miR-5196-5p	HITS-CLIP	23313552
MIRT146648	hsa-miR-625-5p	HITS-CLIP	23313552
MIRT701963	hsa-miR-4525	HITS-CLIP	23313552
MIRT701962	hsa-miR-5010-5p	HITS-CLIP	23313552
MIRT146703	hsa-miR-6740-5p	HITS-CLIP	23313552
MIRT146654	hsa-miR-1275	HITS-CLIP	23313552
MIRT146684	hsa-miR-4665-5p	HITS-CLIP	23313552
MIRT146714	hsa-miR-7109-5p	HITS-CLIP	23313552
MIRT701961	hsa-miR-6751-5p	HITS-CLIP	23313552
MIRT701960	hsa-miR-6803-5p	HITS-CLIP	23313552
MIRT701959	hsa-miR-3942-3p	HITS-CLIP	23313552
MIRT701958	hsa-miR-450a-2-3p	HITS-CLIP	23313552
MIRT701957	hsa-miR-4260	HITS-CLIP	23313552
MIRT701956	hsa-miR-5572	HITS-CLIP	23313552
MIRT473215	hsa-miR-583	PAR-CLIP	20371350
MIRT493193	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT473208	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT473207	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT493192	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT493190	hsa-miR-1538	PAR-CLIP	20371350
MIRT493191	hsa-miR-4745-3p	PAR-CLIP	20371350
MIRT473206	hsa-miR-3153	PAR-CLIP	20371350
MIRT473205	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT473203	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT146673	hsa-miR-3180	PAR-CLIP	20371350
MIRT146658	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT146659	hsa-miR-3196	PAR-CLIP	20371350
MIRT146706	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT473215	hsa-miR-583	PAR-CLIP	23592263
MIRT146704	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT493193	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT473208	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT473207	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT493192	hsa-miR-671-5p	PAR-CLIP	23592263
MIRT493190	hsa-miR-1538	PAR-CLIP	23592263
MIRT493191	hsa-miR-4745-3p	PAR-CLIP	23592263
MIRT473206	hsa-miR-3153	PAR-CLIP	23592263
MIRT473205	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT473203	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT146673	hsa-miR-3180	PAR-CLIP	23592263
MIRT146658	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT146659	hsa-miR-3196	PAR-CLIP	23592263
MIRT146706	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT473215	hsa-miR-583	PAR-CLIP	23592263
MIRT473214	hsa-miR-1321	PAR-CLIP	23592263
MIRT473212	hsa-miR-4739	PAR-CLIP	23592263
MIRT473213	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT473211	hsa-miR-4270	PAR-CLIP	23592263
MIRT473210	hsa-miR-4441	PAR-CLIP	23592263
MIRT473209	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT473208	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT473207	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT473206	hsa-miR-3153	PAR-CLIP	23592263
MIRT473205	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT473203	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT473204	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT473202	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT473201	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT473200	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT146673	hsa-miR-3180	PAR-CLIP	23592263
MIRT146658	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT146659	hsa-miR-3196	PAR-CLIP	23592263
MIRT146706	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT077835	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT077831	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440240	hsa-miR-487b-3p	HITS-CLIP	24374217
MIRT077835	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT077781	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT077784	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT077782	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT077785	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT077830	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT077842	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT077832	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT077852	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT077831	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440240	hsa-miR-487b-3p	HITS-CLIP	24374217
MIRT077781	hsa-miR-15a-5p	PAR-CLIP	27292025
MIRT077784	hsa-miR-15b-5p	PAR-CLIP	27292025
MIRT077782	hsa-miR-16-5p	PAR-CLIP	27292025
MIRT077785	hsa-miR-195-5p	PAR-CLIP	27292025
MIRT077838	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT077845	hsa-miR-520f-3p	HITS-CLIP	23313552
MIRT077836	hsa-miR-302a-3p	HITS-CLIP	23313552
MIRT077844	hsa-miR-520e	HITS-CLIP	23313552
MIRT077839	hsa-miR-302d-3p	HITS-CLIP	23313552
MIRT077857	hsa-miR-302e	HITS-CLIP	23313552
MIRT077840	hsa-miR-372-3p	HITS-CLIP	23313552
MIRT077841	hsa-miR-373-3p	HITS-CLIP	23313552
MIRT077837	hsa-miR-302b-3p	HITS-CLIP	23313552
MIRT077847	hsa-miR-520a-3p	HITS-CLIP	23313552
MIRT077850	hsa-miR-520b	HITS-CLIP	23313552
MIRT077853	hsa-miR-520d-3p	HITS-CLIP	23313552
MIRT077838	hsa-miR-302c-3p	HITS-CLIP	23313552
MIRT077851	hsa-miR-520c-3p	HITS-CLIP	23313552
MIRT077848	hsa-miR-526b-3p	HITS-CLIP	23313552
MIRT077830	hsa-miR-17-5p	HITS-CLIP	23313552
MIRT077832	hsa-miR-93-5p	HITS-CLIP	23313552
MIRT077833	hsa-miR-106a-5p	HITS-CLIP	23313552
MIRT077831	hsa-miR-20a-5p	HITS-CLIP	23313552
MIRT077842	hsa-miR-20b-5p	HITS-CLIP	23313552
MIRT077852	hsa-miR-519d-3p	HITS-CLIP	23313552
MIRT077835	hsa-miR-106b-5p	HITS-CLIP	23313552
MIRT077860	hsa-miR-3662	HITS-CLIP	23313552
MIRT701968	hsa-miR-3609	HITS-CLIP	23313552
MIRT701967	hsa-miR-548ah-5p	HITS-CLIP	23313552
MIRT701966	hsa-miR-4796-3p	HITS-CLIP	23313552
MIRT077859	hsa-miR-3646	HITS-CLIP	23313552
MIRT146704	hsa-miR-6783-5p	HITS-CLIP	23313552
MIRT701965	hsa-miR-3185	HITS-CLIP	23313552
MIRT146657	hsa-miR-3179	HITS-CLIP	23313552
MIRT146636	hsa-miR-15b-3p	HITS-CLIP	23313552
MIRT701964	hsa-miR-3160-5p	HITS-CLIP	23313552
MIRT146661	hsa-miR-3202	HITS-CLIP	23313552
MIRT146689	hsa-miR-4747-5p	HITS-CLIP	23313552
MIRT146696	hsa-miR-5196-5p	HITS-CLIP	23313552
MIRT146648	hsa-miR-625-5p	HITS-CLIP	23313552
MIRT701963	hsa-miR-4525	HITS-CLIP	23313552
MIRT701962	hsa-miR-5010-5p	HITS-CLIP	23313552
MIRT146703	hsa-miR-6740-5p	HITS-CLIP	23313552
MIRT146654	hsa-miR-1275	HITS-CLIP	23313552
MIRT146684	hsa-miR-4665-5p	HITS-CLIP	23313552
MIRT146714	hsa-miR-7109-5p	HITS-CLIP	23313552
MIRT701961	hsa-miR-6751-5p	HITS-CLIP	23313552
MIRT701960	hsa-miR-6803-5p	HITS-CLIP	23313552
MIRT701959	hsa-miR-3942-3p	HITS-CLIP	23313552
MIRT701958	hsa-miR-450a-2-3p	HITS-CLIP	23313552
MIRT701957	hsa-miR-4260	HITS-CLIP	23313552
MIRT701956	hsa-miR-5572	HITS-CLIP	23313552
MIRT473215	hsa-miR-583	PAR-CLIP	20371350
MIRT493193	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT473208	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT473207	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT493192	hsa-miR-671-5p	PAR-CLIP	20371350
MIRT493190	hsa-miR-1538	PAR-CLIP	20371350
MIRT493191	hsa-miR-4745-3p	PAR-CLIP	20371350
MIRT473206	hsa-miR-3153	PAR-CLIP	20371350
MIRT473205	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT473203	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT146673	hsa-miR-3180	PAR-CLIP	20371350
MIRT146658	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT146659	hsa-miR-3196	PAR-CLIP	20371350
MIRT146706	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT473215	hsa-miR-583	PAR-CLIP	23592263
MIRT146704	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT493193	hsa-miR-1247-3p	PAR-CLIP	23592263
MIRT473208	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT473207	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT493192	hsa-miR-671-5p	PAR-CLIP	23592263
MIRT493190	hsa-miR-1538	PAR-CLIP	23592263
MIRT493191	hsa-miR-4745-3p	PAR-CLIP	23592263
MIRT473206	hsa-miR-3153	PAR-CLIP	23592263
MIRT473205	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT473203	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT146673	hsa-miR-3180	PAR-CLIP	23592263
MIRT146658	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT146659	hsa-miR-3196	PAR-CLIP	23592263
MIRT146706	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT473215	hsa-miR-583	PAR-CLIP	23592263
MIRT473214	hsa-miR-1321	PAR-CLIP	23592263
MIRT473212	hsa-miR-4739	PAR-CLIP	23592263
MIRT473213	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT473211	hsa-miR-4270	PAR-CLIP	23592263
MIRT473210	hsa-miR-4441	PAR-CLIP	23592263
MIRT473209	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT473208	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT473207	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT473206	hsa-miR-3153	PAR-CLIP	23592263
MIRT473205	hsa-miR-6733-5p	PAR-CLIP	23592263
MIRT473203	hsa-miR-6739-5p	PAR-CLIP	23592263
MIRT473204	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT473202	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT473201	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT473200	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT146673	hsa-miR-3180	PAR-CLIP	23592263
MIRT146658	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT146659	hsa-miR-3196	PAR-CLIP	23592263
MIRT146706	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT1149217	hsa-miR-106a	CLIP-seq
MIRT1149218	hsa-miR-106b	CLIP-seq
MIRT1149219	hsa-miR-1182	CLIP-seq
MIRT1149220	hsa-miR-1193	CLIP-seq
MIRT1149221	hsa-miR-1224-5p	CLIP-seq
MIRT1149222	hsa-miR-136	CLIP-seq
MIRT1149223	hsa-miR-15a	CLIP-seq
MIRT1149224	hsa-miR-15b	CLIP-seq
MIRT1149225	hsa-miR-16	CLIP-seq
MIRT1149226	hsa-miR-17	CLIP-seq
MIRT1149227	hsa-miR-181a	CLIP-seq
MIRT1149228	hsa-miR-181b	CLIP-seq
MIRT1149229	hsa-miR-181c	CLIP-seq
MIRT1149230	hsa-miR-181d	CLIP-seq
MIRT1149231	hsa-miR-1825	CLIP-seq
MIRT1149232	hsa-miR-1908	CLIP-seq
MIRT1149233	hsa-miR-1915	CLIP-seq
MIRT1149234	hsa-miR-195	CLIP-seq
MIRT1149235	hsa-miR-199a-5p	CLIP-seq
MIRT1149236	hsa-miR-199b-5p	CLIP-seq
MIRT1149237	hsa-miR-19a	CLIP-seq
MIRT1149238	hsa-miR-19b	CLIP-seq
MIRT1149239	hsa-miR-20a	CLIP-seq
MIRT1149240	hsa-miR-20b	CLIP-seq
MIRT1149241	hsa-miR-2110	CLIP-seq
MIRT1149242	hsa-miR-214	CLIP-seq
MIRT1149243	hsa-miR-2392	CLIP-seq
MIRT1149244	hsa-miR-302a	CLIP-seq
MIRT1149245	hsa-miR-302b	CLIP-seq
MIRT1149246	hsa-miR-302c	CLIP-seq
MIRT1149247	hsa-miR-302d	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT1149249	hsa-miR-3144-5p	CLIP-seq
MIRT1149250	hsa-miR-3147	CLIP-seq
MIRT1149251	hsa-miR-3150a-3p	CLIP-seq
MIRT1149252	hsa-miR-3155	CLIP-seq
MIRT1149253	hsa-miR-3155b	CLIP-seq
MIRT1149254	hsa-miR-3191	CLIP-seq
MIRT1149255	hsa-miR-320e	CLIP-seq
MIRT1149256	hsa-miR-331-3p	CLIP-seq
MIRT1149257	hsa-miR-3605-5p	CLIP-seq
MIRT1149258	hsa-miR-372	CLIP-seq
MIRT1149259	hsa-miR-373	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149261	hsa-miR-3915	CLIP-seq
MIRT1149262	hsa-miR-3918	CLIP-seq
MIRT1149263	hsa-miR-3922-5p	CLIP-seq
MIRT1149264	hsa-miR-3925-3p	CLIP-seq
MIRT1149265	hsa-miR-3936	CLIP-seq
MIRT1149266	hsa-miR-3938	CLIP-seq
MIRT1149267	hsa-miR-424	CLIP-seq
MIRT1149268	hsa-miR-4254	CLIP-seq
MIRT1149269	hsa-miR-4257	CLIP-seq
MIRT1149270	hsa-miR-4262	CLIP-seq
MIRT1149271	hsa-miR-4269	CLIP-seq
MIRT1149272	hsa-miR-4271	CLIP-seq
MIRT1149273	hsa-miR-4292	CLIP-seq
MIRT1149274	hsa-miR-4308	CLIP-seq
MIRT1149275	hsa-miR-4323	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT1149277	hsa-miR-4422	CLIP-seq
MIRT1149278	hsa-miR-4425	CLIP-seq
MIRT1149279	hsa-miR-4490	CLIP-seq
MIRT1149280	hsa-miR-4530	CLIP-seq
MIRT1149281	hsa-miR-4652-5p	CLIP-seq
MIRT1149282	hsa-miR-4653-3p	CLIP-seq
MIRT1149283	hsa-miR-4667-5p	CLIP-seq
MIRT1149284	hsa-miR-4685-5p	CLIP-seq
MIRT1149285	hsa-miR-4689	CLIP-seq
MIRT1149286	hsa-miR-4690-5p	CLIP-seq
MIRT1149287	hsa-miR-4700-5p	CLIP-seq
MIRT1149288	hsa-miR-4711-5p	CLIP-seq
MIRT1149289	hsa-miR-4717-5p	CLIP-seq
MIRT1149290	hsa-miR-4723-5p	CLIP-seq
MIRT1149291	hsa-miR-4725-3p	CLIP-seq
MIRT1149292	hsa-miR-4731-5p	CLIP-seq
MIRT1149293	hsa-miR-4732-3p	CLIP-seq
MIRT1149294	hsa-miR-4753-5p	CLIP-seq
MIRT1149295	hsa-miR-4774-5p	CLIP-seq
MIRT1149296	hsa-miR-4781-3p	CLIP-seq
MIRT1149297	hsa-miR-484	CLIP-seq
MIRT1149298	hsa-miR-497	CLIP-seq
MIRT1149299	hsa-miR-498	CLIP-seq
MIRT1149300	hsa-miR-519d	CLIP-seq
MIRT1149301	hsa-miR-520f	CLIP-seq
MIRT1149302	hsa-miR-548ah	CLIP-seq
MIRT1149303	hsa-miR-555	CLIP-seq
MIRT1149304	hsa-miR-615-5p	CLIP-seq
MIRT1149305	hsa-miR-625	CLIP-seq
MIRT1149306	hsa-miR-663	CLIP-seq
MIRT1149307	hsa-miR-670	CLIP-seq
MIRT1149308	hsa-miR-93	CLIP-seq
MIRT1149309	hsa-miR-939	CLIP-seq
MIRT1149301	hsa-miR-520f	CLIP-seq
MIRT1149305	hsa-miR-625	CLIP-seq
MIRT2042455	hsa-miR-1	CLIP-seq
MIRT2042456	hsa-miR-105	CLIP-seq
MIRT1149219	hsa-miR-1182	CLIP-seq
MIRT1149220	hsa-miR-1193	CLIP-seq
MIRT2042457	hsa-miR-1268	CLIP-seq
MIRT2042458	hsa-miR-1268b	CLIP-seq
MIRT2042459	hsa-miR-1343	CLIP-seq
MIRT2042460	hsa-miR-1470	CLIP-seq
MIRT1149223	hsa-miR-15a	CLIP-seq
MIRT1149224	hsa-miR-15b	CLIP-seq
MIRT1149225	hsa-miR-16	CLIP-seq
MIRT1149227	hsa-miR-181a	CLIP-seq
MIRT1149228	hsa-miR-181b	CLIP-seq
MIRT1149229	hsa-miR-181c	CLIP-seq
MIRT1149230	hsa-miR-181d	CLIP-seq
MIRT1149231	hsa-miR-1825	CLIP-seq
MIRT2042461	hsa-miR-185	CLIP-seq
MIRT1149233	hsa-miR-1915	CLIP-seq
MIRT1149234	hsa-miR-195	CLIP-seq
MIRT1149235	hsa-miR-199a-5p	CLIP-seq
MIRT1149236	hsa-miR-199b-5p	CLIP-seq
MIRT1149237	hsa-miR-19a	CLIP-seq
MIRT1149238	hsa-miR-19b	CLIP-seq
MIRT2042462	hsa-miR-2052	CLIP-seq
MIRT2042463	hsa-miR-206	CLIP-seq
MIRT1149241	hsa-miR-2110	CLIP-seq
MIRT1149242	hsa-miR-214	CLIP-seq
MIRT2042464	hsa-miR-219-2-3p	CLIP-seq
MIRT1149243	hsa-miR-2392	CLIP-seq
MIRT2042465	hsa-miR-2964a-3p	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT1149249	hsa-miR-3144-5p	CLIP-seq
MIRT1149250	hsa-miR-3147	CLIP-seq
MIRT1149251	hsa-miR-3150a-3p	CLIP-seq
MIRT1149252	hsa-miR-3155	CLIP-seq
MIRT1149253	hsa-miR-3155b	CLIP-seq
MIRT2042466	hsa-miR-3183	CLIP-seq
MIRT1149254	hsa-miR-3191	CLIP-seq
MIRT1149255	hsa-miR-320e	CLIP-seq
MIRT1149256	hsa-miR-331-3p	CLIP-seq
MIRT1149257	hsa-miR-3605-5p	CLIP-seq
MIRT2042467	hsa-miR-3616-3p	CLIP-seq
MIRT2042468	hsa-miR-371-5p	CLIP-seq
MIRT2042469	hsa-miR-371b-5p	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149263	hsa-miR-3922-5p	CLIP-seq
MIRT1149264	hsa-miR-3925-3p	CLIP-seq
MIRT1149265	hsa-miR-3936	CLIP-seq
MIRT1149267	hsa-miR-424	CLIP-seq
MIRT1149268	hsa-miR-4254	CLIP-seq
MIRT1149269	hsa-miR-4257	CLIP-seq
MIRT1149270	hsa-miR-4262	CLIP-seq
MIRT1149271	hsa-miR-4269	CLIP-seq
MIRT1149272	hsa-miR-4271	CLIP-seq
MIRT2042470	hsa-miR-4279	CLIP-seq
MIRT2042471	hsa-miR-4306	CLIP-seq
MIRT2042472	hsa-miR-4307	CLIP-seq
MIRT1149274	hsa-miR-4308	CLIP-seq
MIRT1149275	hsa-miR-4323	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT1149277	hsa-miR-4422	CLIP-seq
MIRT1149278	hsa-miR-4425	CLIP-seq
MIRT2042473	hsa-miR-4452	CLIP-seq
MIRT2042474	hsa-miR-4469	CLIP-seq
MIRT2042475	hsa-miR-4477a	CLIP-seq
MIRT2042476	hsa-miR-4487	CLIP-seq
MIRT1149279	hsa-miR-4490	CLIP-seq
MIRT1149280	hsa-miR-4530	CLIP-seq
MIRT2042477	hsa-miR-4639-3p	CLIP-seq
MIRT2042478	hsa-miR-4644	CLIP-seq
MIRT2042479	hsa-miR-4646-5p	CLIP-seq
MIRT1149281	hsa-miR-4652-5p	CLIP-seq
MIRT1149282	hsa-miR-4653-3p	CLIP-seq
MIRT2042480	hsa-miR-4667-3p	CLIP-seq
MIRT1149283	hsa-miR-4667-5p	CLIP-seq
MIRT1149286	hsa-miR-4690-5p	CLIP-seq
MIRT2042481	hsa-miR-4693-3p	CLIP-seq
MIRT2042482	hsa-miR-4694-3p	CLIP-seq
MIRT1149287	hsa-miR-4700-5p	CLIP-seq
MIRT1149288	hsa-miR-4711-5p	CLIP-seq
MIRT1149289	hsa-miR-4717-5p	CLIP-seq
MIRT2042483	hsa-miR-4721	CLIP-seq
MIRT2042484	hsa-miR-4723-3p	CLIP-seq
MIRT1149290	hsa-miR-4723-5p	CLIP-seq
MIRT1149291	hsa-miR-4725-3p	CLIP-seq
MIRT1149292	hsa-miR-4731-5p	CLIP-seq
MIRT1149293	hsa-miR-4732-3p	CLIP-seq
MIRT2042485	hsa-miR-4747-3p	CLIP-seq
MIRT1149294	hsa-miR-4753-5p	CLIP-seq
MIRT1149295	hsa-miR-4774-5p	CLIP-seq
MIRT1149296	hsa-miR-4781-3p	CLIP-seq
MIRT1149297	hsa-miR-484	CLIP-seq
MIRT2042486	hsa-miR-495	CLIP-seq
MIRT1149298	hsa-miR-497	CLIP-seq
MIRT1149299	hsa-miR-498	CLIP-seq
MIRT2042487	hsa-miR-511	CLIP-seq
MIRT2042488	hsa-miR-548p	CLIP-seq
MIRT1149303	hsa-miR-555	CLIP-seq
MIRT2042489	hsa-miR-563	CLIP-seq
MIRT2042490	hsa-miR-613	CLIP-seq
MIRT1149304	hsa-miR-615-5p	CLIP-seq
MIRT1149305	hsa-miR-625	CLIP-seq
MIRT1149309	hsa-miR-939	CLIP-seq
MIRT1149220	hsa-miR-1193	CLIP-seq
MIRT1149231	hsa-miR-1825	CLIP-seq
MIRT1149235	hsa-miR-199a-5p	CLIP-seq
MIRT1149236	hsa-miR-199b-5p	CLIP-seq
MIRT1149241	hsa-miR-2110	CLIP-seq
MIRT1149242	hsa-miR-214	CLIP-seq
MIRT1149243	hsa-miR-2392	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT1149250	hsa-miR-3147	CLIP-seq
MIRT1149251	hsa-miR-3150a-3p	CLIP-seq
MIRT2272081	hsa-miR-3150b-3p	CLIP-seq
MIRT1149252	hsa-miR-3155	CLIP-seq
MIRT1149253	hsa-miR-3155b	CLIP-seq
MIRT1149257	hsa-miR-3605-5p	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149264	hsa-miR-3925-3p	CLIP-seq
MIRT1149269	hsa-miR-4257	CLIP-seq
MIRT1149272	hsa-miR-4271	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT2272082	hsa-miR-4419a	CLIP-seq
MIRT1149277	hsa-miR-4422	CLIP-seq
MIRT1149278	hsa-miR-4425	CLIP-seq
MIRT2272083	hsa-miR-4447	CLIP-seq
MIRT2272084	hsa-miR-4472	CLIP-seq
MIRT2272085	hsa-miR-4510	CLIP-seq
MIRT1149280	hsa-miR-4530	CLIP-seq
MIRT2272086	hsa-miR-4651	CLIP-seq
MIRT1149285	hsa-miR-4689	CLIP-seq
MIRT1149286	hsa-miR-4690-5p	CLIP-seq
MIRT1149288	hsa-miR-4711-5p	CLIP-seq
MIRT1149290	hsa-miR-4723-5p	CLIP-seq
MIRT1149291	hsa-miR-4725-3p	CLIP-seq
MIRT2272087	hsa-miR-4779	CLIP-seq
MIRT1149296	hsa-miR-4781-3p	CLIP-seq
MIRT2272088	hsa-miR-4784	CLIP-seq
MIRT1149297	hsa-miR-484	CLIP-seq
MIRT2272089	hsa-miR-608	CLIP-seq
MIRT2272090	hsa-miR-1302	CLIP-seq
MIRT1149231	hsa-miR-1825	CLIP-seq
MIRT1149233	hsa-miR-1915	CLIP-seq
MIRT1149235	hsa-miR-199a-5p	CLIP-seq
MIRT1149236	hsa-miR-199b-5p	CLIP-seq
MIRT1149255	hsa-miR-320e	CLIP-seq
MIRT1149262	hsa-miR-3918	CLIP-seq
MIRT1149268	hsa-miR-4254	CLIP-seq
MIRT2272091	hsa-miR-4298	CLIP-seq
MIRT1149290	hsa-miR-4723-5p	CLIP-seq
MIRT2272092	hsa-miR-548c-3p	CLIP-seq
MIRT1149304	hsa-miR-615-5p	CLIP-seq
MIRT2272093	hsa-miR-647	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT2272081	hsa-miR-3150b-3p	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT2272088	hsa-miR-4784	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT1149250	hsa-miR-3147	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT1149278	hsa-miR-4425	CLIP-seq
MIRT1149296	hsa-miR-4781-3p	CLIP-seq
MIRT2042456	hsa-miR-105	CLIP-seq
MIRT2042468	hsa-miR-371-5p	CLIP-seq
MIRT2042469	hsa-miR-371b-5p	CLIP-seq
MIRT2465639	hsa-miR-4434	CLIP-seq
MIRT2465640	hsa-miR-4516	CLIP-seq
MIRT2465641	hsa-miR-4531	CLIP-seq
MIRT2042482	hsa-miR-4694-3p	CLIP-seq
MIRT1149290	hsa-miR-4723-5p	CLIP-seq
MIRT1149220	hsa-miR-1193	CLIP-seq
MIRT2042457	hsa-miR-1268	CLIP-seq
MIRT2042458	hsa-miR-1268b	CLIP-seq
MIRT1149231	hsa-miR-1825	CLIP-seq
MIRT2042461	hsa-miR-185	CLIP-seq
MIRT1149235	hsa-miR-199a-5p	CLIP-seq
MIRT1149236	hsa-miR-199b-5p	CLIP-seq
MIRT1149241	hsa-miR-2110	CLIP-seq
MIRT1149242	hsa-miR-214	CLIP-seq
MIRT1149243	hsa-miR-2392	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT1149250	hsa-miR-3147	CLIP-seq
MIRT1149251	hsa-miR-3150a-3p	CLIP-seq
MIRT1149252	hsa-miR-3155	CLIP-seq
MIRT1149253	hsa-miR-3155b	CLIP-seq
MIRT1149257	hsa-miR-3605-5p	CLIP-seq
MIRT2042467	hsa-miR-3616-3p	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149264	hsa-miR-3925-3p	CLIP-seq
MIRT1149269	hsa-miR-4257	CLIP-seq
MIRT1149272	hsa-miR-4271	CLIP-seq
MIRT2042471	hsa-miR-4306	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT1149277	hsa-miR-4422	CLIP-seq
MIRT1149278	hsa-miR-4425	CLIP-seq
MIRT1149280	hsa-miR-4530	CLIP-seq
MIRT2042478	hsa-miR-4644	CLIP-seq
MIRT1149286	hsa-miR-4690-5p	CLIP-seq
MIRT2042481	hsa-miR-4693-3p	CLIP-seq
MIRT1149288	hsa-miR-4711-5p	CLIP-seq
MIRT2042483	hsa-miR-4721	CLIP-seq
MIRT1149291	hsa-miR-4725-3p	CLIP-seq
MIRT1149296	hsa-miR-4781-3p	CLIP-seq
MIRT1149297	hsa-miR-484	CLIP-seq
MIRT1149220	hsa-miR-1193	CLIP-seq
MIRT2042457	hsa-miR-1268	CLIP-seq
MIRT2042458	hsa-miR-1268b	CLIP-seq
MIRT2042461	hsa-miR-185	CLIP-seq
MIRT1149241	hsa-miR-2110	CLIP-seq
MIRT1149243	hsa-miR-2392	CLIP-seq
MIRT1149248	hsa-miR-3122	CLIP-seq
MIRT1149250	hsa-miR-3147	CLIP-seq
MIRT1149251	hsa-miR-3150a-3p	CLIP-seq
MIRT1149257	hsa-miR-3605-5p	CLIP-seq
MIRT2042467	hsa-miR-3616-3p	CLIP-seq
MIRT1149260	hsa-miR-3913-5p	CLIP-seq
MIRT1149272	hsa-miR-4271	CLIP-seq
MIRT2042471	hsa-miR-4306	CLIP-seq
MIRT1149276	hsa-miR-4328	CLIP-seq
MIRT1149278	hsa-miR-4425	CLIP-seq
MIRT2042478	hsa-miR-4644	CLIP-seq
MIRT2042481	hsa-miR-4693-3p	CLIP-seq
MIRT2042483	hsa-miR-4721	CLIP-seq
MIRT1149291	hsa-miR-4725-3p	CLIP-seq
MIRT1149296	hsa-miR-4781-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IBA
GO:0000166	Function	Nucleotide binding	IEA
GO:0001952	Process	Regulation of cell-matrix adhesion	IMP	15469942
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	10708748
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	18930710, 21690388
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	15469942, 18930710, 25816751, 25852190, 26496226, 32707033, 33961781, 36931259
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	ISS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	18930710
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA	15469942
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006468	Process	Protein phosphorylation	IMP	21690388
GO:0006468	Process	Protein phosphorylation	ISS
GO:0007254	Process	JNK cascade	TAS	10708748
GO:0007268	Process	Chemical synaptic transmission	ISS
GO:0007420	Process	Brain development	ISS
GO:0014069	Component	Postsynaptic density	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0022407	Process	Regulation of cell-cell adhesion	IMP	15469942
GO:0030036	Process	Actin cytoskeleton organization	IBA
GO:0030036	Process	Actin cytoskeleton organization	IMP	15469942
GO:0030334	Process	Regulation of cell migration	IMP	15469942
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043408	Process	Regulation of MAPK cascade	IBA
GO:0045202	Component	Synapse	IEA
GO:0046328	Process	Regulation of JNK cascade	IEA
GO:0046330	Process	Positive regulation of JNK cascade	IMP	15469942
GO:0046330	Process	Positive regulation of JNK cascade	ISS
GO:0046777	Process	Protein autophosphorylation	IDA	15469942
GO:0048812	Process	Neuron projection morphogenesis	IBA
GO:0048813	Process	Dendrite morphogenesis	ISS
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1900745	Process	Positive regulation of p38MAPK cascade	ISS
GO:1902533	Process	Positive regulation of intracellular signal transduction	IEA
GO:2000311	Process	Regulation of AMPA receptor activity	ISS

Other IDs

• MIM: 609426
• HGNC: 17565
• e!Ensembl: ENSG00000141503

Protein

• UniProt ID: Q8N4C8
• Protein name: Misshapen-like kinase 1 (EC 2.7.11.1) (GCK family kinase MiNK) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (Mitogen-activated protein kinase kinase kinase kinase 6)
• Protein function: Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking (PubMed:10708748, PubMed:16337592). Required for normal synaptic density, den
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	25 → 289	Protein kinase domain	Domain
  PF00780	CNH	1023 → 1303	CNH domain	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal
• Sequence:

  MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
  DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNT
  KGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDR
  TVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAPPLCDMHPMR
  ALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLSRPPTEQLLKFPFIRDQPTERQVRI
  QLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHGEEGEPSSIMNVPGESTLRREFLRLQQ
  ENKSNSEALKQQQQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRK
  LQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQ
  QQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADKPAWAREVEERTRMNKQQNSPLAKS
  KPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQ
  SLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRP
  DNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPG
  PPAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLPQAGSLERNRVGVSSKPDSSPV
  LSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKKAMDYSSSSEEVESSEDDEEEG
  EGGPAEGSRDTPGGRSDGDTDSVSTMVVHDVEEITGTQPPYGGGTMVVQRTPEEERNLLH
  ADSNGYTNLPDVVQPSHSPTENSKGQSPPSKDGSGDYQSRGLVKAPGKSSFTMFVDLGIY
  QPGGSGDSIPITALVGGEGTRLDQLQYDVRKGSVVNVNPTNTRAHSETPEIRKYKKRFNS
  EILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQMDVLEGLNLLITISGKRN
  KLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDMEGCGHYRVVKYERIKFLVIALKSSVEV
  YAWAPKPYHKFMAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDI
  YIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAY
  ICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVY
  FMTLNRNCIMNW

• Sequence length: 1332

Pathways

Reactome:

Oxidative Stress Induced Senescence

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	rs2509187457	RCV004557803
See cases	Uncertain significance	rs1371779157	RCV005255503

Associations from Text Mining
Disease Name	Relationship Type	References
Alzheimer Disease	Associate	30413934
Autistic Disorder	Associate	36012658
Carcinoma Hepatocellular	Associate	33818013
Disease	Associate	36012658
Drug Related Side Effects and Adverse Reactions	Associate	19535438, 26085163
Epilepsy	Associate	36012658
Kidney Failure Chronic	Stimulate	35083784
Lupus Erythematosus Systemic	Associate	32620744
Neoplasms	Associate	26085163, 27184734
Osteoporosis	Associate	36012658