Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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5010
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Claudin 11 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
CLDN11 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
HLD22, OSP, OTM |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
HLD22 |
Chromosome
Chromosome number
|
3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
3q26.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellula |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Multiple sclerosis |
Multiple Sclerosis, Multiple Sclerosis, Acute Fulminating |
rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544 View all (4 more) |
25911099 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Leukodystrophy |
leukodystrophy, hypomyelinating, 22 |
|
|
GenCC |
Prostate cancer |
Prostate cancer |
Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population. |
|
GWAS, CBGDA |
Restless Legs Syndrome |
Restless Legs Syndrome |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Arrest of spermatogenesis |
Associate
|
20850723 |
Breast Neoplasms |
Associate
|
33714203, 33971623 |
Carcinogenesis |
Associate
|
19956721 |
Carcinoma Squamous Cell |
Associate
|
27234382, 27992079, 31551535 |
COVID 19 |
Inhibit
|
34436630 |
Dermatitis Allergic Contact |
Associate
|
31783056 |
Dysplastic Nevus Syndrome |
Associate
|
24999589 |
Ehlers Danlos syndrome type 3 |
Associate
|
27518164 |
Eye Abnormalities |
Associate
|
33313762 |
Focal Cortical Dysplasia |
Associate
|
34301297 |
Focal cortical dysplasia of Taylor |
Associate
|
34301297 |
Hyperopia |
Associate
|
33313762 |
Joint Instability |
Associate
|
27518164 |
Klinefelter Syndrome |
Associate
|
31739598 |
Lymphatic Metastasis |
Associate
|
28743857, 33441952 |
Melanoma |
Associate
|
24999589 |
Multiple Myeloma |
Associate
|
37014739 |
Multiple Sclerosis |
Associate
|
26768647 |
Nasopharyngeal Carcinoma |
Associate
|
29747653, 36354184 |
Neoplasm Metastasis |
Associate
|
28743857 |
Neoplasm Metastasis |
Inhibit
|
36354184 |
Neoplasms |
Stimulate
|
24268521 |
Neoplasms |
Associate
|
24999589, 27992079, 28743857, 29747653, 35048636 |
Pelizaeus Merzbacher like disease autosomal recessive 2 |
Associate
|
33313762, 37531724 |
Prostatic Neoplasms |
Associate
|
24497940 |
Schizophrenia |
Associate
|
17223013 |
Spastic Ataxia |
Associate
|
33313762 |
Speech Disorders |
Associate
|
33313762 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
28743857 |
Stomach Diseases |
Associate
|
28350854 |
Stomach Neoplasms |
Associate
|
19956721, 23919729, 33441952 |
Stomach Neoplasms |
Inhibit
|
28350854 |
|