Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	4988
Gene name Gene Name - the full gene name approved by the HGNC.	Opioid receptor mu 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	OPRM1
Synonyms (NCBI Gene) Gene synonyms aliases	LMOR, M-OR-1, MOP, MOR, MOR1, OPRM
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q25.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an importa

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SNP ID	Visualize variation	Clinical significance	Consequence
rs497332	C>A,G,T	Drug-response	Genic downstream transcript variant, intron variant
rs540825	A>C,G,T	Drug-response	Intron variant, synonymous variant, missense variant, genic downstream transcript variant, coding sequence variant
rs562859	C>A,G,T	Drug-response	Intron variant, synonymous variant, missense variant, genic downstream transcript variant, coding sequence variant
rs563649	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, genic downstream transcript variant
rs606545	G>A,C	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant, non coding transcript variant
rs623956	A>G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant, non coding transcript variant
rs650245	A>C,G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant
rs650825	G>A	Drug-response	Genic downstream transcript variant, intron variant
rs675026	A>C,G	Drug-response	Genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs677830	C>A,G,T	Drug-response, benign	Intron variant, missense variant, genic downstream transcript variant, stop gained, coding sequence variant
rs1799971	A>G	Drug-response, uncertain-significance	Intron variant, missense variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant
rs2075572	G>C	Drug-response	Genic downstream transcript variant, intron variant
rs6912029	G>T	Drug-response	5 prime UTR variant, intron variant, coding sequence variant, upstream transcript variant, missense variant, genic upstream transcript variant
rs9282821	A>C,T	Drug-response	Intron variant, genic downstream transcript variant
rs9322446	G>A	Drug-response	5 prime UTR variant, genic upstream transcript variant, intron variant, genic downstream transcript variant
rs9479757	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs11575858	C>T	Drug-response	3 prime UTR variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs17174794	C>G,T	Benign, drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, missense variant, coding sequence variant
rs17181192	T>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs41292890	C>T	Drug-response	Non coding transcript variant, genic upstream transcript variant, synonymous variant, intron variant, coding sequence variant, 5 prime UTR variant
rs60254893	C>G,T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs62638690	G>T	Drug-response	Non coding transcript variant, missense variant, genic downstream transcript variant, intron variant, coding sequence variant
rs71021021	TTTTTT>-,TTTTT,TTTTTTT,TTTTTTTTTT	Drug-response	Non coding transcript variant, downstream transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant
rs77696469	C>G,T	Drug-response	Non coding transcript variant, intron variant, 3 prime UTR variant, genic downstream transcript variant
rs78937301	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs113270588	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant
rs114492858	C>G,T	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, downstream transcript variant, genic downstream transcript variant
rs115788842	T>A	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant
rs139944762	C>A,T	Drug-response	Genic downstream transcript variant, 5 prime UTR variant, intron variant, genic upstream transcript variant
rs140560182	G>A	Drug-response	Genic downstream transcript variant, intron variant, downstream transcript variant
rs150821368	C>T	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant, downstream transcript variant
rs184553578	C>A,T	Drug-response	Missense variant, genic downstream transcript variant, non coding transcript variant, intron variant, coding sequence variant
rs186439043	C>T	Drug-response	Intron variant, coding sequence variant, missense variant, genic downstream transcript variant
rs199648369	C>G,T	Drug-response	Genic upstream transcript variant, coding sequence variant, 5 prime UTR variant, non coding transcript variant, intron variant, missense variant
rs199650905	C>T	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs199878364	C>T	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs199942335	G>A,C	Drug-response	Coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs200245799	G>A,C	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic downstream transcript variant
rs200512398	C>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, synonymous variant, stop gained, genic downstream transcript variant
rs200587105	G>A,C	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs200646591	G>A	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs200803187	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs200869983	C>T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, stop gained, genic downstream transcript variant
rs200915701	C>T	Drug-response	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, synonymous variant
rs201126701	G>A	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs201310502	C>G,T	Drug-response	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, missense variant
rs201518555	A>C,G	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs201750445	G>A,T	Drug-response	Intron variant, genic downstream transcript variant
rs201829386	C>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic downstream transcript variant
rs201858274	G>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, stop gained, missense variant, genic downstream transcript variant
rs370868117	C>T	Drug-response	Genic upstream transcript variant, coding sequence variant, 5 prime UTR variant, missense variant, non coding transcript variant, intron variant
rs377704466	G>A	Drug-response	Genic upstream transcript variant, intron variant
rs536957156	G>A,C	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs542615961	C>A,T	Drug-response	Non coding transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant, downstream transcript variant
rs546524303	G>A,T	Drug-response	Upstream transcript variant, genic upstream transcript variant, intron variant
rs552928147	A>C,G	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs557690438	A>G,T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs567300902	G>A	Drug-response	Non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, intron variant
rs571470402	A>C,G	Drug-response	Genic upstream transcript variant, intron variant, upstream transcript variant
rs573698787	C>T	Drug-response	Genic downstream transcript variant, intron variant, 3 prime UTR variant
rs577345039	C>G,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic upstream transcript variant
rs745863104	C>A,G,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic upstream transcript variant, synonymous variant
rs747345350	C>A,G	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs747772652	A>C,G	Drug-response	Intron variant, coding sequence variant, non coding transcript variant, missense variant, genic upstream transcript variant
rs749003633	C>T	Drug-response	Intron variant, stop gained, coding sequence variant, non coding transcript variant, genic downstream transcript variant
rs751081299	T>C,G	Drug-response	Intron variant, coding sequence variant, non coding transcript variant, missense variant, genic downstream transcript variant
rs765963522	C>T	Drug-response	Intron variant, coding sequence variant, synonymous variant, genic downstream transcript variant, non coding transcript variant
rs767783492	G>A,T	Drug-response	Genic downstream transcript variant, intron variant, coding sequence variant, missense variant
rs768115985	A>C	Drug-response	Genic downstream transcript variant, intron variant, stop lost, terminator codon variant
rs769540300	G>A	Drug-response	Intron variant, coding sequence variant, missense variant, genic downstream transcript variant, non coding transcript variant
rs769686797	G>A,C	Drug-response	Genic upstream transcript variant, intron variant
rs771278948	A>-,AA	Drug-response	Genic downstream transcript variant, intron variant
rs776184873	G>A	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant, genic upstream transcript variant
rs778238775	G>A,T	Drug-response	Non coding transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs778888827	T>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs898784845	A>G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant
rs914204741	C>G,T	Drug-response	Intron variant, genic downstream transcript variant
rs937431474	G>A,C	Drug-response	Genic downstream transcript variant, 5 prime UTR variant, intron variant, genic upstream transcript variant
rs947787494	C>A,G	Drug-response	Downstream transcript variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, intron variant
rs958018897	G>A	Drug-response	3 prime UTR variant, genic downstream transcript variant, intron variant, non coding transcript variant
rs968231224	C>T	Drug-response	3 prime UTR variant, genic downstream transcript variant, intron variant, non coding transcript variant
rs972892962	G>A	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant
rs979061434	C>G,T	Drug-response	Coding sequence variant, genic downstream transcript variant, missense variant, intron variant
rs984634670	G>A	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs986844324	C>G	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs994797893	C>T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, downstream transcript variant
rs1014331595	G>A,C,T	Drug-response	Genic downstream transcript variant, non coding transcript variant, intron variant, 3 prime UTR variant
rs1017227710	G>A	Drug-response	Genic downstream transcript variant, intron variant, 3 prime UTR variant
rs1033852015	A>G	Drug-response	Genic downstream transcript variant, genic upstream transcript variant, 5 prime UTR variant, intron variant
rs1160295304	C>T	Drug-response	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, missense variant, intron variant
rs1160455955	G>A	Drug-response	Genic downstream transcript variant, downstream transcript variant, intron variant
rs1169090293	A>G	Drug-response	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, intron variant, downstream transcript variant, synonymous variant
rs1178930557	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1183268180	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1190969003	C>T	Drug-response	Non coding transcript variant, synonymous variant, coding sequence variant, intron variant, genic upstream transcript variant
rs1201764699	C>T	Drug-response	Intron variant, 5 prime UTR variant, genic downstream transcript variant, genic upstream transcript variant
rs1210793358	A>G	Drug-response	Genic downstream transcript variant, coding sequence variant, missense variant, non coding transcript variant, intron variant
rs1225445157	C>T	Drug-response	Non coding transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant
rs1230347496	G>A	Drug-response	5 prime UTR variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1245588858	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1247954412	C>A	Drug-response	Coding sequence variant, intron variant, missense variant, upstream transcript variant, genic upstream transcript variant, 5 prime UTR variant
rs1252162127	T>A,C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant
rs1260131147	A>G	Drug-response	5 prime UTR variant, genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1266748899	G>A	Drug-response	5 prime UTR variant, genic downstream transcript variant, genic upstream transcript variant, intron variant
rs1280372606	C>G,T	Drug-response	Intron variant, genic downstream transcript variant
rs1290858635	T>A,C	Drug-response	Non coding transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, missense variant
rs1291536093	A>G,T	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant, genic downstream transcript variant
rs1292119568	T>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs1293588318	G>A,C	Drug-response	Intron variant, 5 prime UTR variant, genic upstream transcript variant, genic downstream transcript variant
rs1297476429	C>A,T	Drug-response	5 prime UTR variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant, intron variant, missense variant
rs1304233202	C>T	Drug-response	3 prime UTR variant, non coding transcript variant, downstream transcript variant, intron variant, genic downstream transcript variant
rs1312664080	G>A,C	Drug-response	Missense variant, 5 prime UTR variant, genic upstream transcript variant, intron variant, upstream transcript variant, coding sequence variant
rs1326499420	A>C,T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant
rs1339199018	T>C,G	Drug-response	3 prime UTR variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs1340096837	A>C,G	Drug-response	5 prime UTR variant, genic downstream transcript variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1347406881	C>A	Drug-response	Genic downstream transcript variant, non coding transcript variant, missense variant, coding sequence variant, intron variant
rs1347537120	A>C,T	Drug-response	Genic downstream transcript variant, intron variant
rs1348736608	C>T	Drug-response	Downstream transcript variant, genic downstream transcript variant, non coding transcript variant, 3 prime UTR variant, intron variant
rs1357614491	C>A,T	Drug-response	Downstream transcript variant, genic downstream transcript variant, non coding transcript variant, coding sequence variant, missense variant, intron variant
rs1358871698	C>A,T	Drug-response	Genic downstream transcript variant, intron variant
rs1368893702	G>A	Drug-response	5 prime UTR variant, genic upstream transcript variant, intron variant
rs1373421578	G>A	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant
rs1376751124	C>T	Drug-response	Genic downstream transcript variant, intron variant
rs1377052121	A>C,G	Drug-response	3 prime UTR variant, genic downstream transcript variant, non coding transcript variant, intron variant
rs1396848779	T>A,C	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1399307406	G>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs1411722881	C>-	Drug-response	Intron variant, frameshift variant, genic upstream transcript variant, non coding transcript variant, 5 prime UTR variant, coding sequence variant
rs1411786454	T>C,G	Drug-response	Intron variant, genic downstream transcript variant, non coding transcript variant, missense variant, coding sequence variant
rs1421882124	T>C	Drug-response	5 prime UTR variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1437740130	T>C,G	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant, non coding transcript variant
rs1442486722	A>-,AA	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant, non coding transcript variant
rs1465337438	C>A,T	Drug-response	5 prime UTR variant, coding sequence variant, intron variant, genic upstream transcript variant, missense variant, non coding transcript variant
rs1469997583	C>T	Drug-response	5 prime UTR variant, intron variant, coding sequence variant, genic upstream transcript variant, synonymous variant, upstream transcript variant
rs1482103571	C>G,T	Drug-response	Intron variant, non coding transcript variant, missense variant, coding sequence variant, genic upstream transcript variant
rs1562384714	G>A,T	Drug-response	Upstream transcript variant, 5 prime UTR variant, genic upstream transcript variant, intron variant
rs1562387533	G>C	Drug-response	Genic upstream transcript variant, intron variant
rs1583105193	C>T	Drug-response	Upstream transcript variant
rs1583105350	A>G	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105355	G>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105431	G>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105433	T>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105465	C>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105485	A>G	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105621	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105642	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105657	A>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105863	A>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105959	TC>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105979	A>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106074	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106084	G>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106153	G>T	Drug-response	Intron variant, genic upstream transcript variant
rs1583106204	G>T	Drug-response	Intron variant, genic upstream transcript variant
rs1583106304	AT>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583168957	C>A	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583168963	T>C	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583168972	C>A	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583169018	T>C	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583169368	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583169385	C>A	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583169899	T>A	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, upstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1583169988	G>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170034	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170107	G>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170298	G>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, upstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170659	G>A	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170710	G>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170716	C>T	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170728	T>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583171311	C>T	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583171446	C>T	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172139	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172146	C>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172783	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173066	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173231	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173318	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173471	G>C	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173482	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173537	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173570	C>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173845	GT>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173935	A>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583173984	G>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174062	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174146	C>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174701	C>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174793	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174921	G>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174969	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583175062	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583453568	T>C	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583453631	A>T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583454341	T>G	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583454446	A>C	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583454910	A>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583454933	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583454962	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455028	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455134	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455554	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456447	G>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456563	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456779	T>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456891	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456915	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456966	A>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457176	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457200	G>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457555	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457650	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583458111	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583458841	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459163	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459338	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459748	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459767	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459826	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459907	T>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460328	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460436	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460633	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460834	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460886	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460948	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461106	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461135	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461155	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461469	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461542	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461992	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583462573	G>T	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583462707	C>T	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583462789	T>C	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463133	T>-	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463193	G>A	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463210	G>T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463246	A>C,T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583475145	A>T	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475171	T>G	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475226	T>C	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475860	A>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583476221	T>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583476950	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477398	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477578	G>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477595	G>C	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477806	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478324	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478475	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478736	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479242	A>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479373	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479561	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583479779	T>-	Drug-response	Intron variant, genic downstream transcript variant
rs1583480107	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583480309	T>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583483080	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583483141	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583484799	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583484841	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485058	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485109	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485227	T>G	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant, stop gained
rs1583485720	T>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486157	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486285	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486994	T>C	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583487598	G>T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant, stop gained
rs1583487978	CT>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583488922	T>C	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489027	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489096	G>A	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489204	T>A	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583489460	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489837	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489871	T>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489915	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490024	G>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490295	T>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490437	A>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490466	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490491	T>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490520	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490544	T>G	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490805	AA>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490952	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491015	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491131	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491203	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491221	G>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491244	A>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491281	A>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491311	A>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491360	T>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491388	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491465	C>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491549	A>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492013	T>C	Drug-response	Missense variant, intron variant, 3 prime UTR variant, genic downstream transcript variant, coding sequence variant
rs1583492207	G>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492371	C>G	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492385	A>G	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492649	A>-	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant
rs1583492838	C>-	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant
rs1583498192	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498227	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498253	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583498287	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498344	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498416	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498470	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498695	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583498735	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498860	A>-	Drug-response	Intron variant, genic downstream transcript variant
rs1583498941	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498961	T>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498980	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499039	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583499129	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583499200	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499255	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583499305	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499402	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499617	C>-	Drug-response	Intron variant, genic downstream transcript variant, coding sequence variant, frameshift variant
rs1583499951	C>A	Drug-response	Intron variant, genic downstream transcript variant, synonymous variant, coding sequence variant
rs1583500066	G>A	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583500127	T>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583500706	T>C	Drug-response	Intron variant, genic downstream transcript variant, synonymous variant, coding sequence variant
rs1583502117	T>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583502202	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583502383	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1583502552	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1583576485	T>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583576504	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583576560	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583576581	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583576770	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583577388	A>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583577432	A>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583577918	A>C	Drug-response	Terminator codon variant, intron variant, genic downstream transcript variant, stop lost
rs1583578066	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583578847	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant
rs1583579146	C>-	Drug-response	Downstream transcript variant, intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579223	T>G	Drug-response	Downstream transcript variant, synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579274	T>C	Drug-response	Downstream transcript variant, synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579471	G>A	Drug-response	Downstream transcript variant, synonymous variant, intron variant, terminator codon variant, non coding transcript variant, genic downstream transcript variant
rs1583579544	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579747	T>-	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579780	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579976	A>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580011	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580059	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580161	A>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580176	A>G	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580562	A>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580623	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580736	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581065	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581242	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581365	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581395	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581810	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582181	C>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582271	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582311	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582329	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582348	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582470	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582588	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582674	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583367	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583459	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583588	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583598	A>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583705	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583861	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583986	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584064	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584184	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584208	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584227	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584237	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584273	G>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584685	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584843	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584876	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585064	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585088	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585235	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583590926	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583591171	G>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583591180	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583591643	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583618074	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583618090	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583618097	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583618112	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583618119	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583618157	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618505	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583618625	C>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618663	C>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618684	A>C	Drug-response	Splice acceptor variant, intron variant, genic downstream transcript variant
rs1583618696	C>T	Drug-response	Synonymous variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583618957	G>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583618998	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619099	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619112	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619173	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619209	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619229	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619237	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619245	TT>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619252	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619270	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619276	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619322	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619413	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619421	A>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619449	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619477	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619560	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619673	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619742	TC>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619765	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619797	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619824	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619875	AA>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619933	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619977	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620013	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620060	TT>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620067	C>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620083	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620088	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620109	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620169	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620181	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620216	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620267	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620288	C>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620348	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620362	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620394	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620400	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620413	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620422	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620432	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620448	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620546	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620663	G>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620668	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620690	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant

Show/Hide all(152)

miRTarBase ID	miRNA	Experiments	Reference
MIRT054667	hsa-miR-103a-3p	qRT-PCR	24302561
MIRT054667	hsa-miR-103a-3p	qRT-PCR	24302561
MIRT054668	hsa-miR-107	qRT-PCR	24302561
MIRT054668	hsa-miR-107	qRT-PCR	24302561
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR, Western blot	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assay, qRT-PCR	26052934
MIRT734252	hsa-let-7d-5p	Luciferase reporter assay, Western blotting, Immunohistochemistry (IHC), qRT-PCR	34124049
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT1204525	hsa-miR-3669	CLIP-seq
MIRT1204526	hsa-miR-4453	CLIP-seq
MIRT1204527	hsa-miR-4538	CLIP-seq
MIRT1204528	hsa-miR-493	CLIP-seq
MIRT1204529	hsa-miR-3622b-5p	CLIP-seq
MIRT1204525	hsa-miR-3669	CLIP-seq
MIRT1204530	hsa-miR-4725-5p	CLIP-seq
MIRT1204531	hsa-miR-4786-5p	CLIP-seq
MIRT1204532	hsa-miR-504	CLIP-seq
MIRT1204533	hsa-miR-769-5p	CLIP-seq
MIRT1204534	hsa-miR-1912	CLIP-seq
MIRT1204535	hsa-miR-3128	CLIP-seq
MIRT1204529	hsa-miR-3622b-5p	CLIP-seq
MIRT1204536	hsa-miR-4470	CLIP-seq
MIRT1204537	hsa-miR-4720-5p	CLIP-seq
MIRT1204538	hsa-miR-4799-3p	CLIP-seq
MIRT2585310	hsa-miR-4691-5p	CLIP-seq

Transcription factors

Show/Hide all(10)

Transcription factor	Regulation	Reference
JUN	Unknown	18523482
NFKB1	Unknown	18523482
REST	Repression	15322094;19913583
SP1	Activation	11675004
SP1	Unknown	17990281
SP3	Activation	11675004
STAT1	Activation	15448191
STAT3	Activation	15448191
STAT6	Unknown	20828825
YY1	Unknown	17990281

Show/Hide all(68)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001965	Function	G-protein alpha-subunit binding	IBA	21873635
GO:0001965	Function	G-protein alpha-subunit binding	IDA	20214800
GO:0002438	Process	Acute inflammatory response to antigenic stimulus	IEA
GO:0004930	Function	G protein-coupled receptor activity	IBA	21873635
GO:0004930	Function	G protein-coupled receptor activity	ISS
GO:0004979	Function	Beta-endorphin receptor activity	IBA	21873635
GO:0004979	Function	Beta-endorphin receptor activity	IMP	9689128
GO:0005245	Function	Voltage-gated calcium channel activity	ISS
GO:0005515	Function	Protein binding	IPI	14573758, 19788913, 20214800, 23597562, 23840749, 28298427
GO:0005768	Component	Endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	TAS	9242668
GO:0005794	Component	Golgi apparatus	TAS	9242668
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0005925	Component	Focal adhesion	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS
GO:0007187	Process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	TAS	7905839
GO:0007197	Process	Adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	ISS
GO:0007200	Process	Phospholipase C-activating G protein-coupled receptor signaling pathway	ISS
GO:0007218	Process	Neuropeptide signaling pathway	IBA	21873635
GO:0007600	Process	Sensory perception	NAS	9689128
GO:0008022	Function	Protein C-terminus binding	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	2159143
GO:0009314	Process	Response to radiation	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	TAS
GO:0019233	Process	Sensory perception of pain	IBA	21873635
GO:0019233	Process	Sensory perception of pain	ISS
GO:0019904	Function	Protein domain specific binding	IEA
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	ISS
GO:0031005	Function	Filamin binding	IEA
GO:0031635	Process	Adenylate cyclase-inhibiting opioid receptor signaling pathway	IEA
GO:0031681	Function	G-protein beta-subunit binding	IBA	21873635
GO:0032094	Process	Response to food	IEA
GO:0032100	Process	Positive regulation of appetite	IEA
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0032590	Component	Dendrite membrane	IEA
GO:0032839	Component	Dendrite cytoplasm	IEA
GO:0038003	Process	Opioid receptor signaling pathway	IBA	21873635
GO:0038003	Process	Opioid receptor signaling pathway	ISS
GO:0038047	Function	Morphine receptor activity	IBA	21873635
GO:0038047	Function	Morphine receptor activity	ISS
GO:0042060	Process	Wound healing	IEA
GO:0042220	Process	Response to cocaine	IEA
GO:0042277	Function	Peptide binding	IBA	21873635
GO:0042383	Component	Sarcolemma	IEA
GO:0042755	Process	Eating behavior	IEA
GO:0042923	Function	Neuropeptide binding	IBA	21873635
GO:0043005	Component	Neuron projection	IBA	21873635
GO:0043204	Component	Perikaryon	IEA
GO:0044849	Process	Estrous cycle	IEA
GO:0045121	Component	Membrane raft	IEA
GO:0048149	Process	Behavioral response to ethanol	IMP	21039637
GO:0050769	Process	Positive regulation of neurogenesis	ISS
GO:0051930	Process	Regulation of sensory perception of pain	IEA
GO:0060079	Process	Excitatory postsynaptic potential	IEA
GO:0061358	Process	Negative regulation of Wnt protein secretion	IMP	20214800
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	ISS
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0070848	Process	Response to growth factor	IEA
GO:0071315	Process	Cellular response to morphine	IEA
GO:0080135	Process	Regulation of cellular response to stress	IMP	21039637
GO:0097444	Component	Spine apparatus	IEA
GO:0099055	Component	Integral component of postsynaptic membrane	IEA
GO:0099056	Component	Integral component of presynaptic membrane	IEA
GO:0106072	Process	Negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA
GO:2000310	Process	Regulation of NMDA receptor activity	ISS

MIM	HGNC	e!Ensembl
600018	8156	ENSG00000112038

Protein

UniProt ID

P35372

Protein name

Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)

Protein function

Receptor for endogenous opioids such as beta-endorphin and endomorphin (PubMed:10529478, PubMed:12589820, PubMed:7891175, PubMed:7905839, PubMed:7957926, PubMed:9689128). Receptor for natural and synthetic opioids including morphine, heroin, DAM

PDB

8EF5 , 8EF6 , 8EFB , 8EFL , 8EFO , 8EFQ , 8F7Q , 8F7R , 8K9K , 8K9L , 9MQH , 9MQI , 9MQJ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	87 → 338	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain. Isoform 16 and isoform 17 are detected in brain. {ECO:0000269|PubMed:16580639}.

Sequence

MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP

Sequence length

400

Interactions

View interactions

	KEGG		Reactome
	Neuroactive ligand-receptor interaction Hormone signaling Estrogen signaling pathway Morphine addiction		Opioid Signalling G-protein activation Peptide ligand-binding receptors G alpha (i) signalling events Interleukin-4 and Interleukin-13 signaling

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Epilepsy	Epilepsy, Epilepsy, Cryptogenic, Awakening Epilepsy	rs113994140, rs28937874, rs1589762127, rs104894166, rs28939075, rs2134001459, rs104894167, rs119488099, rs119488100, rs387906420, rs121917752, rs121918622, rs281865564, rs387907313, rs397514670 View all (165 more)	2415332
Schizophrenia	Schizophrenia, SCHIZOPHRENIA 12	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	23560613, 22925223, 20112002
Seizure	Complex partial seizures, Generalized seizures, Visual seizure, Tonic - clonic seizures, Single Seizure	rs587784365, rs28939683, rs74315390, rs28939684, rs74315391, rs267607198, rs74315392, rs118192244, rs118192250, rs121917749, rs121917750, rs121917751, rs121917752, rs267606670, rs267607061 View all (179 more)	18042875, 1675896

Show/Hide Unknown Diseases (7)

Disease term	Disease name	References	Source
Unknown
Mental depression	Mental Depression, Depressive disorder, Depression, Postpartum	25286107, 19596019, 24766998, 21703297, 21459516	ClinVar
Asthma	Asthma		GWAS
Hypertension	Hypertension		GWAS
Lymphocytic Leukemia	Lymphocytic Leukemia		GWAS
Diabetes	Diabetes		GWAS
Metabolic Syndrome	Metabolic Syndrome		GWAS
Dermatitis	Dermatitis		GWAS

Show/Hide Text Mining Associations (99)

Disease Name	Relationship Type	References
Associations from Text Mining
Acute Pain	Associate	24884878
Alcohol Related Disorders	Associate	26228411
Alcohol Withdrawal Delirium	Associate	30085428
Alcoholism	Associate	19736238, 27109624, 30085428
Alzheimer Disease	Associate	30152845
Anxiety	Associate	30656852, 31553235
Asthma	Associate	36395102
Atherosclerosis	Associate	25613305
Attention Deficit Disorder with Hyperactivity	Associate	22841130
Binge Drinking	Associate	22143634
Binge Eating Disorder	Associate	19282821
Breast Neoplasms	Associate	25239082, 25618602, 35727214, 36672750, 36942908
Cancer Pain	Associate	17156920, 23803057, 28346387, 30700073, 35710811
Carcinoma Non Small Cell Lung	Associate	22003224
Carcinoma Pancreatic Ductal	Associate	27682590
Cerebral Small Vessel Diseases	Associate	25613305
Cholestasis	Associate	18709298
Chronic Pain	Associate	23803057, 30700073, 32098316, 36672750, 36942908
Colorectal Neoplasms	Associate	35983971, 37217861
Compulsive Personality Disorder	Associate	35960604
Constipation	Associate	36942908
Cystitis Interstitial	Associate	30973927
Dental Caries	Associate	30973902
Depressive Disorder	Associate	26228411, 30656852, 31553235, 32492095
Disorders of Excessive Somnolence	Associate	34871222
Disruptive Impulse Control and Conduct Disorders	Associate	31553235
Drug Fever	Stimulate	35182225
Drug Overdose	Associate	23318993
Drug Related Side Effects and Adverse Reactions	Associate	36988399
Dyskinesia Drug Induced	Associate	34599261
Dyslexia	Associate	37667328
Dysmenorrhea	Associate	28057931
Encephalitis	Associate	24413261, 27400929
Endometriosis	Associate	28256208
Fibromyalgia	Associate	29486785, 32098316, 33064887, 36342939
Food Addiction	Associate	23670889
Gambling	Associate	31553235
Glioma	Associate	33315125
Headache	Associate	22752568
Heart Arrest	Associate	23318993
HIV Infections	Associate	22457278, 24413261, 27400929
Idiopathic Noncirrhotic Portal Hypertension	Associate	19736238
Inflammation	Associate	16299031
Inflammation	Inhibit	31801206
Inflammatory Bowel Diseases	Associate	16299031
Intervertebral disc disease	Associate	22815498
Intervertebral Disc Displacement	Associate	22815498, 24884878
Intestinal Neoplasms	Associate	31773688
Irritable Bowel Syndrome	Stimulate	31336406
Leukemia	Associate	28650467
Liver Cirrhosis Biliary	Associate	18709298
Low Back Pain	Associate	22815498
Lung Neoplasms	Associate	22003224, 24662916, 24920011, 30455395
Lymphatic Metastasis	Associate	35983971
Melanoma	Associate	17897634, 29577418
Mental Disorders	Associate	31553235, 32492095, 9790747
Microcephaly cervical spine fusion anomalies	Associate	25266679
Migraine Disorders	Associate	22752568
Motor Disorders	Associate	25842347
Muscle Hypertonia	Associate	34971656
Musculoskeletal Pain	Associate	25842347
Neonatal Abstinence Syndrome	Associate	34971656
Neoplasm Metastasis	Associate	28346387
Neoplasms	Associate	24104703, 24662916, 24920011, 25618602, 30229370, 32900505, 33848569, 35182225, 35983971
Neoplasms Adipose Tissue	Associate	23917806
Neurocognitive Disorders	Associate	24413261
Neuropathy Painful	Associate	21837673
Neurotoxicity Syndromes	Associate	23963862
Obesity	Associate	19008867, 23917806, 29662095
Opioid Related Disorders	Associate	23318993, 31246565, 32492095
Osteoarthritis	Associate	32098316
Ovarian Diseases	Associate	16815388
Ovarian Neoplasms	Associate	35033381, 36988399
Pain	Associate	17156920, 20003118, 22752568, 22815498, 23318993, 23803057, 24884878, 25239082, 25308352, 25618602, 25842347, 26945673, 28057931, 30973927, 31755291 View all (9 more)
Pain Postoperative	Associate	20003118, 31773688, 40331998
Pancreatic Neoplasms	Associate	27682590
Parkinson Disease	Associate	35960604
Periodontitis	Associate	30973902, 36395102
Postoperative Hemorrhage	Associate	31773688
Precursor Cell Lymphoblastic Leukemia Lymphoma	Stimulate	28650467
Prostatic Neoplasms	Associate	24104703
Pruritus	Associate	18709298
Respiratory Insufficiency	Associate	23318993, 25266679
Rhinitis Atrophic	Associate	35299869
Schizophrenia	Associate	28548579
Sciatica	Associate	22815498
Seizures	Associate	30085428
Shoulder Pain	Associate	35727214, 36672750
Sleep Wake Disorders	Associate	30700073
Smoke Inhalation Injury	Associate	30973902
Social Communication Disorder	Associate	30656852
Squamous Cell Carcinoma of Head and Neck	Associate	32900505
Stomach Neoplasms	Associate	31773688
Stress Disorders Post Traumatic	Associate	22143634
Substance Related Disorders	Associate	18384978, 21070507, 22841130, 25308352, 31246565, 38118075, 9790747
Tooth Loss	Associate	30973902
Tourette Syndrome	Associate	36674940
Weight Gain	Associate	29662095
Wounds and Injuries	Associate	25842347

OPRM1 (opioid receptor mu 1)