Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	4988
Gene name	Opioid receptor mu 1
Gene symbol	OPRM1
Synonyms (NCBI Gene)	LMORM-OR-1MOPMORMOR1OPRM
Chromosome	6
Chromosome location	6q25.2
Summary	This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an importa

453

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SNP ID	Visualize variation	Clinical significance	Consequence
rs497332	C>A,G,T	Drug-response	Genic downstream transcript variant, intron variant
rs540825	A>C,G,T	Drug-response	Intron variant, synonymous variant, missense variant, genic downstream transcript variant, coding sequence variant
rs562859	C>A,G,T	Drug-response	Intron variant, synonymous variant, missense variant, genic downstream transcript variant, coding sequence variant
rs563649	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, genic downstream transcript variant
rs606545	G>A,C	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant, non coding transcript variant
rs623956	A>G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant, non coding transcript variant
rs650245	A>C,G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant
rs650825	G>A	Drug-response	Genic downstream transcript variant, intron variant
rs675026	A>C,G	Drug-response	Genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs677830	C>A,G,T	Drug-response, benign	Intron variant, missense variant, genic downstream transcript variant, stop gained, coding sequence variant
rs1799971	A>G	Drug-response, uncertain-significance	Intron variant, missense variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant
rs2075572	G>C	Drug-response	Genic downstream transcript variant, intron variant
rs6912029	G>T	Drug-response	5 prime UTR variant, intron variant, coding sequence variant, upstream transcript variant, missense variant, genic upstream transcript variant
rs9282821	A>C,T	Drug-response	Intron variant, genic downstream transcript variant
rs9322446	G>A	Drug-response	5 prime UTR variant, genic upstream transcript variant, intron variant, genic downstream transcript variant
rs9479757	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs11575858	C>T	Drug-response	3 prime UTR variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs17174794	C>G,T	Benign, drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, missense variant, coding sequence variant
rs17181192	T>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs41292890	C>T	Drug-response	Non coding transcript variant, genic upstream transcript variant, synonymous variant, intron variant, coding sequence variant, 5 prime UTR variant
rs60254893	C>G,T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs62638690	G>T	Drug-response	Non coding transcript variant, missense variant, genic downstream transcript variant, intron variant, coding sequence variant
rs71021021	TTTTTT>-,TTTTT,TTTTTTT,TTTTTTTTTT	Drug-response	Non coding transcript variant, downstream transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant
rs77696469	C>G,T	Drug-response	Non coding transcript variant, intron variant, 3 prime UTR variant, genic downstream transcript variant
rs78937301	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs113270588	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant
rs114492858	C>G,T	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, downstream transcript variant, genic downstream transcript variant
rs115788842	T>A	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant
rs139944762	C>A,T	Drug-response	Genic downstream transcript variant, 5 prime UTR variant, intron variant, genic upstream transcript variant
rs140560182	G>A	Drug-response	Genic downstream transcript variant, intron variant, downstream transcript variant
rs150821368	C>T	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant, downstream transcript variant
rs184553578	C>A,T	Drug-response	Missense variant, genic downstream transcript variant, non coding transcript variant, intron variant, coding sequence variant
rs186439043	C>T	Drug-response	Intron variant, coding sequence variant, missense variant, genic downstream transcript variant
rs199648369	C>G,T	Drug-response	Genic upstream transcript variant, coding sequence variant, 5 prime UTR variant, non coding transcript variant, intron variant, missense variant
rs199650905	C>T	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs199878364	C>T	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs199942335	G>A,C	Drug-response	Coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs200245799	G>A,C	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic downstream transcript variant
rs200512398	C>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, synonymous variant, stop gained, genic downstream transcript variant
rs200587105	G>A,C	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs200646591	G>A	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs200803187	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs200869983	C>T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, stop gained, genic downstream transcript variant
rs200915701	C>T	Drug-response	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, synonymous variant
rs201126701	G>A	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs201310502	C>G,T	Drug-response	Genic upstream transcript variant, coding sequence variant, non coding transcript variant, intron variant, missense variant
rs201518555	A>C,G	Drug-response	3 prime UTR variant, non coding transcript variant, intron variant, genic downstream transcript variant
rs201750445	G>A,T	Drug-response	Intron variant, genic downstream transcript variant
rs201829386	C>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic downstream transcript variant
rs201858274	G>A,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, stop gained, missense variant, genic downstream transcript variant
rs370868117	C>T	Drug-response	Genic upstream transcript variant, coding sequence variant, 5 prime UTR variant, missense variant, non coding transcript variant, intron variant
rs377704466	G>A	Drug-response	Genic upstream transcript variant, intron variant
rs536957156	G>A,C	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant
rs542615961	C>A,T	Drug-response	Non coding transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant, downstream transcript variant
rs546524303	G>A,T	Drug-response	Upstream transcript variant, genic upstream transcript variant, intron variant
rs552928147	A>C,G	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs557690438	A>G,T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs567300902	G>A	Drug-response	Non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, intron variant
rs571470402	A>C,G	Drug-response	Genic upstream transcript variant, intron variant, upstream transcript variant
rs573698787	C>T	Drug-response	Genic downstream transcript variant, intron variant, 3 prime UTR variant
rs577345039	C>G,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic upstream transcript variant
rs745863104	C>A,G,T	Drug-response	Coding sequence variant, non coding transcript variant, intron variant, missense variant, genic upstream transcript variant, synonymous variant
rs747345350	C>A,G	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs747772652	A>C,G	Drug-response	Intron variant, coding sequence variant, non coding transcript variant, missense variant, genic upstream transcript variant
rs749003633	C>T	Drug-response	Intron variant, stop gained, coding sequence variant, non coding transcript variant, genic downstream transcript variant
rs751081299	T>C,G	Drug-response	Intron variant, coding sequence variant, non coding transcript variant, missense variant, genic downstream transcript variant
rs765963522	C>T	Drug-response	Intron variant, coding sequence variant, synonymous variant, genic downstream transcript variant, non coding transcript variant
rs767783492	G>A,T	Drug-response	Genic downstream transcript variant, intron variant, coding sequence variant, missense variant
rs768115985	A>C	Drug-response	Genic downstream transcript variant, intron variant, stop lost, terminator codon variant
rs769540300	G>A	Drug-response	Intron variant, coding sequence variant, missense variant, genic downstream transcript variant, non coding transcript variant
rs769686797	G>A,C	Drug-response	Genic upstream transcript variant, intron variant
rs771278948	A>-,AA	Drug-response	Genic downstream transcript variant, intron variant
rs776184873	G>A	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant, genic upstream transcript variant
rs778238775	G>A,T	Drug-response	Non coding transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs778888827	T>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs898784845	A>G	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant
rs914204741	C>G,T	Drug-response	Intron variant, genic downstream transcript variant
rs937431474	G>A,C	Drug-response	Genic downstream transcript variant, 5 prime UTR variant, intron variant, genic upstream transcript variant
rs947787494	C>A,G	Drug-response	Downstream transcript variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, intron variant
rs958018897	G>A	Drug-response	3 prime UTR variant, genic downstream transcript variant, intron variant, non coding transcript variant
rs968231224	C>T	Drug-response	3 prime UTR variant, genic downstream transcript variant, intron variant, non coding transcript variant
rs972892962	G>A	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, intron variant
rs979061434	C>G,T	Drug-response	Coding sequence variant, genic downstream transcript variant, missense variant, intron variant
rs984634670	G>A	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs986844324	C>G	Drug-response	Intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs994797893	C>T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, 3 prime UTR variant, downstream transcript variant
rs1014331595	G>A,C,T	Drug-response	Genic downstream transcript variant, non coding transcript variant, intron variant, 3 prime UTR variant
rs1017227710	G>A	Drug-response	Genic downstream transcript variant, intron variant, 3 prime UTR variant
rs1033852015	A>G	Drug-response	Genic downstream transcript variant, genic upstream transcript variant, 5 prime UTR variant, intron variant
rs1160295304	C>T	Drug-response	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, missense variant, intron variant
rs1160455955	G>A	Drug-response	Genic downstream transcript variant, downstream transcript variant, intron variant
rs1169090293	A>G	Drug-response	Coding sequence variant, non coding transcript variant, genic downstream transcript variant, intron variant, downstream transcript variant, synonymous variant
rs1178930557	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1183268180	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1190969003	C>T	Drug-response	Non coding transcript variant, synonymous variant, coding sequence variant, intron variant, genic upstream transcript variant
rs1201764699	C>T	Drug-response	Intron variant, 5 prime UTR variant, genic downstream transcript variant, genic upstream transcript variant
rs1210793358	A>G	Drug-response	Genic downstream transcript variant, coding sequence variant, missense variant, non coding transcript variant, intron variant
rs1225445157	C>T	Drug-response	Non coding transcript variant, 3 prime UTR variant, intron variant, genic downstream transcript variant
rs1230347496	G>A	Drug-response	5 prime UTR variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1245588858	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1247954412	C>A	Drug-response	Coding sequence variant, intron variant, missense variant, upstream transcript variant, genic upstream transcript variant, 5 prime UTR variant
rs1252162127	T>A,C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant
rs1260131147	A>G	Drug-response	5 prime UTR variant, genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1266748899	G>A	Drug-response	5 prime UTR variant, genic downstream transcript variant, genic upstream transcript variant, intron variant
rs1280372606	C>G,T	Drug-response	Intron variant, genic downstream transcript variant
rs1290858635	T>A,C	Drug-response	Non coding transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, missense variant
rs1291536093	A>G,T	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant, genic downstream transcript variant
rs1292119568	T>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs1293588318	G>A,C	Drug-response	Intron variant, 5 prime UTR variant, genic upstream transcript variant, genic downstream transcript variant
rs1297476429	C>A,T	Drug-response	5 prime UTR variant, non coding transcript variant, genic upstream transcript variant, coding sequence variant, intron variant, missense variant
rs1304233202	C>T	Drug-response	3 prime UTR variant, non coding transcript variant, downstream transcript variant, intron variant, genic downstream transcript variant
rs1312664080	G>A,C	Drug-response	Missense variant, 5 prime UTR variant, genic upstream transcript variant, intron variant, upstream transcript variant, coding sequence variant
rs1326499420	A>C,T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant
rs1339199018	T>C,G	Drug-response	3 prime UTR variant, intron variant, non coding transcript variant, genic downstream transcript variant
rs1340096837	A>C,G	Drug-response	5 prime UTR variant, genic downstream transcript variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1347406881	C>A	Drug-response	Genic downstream transcript variant, non coding transcript variant, missense variant, coding sequence variant, intron variant
rs1347537120	A>C,T	Drug-response	Genic downstream transcript variant, intron variant
rs1348736608	C>T	Drug-response	Downstream transcript variant, genic downstream transcript variant, non coding transcript variant, 3 prime UTR variant, intron variant
rs1357614491	C>A,T	Drug-response	Downstream transcript variant, genic downstream transcript variant, non coding transcript variant, coding sequence variant, missense variant, intron variant
rs1358871698	C>A,T	Drug-response	Genic downstream transcript variant, intron variant
rs1368893702	G>A	Drug-response	5 prime UTR variant, genic upstream transcript variant, intron variant
rs1373421578	G>A	Drug-response	Genic downstream transcript variant, 3 prime UTR variant, non coding transcript variant, intron variant
rs1376751124	C>T	Drug-response	Genic downstream transcript variant, intron variant
rs1377052121	A>C,G	Drug-response	3 prime UTR variant, genic downstream transcript variant, non coding transcript variant, intron variant
rs1396848779	T>A,C	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1399307406	G>A,C	Drug-response	Intron variant, genic downstream transcript variant
rs1411722881	C>-	Drug-response	Intron variant, frameshift variant, genic upstream transcript variant, non coding transcript variant, 5 prime UTR variant, coding sequence variant
rs1411786454	T>C,G	Drug-response	Intron variant, genic downstream transcript variant, non coding transcript variant, missense variant, coding sequence variant
rs1421882124	T>C	Drug-response	5 prime UTR variant, intron variant, upstream transcript variant, genic upstream transcript variant
rs1437740130	T>C,G	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant, non coding transcript variant
rs1442486722	A>-,AA	Drug-response	3 prime UTR variant, intron variant, genic downstream transcript variant, non coding transcript variant
rs1465337438	C>A,T	Drug-response	5 prime UTR variant, coding sequence variant, intron variant, genic upstream transcript variant, missense variant, non coding transcript variant
rs1469997583	C>T	Drug-response	5 prime UTR variant, intron variant, coding sequence variant, genic upstream transcript variant, synonymous variant, upstream transcript variant
rs1482103571	C>G,T	Drug-response	Intron variant, non coding transcript variant, missense variant, coding sequence variant, genic upstream transcript variant
rs1562384714	G>A,T	Drug-response	Upstream transcript variant, 5 prime UTR variant, genic upstream transcript variant, intron variant
rs1562387533	G>C	Drug-response	Genic upstream transcript variant, intron variant
rs1583105193	C>T	Drug-response	Upstream transcript variant
rs1583105350	A>G	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105355	G>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105431	G>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105433	T>A	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105465	C>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105485	A>G	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105621	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105642	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105657	A>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105863	A>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105959	TC>-	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583105979	A>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106074	C>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106084	G>T	Drug-response	Intron variant, genic upstream transcript variant, 5 prime UTR variant
rs1583106153	G>T	Drug-response	Intron variant, genic upstream transcript variant
rs1583106204	G>T	Drug-response	Intron variant, genic upstream transcript variant
rs1583106304	AT>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583168957	C>A	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583168963	T>C	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583168972	C>A	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583169018	T>C	Drug-response	Intron variant, genic upstream transcript variant, upstream transcript variant
rs1583169368	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583169385	C>A	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583169899	T>A	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, upstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1583169988	G>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170034	C>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170107	G>T	Drug-response	Genic upstream transcript variant, intron variant, 5 prime UTR variant, upstream transcript variant
rs1583170298	G>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, upstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170659	G>A	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170710	G>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170716	C>T	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583170728	T>A	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583171311	C>T	Drug-response	Missense variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583171446	C>T	Drug-response	Synonymous variant, intron variant, 5 prime UTR variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172139	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172146	C>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583172783	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173066	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173231	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173318	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173471	G>C	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173482	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173537	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173570	C>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173845	GT>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, coding sequence variant, genic upstream transcript variant
rs1583173935	A>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583173984	G>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174062	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174146	C>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174701	C>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174793	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583174921	G>-	Drug-response	Intron variant, genic upstream transcript variant
rs1583174969	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583175062	G>A	Drug-response	Intron variant, genic upstream transcript variant
rs1583453568	T>C	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583453631	A>T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583454341	T>G	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583454446	A>C	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583454910	A>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583454933	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583454962	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455028	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455134	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583455554	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456447	G>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456563	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456779	T>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456891	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456915	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583456966	A>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457176	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457200	G>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457555	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583457650	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583458111	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583458841	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459163	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459338	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459748	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459767	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459826	A>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583459907	T>C	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460328	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460436	C>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460633	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460834	T>-	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460886	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583460948	C>T	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461106	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461135	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461155	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461469	A>G	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461542	T>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583461992	G>A	Drug-response	Genic upstream transcript variant, intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583462573	G>T	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583462707	C>T	Drug-response	Intron variant, 5 prime UTR variant, upstream transcript variant, genic downstream transcript variant, genic upstream transcript variant
rs1583462789	T>C	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463133	T>-	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463193	G>A	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463210	G>T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583463246	A>C,T	Drug-response	Intron variant, genic downstream transcript variant, genic upstream transcript variant, upstream transcript variant
rs1583475145	A>T	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475171	T>G	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475226	T>C	Drug-response	Intron variant, genic downstream transcript variant, 5 prime UTR variant
rs1583475860	A>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583476221	T>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583476950	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477398	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477578	G>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477595	G>C	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583477806	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478324	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478475	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583478736	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479242	A>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479373	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583479561	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583479779	T>-	Drug-response	Intron variant, genic downstream transcript variant
rs1583480107	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583480309	T>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583483080	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583483141	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583484799	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583484841	C>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485058	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485109	T>G	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583485227	T>G	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant, stop gained
rs1583485720	T>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486157	C>T	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486285	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583486994	T>C	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583487598	G>T	Drug-response	Intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant, stop gained
rs1583487978	CT>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583488922	T>C	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489027	C>A	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489096	G>A	Drug-response	Synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583489204	T>A	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583489460	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489837	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489871	T>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583489915	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490024	G>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490295	T>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490437	A>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490466	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490491	T>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490520	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490544	T>G	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490805	AA>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583490952	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491015	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491131	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491203	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491221	G>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491244	A>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491281	A>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491311	A>C	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491360	T>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491388	C>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491465	C>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583491549	A>T	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492013	T>C	Drug-response	Missense variant, intron variant, 3 prime UTR variant, genic downstream transcript variant, coding sequence variant
rs1583492207	G>-	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492371	C>G	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492385	A>G	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant, 3 prime UTR variant
rs1583492649	A>-	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant
rs1583492838	C>-	Drug-response	Intron variant, downstream transcript variant, genic downstream transcript variant
rs1583498192	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498227	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498253	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583498287	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498344	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498416	C>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498470	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498695	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583498735	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583498860	A>-	Drug-response	Intron variant, genic downstream transcript variant
rs1583498941	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498961	T>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583498980	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499039	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583499129	G>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583499200	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499255	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583499305	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499402	A>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583499617	C>-	Drug-response	Intron variant, genic downstream transcript variant, coding sequence variant, frameshift variant
rs1583499951	C>A	Drug-response	Intron variant, genic downstream transcript variant, synonymous variant, coding sequence variant
rs1583500066	G>A	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583500127	T>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583500706	T>C	Drug-response	Intron variant, genic downstream transcript variant, synonymous variant, coding sequence variant
rs1583502117	T>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583502202	C>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583502383	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1583502552	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant, 3 prime UTR variant
rs1583576485	T>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583576504	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583576560	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583576581	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583576770	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583577388	A>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583577432	A>C	Drug-response	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs1583577918	A>C	Drug-response	Terminator codon variant, intron variant, genic downstream transcript variant, stop lost
rs1583578066	G>A	Drug-response	Intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583578847	G>A	Drug-response	Intron variant, genic downstream transcript variant, downstream transcript variant
rs1583579146	C>-	Drug-response	Downstream transcript variant, intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579223	T>G	Drug-response	Downstream transcript variant, synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579274	T>C	Drug-response	Downstream transcript variant, synonymous variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583579471	G>A	Drug-response	Downstream transcript variant, synonymous variant, intron variant, terminator codon variant, non coding transcript variant, genic downstream transcript variant
rs1583579544	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579747	T>-	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579780	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583579976	A>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580011	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580059	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580161	A>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580176	A>G	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580562	A>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580623	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583580736	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581065	T>C	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581242	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581365	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581395	C>T	Drug-response	Downstream transcript variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant
rs1583581810	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582181	C>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582271	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582311	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582329	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582348	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582470	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582588	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583582674	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583367	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583459	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583588	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583598	A>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583705	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583861	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583583986	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584064	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584184	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584208	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584227	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584237	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584273	G>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584685	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584843	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583584876	A>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585064	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585088	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583585235	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583590926	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583591171	G>T	Drug-response	Missense variant, intron variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583591180	A>-	Drug-response	Intron variant, frameshift variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583591643	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583618074	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583618090	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583618097	G>A	Drug-response	Intron variant, genic downstream transcript variant
rs1583618112	T>C	Drug-response	Intron variant, genic downstream transcript variant
rs1583618119	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583618157	A>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618505	C>T	Drug-response	Intron variant, genic downstream transcript variant
rs1583618625	C>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618663	C>G	Drug-response	Intron variant, genic downstream transcript variant
rs1583618684	A>C	Drug-response	Splice acceptor variant, intron variant, genic downstream transcript variant
rs1583618696	C>T	Drug-response	Synonymous variant, intron variant, 3 prime UTR variant, non coding transcript variant, genic downstream transcript variant, coding sequence variant
rs1583618957	G>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583618998	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619099	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619112	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619173	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619209	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619229	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619237	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619245	TT>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619252	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619270	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619276	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619322	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619413	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619421	A>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619449	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619477	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619560	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619673	A>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619742	TC>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619765	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619797	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619824	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619875	AA>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619933	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583619977	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620013	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620060	TT>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620067	C>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620083	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620088	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620109	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620169	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620181	T>-	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620216	T>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620267	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620288	C>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620348	C>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620362	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620394	A>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620400	G>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620413	T>G	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620422	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620432	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620448	G>A	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620546	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620663	G>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620668	T>C	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant
rs1583620690	C>T	Drug-response	Non coding transcript variant, intron variant, genic downstream transcript variant, 3 prime UTR variant

152

Show/Hide all (152)

miRTarBase ID	miRNA	Experiments	Reference
MIRT054667	hsa-miR-103a-3p	qRT-PCR	24302561
MIRT054667	hsa-miR-103a-3p	qRT-PCR	24302561
MIRT054668	hsa-miR-107	qRT-PCR	24302561
MIRT054668	hsa-miR-107	qRT-PCR	24302561
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT732142	hsa-miR-16-5p	Luciferase reporter assayqRT-PCRWestern blot	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assayqRT-PCR	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assayqRT-PCR	26052934
MIRT732142	hsa-miR-16-5p	Luciferase reporter assayqRT-PCR	26052934
MIRT734252	hsa-let-7d-5p	Luciferase reporter assayWestern blottingImmunohistochemistry (IHC)qRT-PCR	34124049
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT640485	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT640484	hsa-miR-4743-3p	HITS-CLIP	23824327
MIRT640483	hsa-miR-4652-3p	HITS-CLIP	23824327
MIRT618118	hsa-miR-3927-5p	HITS-CLIP	23824327
MIRT618117	hsa-miR-6845-3p	HITS-CLIP	23824327
MIRT618116	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618115	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618114	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT618113	hsa-miR-564	HITS-CLIP	23824327
MIRT618112	hsa-miR-337-3p	HITS-CLIP	23824327
MIRT618111	hsa-miR-202-5p	HITS-CLIP	23824327
MIRT618110	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618109	hsa-miR-3685	HITS-CLIP	23824327
MIRT618108	hsa-miR-384	HITS-CLIP	23824327
MIRT618107	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT618106	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT618105	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT1204525	hsa-miR-3669	CLIP-seq
MIRT1204526	hsa-miR-4453	CLIP-seq
MIRT1204527	hsa-miR-4538	CLIP-seq
MIRT1204528	hsa-miR-493	CLIP-seq
MIRT1204529	hsa-miR-3622b-5p	CLIP-seq
MIRT1204525	hsa-miR-3669	CLIP-seq
MIRT1204530	hsa-miR-4725-5p	CLIP-seq
MIRT1204531	hsa-miR-4786-5p	CLIP-seq
MIRT1204532	hsa-miR-504	CLIP-seq
MIRT1204533	hsa-miR-769-5p	CLIP-seq
MIRT1204534	hsa-miR-1912	CLIP-seq
MIRT1204535	hsa-miR-3128	CLIP-seq
MIRT1204529	hsa-miR-3622b-5p	CLIP-seq
MIRT1204536	hsa-miR-4470	CLIP-seq
MIRT1204537	hsa-miR-4720-5p	CLIP-seq
MIRT1204538	hsa-miR-4799-3p	CLIP-seq
MIRT2585310	hsa-miR-4691-5p	CLIP-seq

Show/Hide all (10)

Transcription factor	Regulation	Reference
JUN	Unknown	18523482
NFKB1	Unknown	18523482
REST	Repression	15322094;19913583
SP1	Activation	11675004
SP1	Unknown	17990281
SP3	Activation	11675004
STAT1	Activation	15448191
STAT3	Activation	15448191
STAT6	Unknown	20828825
YY1	Unknown	17990281

Show/Hide all (57)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001965	Function	G-protein alpha-subunit binding	IBA
GO:0001965	Function	G-protein alpha-subunit binding	IDA	20214800
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	ISS
GO:0004979	Function	Beta-endorphin receptor activity	IBA
GO:0004979	Function	Beta-endorphin receptor activity	IEA
GO:0004979	Function	Beta-endorphin receptor activity	IMP	9689128
GO:0004985	Function	G protein-coupled opioid receptor activity	IEA
GO:0005245	Function	Voltage-gated calcium channel activity	ISS
GO:0005515	Function	Protein binding	IPI	14573758, 19788913, 20214800, 23597562, 23840749, 28298427, 32296183
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005768	Component	Endosome	ISS
GO:0005783	Component	Endoplasmic reticulum	TAS	9242668
GO:0005794	Component	Golgi apparatus	TAS	9242668
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS	7905839, 9242668
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IDA	20214800
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007187	Process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	TAS	7905839
GO:0007193	Process	Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	IDA	20525224
GO:0007197	Process	Adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	ISS
GO:0007200	Process	Phospholipase C-activating G protein-coupled receptor signaling pathway	ISS
GO:0007218	Process	Neuropeptide signaling pathway	IBA
GO:0007600	Process	Sensory perception	NAS	9689128
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	2159143
GO:0008528	Function	G protein-coupled peptide receptor activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0019233	Process	Sensory perception of pain	IBA
GO:0019233	Process	Sensory perception of pain	ISS
GO:0030424	Component	Axon	IEA
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	IEA
GO:0030425	Component	Dendrite	ISS
GO:0031681	Function	G-protein beta-subunit binding	IBA
GO:0038003	Process	G protein-coupled opioid receptor signaling pathway	IBA
GO:0038003	Process	G protein-coupled opioid receptor signaling pathway	ISS
GO:0038047	Function	Morphine receptor activity	IBA
GO:0038047	Function	Morphine receptor activity	ISS
GO:0042923	Function	Neuropeptide binding	IBA
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IBA
GO:0043204	Component	Perikaryon	IEA
GO:0045019	Process	Negative regulation of nitric oxide biosynthetic process	IDA	20525224
GO:0045202	Component	Synapse	IEA
GO:0048149	Process	Behavioral response to ethanol	IMP	21039637
GO:0050769	Process	Positive regulation of neurogenesis	ISS
GO:0051481	Process	Negative regulation of cytosolic calcium ion concentration	IDA	20525224
GO:0061358	Process	Negative regulation of Wnt protein secretion	IMP	20214800
GO:0070374	Process	Positive regulation of ERK1 and ERK2 cascade	ISS
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0071315	Process	Cellular response to morphine	IEA
GO:0080135	Process	Regulation of cellular response to stress	IMP	21039637
GO:2000310	Process	Regulation of NMDA receptor activity	ISS

MIM	HGNC	e!Ensembl
600018	8156	ENSG00000112038

P35372

Protein name

Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)

Protein function

Receptor for endogenous opioids such as beta-endorphin and endomorphin (PubMed:10529478, PubMed:12589820, PubMed:7891175, PubMed:7905839, PubMed:7957926, PubMed:9689128). Receptor for natural and synthetic opioids including morphine, heroin, DAM

PDB

8EF5 , 8EF6 , 8EFB , 8EFL , 8EFO , 8EFQ , 8F7Q , 8F7R , 8K9K , 8K9L , 9MQH , 9MQI , 9MQJ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00001	7tm_1	87 → 338	7 transmembrane receptor (rhodopsin family)	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain. Isoform 16 and isoform 17 are detected in brain. {ECO:0000269|PubMed:16580639}.

Sequence

MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP

Sequence length

400

Interactions

View interactions

	KEGG		Reactome
	Neuroactive ligand-receptor interaction Hormone signaling Estrogen signaling pathway Morphine addiction		Opioid Signalling G-protein activation Peptide ligand-binding receptors G alpha (i) signalling events Interleukin-4 and Interleukin-13 signaling

468

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Opioid dependence, susceptibility to, 1	drug response; Uncertain significance	rs1799971	RCV000010146
Tramadol response	drug response; Uncertain significance; Benign; Likely benign	rs1799971, rs17174794, rs677830, rs1583105193, rs1326499420, rs115788842, rs1583105350, rs1583105355, rs1583105431, rs1583105433, rs1583105465, rs1583105485, rs1583105621, rs1368893702, rs1583105642 View all (450 more)	RCV001029180 RCV001029134 RCV001029069 RCV001028406 RCV001028405 RCV001028404 RCV001028403 RCV001028402 RCV001028401 RCV001028400 RCV001028399 RCV001028398 RCV001028397 RCV001028396 RCV001028395 RCV001028394 RCV001028393 RCV001028392 RCV001029209 RCV001029208 RCV001029207 RCV001029206 RCV001029205 RCV001029204 RCV001029203 RCV001029202 RCV001029201 RCV001029200 RCV001029199 RCV001029198 RCV001029197 RCV001029196 RCV001029195 RCV001029194 RCV001028391 RCV001028390 RCV001028389 RCV001028388 RCV001028387 RCV001028386 RCV001028385 RCV001028384 RCV001028383 RCV001028382 RCV001028381 RCV001028380 RCV001028379 RCV001028378 RCV001028377 RCV001028376 RCV001029193 RCV001029192 RCV001029191 RCV001029190 RCV001029189 RCV001029188 RCV001029187 RCV001029186 RCV001029185 RCV001029184 RCV001029183 RCV001029182 RCV001029181 RCV001029179 RCV001029178 RCV001028375 RCV001028374 RCV001028373 RCV001028372 RCV001028371 RCV001028370 RCV001028369 RCV001028368 RCV001028367 RCV001028366 RCV001028365 RCV001028364 RCV001028363 RCV001028362 RCV001029177 RCV001029176 RCV001029175 RCV001029174 RCV001029173 RCV001029172 RCV001029171 RCV001029170 RCV001029169 RCV001029168 RCV001029167 RCV001029166 RCV001029165 RCV001029164 RCV001028361 RCV001028360 RCV001028359 RCV001028358 RCV001028357 RCV001028356 RCV001028355 RCV001028354 RCV001028353 RCV001028352 RCV001028351 RCV001028350 RCV001028349 RCV001028348 RCV001028347 RCV001029163 RCV001029162 RCV001029161 RCV001029160 RCV001029159 RCV001029158 RCV001029157 RCV001029156 RCV001029155 RCV001029154 RCV001029153 RCV001029152 RCV001029151 RCV001029150 RCV001028346 RCV001028345 RCV001028344 RCV001028343 RCV001028342 RCV001028341 RCV001028340 RCV001028339 RCV001028338 RCV001028337 RCV001028336 RCV001028335 RCV001028334 RCV001028333 RCV001028332 RCV001028331 RCV001029149 RCV001029148 RCV001029147 RCV001029146 RCV001029145 RCV001029144 RCV001029143 RCV001029142 RCV001029141 RCV001029140 RCV001029139 RCV001029138 RCV001029137 RCV001029136 RCV001029135 RCV001028330 RCV001028329 RCV001028328 RCV001028327 RCV001028326 RCV001028325 RCV001028324 RCV001028323 RCV001028322 RCV001028321 RCV001028320 RCV001028319 RCV001028318 RCV001028317 RCV001028316 RCV001028315 RCV001029133 RCV001029132 RCV001029131 RCV001029130 RCV001029129 RCV001029128 RCV001029127 RCV001029126 RCV001029125 RCV001029124 RCV001029123 RCV001029122 RCV001029121 RCV001029120 RCV001029119 RCV001029118 RCV001028314 RCV001028313 RCV001028312 RCV001028311 RCV001028310 RCV001028309 RCV001028308 RCV001028307 RCV001028306 RCV001028305 RCV001028304 RCV001028303 RCV001028302 RCV001028301 RCV001028300 RCV001028299 RCV001029117 RCV001029116 RCV001029115 RCV001029114 RCV001029113 RCV001029112 RCV001029111 RCV001029110 RCV001029109 RCV001029108 RCV001029107 RCV001029106 RCV001029105 RCV001029104 RCV001029103 RCV001029102 RCV001028298 RCV001028297 RCV001028296 RCV001028295 RCV001028294 RCV001028293 RCV001028292 RCV001028291 RCV001028290 RCV001028289 RCV001028288 RCV001028287 RCV001028286 RCV001028285 RCV001028284 RCV001028283 RCV001029101 RCV001029100 RCV001029099 RCV001029098 RCV001029097 RCV001029096 RCV001029095 RCV001029094 RCV001029093 RCV001029092 RCV001029091 RCV001029090 RCV001029089 RCV001029088 RCV001029087 RCV001029086 RCV001028282 RCV001028281 RCV001028280 RCV001028279 RCV001028278 RCV001028277 RCV001028276 RCV001028275 RCV001028274 RCV001028273 RCV001028272 RCV001028271 RCV001028270 RCV001028269 RCV001028268 RCV001028267 RCV001029085 RCV001029084 RCV001029083 RCV001029082 RCV001029081 RCV001029080 RCV001029079 RCV001029078 RCV001029077 RCV001029076 RCV001029075 RCV001029074 RCV001029073 RCV001029072 RCV001029071 RCV001029070 RCV001028266 RCV001028265 RCV001028264 RCV001028263 RCV001028262 RCV001028261 RCV001028260 RCV001028259 RCV001028258 RCV001028257 RCV001028256 RCV001028255 RCV001028254 RCV001028253 RCV001028252 RCV001028251 RCV001029068 RCV001029067 RCV001029066 RCV001029065 RCV001029064 RCV001029063 RCV001029062 RCV001029061 RCV001029060 RCV001029059 RCV001029058 RCV001029057 RCV001029056 RCV001029055 RCV001029054 RCV001028250 RCV001028249 RCV001028248 RCV001028247 RCV001028246 RCV001028245 RCV001028244 RCV001028243 RCV001028242 RCV001028241 RCV001028240 RCV001028239 RCV001028238 RCV001028237 RCV001028236 RCV001029053 RCV001029052 RCV001029051 RCV001029050 RCV001029049 RCV001029048 RCV001029047 RCV001029046 RCV001029045 RCV001029044 RCV001029043 RCV001029042 RCV001029041 RCV001029040 RCV001029039 RCV001029038 RCV001028235 RCV001028234 RCV001028233 RCV001028232 RCV001028231 RCV001028230 RCV001028229 RCV001028228 RCV001028227 RCV001028226 RCV001028225 RCV001028224 RCV001028223 RCV001028222 RCV001028221 RCV001028220 RCV001029037 RCV001029036 RCV001029035 RCV001029034 RCV001029033 RCV001029032 RCV001029031 RCV001029030 RCV001029029 RCV001029028 RCV001029027 RCV001029026 RCV001029025 RCV001029024 RCV001029023 RCV001029022 RCV001028219 RCV001028218 RCV001028217 RCV001028216 RCV001028215 RCV001028214 RCV001028213 RCV001028212 RCV001028211 RCV001028210 RCV001028209 RCV001028208 RCV001028207 RCV001028206 RCV001028205 RCV001028204 RCV001029021 RCV001029020 RCV001029019 RCV001029018 RCV001029017 RCV001029016 RCV001029015 RCV001029014 RCV001029013 RCV001029012 RCV001029011 RCV001029009 RCV001029010 RCV001029008 RCV001029007 RCV001029006 RCV001028203 RCV001028202 RCV001028201 RCV001028200 RCV001028199 RCV001028198 RCV001028197 RCV001028196 RCV001028195 RCV001028194 RCV001028193 RCV001028192 RCV001028191 RCV001028190 RCV001028189 RCV001028188 RCV001029005 RCV001029004 RCV001029003 RCV001029002 RCV001029001 RCV001029000 RCV001028999 RCV001028998 RCV001028997 RCV001028996 RCV001028995 RCV001028994 RCV001028993 RCV001028992 RCV001028991 RCV001028990 RCV001028187 RCV001028186 RCV001028185 RCV001028184 RCV001028183 RCV001028182 RCV001028181 RCV001028180 RCV001028179 RCV001028178 RCV001028177 RCV001028176 RCV001028175 RCV001028174 RCV001028173 RCV001028989 RCV001028988 RCV001028987 RCV001028986 RCV001028984 RCV001028983 RCV001028982 RCV001028981 RCV001028980 RCV001028979 RCV001028978

Show/Hide Text Mining Associations (99)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acute Pain	Associate	24884878
Alcohol Related Disorders	Associate	26228411
Alcohol Withdrawal Delirium	Associate	30085428
Alcoholism	Associate	19736238, 27109624, 30085428
Alzheimer Disease	Associate	30152845
Anxiety	Associate	30656852, 31553235
Asthma	Associate	36395102
Atherosclerosis	Associate	25613305
Attention Deficit Disorder with Hyperactivity	Associate	22841130
Binge Drinking	Associate	22143634
Binge Eating Disorder	Associate	19282821
Breast Neoplasms	Associate	25239082, 25618602, 35727214, 36672750, 36942908
Cancer Pain	Associate	17156920, 23803057, 28346387, 30700073, 35710811
Carcinoma Non Small Cell Lung	Associate	22003224
Carcinoma Pancreatic Ductal	Associate	27682590
Cerebral Small Vessel Diseases	Associate	25613305
Cholestasis	Associate	18709298
Chronic Pain	Associate	23803057, 30700073, 32098316, 36672750, 36942908
Colorectal Neoplasms	Associate	35983971, 37217861
Compulsive Personality Disorder	Associate	35960604
Constipation	Associate	36942908
Cystitis Interstitial	Associate	30973927
Dental Caries	Associate	30973902
Depressive Disorder	Associate	26228411, 30656852, 31553235, 32492095
Disorders of Excessive Somnolence	Associate	34871222
Disruptive Impulse Control and Conduct Disorders	Associate	31553235
Drug Fever	Stimulate	35182225
Drug Overdose	Associate	23318993
Drug Related Side Effects and Adverse Reactions	Associate	36988399
Dyskinesia Drug Induced	Associate	34599261
Dyslexia	Associate	37667328
Dysmenorrhea	Associate	28057931
Encephalitis	Associate	24413261, 27400929
Endometriosis	Associate	28256208
Fibromyalgia	Associate	29486785, 32098316, 33064887, 36342939
Food Addiction	Associate	23670889
Gambling	Associate	31553235
Glioma	Associate	33315125
Headache	Associate	22752568
Heart Arrest	Associate	23318993
HIV Infections	Associate	22457278, 24413261, 27400929
Idiopathic Noncirrhotic Portal Hypertension	Associate	19736238
Inflammation	Associate	16299031
Inflammation	Inhibit	31801206
Inflammatory Bowel Diseases	Associate	16299031
Intervertebral disc disease	Associate	22815498
Intervertebral Disc Displacement	Associate	22815498, 24884878
Intestinal Neoplasms	Associate	31773688
Irritable Bowel Syndrome	Stimulate	31336406
Leukemia	Associate	28650467
Liver Cirrhosis Biliary	Associate	18709298
Low Back Pain	Associate	22815498
Lung Neoplasms	Associate	22003224, 24662916, 24920011, 30455395
Lymphatic Metastasis	Associate	35983971
Melanoma	Associate	17897634, 29577418
Mental Disorders	Associate	31553235, 32492095, 9790747
Microcephaly cervical spine fusion anomalies	Associate	25266679
Migraine Disorders	Associate	22752568
Motor Disorders	Associate	25842347
Muscle Hypertonia	Associate	34971656
Musculoskeletal Pain	Associate	25842347
Neonatal Abstinence Syndrome	Associate	34971656
Neoplasm Metastasis	Associate	28346387
Neoplasms	Associate	24104703, 24662916, 24920011, 25618602, 30229370, 32900505, 33848569, 35182225, 35983971
Neoplasms Adipose Tissue	Associate	23917806
Neurocognitive Disorders	Associate	24413261
Neuropathy Painful	Associate	21837673
Neurotoxicity Syndromes	Associate	23963862
Obesity	Associate	19008867, 23917806, 29662095
Opioid Related Disorders	Associate	23318993, 31246565, 32492095
Osteoarthritis	Associate	32098316
Ovarian Diseases	Associate	16815388
Ovarian Neoplasms	Associate	35033381, 36988399
Pain	Associate	17156920, 20003118, 22752568, 22815498, 23318993, 23803057, 24884878, 25239082, 25308352, 25618602, 25842347, 26945673, 28057931, 30973927, 31755291 View all (9 more)
Pain Postoperative	Associate	20003118, 31773688, 40331998
Pancreatic Neoplasms	Associate	27682590
Parkinson Disease	Associate	35960604
Periodontitis	Associate	30973902, 36395102
Postoperative Hemorrhage	Associate	31773688
Precursor Cell Lymphoblastic Leukemia Lymphoma	Stimulate	28650467
Prostatic Neoplasms	Associate	24104703
Pruritus	Associate	18709298
Respiratory Insufficiency	Associate	23318993, 25266679
Rhinitis Atrophic	Associate	35299869
Schizophrenia	Associate	28548579
Sciatica	Associate	22815498
Seizures	Associate	30085428
Shoulder Pain	Associate	35727214, 36672750
Sleep Wake Disorders	Associate	30700073
Smoke Inhalation Injury	Associate	30973902
Social Communication Disorder	Associate	30656852
Squamous Cell Carcinoma of Head and Neck	Associate	32900505
Stomach Neoplasms	Associate	31773688
Stress Disorders Post Traumatic	Associate	22143634
Substance Related Disorders	Associate	18384978, 21070507, 22841130, 25308352, 31246565, 38118075, 9790747
Tooth Loss	Associate	30973902
Tourette Syndrome	Associate	36674940
Weight Gain	Associate	29662095
Wounds and Injuries	Associate	25842347

OPRM1 (opioid receptor mu 1)