NFATC3 (nuclear factor of activated T cells 3)

Gene

• Entrez ID: 4775
• Gene name: Nuclear factor of activated T cells 3
• Gene symbol: NFATC3
• Synonyms (NCBI Gene): NF-AT4c, NFAT4, NFATX, n339260
• Chromosome: 16
• Chromosome location: 16q22.1
• Summary: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021368	hsa-miR-9-5p	Microarray	17612493
MIRT052288	hsa-let-7b-5p	CLASH	23622248
MIRT042979	hsa-miR-324-3p	CLASH	23622248
MIRT038275	hsa-miR-361-3p	CLASH	23622248
MIRT284753	hsa-miR-185-5p	Luciferase reporter assay, qRT-PCR, Western blot	24014023
MIRT438272	hsa-miR-320a	Luciferase reporter assay, qRT-PCR, Western blot	25159093
MIRT438272	hsa-miR-320a	Luciferase reporter assay, qRT-PCR, Western blot	25159093
MIRT438272	hsa-miR-320a	Luciferase reporter assay, qRT-PCR, Western blot	25159093
MIRT438272	hsa-miR-320a	Luciferase reporter assay, qRT-PCR, Western blot	25159093
MIRT566645	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT075202	hsa-miR-548n	PAR-CLIP	20371350
MIRT566644	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT566643	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT075201	hsa-miR-548l	PAR-CLIP	20371350
MIRT566642	hsa-miR-3163	PAR-CLIP	20371350
MIRT343790	hsa-miR-7975	PAR-CLIP	20371350
MIRT440120	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440120	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT284753	hsa-miR-185-5p	Luciferase reporter assay, qRT-PCR, Western blot	25767890
MIRT732848	hsa-miR-23b-3p	Immunohistochemistry (IHC), Immunoprecipitaion (IP), Luciferase reporter assay, qRT-PCR, Western blotting	33840258
MIRT566645	hsa-miR-548e-5p	PAR-CLIP	20371350
MIRT075202	hsa-miR-548n	PAR-CLIP	20371350
MIRT566644	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT566643	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT075201	hsa-miR-548l	PAR-CLIP	20371350
MIRT566642	hsa-miR-3163	PAR-CLIP	20371350
MIRT343790	hsa-miR-7975	PAR-CLIP	20371350
MIRT1182252	hsa-miR-1200	CLIP-seq
MIRT1182253	hsa-miR-1226	CLIP-seq
MIRT1182254	hsa-miR-1229	CLIP-seq
MIRT1182255	hsa-miR-146a	CLIP-seq
MIRT1182256	hsa-miR-146b-5p	CLIP-seq
MIRT1182257	hsa-miR-15a	CLIP-seq
MIRT1182258	hsa-miR-15b	CLIP-seq
MIRT1182259	hsa-miR-16	CLIP-seq
MIRT1182260	hsa-miR-195	CLIP-seq
MIRT1182261	hsa-miR-199a-5p	CLIP-seq
MIRT1182262	hsa-miR-199b-5p	CLIP-seq
MIRT1182263	hsa-miR-25	CLIP-seq
MIRT1182264	hsa-miR-302a	CLIP-seq
MIRT1182265	hsa-miR-302b	CLIP-seq
MIRT1182266	hsa-miR-302c	CLIP-seq
MIRT1182267	hsa-miR-302d	CLIP-seq
MIRT1182268	hsa-miR-302e	CLIP-seq
MIRT1182269	hsa-miR-3065-3p	CLIP-seq
MIRT1182270	hsa-miR-30a	CLIP-seq
MIRT1182271	hsa-miR-30b	CLIP-seq
MIRT1182272	hsa-miR-30c	CLIP-seq
MIRT1182273	hsa-miR-30d	CLIP-seq
MIRT1182274	hsa-miR-30e	CLIP-seq
MIRT1182275	hsa-miR-32	CLIP-seq
MIRT1182276	hsa-miR-3607-3p	CLIP-seq
MIRT1182277	hsa-miR-3614-3p	CLIP-seq
MIRT1182278	hsa-miR-363	CLIP-seq
MIRT1182279	hsa-miR-367	CLIP-seq
MIRT1182280	hsa-miR-372	CLIP-seq
MIRT1182281	hsa-miR-373	CLIP-seq
MIRT1182282	hsa-miR-421	CLIP-seq
MIRT1182283	hsa-miR-424	CLIP-seq
MIRT1182284	hsa-miR-4251	CLIP-seq
MIRT1182285	hsa-miR-4261	CLIP-seq
MIRT1182286	hsa-miR-4297	CLIP-seq
MIRT1182287	hsa-miR-4324	CLIP-seq
MIRT1182288	hsa-miR-4530	CLIP-seq
MIRT1182289	hsa-miR-4708-3p	CLIP-seq
MIRT1182290	hsa-miR-4709-5p	CLIP-seq
MIRT1182291	hsa-miR-4718	CLIP-seq
MIRT1182292	hsa-miR-4733-3p	CLIP-seq
MIRT1182293	hsa-miR-4793-5p	CLIP-seq
MIRT1182294	hsa-miR-4803	CLIP-seq
MIRT1182295	hsa-miR-497	CLIP-seq
MIRT1182296	hsa-miR-505	CLIP-seq
MIRT1182297	hsa-miR-512-3p	CLIP-seq
MIRT1182298	hsa-miR-520a-3p	CLIP-seq
MIRT1182299	hsa-miR-520b	CLIP-seq
MIRT1182300	hsa-miR-520c-3p	CLIP-seq
MIRT1182301	hsa-miR-520d-3p	CLIP-seq
MIRT1182302	hsa-miR-520e	CLIP-seq
MIRT1182303	hsa-miR-544b	CLIP-seq
MIRT1182304	hsa-miR-548u	CLIP-seq
MIRT1182305	hsa-miR-589	CLIP-seq
MIRT1182306	hsa-miR-634	CLIP-seq
MIRT1182307	hsa-miR-92a	CLIP-seq
MIRT1182308	hsa-miR-92b	CLIP-seq
MIRT1182309	hsa-miR-1	CLIP-seq
MIRT1182310	hsa-miR-105	CLIP-seq
MIRT1182311	hsa-miR-1197	CLIP-seq
MIRT1182253	hsa-miR-1226	CLIP-seq
MIRT1182254	hsa-miR-1229	CLIP-seq
MIRT1182312	hsa-miR-1291	CLIP-seq
MIRT1182313	hsa-miR-1299	CLIP-seq
MIRT1182314	hsa-miR-1305	CLIP-seq
MIRT1182257	hsa-miR-15a	CLIP-seq
MIRT1182258	hsa-miR-15b	CLIP-seq
MIRT1182259	hsa-miR-16	CLIP-seq
MIRT1182315	hsa-miR-1827	CLIP-seq
MIRT1182260	hsa-miR-195	CLIP-seq
MIRT1182316	hsa-miR-206	CLIP-seq
MIRT1182317	hsa-miR-27a	CLIP-seq
MIRT1182318	hsa-miR-27b	CLIP-seq
MIRT1182319	hsa-miR-296-5p	CLIP-seq
MIRT1182320	hsa-miR-29a	CLIP-seq
MIRT1182321	hsa-miR-29b	CLIP-seq
MIRT1182322	hsa-miR-29c	CLIP-seq
MIRT1182269	hsa-miR-3065-3p	CLIP-seq
MIRT1182323	hsa-miR-3119	CLIP-seq
MIRT1182324	hsa-miR-3145-3p	CLIP-seq
MIRT1182325	hsa-miR-3158-3p	CLIP-seq
MIRT1182326	hsa-miR-3173-5p	CLIP-seq
MIRT1182327	hsa-miR-3176	CLIP-seq
MIRT1182328	hsa-miR-3187-3p	CLIP-seq
MIRT1182329	hsa-miR-3188	CLIP-seq
MIRT1182330	hsa-miR-326	CLIP-seq
MIRT1182331	hsa-miR-330-3p	CLIP-seq
MIRT1182332	hsa-miR-330-5p	CLIP-seq
MIRT1182333	hsa-miR-3650	CLIP-seq
MIRT1182334	hsa-miR-3671	CLIP-seq
MIRT1182335	hsa-miR-3673	CLIP-seq
MIRT1182336	hsa-miR-3680	CLIP-seq
MIRT1182337	hsa-miR-370	CLIP-seq
MIRT1182338	hsa-miR-376a	CLIP-seq
MIRT1182339	hsa-miR-376b	CLIP-seq
MIRT1182340	hsa-miR-377	CLIP-seq
MIRT1182341	hsa-miR-3911	CLIP-seq
MIRT1182342	hsa-miR-3922-3p	CLIP-seq
MIRT1182283	hsa-miR-424	CLIP-seq
MIRT1182343	hsa-miR-4265	CLIP-seq
MIRT1182344	hsa-miR-4296	CLIP-seq
MIRT1182345	hsa-miR-4299	CLIP-seq
MIRT1182346	hsa-miR-4303	CLIP-seq
MIRT1182347	hsa-miR-4312	CLIP-seq
MIRT1182348	hsa-miR-4322	CLIP-seq
MIRT1182349	hsa-miR-4417	CLIP-seq
MIRT1182350	hsa-miR-4422	CLIP-seq
MIRT1182351	hsa-miR-4436a	CLIP-seq
MIRT1182352	hsa-miR-4456	CLIP-seq
MIRT1182353	hsa-miR-4504	CLIP-seq
MIRT1182354	hsa-miR-450b-3p	CLIP-seq
MIRT1182355	hsa-miR-4520a-3p	CLIP-seq
MIRT1182356	hsa-miR-4520b-3p	CLIP-seq
MIRT1182357	hsa-miR-4523	CLIP-seq
MIRT1182358	hsa-miR-4529-5p	CLIP-seq
MIRT1182288	hsa-miR-4530	CLIP-seq
MIRT1182359	hsa-miR-4643	CLIP-seq
MIRT1182360	hsa-miR-4649-3p	CLIP-seq
MIRT1182361	hsa-miR-4688	CLIP-seq
MIRT1182362	hsa-miR-4711-3p	CLIP-seq
MIRT1182363	hsa-miR-4728-3p	CLIP-seq
MIRT1182364	hsa-miR-4731-5p	CLIP-seq
MIRT1182292	hsa-miR-4733-3p	CLIP-seq
MIRT1182365	hsa-miR-4749-3p	CLIP-seq
MIRT1182366	hsa-miR-4755-3p	CLIP-seq
MIRT1182367	hsa-miR-4762-3p	CLIP-seq
MIRT1182368	hsa-miR-4768-5p	CLIP-seq
MIRT1182295	hsa-miR-497	CLIP-seq
MIRT1182369	hsa-miR-498	CLIP-seq
MIRT1182296	hsa-miR-505	CLIP-seq
MIRT1182370	hsa-miR-511	CLIP-seq
MIRT1182371	hsa-miR-513a-5p	CLIP-seq
MIRT1182372	hsa-miR-526b	CLIP-seq
MIRT1182373	hsa-miR-542-3p	CLIP-seq
MIRT1182374	hsa-miR-544	CLIP-seq
MIRT1182375	hsa-miR-548q	CLIP-seq
MIRT1182376	hsa-miR-548t	CLIP-seq
MIRT1182377	hsa-miR-591	CLIP-seq
MIRT1182378	hsa-miR-596	CLIP-seq
MIRT1182379	hsa-miR-607	CLIP-seq
MIRT1182380	hsa-miR-613	CLIP-seq
MIRT1182381	hsa-miR-628-5p	CLIP-seq
MIRT1182306	hsa-miR-634	CLIP-seq
MIRT1182382	hsa-miR-642b	CLIP-seq
MIRT1182383	hsa-miR-769-3p	CLIP-seq
MIRT1182384	hsa-miR-875-3p	CLIP-seq
MIRT1182385	hsa-miR-888	CLIP-seq
MIRT1182386	hsa-miR-9	CLIP-seq
MIRT1182292	hsa-miR-4733-3p	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1922285	hsa-miR-493	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1182309	hsa-miR-1	CLIP-seq
MIRT2052885	hsa-miR-1178	CLIP-seq
MIRT1182252	hsa-miR-1200	CLIP-seq
MIRT1182253	hsa-miR-1226	CLIP-seq
MIRT1182254	hsa-miR-1229	CLIP-seq
MIRT1182312	hsa-miR-1291	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1182313	hsa-miR-1299	CLIP-seq
MIRT1182314	hsa-miR-1305	CLIP-seq
MIRT2052886	hsa-miR-148a	CLIP-seq
MIRT2052887	hsa-miR-148b	CLIP-seq
MIRT2052888	hsa-miR-152	CLIP-seq
MIRT2052889	hsa-miR-153	CLIP-seq
MIRT2052890	hsa-miR-154	CLIP-seq
MIRT1182257	hsa-miR-15a	CLIP-seq
MIRT1182258	hsa-miR-15b	CLIP-seq
MIRT1182259	hsa-miR-16	CLIP-seq
MIRT1182260	hsa-miR-195	CLIP-seq
MIRT1182316	hsa-miR-206	CLIP-seq
MIRT2052891	hsa-miR-2115	CLIP-seq
MIRT2052892	hsa-miR-216a	CLIP-seq
MIRT2052893	hsa-miR-221	CLIP-seq
MIRT2052894	hsa-miR-222	CLIP-seq
MIRT1182319	hsa-miR-296-5p	CLIP-seq
MIRT1182320	hsa-miR-29a	CLIP-seq
MIRT1182321	hsa-miR-29b	CLIP-seq
MIRT1182322	hsa-miR-29c	CLIP-seq
MIRT1182264	hsa-miR-302a	CLIP-seq
MIRT1182265	hsa-miR-302b	CLIP-seq
MIRT1182266	hsa-miR-302c	CLIP-seq
MIRT1182267	hsa-miR-302d	CLIP-seq
MIRT1182268	hsa-miR-302e	CLIP-seq
MIRT1182269	hsa-miR-3065-3p	CLIP-seq
MIRT2052895	hsa-miR-3134	CLIP-seq
MIRT2052896	hsa-miR-3140-5p	CLIP-seq
MIRT2052897	hsa-miR-3150b-3p	CLIP-seq
MIRT2052898	hsa-miR-3173-3p	CLIP-seq
MIRT2052899	hsa-miR-320b	CLIP-seq
MIRT2052900	hsa-miR-320c	CLIP-seq
MIRT2052901	hsa-miR-320d	CLIP-seq
MIRT2052902	hsa-miR-325	CLIP-seq
MIRT1182331	hsa-miR-330-3p	CLIP-seq
MIRT2052903	hsa-miR-342-3p	CLIP-seq
MIRT2052904	hsa-miR-34c-3p	CLIP-seq
MIRT1182276	hsa-miR-3607-3p	CLIP-seq
MIRT2052905	hsa-miR-3613-3p	CLIP-seq
MIRT2052906	hsa-miR-3622a-3p	CLIP-seq
MIRT2052907	hsa-miR-3622a-5p	CLIP-seq
MIRT2052908	hsa-miR-3622b-3p	CLIP-seq
MIRT1182333	hsa-miR-3650	CLIP-seq
MIRT1182335	hsa-miR-3673	CLIP-seq
MIRT1182336	hsa-miR-3680	CLIP-seq
MIRT2052909	hsa-miR-3691-3p	CLIP-seq
MIRT1182337	hsa-miR-370	CLIP-seq
MIRT2052910	hsa-miR-371b-5p	CLIP-seq
MIRT1182280	hsa-miR-372	CLIP-seq
MIRT1182281	hsa-miR-373	CLIP-seq
MIRT1182340	hsa-miR-377	CLIP-seq
MIRT2052911	hsa-miR-3910	CLIP-seq
MIRT1182341	hsa-miR-3911	CLIP-seq
MIRT2052912	hsa-miR-411	CLIP-seq
MIRT1182283	hsa-miR-424	CLIP-seq
MIRT1182285	hsa-miR-4261	CLIP-seq
MIRT2052913	hsa-miR-4282	CLIP-seq
MIRT1182350	hsa-miR-4422	CLIP-seq
MIRT2052914	hsa-miR-4423-3p	CLIP-seq
MIRT2052915	hsa-miR-4428	CLIP-seq
MIRT2052916	hsa-miR-4429	CLIP-seq
MIRT1182351	hsa-miR-4436a	CLIP-seq
MIRT2052917	hsa-miR-4438	CLIP-seq
MIRT2052918	hsa-miR-4473	CLIP-seq
MIRT1182355	hsa-miR-4520a-3p	CLIP-seq
MIRT1182356	hsa-miR-4520b-3p	CLIP-seq
MIRT1182288	hsa-miR-4530	CLIP-seq
MIRT2052919	hsa-miR-4534	CLIP-seq
MIRT2052920	hsa-miR-4661-5p	CLIP-seq
MIRT2052921	hsa-miR-4678	CLIP-seq
MIRT2052922	hsa-miR-4686	CLIP-seq
MIRT2052923	hsa-miR-4689	CLIP-seq
MIRT2052924	hsa-miR-4698	CLIP-seq
MIRT1182362	hsa-miR-4711-3p	CLIP-seq
MIRT2052925	hsa-miR-4711-5p	CLIP-seq
MIRT1182292	hsa-miR-4733-3p	CLIP-seq
MIRT2052926	hsa-miR-4761-5p	CLIP-seq
MIRT2052927	hsa-miR-4762-5p	CLIP-seq
MIRT2052928	hsa-miR-4782-5p	CLIP-seq
MIRT2052929	hsa-miR-4784	CLIP-seq
MIRT1922285	hsa-miR-493	CLIP-seq
MIRT1182295	hsa-miR-497	CLIP-seq
MIRT1182369	hsa-miR-498	CLIP-seq
MIRT2052930	hsa-miR-5095	CLIP-seq
MIRT1182370	hsa-miR-511	CLIP-seq
MIRT1182297	hsa-miR-512-3p	CLIP-seq
MIRT2052931	hsa-miR-516a-3p	CLIP-seq
MIRT1182298	hsa-miR-520a-3p	CLIP-seq
MIRT1182299	hsa-miR-520b	CLIP-seq
MIRT1182300	hsa-miR-520c-3p	CLIP-seq
MIRT1182301	hsa-miR-520d-3p	CLIP-seq
MIRT2052932	hsa-miR-520d-5p	CLIP-seq
MIRT1182302	hsa-miR-520e	CLIP-seq
MIRT2052933	hsa-miR-520f	CLIP-seq
MIRT2052934	hsa-miR-524-5p	CLIP-seq
MIRT2052935	hsa-miR-548a-3p	CLIP-seq
MIRT2052936	hsa-miR-548e	CLIP-seq
MIRT2052937	hsa-miR-548f	CLIP-seq
MIRT2052938	hsa-miR-548v	CLIP-seq
MIRT1182378	hsa-miR-596	CLIP-seq
MIRT1182380	hsa-miR-613	CLIP-seq
MIRT1182306	hsa-miR-634	CLIP-seq
MIRT1182382	hsa-miR-642b	CLIP-seq
MIRT2052939	hsa-miR-760	CLIP-seq
MIRT1182385	hsa-miR-888	CLIP-seq
MIRT1182386	hsa-miR-9	CLIP-seq
MIRT2052885	hsa-miR-1178	CLIP-seq
MIRT1182252	hsa-miR-1200	CLIP-seq
MIRT2282107	hsa-miR-1245	CLIP-seq
MIRT2282108	hsa-miR-1264	CLIP-seq
MIRT2282109	hsa-miR-128	CLIP-seq
MIRT2282110	hsa-miR-1283	CLIP-seq
MIRT1182313	hsa-miR-1299	CLIP-seq
MIRT2052886	hsa-miR-148a	CLIP-seq
MIRT2052887	hsa-miR-148b	CLIP-seq
MIRT2052888	hsa-miR-152	CLIP-seq
MIRT1182257	hsa-miR-15a	CLIP-seq
MIRT1182258	hsa-miR-15b	CLIP-seq
MIRT1182259	hsa-miR-16	CLIP-seq
MIRT2282111	hsa-miR-1913	CLIP-seq
MIRT1182260	hsa-miR-195	CLIP-seq
MIRT2282112	hsa-miR-2110	CLIP-seq
MIRT2052891	hsa-miR-2115	CLIP-seq
MIRT1182320	hsa-miR-29a	CLIP-seq
MIRT1182321	hsa-miR-29b	CLIP-seq
MIRT1182322	hsa-miR-29c	CLIP-seq
MIRT1182264	hsa-miR-302a	CLIP-seq
MIRT1182265	hsa-miR-302b	CLIP-seq
MIRT1182266	hsa-miR-302c	CLIP-seq
MIRT1182267	hsa-miR-302d	CLIP-seq
MIRT1182268	hsa-miR-302e	CLIP-seq
MIRT1182269	hsa-miR-3065-3p	CLIP-seq
MIRT2052896	hsa-miR-3140-5p	CLIP-seq
MIRT2282113	hsa-miR-3185	CLIP-seq
MIRT2052902	hsa-miR-325	CLIP-seq
MIRT2282114	hsa-miR-340	CLIP-seq
MIRT1182276	hsa-miR-3607-3p	CLIP-seq
MIRT2052905	hsa-miR-3613-3p	CLIP-seq
MIRT2052906	hsa-miR-3622a-3p	CLIP-seq
MIRT2052908	hsa-miR-3622b-3p	CLIP-seq
MIRT2052909	hsa-miR-3691-3p	CLIP-seq
MIRT1182280	hsa-miR-372	CLIP-seq
MIRT1182281	hsa-miR-373	CLIP-seq
MIRT1182340	hsa-miR-377	CLIP-seq
MIRT2282115	hsa-miR-3974	CLIP-seq
MIRT2052912	hsa-miR-411	CLIP-seq
MIRT1182283	hsa-miR-424	CLIP-seq
MIRT1182284	hsa-miR-4251	CLIP-seq
MIRT1182285	hsa-miR-4261	CLIP-seq
MIRT2282116	hsa-miR-4271	CLIP-seq
MIRT2282117	hsa-miR-4314	CLIP-seq
MIRT1182350	hsa-miR-4422	CLIP-seq
MIRT2282118	hsa-miR-4457	CLIP-seq
MIRT2282119	hsa-miR-4641	CLIP-seq
MIRT2282120	hsa-miR-4667-5p	CLIP-seq
MIRT2282121	hsa-miR-4668-5p	CLIP-seq
MIRT2282122	hsa-miR-4676-5p	CLIP-seq
MIRT2052922	hsa-miR-4686	CLIP-seq
MIRT2282123	hsa-miR-4700-5p	CLIP-seq
MIRT2052925	hsa-miR-4711-5p	CLIP-seq
MIRT2282124	hsa-miR-4725-3p	CLIP-seq
MIRT1182363	hsa-miR-4728-3p	CLIP-seq
MIRT2282125	hsa-miR-4731-3p	CLIP-seq
MIRT1182292	hsa-miR-4733-3p	CLIP-seq
MIRT1182368	hsa-miR-4768-5p	CLIP-seq
MIRT2282126	hsa-miR-4773	CLIP-seq
MIRT2282127	hsa-miR-4801	CLIP-seq
MIRT2282128	hsa-miR-4802-5p	CLIP-seq
MIRT1182295	hsa-miR-497	CLIP-seq
MIRT1182297	hsa-miR-512-3p	CLIP-seq
MIRT2052931	hsa-miR-516a-3p	CLIP-seq
MIRT2282129	hsa-miR-516b	CLIP-seq
MIRT1182298	hsa-miR-520a-3p	CLIP-seq
MIRT1182299	hsa-miR-520b	CLIP-seq
MIRT1182300	hsa-miR-520c-3p	CLIP-seq
MIRT1182301	hsa-miR-520d-3p	CLIP-seq
MIRT2052932	hsa-miR-520d-5p	CLIP-seq
MIRT1182302	hsa-miR-520e	CLIP-seq
MIRT2052934	hsa-miR-524-5p	CLIP-seq
MIRT2282130	hsa-miR-575	CLIP-seq
MIRT2282131	hsa-miR-624	CLIP-seq
MIRT1182306	hsa-miR-634	CLIP-seq
MIRT2282132	hsa-miR-637	CLIP-seq
MIRT1182385	hsa-miR-888	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1921441	hsa-miR-129-5p	CLIP-seq
MIRT1182314	hsa-miR-1305	CLIP-seq
MIRT2580234	hsa-miR-193a-3p	CLIP-seq
MIRT2580235	hsa-miR-193b	CLIP-seq
MIRT2580236	hsa-miR-1976	CLIP-seq
MIRT2580237	hsa-miR-204	CLIP-seq
MIRT2580238	hsa-miR-211	CLIP-seq
MIRT2580239	hsa-miR-2861	CLIP-seq
MIRT1182327	hsa-miR-3176	CLIP-seq
MIRT2580240	hsa-miR-3545-3p	CLIP-seq
MIRT2580241	hsa-miR-3647-3p	CLIP-seq
MIRT1182336	hsa-miR-3680	CLIP-seq
MIRT2580242	hsa-miR-3690	CLIP-seq
MIRT1182342	hsa-miR-3922-3p	CLIP-seq
MIRT2052912	hsa-miR-411	CLIP-seq
MIRT2580243	hsa-miR-4254	CLIP-seq
MIRT2580244	hsa-miR-4267	CLIP-seq
MIRT2052913	hsa-miR-4282	CLIP-seq
MIRT2580245	hsa-miR-4287	CLIP-seq
MIRT2580246	hsa-miR-4512	CLIP-seq
MIRT2580247	hsa-miR-4539	CLIP-seq
MIRT2580248	hsa-miR-4642	CLIP-seq
MIRT2580249	hsa-miR-4685-3p	CLIP-seq
MIRT2580250	hsa-miR-4717-5p	CLIP-seq
MIRT2580251	hsa-miR-4720-5p	CLIP-seq
MIRT2580252	hsa-miR-4799-3p	CLIP-seq
MIRT1182369	hsa-miR-498	CLIP-seq
MIRT2580253	hsa-miR-541	CLIP-seq
MIRT2580254	hsa-miR-549	CLIP-seq
MIRT2580255	hsa-miR-552	CLIP-seq
MIRT1182382	hsa-miR-642b	CLIP-seq
MIRT2580256	hsa-miR-654-5p	CLIP-seq
MIRT2580234	hsa-miR-193a-3p	CLIP-seq
MIRT2580235	hsa-miR-193b	CLIP-seq
MIRT2580237	hsa-miR-204	CLIP-seq
MIRT2580238	hsa-miR-211	CLIP-seq
MIRT1182327	hsa-miR-3176	CLIP-seq
MIRT2580240	hsa-miR-3545-3p	CLIP-seq
MIRT1182342	hsa-miR-3922-3p	CLIP-seq
MIRT2052912	hsa-miR-411	CLIP-seq
MIRT2580244	hsa-miR-4267	CLIP-seq
MIRT2580245	hsa-miR-4287	CLIP-seq
MIRT2580247	hsa-miR-4539	CLIP-seq
MIRT2580249	hsa-miR-4685-3p	CLIP-seq
MIRT2580250	hsa-miR-4717-5p	CLIP-seq
MIRT2580253	hsa-miR-541	CLIP-seq
MIRT2580254	hsa-miR-549	CLIP-seq
MIRT2580255	hsa-miR-552	CLIP-seq
MIRT1182382	hsa-miR-642b	CLIP-seq
MIRT2580256	hsa-miR-654-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	15173172
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IGI	23543060
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	15173172
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	15173172
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	24330068, 28514442, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	12370307, 18815128
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005667	Component	Transcription regulator complex	IBA
GO:0005737	Component	Cytoplasm	IDA	18815128
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	TAS	7749981
GO:0006954	Process	Inflammatory response	TAS	7739550
GO:0033173	Process	Calcineurin-NFAT signaling cascade	IBA
GO:0045059	Process	Positive thymic T cell selection	ISS
GO:0045429	Process	Positive regulation of nitric oxide biosynthetic process	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	18815128
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	15173172
GO:1902894	Process	Negative regulation of miRNA transcription	IGI	23543060
GO:1904157	Process	DN4 thymocyte differentiation	ISS
GO:1905064	Process	Negative regulation of vascular associated smooth muscle cell differentiation	IDA	23853098
GO:1905653	Process	Positive regulation of artery morphogenesis	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 602698
• HGNC: 7777
• e!Ensembl: ENSG00000072736

Protein

• UniProt ID: Q12968
• Protein name: Nuclear factor of activated T-cells, cytoplasmic 3 (NF-ATc3) (NFATc3) (NFATx) (T-cell transcription factor NFAT4) (NF-AT4) (NF-AT4c)
• Protein function: Acts as a regulator of transcriptional activation. Binds to the TNFSF11/RANKL promoter region and promotes TNFSF11 transcription (By similarity). Binding to the TNFSF11 promoter region is increased by high levels of Ca(2+) which induce NFATC3 ex
• PDB: 2XRW, 2XS0
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00554	RHD_DNA_bind	433 → 592	Rel homology DNA-binding domain	Domain
  PF16179	RHD_dimer	601 → 701	Rel homology dimerisation domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: [Isoform 1]: Predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney. {ECO:0000269|PubMed:9759864}.; TISSUE SPECIFICITY: [Isoform 2]: Predominantly expressed in skeletal muscle (PubMed:9759864). Al
• Sequence:

  MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
  CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
  HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
  SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
  PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
  PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
  DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
  DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
  FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
  LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
  HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
  VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
  PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
  IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
  LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
  QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
  SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
  PNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL

• Sequence length: 1075

Pathways

KEGG:

MAPK signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Efferocytosis
Cellular senescence
Wnt signaling pathway
Axon guidance
C-type lectin receptor signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation
T cell receptor signaling pathway
B cell receptor signaling pathway
Oxytocin signaling pathway
Yersinia infection
Hepatitis B
Human cytomegalovirus infection
Human T-cell leukemia virus 1 infection
Kaposi sarcoma-associated herpesvirus infection
Human immunodeficiency virus 1 infection
PD-L1 expression and PD-1 checkpoint pathway in cancer
Lipid and atherosclerosis

Reactome:

Calcineurin activates NFAT
FCERI mediated Ca+2 mobilization
CLEC7A (Dectin-1) induces NFAT activation

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
GOUT	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Keratoconus	Uncertain significance	ClinVar Disgenet	★★★☆☆ Reported in Unknown/Other Associations (≥2 sources)
SCHIZOPHRENIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenocarcinoma of Lung	Associate	27058892, 34257525	★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Associate	16389460	★☆☆☆☆ Found in Text Mining only
Atrial Fibrillation	Stimulate	25422138	★☆☆☆☆ Found in Text Mining only
Atrial Remodeling	Associate	25422138	★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Stimulate	29507296	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	18668201	★☆☆☆☆ Found in Text Mining only
Bronchopulmonary Dysplasia	Associate	37060021	★☆☆☆☆ Found in Text Mining only
Calcinosis	Associate	36257194	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Associate	33520407	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	33520407	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Associate	21192845, 34257525	★☆☆☆☆ Found in Text Mining only
Carcinoma Pancreatic Ductal	Associate	35484132	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Inhibit	36257194	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Stimulate	21192845	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Inhibit	34257525	★☆☆☆☆ Found in Text Mining only
Cardiomegaly	Associate	18668201	★☆☆☆☆ Found in Text Mining only
Cognition Disorders	Associate	36737481	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	29909608	★☆☆☆☆ Found in Text Mining only
COVID 19	Associate	34723226	★☆☆☆☆ Found in Text Mining only
Esophageal Neoplasms	Associate	31519770	★☆☆☆☆ Found in Text Mining only
Glioma	Associate	34443374	★☆☆☆☆ Found in Text Mining only
Heart Valve Diseases	Stimulate	25422138	★☆☆☆☆ Found in Text Mining only
Hypoxia	Stimulate	35484132	★☆☆☆☆ Found in Text Mining only
Immune Reconstitution Inflammatory Syndrome	Stimulate	28316373	★☆☆☆☆ Found in Text Mining only
Kidney Diseases	Stimulate	22642569	★☆☆☆☆ Found in Text Mining only
Leukoencephalopathy Progressive Multifocal	Associate	26531763	★☆☆☆☆ Found in Text Mining only
Melanoma Cutaneous Malignant	Associate	31673075	★☆☆☆☆ Found in Text Mining only
Mucocutaneous Lymph Node Syndrome	Stimulate	32170198	★☆☆☆☆ Found in Text Mining only
Neoplasm Invasiveness	Associate	29909608	★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	21192845, 35484132	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	22330139, 26795951, 29909608	★☆☆☆☆ Found in Text Mining only
Neoplasms	Inhibit	27058892	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	35484132	★☆☆☆☆ Found in Text Mining only
Personality Disorders	Associate	29307746	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Associate	27242348, 29507296	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Squamous Cell Carcinoma of Head and Neck	Associate	19671684, 22330139, 33840648	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Associate	29307746	★☆☆☆☆ Found in Text Mining only
Turner Syndrome	Associate	24850140	★☆☆☆☆ Found in Text Mining only