MIR17HG (miR-17-92a-1 cluster host gene)

Gene Gene information from NCBI Gene database.
Gene miRNA Other IDs Protein Associated diseases
Entrez ID 407975
Gene name MiR-17-92a-1 cluster host gene
Gene symbol MIR17HG
Synonyms (NCBI Gene)
C13orf25LINC00048MIHG1MIRH1MIRHG1NCRNA00048miR-17-92
Chromosome 13
Chromosome location 13q31.3
Summary This gene is the host gene for the MIR17-92 cluster, a group of at least six microRNAs (miRNAs) that may be involved in cell survival, proliferation, differentiation, and angiogenesis. Amplification of this gene has been found in several lymphomas and sol
miRNA miRNA information provided by mirtarbase database.
2
Gene miRNA Other IDs Protein Associated diseases
Show/Hide all (2)
miRTarBase ID miRNA Experiments Reference
MIRT019793 hsa-miR-375 Microarray 20215506
MIRT733191 hsa-miR-374a-5p RNA-seq 33552263
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
609415 23564 ENSG00000215417
Protein Protein information from UniProt database.
Gene miRNA Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q75NE6
Protein name Putative microRNA 17 host gene protein (Putative microRNA host gene 1 protein)
Family and domains
Tissue specificity TISSUE SPECIFICITY: Highly expressed in B-cell lymphoma and lung cancer.
Sequence 
MFCHVDVKISSKRYTWTKLPLNVPKLVLIYLQSHFVLFFFSMCQSIWERPAIGRATTSSA
SWMVGYDCLL
Sequence length 70
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
20
Gene miRNA Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
MIR17HG-related disorder Uncertain significance; Likely benign; Benign rs994382198, rs778027764, rs769767106, rs535675469, rs1034074756, rs1200989960, rs149052230, rs1875410050, rs562884140, rs182442873, rs1339111235, rs549650270, rs181587881, rs139418718, rs7336610
View all (5 more)		 RCV003408656
RCV003410652
RCV003391240
RCV003408732
RCV003393164
RCV003896669
RCV003899014
RCV003894606
RCV003907248
RCV003931841
RCV003982726
RCV003893985
RCV003904424
RCV003979702
RCV003984722
RCV003911535
RCV003954312
RCV003951606
RCV003951807
RCV003974763
Show/Hide Text Mining Associations (116)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Acquired Immunodeficiency Syndrome Associate 21698185
Adenocarcinoma Associate 23466817
Adenocarcinoma Stimulate 24743967
Adenocarcinoma of Lung Associate 23036707, 37801008
Adenomatous Polyposis Coli Inhibit 26804172
Asthma Associate 31924195
Astrocytoma Associate 33430425
Ataxia Telangiectasia Associate 35710306
Atherosclerosis Associate 26956882
Azoospermia Associate 19210773