Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3996
Gene name Gene Name - the full gene name approved by the HGNC.	LLGL scribble cell polarity complex component 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LLGL1
Synonyms (NCBI Gene) Gene synonyms aliases	DLG4, HUGL, HUGL-1, HUGL1, LLGL, Lgl1, Mgl1
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17p11.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine resi

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miRTarBase ID	miRNA	Experiments	Reference
MIRT026101	hsa-miR-196a-5p	qRT-PCR	21077158
MIRT030531	hsa-miR-24-3p	Microarray	19748357
MIRT045222	hsa-miR-186-5p	CLASH	23622248
MIRT694754	hsa-miR-3929	HITS-CLIP	23313552
MIRT694753	hsa-miR-4419b	HITS-CLIP	23313552
MIRT694752	hsa-miR-4478	HITS-CLIP	23313552
MIRT670602	hsa-miR-4446-3p	HITS-CLIP	23313552
MIRT670601	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT694751	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT670600	hsa-miR-1285-3p	HITS-CLIP	23313552
MIRT670599	hsa-miR-3187-5p	HITS-CLIP	23313552
MIRT670598	hsa-miR-5189-5p	HITS-CLIP	23313552
MIRT670597	hsa-miR-612	HITS-CLIP	23313552
MIRT670596	hsa-miR-6860	HITS-CLIP	23313552
MIRT694750	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694749	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT694748	hsa-miR-7854-3p	HITS-CLIP	23313552
MIRT694747	hsa-miR-6134	HITS-CLIP	23313552
MIRT670595	hsa-miR-6132	HITS-CLIP	23313552
MIRT670594	hsa-miR-6836-5p	HITS-CLIP	23313552
MIRT694746	hsa-miR-1909-3p	HITS-CLIP	23313552
MIRT694745	hsa-miR-6722-3p	HITS-CLIP	23313552
MIRT694744	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT670593	hsa-miR-3622b-5p	HITS-CLIP	23313552
MIRT670592	hsa-miR-4284	HITS-CLIP	23313552
MIRT030531	hsa-miR-24-3p	HITS-CLIP	23313552
MIRT670591	hsa-miR-4505	HITS-CLIP	23313552
MIRT670590	hsa-miR-5787	HITS-CLIP	23313552
MIRT694743	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT694742	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT694741	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT694740	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT694739	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT694738	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT670588	hsa-miR-3945	HITS-CLIP	23313552
MIRT670589	hsa-miR-4253	HITS-CLIP	23313552
MIRT670587	hsa-miR-6862-5p	HITS-CLIP	23313552
MIRT670586	hsa-miR-4492	HITS-CLIP	23313552
MIRT670585	hsa-miR-4498	HITS-CLIP	23313552
MIRT670584	hsa-miR-5001-5p	HITS-CLIP	23313552
MIRT670583	hsa-miR-762	HITS-CLIP	23313552
MIRT694737	hsa-miR-363-5p	HITS-CLIP	23313552
MIRT694736	hsa-miR-6745	HITS-CLIP	23313552
MIRT694735	hsa-miR-6756-5p	HITS-CLIP	23313552
MIRT694734	hsa-miR-6766-5p	HITS-CLIP	23313552
MIRT694733	hsa-miR-1293	HITS-CLIP	23313552
MIRT694732	hsa-miR-4483	HITS-CLIP	23313552
MIRT694731	hsa-miR-3165	HITS-CLIP	23313552
MIRT694730	hsa-miR-6769a-5p	HITS-CLIP	23313552
MIRT694729	hsa-miR-6769b-5p	HITS-CLIP	23313552
MIRT694728	hsa-miR-6748-5p	HITS-CLIP	23313552
MIRT670582	hsa-miR-7977	HITS-CLIP	23313552
MIRT694727	hsa-miR-6511b-5p	HITS-CLIP	23313552
MIRT694726	hsa-miR-6811-5p	HITS-CLIP	23313552
MIRT694725	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT694724	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT694723	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT694722	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT694721	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT694720	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT694719	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT694718	hsa-miR-3689c	HITS-CLIP	23313552
MIRT694717	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT694716	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT670581	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT670580	hsa-miR-3122	HITS-CLIP	23313552
MIRT670579	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT670578	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT670577	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT694715	hsa-miR-665	HITS-CLIP	23313552
MIRT670602	hsa-miR-4446-3p	HITS-CLIP	23824327
MIRT670601	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT670600	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT670599	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT670598	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT670597	hsa-miR-612	HITS-CLIP	23824327
MIRT670596	hsa-miR-6860	HITS-CLIP	23824327
MIRT670595	hsa-miR-6132	HITS-CLIP	23824327
MIRT670594	hsa-miR-6836-5p	HITS-CLIP	23824327
MIRT670593	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT670592	hsa-miR-4284	HITS-CLIP	23824327
MIRT030531	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT670591	hsa-miR-4505	HITS-CLIP	23824327
MIRT670590	hsa-miR-5787	HITS-CLIP	23824327
MIRT670588	hsa-miR-3945	HITS-CLIP	23824327
MIRT670589	hsa-miR-4253	HITS-CLIP	23824327
MIRT670587	hsa-miR-6862-5p	HITS-CLIP	23824327
MIRT670586	hsa-miR-4492	HITS-CLIP	23824327
MIRT670585	hsa-miR-4498	HITS-CLIP	23824327
MIRT670584	hsa-miR-5001-5p	HITS-CLIP	23824327
MIRT670583	hsa-miR-762	HITS-CLIP	23824327
MIRT670582	hsa-miR-7977	HITS-CLIP	23824327
MIRT670581	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT670580	hsa-miR-3122	HITS-CLIP	23824327
MIRT670579	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT670578	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT670577	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT694754	hsa-miR-3929	HITS-CLIP	23313552
MIRT694753	hsa-miR-4419b	HITS-CLIP	23313552
MIRT694752	hsa-miR-4478	HITS-CLIP	23313552
MIRT670602	hsa-miR-4446-3p	HITS-CLIP	23313552
MIRT670601	hsa-miR-383-3p	HITS-CLIP	23313552
MIRT694751	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT670600	hsa-miR-1285-3p	HITS-CLIP	23313552
MIRT670599	hsa-miR-3187-5p	HITS-CLIP	23313552
MIRT670598	hsa-miR-5189-5p	HITS-CLIP	23313552
MIRT670597	hsa-miR-612	HITS-CLIP	23313552
MIRT670596	hsa-miR-6860	HITS-CLIP	23313552
MIRT694750	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694749	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT694748	hsa-miR-7854-3p	HITS-CLIP	23313552
MIRT694747	hsa-miR-6134	HITS-CLIP	23313552
MIRT670595	hsa-miR-6132	HITS-CLIP	23313552
MIRT670594	hsa-miR-6836-5p	HITS-CLIP	23313552
MIRT694746	hsa-miR-1909-3p	HITS-CLIP	23313552
MIRT694745	hsa-miR-6722-3p	HITS-CLIP	23313552
MIRT694744	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT670593	hsa-miR-3622b-5p	HITS-CLIP	23313552
MIRT670592	hsa-miR-4284	HITS-CLIP	23313552
MIRT030531	hsa-miR-24-3p	HITS-CLIP	23313552
MIRT670591	hsa-miR-4505	HITS-CLIP	23313552
MIRT670590	hsa-miR-5787	HITS-CLIP	23313552
MIRT694743	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT694742	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT694741	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT694740	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT694739	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT694738	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT670588	hsa-miR-3945	HITS-CLIP	23313552
MIRT670589	hsa-miR-4253	HITS-CLIP	23313552
MIRT670587	hsa-miR-6862-5p	HITS-CLIP	23313552
MIRT670586	hsa-miR-4492	HITS-CLIP	23313552
MIRT670585	hsa-miR-4498	HITS-CLIP	23313552
MIRT670584	hsa-miR-5001-5p	HITS-CLIP	23313552
MIRT670583	hsa-miR-762	HITS-CLIP	23313552
MIRT694737	hsa-miR-363-5p	HITS-CLIP	23313552
MIRT694736	hsa-miR-6745	HITS-CLIP	23313552
MIRT694735	hsa-miR-6756-5p	HITS-CLIP	23313552
MIRT694734	hsa-miR-6766-5p	HITS-CLIP	23313552
MIRT694733	hsa-miR-1293	HITS-CLIP	23313552
MIRT694732	hsa-miR-4483	HITS-CLIP	23313552
MIRT694731	hsa-miR-3165	HITS-CLIP	23313552
MIRT694730	hsa-miR-6769a-5p	HITS-CLIP	23313552
MIRT694729	hsa-miR-6769b-5p	HITS-CLIP	23313552
MIRT694728	hsa-miR-6748-5p	HITS-CLIP	23313552
MIRT670582	hsa-miR-7977	HITS-CLIP	23313552
MIRT694727	hsa-miR-6511b-5p	HITS-CLIP	23313552
MIRT694726	hsa-miR-6811-5p	HITS-CLIP	23313552
MIRT694725	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT694724	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT694723	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT694722	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT694721	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT694720	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT694719	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT694718	hsa-miR-3689c	HITS-CLIP	23313552
MIRT694717	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT694716	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT670581	hsa-miR-450a-1-3p	HITS-CLIP	23313552
MIRT670580	hsa-miR-3122	HITS-CLIP	23313552
MIRT670579	hsa-miR-3913-5p	HITS-CLIP	23313552
MIRT670578	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT670577	hsa-miR-6513-5p	HITS-CLIP	23313552
MIRT694715	hsa-miR-665	HITS-CLIP	23313552
MIRT670602	hsa-miR-4446-3p	HITS-CLIP	23824327
MIRT670601	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT670600	hsa-miR-1285-3p	HITS-CLIP	23824327
MIRT670599	hsa-miR-3187-5p	HITS-CLIP	23824327
MIRT670598	hsa-miR-5189-5p	HITS-CLIP	23824327
MIRT670597	hsa-miR-612	HITS-CLIP	23824327
MIRT670596	hsa-miR-6860	HITS-CLIP	23824327
MIRT670595	hsa-miR-6132	HITS-CLIP	23824327
MIRT670594	hsa-miR-6836-5p	HITS-CLIP	23824327
MIRT670593	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT670592	hsa-miR-4284	HITS-CLIP	23824327
MIRT030531	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT670591	hsa-miR-4505	HITS-CLIP	23824327
MIRT670590	hsa-miR-5787	HITS-CLIP	23824327
MIRT670588	hsa-miR-3945	HITS-CLIP	23824327
MIRT670589	hsa-miR-4253	HITS-CLIP	23824327
MIRT670587	hsa-miR-6862-5p	HITS-CLIP	23824327
MIRT670586	hsa-miR-4492	HITS-CLIP	23824327
MIRT670585	hsa-miR-4498	HITS-CLIP	23824327
MIRT670584	hsa-miR-5001-5p	HITS-CLIP	23824327
MIRT670583	hsa-miR-762	HITS-CLIP	23824327
MIRT670582	hsa-miR-7977	HITS-CLIP	23824327
MIRT670581	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT670580	hsa-miR-3122	HITS-CLIP	23824327
MIRT670579	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT670578	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT670577	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT1110838	hsa-miR-105	CLIP-seq
MIRT1110839	hsa-miR-1268	CLIP-seq
MIRT1110840	hsa-miR-1268b	CLIP-seq
MIRT1110841	hsa-miR-1285	CLIP-seq
MIRT1110842	hsa-miR-147	CLIP-seq
MIRT1110843	hsa-miR-1827	CLIP-seq
MIRT1110844	hsa-miR-1908	CLIP-seq
MIRT1110845	hsa-miR-1909	CLIP-seq
MIRT1110846	hsa-miR-1915	CLIP-seq
MIRT1110847	hsa-miR-193a-3p	CLIP-seq
MIRT1110848	hsa-miR-193b	CLIP-seq
MIRT1110849	hsa-miR-2114	CLIP-seq
MIRT1110850	hsa-miR-24	CLIP-seq
MIRT1110851	hsa-miR-296-5p	CLIP-seq
MIRT1110852	hsa-miR-298	CLIP-seq
MIRT1110853	hsa-miR-3136-3p	CLIP-seq
MIRT1110854	hsa-miR-3178	CLIP-seq
MIRT1110855	hsa-miR-3199	CLIP-seq
MIRT1110856	hsa-miR-323-5p	CLIP-seq
MIRT1110857	hsa-miR-361-3p	CLIP-seq
MIRT1110858	hsa-miR-3650	CLIP-seq
MIRT1110859	hsa-miR-3665	CLIP-seq
MIRT1110860	hsa-miR-3675-3p	CLIP-seq
MIRT1110861	hsa-miR-3689d	CLIP-seq
MIRT1110862	hsa-miR-3911	CLIP-seq
MIRT1110863	hsa-miR-4433	CLIP-seq
MIRT1110864	hsa-miR-4436b-3p	CLIP-seq
MIRT1110865	hsa-miR-4459	CLIP-seq
MIRT1110866	hsa-miR-4486	CLIP-seq
MIRT1110867	hsa-miR-4515	CLIP-seq
MIRT1110868	hsa-miR-4649-3p	CLIP-seq
MIRT1110869	hsa-miR-4683	CLIP-seq
MIRT1110870	hsa-miR-4684-5p	CLIP-seq
MIRT1110871	hsa-miR-4685-5p	CLIP-seq
MIRT1110872	hsa-miR-4723-5p	CLIP-seq
MIRT1110873	hsa-miR-4736	CLIP-seq
MIRT1110874	hsa-miR-4768-3p	CLIP-seq
MIRT1110875	hsa-miR-4786-5p	CLIP-seq
MIRT1110876	hsa-miR-4793-5p	CLIP-seq
MIRT1110877	hsa-miR-4794	CLIP-seq
MIRT1110878	hsa-miR-541	CLIP-seq
MIRT1110879	hsa-miR-548c-3p	CLIP-seq
MIRT1110880	hsa-miR-566	CLIP-seq
MIRT1110881	hsa-miR-585	CLIP-seq
MIRT1110882	hsa-miR-644	CLIP-seq
MIRT1110883	hsa-miR-654-5p	CLIP-seq
MIRT1110884	hsa-miR-663	CLIP-seq
MIRT1110885	hsa-miR-876-3p	CLIP-seq
MIRT1110886	hsa-miR-890	CLIP-seq
MIRT2030974	hsa-miR-1273f	CLIP-seq
MIRT1110844	hsa-miR-1908	CLIP-seq
MIRT2030975	hsa-miR-3675-5p	CLIP-seq
MIRT2030976	hsa-miR-3687	CLIP-seq
MIRT1110863	hsa-miR-4433	CLIP-seq
MIRT2030977	hsa-miR-4442	CLIP-seq
MIRT1110865	hsa-miR-4459	CLIP-seq
MIRT1110869	hsa-miR-4683	CLIP-seq
MIRT2030978	hsa-miR-4731-5p	CLIP-seq
MIRT1110874	hsa-miR-4768-3p	CLIP-seq
MIRT1110875	hsa-miR-4786-5p	CLIP-seq
MIRT1110876	hsa-miR-4793-5p	CLIP-seq
MIRT1110877	hsa-miR-4794	CLIP-seq
MIRT1110884	hsa-miR-663	CLIP-seq
MIRT2261652	hsa-miR-1273	CLIP-seq
MIRT2030974	hsa-miR-1273f	CLIP-seq
MIRT1110841	hsa-miR-1285	CLIP-seq
MIRT1110843	hsa-miR-1827	CLIP-seq
MIRT2261653	hsa-miR-1913	CLIP-seq
MIRT1110849	hsa-miR-2114	CLIP-seq
MIRT1110850	hsa-miR-24	CLIP-seq
MIRT1110852	hsa-miR-298	CLIP-seq
MIRT1110854	hsa-miR-3178	CLIP-seq
MIRT1110856	hsa-miR-323-5p	CLIP-seq
MIRT2261654	hsa-miR-324-3p	CLIP-seq
MIRT2030975	hsa-miR-3675-5p	CLIP-seq
MIRT2261655	hsa-miR-4252	CLIP-seq
MIRT2261656	hsa-miR-4313	CLIP-seq
MIRT1110863	hsa-miR-4433	CLIP-seq
MIRT1110865	hsa-miR-4459	CLIP-seq
MIRT1110866	hsa-miR-4486	CLIP-seq
MIRT1110868	hsa-miR-4649-3p	CLIP-seq
MIRT2261657	hsa-miR-4649-5p	CLIP-seq
MIRT1110869	hsa-miR-4683	CLIP-seq
MIRT1110874	hsa-miR-4768-3p	CLIP-seq
MIRT1110875	hsa-miR-4786-5p	CLIP-seq
MIRT2261658	hsa-miR-4793-3p	CLIP-seq
MIRT1110876	hsa-miR-4793-5p	CLIP-seq
MIRT2261659	hsa-miR-508-5p	CLIP-seq
MIRT1110878	hsa-miR-541	CLIP-seq
MIRT1110880	hsa-miR-566	CLIP-seq
MIRT1110883	hsa-miR-654-5p	CLIP-seq
MIRT2261660	hsa-miR-661	CLIP-seq
MIRT2261661	hsa-miR-766	CLIP-seq
MIRT1110885	hsa-miR-876-3p	CLIP-seq
MIRT1110886	hsa-miR-890	CLIP-seq
MIRT2261652	hsa-miR-1273	CLIP-seq
MIRT2261653	hsa-miR-1913	CLIP-seq
MIRT2261654	hsa-miR-324-3p	CLIP-seq
MIRT2030975	hsa-miR-3675-5p	CLIP-seq
MIRT1110861	hsa-miR-3689d	CLIP-seq
MIRT2261655	hsa-miR-4252	CLIP-seq
MIRT2261656	hsa-miR-4313	CLIP-seq
MIRT1110866	hsa-miR-4486	CLIP-seq
MIRT2261657	hsa-miR-4649-5p	CLIP-seq
MIRT2261658	hsa-miR-4793-3p	CLIP-seq
MIRT2261659	hsa-miR-508-5p	CLIP-seq
MIRT2261660	hsa-miR-661	CLIP-seq
MIRT2261661	hsa-miR-766	CLIP-seq
MIRT1110839	hsa-miR-1268	CLIP-seq
MIRT1110840	hsa-miR-1268b	CLIP-seq
MIRT1110860	hsa-miR-3675-3p	CLIP-seq
MIRT1110863	hsa-miR-4433	CLIP-seq
MIRT1110865	hsa-miR-4459	CLIP-seq
MIRT1110866	hsa-miR-4486	CLIP-seq
MIRT1110869	hsa-miR-4683	CLIP-seq
MIRT1110870	hsa-miR-4684-5p	CLIP-seq
MIRT1110874	hsa-miR-4768-3p	CLIP-seq
MIRT1110879	hsa-miR-548c-3p	CLIP-seq
MIRT1110881	hsa-miR-585	CLIP-seq
MIRT2261652	hsa-miR-1273	CLIP-seq
MIRT2561668	hsa-miR-3658	CLIP-seq
MIRT1110860	hsa-miR-3675-3p	CLIP-seq
MIRT2261655	hsa-miR-4252	CLIP-seq
MIRT2561669	hsa-miR-4432	CLIP-seq
MIRT1110863	hsa-miR-4433	CLIP-seq
MIRT1110865	hsa-miR-4459	CLIP-seq
MIRT1110866	hsa-miR-4486	CLIP-seq
MIRT2561670	hsa-miR-451b	CLIP-seq
MIRT2261657	hsa-miR-4649-5p	CLIP-seq
MIRT1110869	hsa-miR-4683	CLIP-seq
MIRT1110870	hsa-miR-4684-5p	CLIP-seq
MIRT2561671	hsa-miR-4696	CLIP-seq
MIRT1110874	hsa-miR-4768-3p	CLIP-seq
MIRT1110875	hsa-miR-4786-5p	CLIP-seq
MIRT2261658	hsa-miR-4793-3p	CLIP-seq
MIRT1110876	hsa-miR-4793-5p	CLIP-seq
MIRT1110877	hsa-miR-4794	CLIP-seq
MIRT2261659	hsa-miR-508-5p	CLIP-seq
MIRT1110879	hsa-miR-548c-3p	CLIP-seq
MIRT2261660	hsa-miR-661	CLIP-seq
MIRT2261661	hsa-miR-766	CLIP-seq
MIRT1110839	hsa-miR-1268	CLIP-seq
MIRT1110840	hsa-miR-1268b	CLIP-seq
MIRT2261652	hsa-miR-1273	CLIP-seq
MIRT1110860	hsa-miR-3675-3p	CLIP-seq
MIRT2261655	hsa-miR-4252	CLIP-seq
MIRT2561669	hsa-miR-4432	CLIP-seq
MIRT1110863	hsa-miR-4433	CLIP-seq
MIRT1110865	hsa-miR-4459	CLIP-seq
MIRT1110866	hsa-miR-4486	CLIP-seq
MIRT2561670	hsa-miR-451b	CLIP-seq
MIRT2261657	hsa-miR-4649-5p	CLIP-seq
MIRT1110869	hsa-miR-4683	CLIP-seq
MIRT1110870	hsa-miR-4684-5p	CLIP-seq
MIRT2561671	hsa-miR-4696	CLIP-seq
MIRT1110874	hsa-miR-4768-3p	CLIP-seq
MIRT1110875	hsa-miR-4786-5p	CLIP-seq
MIRT2261658	hsa-miR-4793-3p	CLIP-seq
MIRT1110876	hsa-miR-4793-5p	CLIP-seq
MIRT1110877	hsa-miR-4794	CLIP-seq
MIRT2261659	hsa-miR-508-5p	CLIP-seq
MIRT1110879	hsa-miR-548c-3p	CLIP-seq
MIRT1110881	hsa-miR-585	CLIP-seq
MIRT2261660	hsa-miR-661	CLIP-seq
MIRT2261661	hsa-miR-766	CLIP-seq

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000137	Component	Golgi cis cisterna	ISS
GO:0005096	Function	GTPase activator activity	IBA	21873635
GO:0005096	Function	GTPase activator activity	ISS
GO:0005198	Function	Structural molecule activity	TAS	7542763
GO:0005515	Function	Protein binding	IPI	7542763
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	7542763
GO:0005856	Component	Cytoskeleton	TAS	7542763
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0006887	Process	Exocytosis	IEA
GO:0006893	Process	Golgi to plasma membrane transport	ISS
GO:0007409	Process	Axonogenesis	ISS
GO:0008593	Process	Regulation of Notch signaling pathway	IBA	21873635
GO:0019901	Function	Protein kinase binding	IDA	7542763
GO:0030424	Component	Axon	ISS
GO:0030864	Component	Cortical actin cytoskeleton	IBA	21873635
GO:0030864	Component	Cortical actin cytoskeleton	IDA	7542763
GO:0030866	Process	Cortical actin cytoskeleton organization	IBA	21873635
GO:0030866	Process	Cortical actin cytoskeleton organization	IDA	7542763
GO:0031901	Component	Early endosome membrane	ISS
GO:0032588	Component	Trans-Golgi network membrane	ISS
GO:0032878	Process	Regulation of establishment or maintenance of cell polarity	IBA	21873635
GO:0043547	Process	Positive regulation of GTPase activity	IEA
GO:0045159	Function	Myosin II binding	IBA	21873635
GO:0050708	Process	Regulation of protein secretion	IBA	21873635
GO:0051294	Process	Establishment of spindle orientation	IBA	21873635
GO:0065003	Process	Protein-containing complex assembly	IDA	7542763

MIM	HGNC	e!Ensembl
600966	6628	ENSG00000131899

Protein

UniProt ID

Q15334

Protein name

Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)

Protein function

Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial

PDB

8R3Y

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08366	LLGL	279 → 380	LLGL2	Family
PF00400	WD40	422 → 461	WD domain, G-beta repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease. {ECO:0000269|P

Sequence

MMKFRFRRQGADPQREKLKQELFAFNKTVEHGFPNQPSALAFDPELRIMAIGTRSGAVKI
YGAPGVEFTGLHRDAATVTQMHFLTGQGRLLSLLDDSSLHLWEIVHHNGCAHLEEALSFQ
LPSRPGFDGASAPLSLTRVTVVLLVAASDIAALGTEGSSVFFLDVTTLTLLEGQTLAPGE
VLRSVPDDYRCGKALGPVESLQGHLRDPTKILIGYSRGLLVIWNQASQCVDHIFLGNQQL
ESLCWGRDSSTVVSSHSDGSYAVWSVDAGSFPTLQPTVATTPYGPFPCKAINKILWRNCE
SGGHFIIFSGGMPRASYGDRHCVSVLRAETLVTLDFTSRIIDFFTVHSTRPEDEFDDPQA
LAVLLEEELVVLDLQTPGWPAVPAPYLAPLHSSAITCSAHVASVPAKLWARIVSAGEQQS
PQPVSSALSWPITGGRNLAQEPSQRGLLLTGHEDGTVRFWDASGVALRPLYKLSTAGLFQ
TDCEHADSLAQAAEDDWPPFRKVGCFDPYSDDPRLGVQKVALCKYTAQMVVAGTAGQVLV
LELSDVPVEQAVSVAIIDLLQDREGFTWKGHERLSPRTGPLPWPAGFQPRVLVQCLPPAA
VTAVTLHTEWSLVAFGTSHGFGLFDYQRKSPVLARCTLHPNDSLAMEGPLSRVKSLKKSL
RQSFRRIRKSRVSGKKRAANASSKLQEANAQLAEQACPHDVEMTPVQRRIEPRSADDSLS
GVVRCLYFADTFLRDGAHHGPTMWAGTNSGSVFAYALEVPAAAVGGEKRPEQAVEAVLGK
EVQLMHRAPVVAIAVLDGRGRPLPEPYEASRDLAQAPDMQGGHAVLIASEEQFKVFTLPK
VSAKTKFKLTAHEGCRVRKVALATFASVACEDYAETCLACLTNLGDVHVFSVPGLRPQVH
YSCIRKEDISGIASCVFTRHGQGFYLISPSEFERFSLSARNITEPLCSLDINWPRDATQA
SYRIRESPKLSQANGTPSILLAPQSLDGSPDPAHSMGPDTPEPPEAALSPMSIDSATSAD
TTLDTTGDVTVEDVKDFLGSSEESEKNLRNLAEDEAHACAILIK

Sequence length

1064

Interactions

View interactions

	KEGG
	Hippo signaling pathway Tight junction Human papillomavirus infection

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)	16298037
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	16298037
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465 View all (942 more)	16298037

Show/Hide Text Mining Associations (7)

Disease Name	Relationship Type	References
Associations from Text Mining
Carcinoma Pancreatic Ductal	Associate	32615164
Carcinoma Squamous Cell	Inhibit	26662669
Frontotemporal Dementia	Associate	37003407
Lung Neoplasms	Inhibit	26662669
Neoplasms	Associate	23110097, 26662669, 26919101, 32615164
Potocki Lupski syndrome	Associate	28413209
Primary Ovarian Insufficiency	Associate	34718612

LLGL1 (LLGL scribble cell polarity complex component 1)