Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3777
Gene name Gene Name - the full gene name approved by the HGNC.	Potassium two pore domain channel subfamily K member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	KCNK3
Synonyms (NCBI Gene) Gene synonyms aliases	K2p3.1, OAT1, PPH4, TASK, TASK-1, TASK1, TBAK1
Disease Acronyms (UniProt) Disease acronyms from UniProt database	PPH4
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2p23.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular

Show/Hide all(7)

SNP ID	Visualize variation	Clinical significance	Consequence
rs398123039	G>A	Pathogenic	Coding sequence variant, missense variant
rs398123040	G>A	Pathogenic	5 prime UTR variant, coding sequence variant, missense variant
rs398123041	G>C	Pathogenic	Coding sequence variant, missense variant
rs398123042	G>A,C	Likely-pathogenic, pathogenic	Coding sequence variant, missense variant
rs398123043	A>G	Pathogenic	Coding sequence variant, missense variant
rs1085307438	C>A	Pathogenic	Genic upstream transcript variant, missense variant, coding sequence variant
rs1553387422	T>C	Likely-pathogenic	Coding sequence variant, missense variant

Show/Hide all(248)

miRTarBase ID	miRNA	Experiments	Reference
MIRT623516	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT623515	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT623514	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT623513	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT623516	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT623515	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT623514	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT623513	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT623512	hsa-miR-3199	HITS-CLIP	23824327
MIRT623511	hsa-miR-8052	HITS-CLIP	23824327
MIRT623510	hsa-miR-365a-5p	HITS-CLIP	23824327
MIRT623509	hsa-miR-365b-5p	HITS-CLIP	23824327
MIRT493435	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT493434	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT493433	hsa-miR-3621	PAR-CLIP	23592263
MIRT493432	hsa-miR-3656	PAR-CLIP	23592263
MIRT493431	hsa-miR-3180	PAR-CLIP	23592263
MIRT493430	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT493429	hsa-miR-3196	PAR-CLIP	23592263
MIRT493428	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT493427	hsa-miR-4417	PAR-CLIP	23592263
MIRT493426	hsa-miR-4265	PAR-CLIP	23592263
MIRT493424	hsa-miR-4296	PAR-CLIP	23592263
MIRT493425	hsa-miR-4322	PAR-CLIP	23592263
MIRT459615	hsa-miR-6732-5p	PAR-CLIP	23592263
MIRT459614	hsa-miR-4707-5p	PAR-CLIP	23592263
MIRT459613	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT459612	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT459611	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT459610	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT459609	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT459608	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT459606	hsa-miR-8085	PAR-CLIP	23592263
MIRT459607	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT459605	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT459603	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT459604	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT459602	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT459601	hsa-miR-6752-5p	PAR-CLIP	23592263
MIRT459600	hsa-miR-6842-5p	PAR-CLIP	23592263
MIRT459599	hsa-miR-7110-5p	PAR-CLIP	23592263
MIRT459598	hsa-miR-4651	PAR-CLIP	23592263
MIRT459597	hsa-miR-608	PAR-CLIP	23592263
MIRT459596	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT459595	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT459594	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT459593	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT459592	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT459591	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT459590	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT493430	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT493430	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT493430	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT493431	hsa-miR-3180	PAR-CLIP	26701625
MIRT493431	hsa-miR-3180	PAR-CLIP	26701625
MIRT493431	hsa-miR-3180	PAR-CLIP	26701625
MIRT493435	hsa-miR-3184-5p	PAR-CLIP	26701625
MIRT493435	hsa-miR-3184-5p	PAR-CLIP	26701625
MIRT493435	hsa-miR-3184-5p	PAR-CLIP	26701625
MIRT493429	hsa-miR-3196	PAR-CLIP	26701625
MIRT493429	hsa-miR-3196	PAR-CLIP	26701625
MIRT493429	hsa-miR-3196	PAR-CLIP	26701625
MIRT493433	hsa-miR-3621	PAR-CLIP	26701625
MIRT493433	hsa-miR-3621	PAR-CLIP	26701625
MIRT493433	hsa-miR-3621	PAR-CLIP	26701625
MIRT493432	hsa-miR-3656	PAR-CLIP	26701625
MIRT493432	hsa-miR-3656	PAR-CLIP	26701625
MIRT493432	hsa-miR-3656	PAR-CLIP	26701625
MIRT493434	hsa-miR-423-5p	PAR-CLIP	26701625
MIRT493434	hsa-miR-423-5p	PAR-CLIP	26701625
MIRT493434	hsa-miR-423-5p	PAR-CLIP	26701625
MIRT493426	hsa-miR-4265	PAR-CLIP	26701625
MIRT493426	hsa-miR-4265	PAR-CLIP	26701625
MIRT493426	hsa-miR-4265	PAR-CLIP	26701625
MIRT493424	hsa-miR-4296	PAR-CLIP	26701625
MIRT493424	hsa-miR-4296	PAR-CLIP	26701625
MIRT493424	hsa-miR-4296	PAR-CLIP	26701625
MIRT493425	hsa-miR-4322	PAR-CLIP	26701625
MIRT493425	hsa-miR-4322	PAR-CLIP	26701625
MIRT493425	hsa-miR-4322	PAR-CLIP	26701625
MIRT493427	hsa-miR-4417	PAR-CLIP	26701625
MIRT493427	hsa-miR-4417	PAR-CLIP	26701625
MIRT493427	hsa-miR-4417	PAR-CLIP	26701625
MIRT493428	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT493428	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT493428	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT623516	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT623515	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT623514	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT623513	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT623516	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT623515	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT623514	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT623513	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT623512	hsa-miR-3199	HITS-CLIP	23824327
MIRT623511	hsa-miR-8052	HITS-CLIP	23824327
MIRT623510	hsa-miR-365a-5p	HITS-CLIP	23824327
MIRT623509	hsa-miR-365b-5p	HITS-CLIP	23824327
MIRT493435	hsa-miR-3184-5p	PAR-CLIP	23592263
MIRT493434	hsa-miR-423-5p	PAR-CLIP	23592263
MIRT493433	hsa-miR-3621	PAR-CLIP	23592263
MIRT493432	hsa-miR-3656	PAR-CLIP	23592263
MIRT493431	hsa-miR-3180	PAR-CLIP	23592263
MIRT493430	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT493429	hsa-miR-3196	PAR-CLIP	23592263
MIRT493428	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT493427	hsa-miR-4417	PAR-CLIP	23592263
MIRT493426	hsa-miR-4265	PAR-CLIP	23592263
MIRT493424	hsa-miR-4296	PAR-CLIP	23592263
MIRT493425	hsa-miR-4322	PAR-CLIP	23592263
MIRT459615	hsa-miR-6732-5p	PAR-CLIP	23592263
MIRT459614	hsa-miR-4707-5p	PAR-CLIP	23592263
MIRT459613	hsa-miR-1909-3p	PAR-CLIP	23592263
MIRT459612	hsa-miR-6722-3p	PAR-CLIP	23592263
MIRT459611	hsa-miR-1207-5p	PAR-CLIP	23592263
MIRT459610	hsa-miR-4763-3p	PAR-CLIP	23592263
MIRT459609	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT459608	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT459606	hsa-miR-8085	PAR-CLIP	23592263
MIRT459607	hsa-miR-149-3p	PAR-CLIP	23592263
MIRT459605	hsa-miR-4728-5p	PAR-CLIP	23592263
MIRT459603	hsa-miR-6785-5p	PAR-CLIP	23592263
MIRT459604	hsa-miR-6883-5p	PAR-CLIP	23592263
MIRT459602	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT459601	hsa-miR-6752-5p	PAR-CLIP	23592263
MIRT459600	hsa-miR-6842-5p	PAR-CLIP	23592263
MIRT459599	hsa-miR-7110-5p	PAR-CLIP	23592263
MIRT459598	hsa-miR-4651	PAR-CLIP	23592263
MIRT459597	hsa-miR-608	PAR-CLIP	23592263
MIRT459596	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT459595	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT459594	hsa-miR-1233-5p	PAR-CLIP	23592263
MIRT459593	hsa-miR-6778-5p	PAR-CLIP	23592263
MIRT459592	hsa-miR-30c-1-3p	PAR-CLIP	23592263
MIRT459591	hsa-miR-30c-2-3p	PAR-CLIP	23592263
MIRT459590	hsa-miR-6788-5p	PAR-CLIP	23592263
MIRT755484	hsa-miR-34a-3p	Western blotting, qRT-PCR	35301863
MIRT1081840	hsa-miR-214	CLIP-seq
MIRT1081841	hsa-miR-3619-5p	CLIP-seq
MIRT1081842	hsa-miR-371b-3p	CLIP-seq
MIRT1081843	hsa-miR-4290	CLIP-seq
MIRT1081844	hsa-miR-4291	CLIP-seq
MIRT1081845	hsa-miR-4454	CLIP-seq
MIRT1081846	hsa-miR-4519	CLIP-seq
MIRT1081847	hsa-miR-4763-5p	CLIP-seq
MIRT1081848	hsa-miR-485-5p	CLIP-seq
MIRT1081849	hsa-miR-488	CLIP-seq
MIRT1081850	hsa-miR-761	CLIP-seq
MIRT1081851	hsa-miR-922	CLIP-seq
MIRT1550412	hsa-miR-1827	CLIP-seq
MIRT1550413	hsa-miR-1913	CLIP-seq
MIRT1550414	hsa-miR-324-3p	CLIP-seq
MIRT1550415	hsa-miR-4313	CLIP-seq
MIRT2020302	hsa-miR-1286	CLIP-seq
MIRT2020303	hsa-miR-1915	CLIP-seq
MIRT2020304	hsa-miR-202	CLIP-seq
MIRT2020305	hsa-miR-2682	CLIP-seq
MIRT2020306	hsa-miR-3127-5p	CLIP-seq
MIRT2020307	hsa-miR-3135b	CLIP-seq
MIRT2020308	hsa-miR-34a	CLIP-seq
MIRT2020309	hsa-miR-34c-5p	CLIP-seq
MIRT2020310	hsa-miR-3652	CLIP-seq
MIRT2020311	hsa-miR-3714	CLIP-seq
MIRT2020312	hsa-miR-3918	CLIP-seq
MIRT2020313	hsa-miR-4257	CLIP-seq
MIRT2020314	hsa-miR-4284	CLIP-seq
MIRT2020315	hsa-miR-4430	CLIP-seq
MIRT2020316	hsa-miR-4436a	CLIP-seq
MIRT2020317	hsa-miR-4437	CLIP-seq
MIRT2020318	hsa-miR-449a	CLIP-seq
MIRT2020319	hsa-miR-449b	CLIP-seq
MIRT2020320	hsa-miR-449c	CLIP-seq
MIRT2020321	hsa-miR-4690-5p	CLIP-seq
MIRT2020322	hsa-miR-4726-3p	CLIP-seq
MIRT2020323	hsa-miR-4747-5p	CLIP-seq
MIRT2020324	hsa-miR-769-5p	CLIP-seq
MIRT2252093	hsa-miR-129-5p	CLIP-seq
MIRT2252094	hsa-miR-1302	CLIP-seq
MIRT2252095	hsa-miR-1321	CLIP-seq
MIRT2252096	hsa-miR-1343	CLIP-seq
MIRT2252097	hsa-miR-146b-3p	CLIP-seq
MIRT1550412	hsa-miR-1827	CLIP-seq
MIRT2020305	hsa-miR-2682	CLIP-seq
MIRT2252098	hsa-miR-3122	CLIP-seq
MIRT2020306	hsa-miR-3127-5p	CLIP-seq
MIRT2020307	hsa-miR-3135b	CLIP-seq
MIRT2252099	hsa-miR-3173-5p	CLIP-seq
MIRT2252100	hsa-miR-339-5p	CLIP-seq
MIRT2020308	hsa-miR-34a	CLIP-seq
MIRT2252101	hsa-miR-34c-3p	CLIP-seq
MIRT2020309	hsa-miR-34c-5p	CLIP-seq
MIRT2020310	hsa-miR-3652	CLIP-seq
MIRT2020311	hsa-miR-3714	CLIP-seq
MIRT2252102	hsa-miR-377	CLIP-seq
MIRT2252103	hsa-miR-378g	CLIP-seq
MIRT2252104	hsa-miR-3913-5p	CLIP-seq
MIRT2020312	hsa-miR-3918	CLIP-seq
MIRT2252105	hsa-miR-4298	CLIP-seq
MIRT2020315	hsa-miR-4430	CLIP-seq
MIRT2020316	hsa-miR-4436a	CLIP-seq
MIRT2020317	hsa-miR-4437	CLIP-seq
MIRT2020318	hsa-miR-449a	CLIP-seq
MIRT2020319	hsa-miR-449b	CLIP-seq
MIRT2020320	hsa-miR-449c	CLIP-seq
MIRT2252106	hsa-miR-4661-5p	CLIP-seq
MIRT2252107	hsa-miR-4674	CLIP-seq
MIRT2252108	hsa-miR-4691-5p	CLIP-seq
MIRT2252109	hsa-miR-4700-3p	CLIP-seq
MIRT2252110	hsa-miR-4739	CLIP-seq
MIRT2020323	hsa-miR-4747-5p	CLIP-seq
MIRT2252111	hsa-miR-4756-5p	CLIP-seq
MIRT2252112	hsa-miR-615-5p	CLIP-seq
MIRT2252113	hsa-miR-874	CLIP-seq
MIRT2252114	hsa-miR-890	CLIP-seq
MIRT2389657	hsa-miR-1227	CLIP-seq
MIRT2389658	hsa-miR-1228	CLIP-seq
MIRT2020303	hsa-miR-1915	CLIP-seq
MIRT2252103	hsa-miR-378g	CLIP-seq
MIRT2020317	hsa-miR-4437	CLIP-seq
MIRT2252107	hsa-miR-4674	CLIP-seq
MIRT2252108	hsa-miR-4691-5p	CLIP-seq
MIRT2389659	hsa-miR-4715-3p	CLIP-seq
MIRT2020322	hsa-miR-4726-3p	CLIP-seq
MIRT2389660	hsa-miR-4755-3p	CLIP-seq
MIRT2389661	hsa-miR-4775	CLIP-seq
MIRT2389662	hsa-miR-590-3p	CLIP-seq
MIRT2452232	hsa-miR-1285	CLIP-seq
MIRT2452233	hsa-miR-1909	CLIP-seq
MIRT1081840	hsa-miR-214	CLIP-seq
MIRT2452234	hsa-miR-298	CLIP-seq
MIRT2452235	hsa-miR-3187-5p	CLIP-seq
MIRT1081841	hsa-miR-3619-5p	CLIP-seq
MIRT2020311	hsa-miR-3714	CLIP-seq
MIRT2452236	hsa-miR-4688	CLIP-seq
MIRT2452237	hsa-miR-486-3p	CLIP-seq
MIRT2452238	hsa-miR-612	CLIP-seq
MIRT1081850	hsa-miR-761	CLIP-seq
MIRT2555481	hsa-miR-1182	CLIP-seq
MIRT2252097	hsa-miR-146b-3p	CLIP-seq
MIRT2555482	hsa-miR-193a-5p	CLIP-seq
MIRT2020307	hsa-miR-3135b	CLIP-seq
MIRT2555483	hsa-miR-3157-3p	CLIP-seq
MIRT2252099	hsa-miR-3173-5p	CLIP-seq
MIRT2252100	hsa-miR-339-5p	CLIP-seq
MIRT2020310	hsa-miR-3652	CLIP-seq
MIRT2555484	hsa-miR-431	CLIP-seq
MIRT2020315	hsa-miR-4430	CLIP-seq
MIRT2252113	hsa-miR-874	CLIP-seq

Show/Hide all(23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005216	Function	Ion channel activity	IMP	12198146
GO:0005252	Function	Open rectifier potassium channel activity	IEA
GO:0005267	Function	Potassium channel activity	TAS	9312005
GO:0005886	Component	Plasma membrane	IMP	12198146
GO:0005886	Component	Plasma membrane	TAS
GO:0005887	Component	Integral component of plasma membrane	IBA	21873635
GO:0006813	Process	Potassium ion transport	TAS	9312005
GO:0007268	Process	Chemical synaptic transmission	TAS	9312005
GO:0007420	Process	Brain development	IEA
GO:0008022	Function	Protein C-terminus binding	IEA
GO:0022841	Function	Potassium ion leak channel activity	IBA	21873635
GO:0022841	Function	Potassium ion leak channel activity	IDA	9312005
GO:0030322	Process	Stabilization of membrane potential	IBA	21873635
GO:0034220	Process	Ion transmembrane transport	IMP	12198146
GO:0042493	Process	Response to drug	IEA
GO:0044548	Function	S100 protein binding	IPI	12198146
GO:0045202	Component	Synapse	IEA
GO:0051481	Process	Negative regulation of cytosolic calcium ion concentration	IEA
GO:0061337	Process	Cardiac conduction	TAS
GO:0071294	Process	Cellular response to zinc ion	IEA
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0071805	Process	Potassium ion transmembrane transport	IBA	21873635
GO:0090102	Process	Cochlea development	IEA

MIM	HGNC	e!Ensembl
603220	6278	ENSG00000171303

Protein

UniProt ID

O14649

Protein name

Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1) (Two pore K(+) channel KT3.1)

Protein function

K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate

PDB

6RV2 , 6RV3 , 6RV4 , 9G9X

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07885	Ion_trans_2	59 → 134	Ion channel	Family
PF07885	Ion_trans_2	165 → 248	Ion channel	Family

Tissue specificity

TISSUE SPECIFICITY: Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.

Sequence

MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR
CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV

Sequence length

394

Interactions

View interactions

	KEGG		Reactome
	Aldosterone synthesis and secretion Cortisol synthesis and secretion Cushing syndrome		TWIK-releated acid-sensitive K+ channel (TASK) Phase 4 - resting membrane potential

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Hypertension	Hypertensive disease	rs13306026	30487518
Pulmonary arterial hypertension	Familial pulmonary arterial hypertension, Pulmonary arterial hypertension, Idiopathic pulmonary arterial hypertension	rs121909288, rs137852741, rs137852742, rs137852743, rs137852744, rs137852745, rs137852746, rs137852748, rs137852749, rs137852750, rs137852751, rs137852753, rs863223423, rs863223426, rs863223424 View all (116 more)	24951767, 23883380, 28388887
Pulmonary hypertension	Idiopathic pulmonary hypertension, Familial primary pulmonary hypertension, PULMONARY HYPERTENSION, PRIMARY, 4, Pulmonary Hypertension, Primary, 1	rs5030847, rs5030850, rs753751183, rs121912592, rs121912593, rs121912596, rs121918359, rs137852741, rs137852742, rs137852743, rs137852744, rs137852745, rs137852746, rs137852747, rs137852748 View all (349 more)	28388887, 24951767, 23883380

Show/Hide Unknown Diseases (7)

Disease term	Disease name	References	Source
Unknown
Ischemic stroke	Ischemic stroke	29531354	ClinVar
Heritable Pulmonary Arterial Hypertension	heritable pulmonary arterial hypertension		GenCC
Pulmonary Hypertension	pulmonary hypertension, primary, 4		GenCC
Metabolic Syndrome	Metabolic Syndrome		GWAS
Ischemic Stroke	Ischemic Stroke		GWAS
Sarcoidosis	Sarcoidosis		GWAS
Heart Failure	Heart Failure		GWAS

Show/Hide Text Mining Associations (31)

Disease Name	Relationship Type	References
Associations from Text Mining
Atrial Fibrillation	Associate	39637865
Breast Neoplasms	Associate	28252570
Carcinoma Basal Cell	Associate	35011589
Carcinoma Squamous Cell	Associate	35676660
Cardiovascular Diseases	Associate	20665672
Channelopathies	Associate	28388887, 30354297, 33036472
Chemical and Drug Induced Liver Injury	Associate	19034961
Cholestasis Extrahepatic	Associate	19034961
Developmental Disabilities	Associate	36195757
Drug Related Side Effects and Adverse Reactions	Associate	19034961
Familial Primary Pulmonary Hypertension	Associate	23883380, 27453251
Heart Failure	Associate	32159364
Hyperaldosteronism	Associate	22893713, 27296998, 27736895
Hypertension	Associate	22893713, 27296998, 39637865
Hypertension Pulmonary	Associate	26820968
Hypoxia	Inhibit	32045592
Hypoxia Brain	Associate	29257242
Lung Diseases	Associate	32045592
Lymphedema	Associate	28252570
Neoplasms	Associate	24116006, 35011589
Neuromyelitis Optica	Associate	40294019
Non alcoholic Fatty Liver Disease	Associate	37002989
Obesity	Associate	31436597
Pain	Associate	39637865
Pressure Ulcer	Associate	27736895
Pulmonary Arterial Hypertension	Associate	23883380, 25171373, 26699722, 26820968, 27453251, 28388887, 29257242, 30354297, 30365877, 32159364, 35346192
Pulmonary Arterial Hypertension	Inhibit	33036472
Pulmonary Disease Chronic Obstructive	Associate	25171373, 29313708
Skin Neoplasms	Associate	35011589
Sleep Apnea Obstructive	Associate	31436597
Sleep Apnea Syndromes	Associate	36195757, 39637865

KCNK3 (potassium two pore domain channel subfamily K member 3)