Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	3685
Gene name	Integrin subunit alpha V
Gene symbol	ITGAV
Synonyms (NCBI Gene)	CD51MSK8VNRAVTNR
Chromosome	2
Chromosome location	2q32.1
Summary	The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021641	hsa-miR-142-3p	Microarray	17612493
MIRT024872	hsa-miR-215-5p	Microarray	19074876
MIRT026088	hsa-miR-196a-5p	Sequencing	20371350
MIRT026587	hsa-miR-192-5p	Microarray	19074876
MIRT028372	hsa-miR-32-5p	Sequencing	20371350
MIRT021641	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT440423	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT021641	hsa-miR-142-3p	HITS-CLIP	22473208
MIRT440423	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT026587	hsa-miR-192-5p	ImmunofluorescenceLuciferase reporter assayWestern blot	26506238
MIRT734989	hsa-miR-429	qRT-PCR	33079247
MIRT735046	hsa-miR-142-5p	Luciferase reporter assayWestern blottingRNA-seqqRT-PCR	32902370
MIRT1073831	hsa-miR-2053	CLIP-seq
MIRT1073832	hsa-miR-2681	CLIP-seq
MIRT1073833	hsa-miR-331-5p	CLIP-seq
MIRT1073834	hsa-miR-4263	CLIP-seq
MIRT1073835	hsa-miR-4662a-3p	CLIP-seq
MIRT1073836	hsa-miR-4678	CLIP-seq
MIRT1073837	hsa-miR-4775	CLIP-seq
MIRT1073838	hsa-miR-4799-5p	CLIP-seq
MIRT1073839	hsa-miR-569	CLIP-seq
MIRT1073840	hsa-miR-576-5p	CLIP-seq
MIRT1073841	hsa-miR-1183	CLIP-seq
MIRT1073842	hsa-miR-1207-5p	CLIP-seq
MIRT1073843	hsa-miR-1252	CLIP-seq
MIRT1073844	hsa-miR-1273g	CLIP-seq
MIRT1073845	hsa-miR-1284	CLIP-seq
MIRT1073846	hsa-miR-1291	CLIP-seq
MIRT1073847	hsa-miR-129-5p	CLIP-seq
MIRT1073848	hsa-miR-137	CLIP-seq
MIRT1073849	hsa-miR-144	CLIP-seq
MIRT1073850	hsa-miR-146a	CLIP-seq
MIRT1073851	hsa-miR-146b-5p	CLIP-seq
MIRT1073852	hsa-miR-155	CLIP-seq
MIRT1073853	hsa-miR-183	CLIP-seq
MIRT1073854	hsa-miR-188-5p	CLIP-seq
MIRT1073855	hsa-miR-194	CLIP-seq
MIRT1073856	hsa-miR-200b	CLIP-seq
MIRT1073857	hsa-miR-200c	CLIP-seq
MIRT1073858	hsa-miR-203	CLIP-seq
MIRT1073859	hsa-miR-2054	CLIP-seq
MIRT1073860	hsa-miR-2113	CLIP-seq
MIRT1073861	hsa-miR-219-1-3p	CLIP-seq
MIRT1073862	hsa-miR-224	CLIP-seq
MIRT1073863	hsa-miR-25	CLIP-seq
MIRT1073864	hsa-miR-297	CLIP-seq
MIRT1073865	hsa-miR-300	CLIP-seq
MIRT1073866	hsa-miR-3065-5p	CLIP-seq
MIRT1073867	hsa-miR-3133	CLIP-seq
MIRT1073868	hsa-miR-3143	CLIP-seq
MIRT1073869	hsa-miR-3173-3p	CLIP-seq
MIRT1073870	hsa-miR-3174	CLIP-seq
MIRT1073871	hsa-miR-32	CLIP-seq
MIRT1073872	hsa-miR-3200-3p	CLIP-seq
MIRT1073873	hsa-miR-323-3p	CLIP-seq
MIRT1073874	hsa-miR-328	CLIP-seq
MIRT1073875	hsa-miR-340	CLIP-seq
MIRT1073876	hsa-miR-3545-3p	CLIP-seq
MIRT1073877	hsa-miR-3613-3p	CLIP-seq
MIRT1073878	hsa-miR-3614-5p	CLIP-seq
MIRT1073879	hsa-miR-3617	CLIP-seq
MIRT1073880	hsa-miR-3620	CLIP-seq
MIRT1073881	hsa-miR-363	CLIP-seq
MIRT1073882	hsa-miR-365	CLIP-seq
MIRT1073883	hsa-miR-3662	CLIP-seq
MIRT1073884	hsa-miR-367	CLIP-seq
MIRT1073885	hsa-miR-3678-5p	CLIP-seq
MIRT1073886	hsa-miR-371-5p	CLIP-seq
MIRT1073887	hsa-miR-371b-5p	CLIP-seq
MIRT1073888	hsa-miR-374c	CLIP-seq
MIRT1073889	hsa-miR-381	CLIP-seq
MIRT1073890	hsa-miR-3924	CLIP-seq
MIRT1073891	hsa-miR-410	CLIP-seq
MIRT1073892	hsa-miR-4257	CLIP-seq
MIRT1073893	hsa-miR-4269	CLIP-seq
MIRT1073894	hsa-miR-4276	CLIP-seq
MIRT1073895	hsa-miR-4280	CLIP-seq
MIRT1073896	hsa-miR-4311	CLIP-seq
MIRT1073897	hsa-miR-4325	CLIP-seq
MIRT1073898	hsa-miR-4421	CLIP-seq
MIRT1073899	hsa-miR-4423-5p	CLIP-seq
MIRT1073900	hsa-miR-4428	CLIP-seq
MIRT1073901	hsa-miR-4434	CLIP-seq
MIRT1073902	hsa-miR-4477a	CLIP-seq
MIRT1073903	hsa-miR-4511	CLIP-seq
MIRT1073904	hsa-miR-4514	CLIP-seq
MIRT1073905	hsa-miR-4516	CLIP-seq
MIRT1073906	hsa-miR-4517	CLIP-seq
MIRT1073907	hsa-miR-4539	CLIP-seq
MIRT1073908	hsa-miR-4637	CLIP-seq
MIRT1073909	hsa-miR-4666-3p	CLIP-seq
MIRT1073910	hsa-miR-4672	CLIP-seq
MIRT1073911	hsa-miR-4692	CLIP-seq
MIRT1073912	hsa-miR-4720-3p	CLIP-seq
MIRT1073913	hsa-miR-4724-3p	CLIP-seq
MIRT1073914	hsa-miR-4731-3p	CLIP-seq
MIRT1073915	hsa-miR-4736	CLIP-seq
MIRT1073916	hsa-miR-4742-5p	CLIP-seq
MIRT1073917	hsa-miR-4763-3p	CLIP-seq
MIRT1073918	hsa-miR-4780	CLIP-seq
MIRT1073919	hsa-miR-4795-3p	CLIP-seq
MIRT1073920	hsa-miR-4801	CLIP-seq
MIRT1073921	hsa-miR-4804-3p	CLIP-seq
MIRT1073922	hsa-miR-486-5p	CLIP-seq
MIRT1073923	hsa-miR-495	CLIP-seq
MIRT1073924	hsa-miR-496	CLIP-seq
MIRT1073925	hsa-miR-509-3p	CLIP-seq
MIRT1073926	hsa-miR-543	CLIP-seq
MIRT1073927	hsa-miR-548a-5p	CLIP-seq
MIRT1073928	hsa-miR-548ab	CLIP-seq
MIRT1073929	hsa-miR-548ac	CLIP-seq
MIRT1073930	hsa-miR-548ae	CLIP-seq
MIRT1073931	hsa-miR-548aj	CLIP-seq
MIRT1073932	hsa-miR-548ak	CLIP-seq
MIRT1073933	hsa-miR-548am	CLIP-seq
MIRT1073934	hsa-miR-548b-5p	CLIP-seq
MIRT1073935	hsa-miR-548c-5p	CLIP-seq
MIRT1073936	hsa-miR-548d-3p	CLIP-seq
MIRT1073937	hsa-miR-548d-5p	CLIP-seq
MIRT1073938	hsa-miR-548g	CLIP-seq
MIRT1073939	hsa-miR-548h	CLIP-seq
MIRT1073940	hsa-miR-548i	CLIP-seq
MIRT1073941	hsa-miR-548j	CLIP-seq
MIRT1073942	hsa-miR-548k	CLIP-seq
MIRT1073943	hsa-miR-548l	CLIP-seq
MIRT1073944	hsa-miR-548w	CLIP-seq
MIRT1073945	hsa-miR-548x	CLIP-seq
MIRT1073946	hsa-miR-548y	CLIP-seq
MIRT1073947	hsa-miR-548z	CLIP-seq
MIRT1073948	hsa-miR-559	CLIP-seq
MIRT1073949	hsa-miR-561	CLIP-seq
MIRT1073950	hsa-miR-563	CLIP-seq
MIRT1073951	hsa-miR-567	CLIP-seq
MIRT1073839	hsa-miR-569	CLIP-seq
MIRT1073952	hsa-miR-571	CLIP-seq
MIRT1073953	hsa-miR-580	CLIP-seq
MIRT1073954	hsa-miR-589	CLIP-seq
MIRT1073955	hsa-miR-590-3p	CLIP-seq
MIRT1073956	hsa-miR-623	CLIP-seq
MIRT1073957	hsa-miR-640	CLIP-seq
MIRT1073958	hsa-miR-641	CLIP-seq
MIRT1073959	hsa-miR-654-3p	CLIP-seq
MIRT1073960	hsa-miR-655	CLIP-seq
MIRT1073961	hsa-miR-92a	CLIP-seq
MIRT1073962	hsa-miR-92b	CLIP-seq
MIRT1550307	hsa-miR-1224-5p	CLIP-seq
MIRT1550308	hsa-miR-1276	CLIP-seq
MIRT1073896	hsa-miR-4311	CLIP-seq
MIRT1550309	hsa-miR-4751	CLIP-seq
MIRT1073929	hsa-miR-548ac	CLIP-seq
MIRT1073930	hsa-miR-548ae	CLIP-seq
MIRT1073931	hsa-miR-548aj	CLIP-seq
MIRT1073933	hsa-miR-548am	CLIP-seq
MIRT1073936	hsa-miR-548d-3p	CLIP-seq
MIRT1073945	hsa-miR-548x	CLIP-seq
MIRT1073947	hsa-miR-548z	CLIP-seq
MIRT1550310	hsa-miR-583	CLIP-seq
MIRT1073841	hsa-miR-1183	CLIP-seq
MIRT2018233	hsa-miR-1258	CLIP-seq
MIRT2018234	hsa-miR-136	CLIP-seq
MIRT1073848	hsa-miR-137	CLIP-seq
MIRT2018235	hsa-miR-141	CLIP-seq
MIRT2018236	hsa-miR-150	CLIP-seq
MIRT1073855	hsa-miR-194	CLIP-seq
MIRT2018237	hsa-miR-200a	CLIP-seq
MIRT1073865	hsa-miR-300	CLIP-seq
MIRT2018238	hsa-miR-3074-3p	CLIP-seq
MIRT2018239	hsa-miR-3120-5p	CLIP-seq
MIRT2018240	hsa-miR-3129-3p	CLIP-seq
MIRT2018241	hsa-miR-3152-5p	CLIP-seq
MIRT2018242	hsa-miR-3156-5p	CLIP-seq
MIRT1073872	hsa-miR-3200-3p	CLIP-seq
MIRT1073873	hsa-miR-323-3p	CLIP-seq
MIRT1073833	hsa-miR-331-5p	CLIP-seq
MIRT2018243	hsa-miR-361-5p	CLIP-seq
MIRT1073889	hsa-miR-381	CLIP-seq
MIRT2018244	hsa-miR-3941	CLIP-seq
MIRT1073892	hsa-miR-4257	CLIP-seq
MIRT1073834	hsa-miR-4263	CLIP-seq
MIRT1073893	hsa-miR-4269	CLIP-seq
MIRT2018245	hsa-miR-4282	CLIP-seq
MIRT2018246	hsa-miR-4328	CLIP-seq
MIRT1073898	hsa-miR-4421	CLIP-seq
MIRT2018247	hsa-miR-4457	CLIP-seq
MIRT2018248	hsa-miR-4476	CLIP-seq
MIRT1073902	hsa-miR-4477a	CLIP-seq
MIRT2018249	hsa-miR-450b-5p	CLIP-seq
MIRT1073904	hsa-miR-4514	CLIP-seq
MIRT2018250	hsa-miR-4528	CLIP-seq
MIRT2018251	hsa-miR-4643	CLIP-seq
MIRT2018252	hsa-miR-4652-3p	CLIP-seq
MIRT2018253	hsa-miR-466	CLIP-seq
MIRT1073909	hsa-miR-4666-3p	CLIP-seq
MIRT2018254	hsa-miR-4666-5p	CLIP-seq
MIRT1073910	hsa-miR-4672	CLIP-seq
MIRT2018255	hsa-miR-4676-5p	CLIP-seq
MIRT1073836	hsa-miR-4678	CLIP-seq
MIRT1073911	hsa-miR-4692	CLIP-seq
MIRT2018256	hsa-miR-4704-3p	CLIP-seq
MIRT2018257	hsa-miR-4713-5p	CLIP-seq
MIRT1073912	hsa-miR-4720-3p	CLIP-seq
MIRT1073913	hsa-miR-4724-3p	CLIP-seq
MIRT2018258	hsa-miR-4727-5p	CLIP-seq
MIRT2018259	hsa-miR-4735-5p	CLIP-seq
MIRT1073916	hsa-miR-4742-5p	CLIP-seq
MIRT2018260	hsa-miR-4766-5p	CLIP-seq
MIRT2018261	hsa-miR-4769-3p	CLIP-seq
MIRT2018262	hsa-miR-4774-3p	CLIP-seq
MIRT1073837	hsa-miR-4775	CLIP-seq
MIRT2018263	hsa-miR-4778-5p	CLIP-seq
MIRT2018264	hsa-miR-4789-3p	CLIP-seq
MIRT2018265	hsa-miR-4789-5p	CLIP-seq
MIRT1073921	hsa-miR-4804-3p	CLIP-seq
MIRT1073922	hsa-miR-486-5p	CLIP-seq
MIRT2018266	hsa-miR-507	CLIP-seq
MIRT2018267	hsa-miR-513b	CLIP-seq
MIRT2018268	hsa-miR-515-5p	CLIP-seq
MIRT2018269	hsa-miR-520d-5p	CLIP-seq
MIRT2018270	hsa-miR-524-5p	CLIP-seq
MIRT2018271	hsa-miR-532-3p	CLIP-seq
MIRT2018272	hsa-miR-548a-3p	CLIP-seq
MIRT1073927	hsa-miR-548a-5p	CLIP-seq
MIRT1073928	hsa-miR-548ab	CLIP-seq
MIRT1073932	hsa-miR-548ak	CLIP-seq
MIRT1073934	hsa-miR-548b-5p	CLIP-seq
MIRT1073935	hsa-miR-548c-5p	CLIP-seq
MIRT1073937	hsa-miR-548d-5p	CLIP-seq
MIRT2018273	hsa-miR-548e	CLIP-seq
MIRT2018274	hsa-miR-548f	CLIP-seq
MIRT1073938	hsa-miR-548g	CLIP-seq
MIRT1073939	hsa-miR-548h	CLIP-seq
MIRT1073940	hsa-miR-548i	CLIP-seq
MIRT1073941	hsa-miR-548j	CLIP-seq
MIRT1073942	hsa-miR-548k	CLIP-seq
MIRT2018275	hsa-miR-548n	CLIP-seq
MIRT2018276	hsa-miR-548p	CLIP-seq
MIRT1073944	hsa-miR-548w	CLIP-seq
MIRT1073946	hsa-miR-548y	CLIP-seq
MIRT2018277	hsa-miR-557	CLIP-seq
MIRT1073948	hsa-miR-559	CLIP-seq
MIRT2018278	hsa-miR-575	CLIP-seq
MIRT1073840	hsa-miR-576-5p	CLIP-seq
MIRT2018279	hsa-miR-579	CLIP-seq
MIRT1073955	hsa-miR-590-3p	CLIP-seq
MIRT2018280	hsa-miR-607	CLIP-seq
MIRT2018281	hsa-miR-630	CLIP-seq
MIRT2018282	hsa-miR-664	CLIP-seq
MIRT2018283	hsa-miR-889	CLIP-seq
MIRT2018284	hsa-miR-891b	CLIP-seq
MIRT2018285	hsa-miR-944	CLIP-seq
MIRT2250113	hsa-miR-1229	CLIP-seq
MIRT2250114	hsa-miR-1273f	CLIP-seq
MIRT2250115	hsa-miR-143	CLIP-seq
MIRT1073850	hsa-miR-146a	CLIP-seq
MIRT1073851	hsa-miR-146b-5p	CLIP-seq
MIRT2250116	hsa-miR-197	CLIP-seq
MIRT2250117	hsa-miR-216b	CLIP-seq
MIRT1073863	hsa-miR-25	CLIP-seq
MIRT2250118	hsa-miR-298	CLIP-seq
MIRT2250119	hsa-miR-299-3p	CLIP-seq
MIRT1073865	hsa-miR-300	CLIP-seq
MIRT1073866	hsa-miR-3065-5p	CLIP-seq
MIRT2250120	hsa-miR-3119	CLIP-seq
MIRT2018239	hsa-miR-3120-5p	CLIP-seq
MIRT2250121	hsa-miR-3145-3p	CLIP-seq
MIRT2250122	hsa-miR-3154	CLIP-seq
MIRT2250123	hsa-miR-3163	CLIP-seq
MIRT2250124	hsa-miR-3180-5p	CLIP-seq
MIRT1073871	hsa-miR-32	CLIP-seq
MIRT1073872	hsa-miR-3200-3p	CLIP-seq
MIRT1073833	hsa-miR-331-5p	CLIP-seq
MIRT1073875	hsa-miR-340	CLIP-seq
MIRT2250125	hsa-miR-3619-3p	CLIP-seq
MIRT1073881	hsa-miR-363	CLIP-seq
MIRT1073884	hsa-miR-367	CLIP-seq
MIRT1073889	hsa-miR-381	CLIP-seq
MIRT2250126	hsa-miR-4287	CLIP-seq
MIRT2250127	hsa-miR-4293	CLIP-seq
MIRT2250128	hsa-miR-4307	CLIP-seq
MIRT1073897	hsa-miR-4325	CLIP-seq
MIRT2018247	hsa-miR-4457	CLIP-seq
MIRT2250129	hsa-miR-4461	CLIP-seq
MIRT2250130	hsa-miR-4469	CLIP-seq
MIRT2250131	hsa-miR-448	CLIP-seq
MIRT2018252	hsa-miR-4652-3p	CLIP-seq
MIRT2250132	hsa-miR-4659a-3p	CLIP-seq
MIRT2250133	hsa-miR-4659b-3p	CLIP-seq
MIRT1073909	hsa-miR-4666-3p	CLIP-seq
MIRT1073836	hsa-miR-4678	CLIP-seq
MIRT2250134	hsa-miR-4685-3p	CLIP-seq
MIRT2250135	hsa-miR-4687-5p	CLIP-seq
MIRT2018256	hsa-miR-4704-3p	CLIP-seq
MIRT2250136	hsa-miR-4708-5p	CLIP-seq
MIRT2250137	hsa-miR-4760-3p	CLIP-seq
MIRT2250138	hsa-miR-4762-5p	CLIP-seq
MIRT2250139	hsa-miR-4770	CLIP-seq
MIRT2250140	hsa-miR-4776-5p	CLIP-seq
MIRT2250141	hsa-miR-498	CLIP-seq
MIRT2018267	hsa-miR-513b	CLIP-seq
MIRT2018268	hsa-miR-515-5p	CLIP-seq
MIRT2018272	hsa-miR-548a-3p	CLIP-seq
MIRT2018273	hsa-miR-548e	CLIP-seq
MIRT2018274	hsa-miR-548f	CLIP-seq
MIRT2018279	hsa-miR-579	CLIP-seq
MIRT1073953	hsa-miR-580	CLIP-seq
MIRT1073954	hsa-miR-589	CLIP-seq
MIRT2018282	hsa-miR-664	CLIP-seq
MIRT1073961	hsa-miR-92a	CLIP-seq
MIRT1073962	hsa-miR-92b	CLIP-seq
MIRT2250142	hsa-miR-942	CLIP-seq
MIRT1073866	hsa-miR-3065-5p	CLIP-seq
MIRT1073949	hsa-miR-561	CLIP-seq
MIRT1073842	hsa-miR-1207-5p	CLIP-seq
MIRT2018233	hsa-miR-1258	CLIP-seq
MIRT1073844	hsa-miR-1273g	CLIP-seq
MIRT2553665	hsa-miR-1290	CLIP-seq
MIRT1073846	hsa-miR-1291	CLIP-seq
MIRT2553666	hsa-miR-135a	CLIP-seq
MIRT2553667	hsa-miR-135b	CLIP-seq
MIRT1073848	hsa-miR-137	CLIP-seq
MIRT2018235	hsa-miR-141	CLIP-seq
MIRT2018236	hsa-miR-150	CLIP-seq
MIRT1073852	hsa-miR-155	CLIP-seq
MIRT1073855	hsa-miR-194	CLIP-seq
MIRT2018237	hsa-miR-200a	CLIP-seq
MIRT1073860	hsa-miR-2113	CLIP-seq
MIRT2553668	hsa-miR-214	CLIP-seq
MIRT1073861	hsa-miR-219-1-3p	CLIP-seq
MIRT2553669	hsa-miR-2277-3p	CLIP-seq
MIRT1073863	hsa-miR-25	CLIP-seq
MIRT2250119	hsa-miR-299-3p	CLIP-seq
MIRT1073865	hsa-miR-300	CLIP-seq
MIRT1073866	hsa-miR-3065-5p	CLIP-seq
MIRT2018238	hsa-miR-3074-3p	CLIP-seq
MIRT2250120	hsa-miR-3119	CLIP-seq
MIRT2018239	hsa-miR-3120-5p	CLIP-seq
MIRT2250121	hsa-miR-3145-3p	CLIP-seq
MIRT2018241	hsa-miR-3152-5p	CLIP-seq
MIRT2018242	hsa-miR-3156-5p	CLIP-seq
MIRT2250123	hsa-miR-3163	CLIP-seq
MIRT2553670	hsa-miR-3164	CLIP-seq
MIRT2553671	hsa-miR-3167	CLIP-seq
MIRT1073870	hsa-miR-3174	CLIP-seq
MIRT2553672	hsa-miR-3185	CLIP-seq
MIRT1073871	hsa-miR-32	CLIP-seq
MIRT1073872	hsa-miR-3200-3p	CLIP-seq
MIRT1073873	hsa-miR-323-3p	CLIP-seq
MIRT1073874	hsa-miR-328	CLIP-seq
MIRT1073833	hsa-miR-331-5p	CLIP-seq
MIRT2553673	hsa-miR-338-5p	CLIP-seq
MIRT1073877	hsa-miR-3613-3p	CLIP-seq
MIRT1073878	hsa-miR-3614-5p	CLIP-seq
MIRT2018243	hsa-miR-361-5p	CLIP-seq
MIRT2553674	hsa-miR-3619-5p	CLIP-seq
MIRT1073881	hsa-miR-363	CLIP-seq
MIRT2553675	hsa-miR-3646	CLIP-seq
MIRT1073882	hsa-miR-365	CLIP-seq
MIRT1073883	hsa-miR-3662	CLIP-seq
MIRT1073884	hsa-miR-367	CLIP-seq
MIRT1073886	hsa-miR-371-5p	CLIP-seq
MIRT1073887	hsa-miR-371b-5p	CLIP-seq
MIRT1073889	hsa-miR-381	CLIP-seq
MIRT2018244	hsa-miR-3941	CLIP-seq
MIRT2553676	hsa-miR-3942-3p	CLIP-seq
MIRT2553677	hsa-miR-3978	CLIP-seq
MIRT1073891	hsa-miR-410	CLIP-seq
MIRT1073892	hsa-miR-4257	CLIP-seq
MIRT1073894	hsa-miR-4276	CLIP-seq
MIRT2018245	hsa-miR-4282	CLIP-seq
MIRT2553678	hsa-miR-4291	CLIP-seq
MIRT1073899	hsa-miR-4423-5p	CLIP-seq
MIRT2553679	hsa-miR-4474-3p	CLIP-seq
MIRT2018248	hsa-miR-4476	CLIP-seq
MIRT1073902	hsa-miR-4477a	CLIP-seq
MIRT2250131	hsa-miR-448	CLIP-seq
MIRT2553680	hsa-miR-4491	CLIP-seq
MIRT2553681	hsa-miR-4499	CLIP-seq
MIRT2553682	hsa-miR-4503	CLIP-seq
MIRT2018249	hsa-miR-450b-5p	CLIP-seq
MIRT2018250	hsa-miR-4528	CLIP-seq
MIRT1073908	hsa-miR-4637	CLIP-seq
MIRT2018251	hsa-miR-4643	CLIP-seq
MIRT2018252	hsa-miR-4652-3p	CLIP-seq
MIRT2553683	hsa-miR-4657	CLIP-seq
MIRT2250132	hsa-miR-4659a-3p	CLIP-seq
MIRT2250133	hsa-miR-4659b-3p	CLIP-seq
MIRT2018253	hsa-miR-466	CLIP-seq
MIRT1073909	hsa-miR-4666-3p	CLIP-seq
MIRT1073910	hsa-miR-4672	CLIP-seq
MIRT1073836	hsa-miR-4678	CLIP-seq
MIRT2553684	hsa-miR-4698	CLIP-seq
MIRT2018257	hsa-miR-4713-5p	CLIP-seq
MIRT2553685	hsa-miR-4715-3p	CLIP-seq
MIRT2553686	hsa-miR-4717-3p	CLIP-seq
MIRT1073912	hsa-miR-4720-3p	CLIP-seq
MIRT1073913	hsa-miR-4724-3p	CLIP-seq
MIRT2018258	hsa-miR-4727-5p	CLIP-seq
MIRT1073915	hsa-miR-4736	CLIP-seq
MIRT1073916	hsa-miR-4742-5p	CLIP-seq
MIRT2250138	hsa-miR-4762-5p	CLIP-seq
MIRT1073917	hsa-miR-4763-3p	CLIP-seq
MIRT2553687	hsa-miR-4766-3p	CLIP-seq
MIRT2018260	hsa-miR-4766-5p	CLIP-seq
MIRT2018261	hsa-miR-4769-3p	CLIP-seq
MIRT2553688	hsa-miR-4773	CLIP-seq
MIRT2018262	hsa-miR-4774-3p	CLIP-seq
MIRT2553689	hsa-miR-4776-3p	CLIP-seq
MIRT2018263	hsa-miR-4778-5p	CLIP-seq
MIRT2018264	hsa-miR-4789-3p	CLIP-seq
MIRT1073921	hsa-miR-4804-3p	CLIP-seq
MIRT1073922	hsa-miR-486-5p	CLIP-seq
MIRT1073923	hsa-miR-495	CLIP-seq
MIRT2553690	hsa-miR-500a	CLIP-seq
MIRT2018266	hsa-miR-507	CLIP-seq
MIRT1073925	hsa-miR-509-3p	CLIP-seq
MIRT2553691	hsa-miR-513c	CLIP-seq
MIRT2553692	hsa-miR-514b-5p	CLIP-seq
MIRT2018268	hsa-miR-515-5p	CLIP-seq
MIRT2018269	hsa-miR-520d-5p	CLIP-seq
MIRT2018270	hsa-miR-524-5p	CLIP-seq
MIRT2018271	hsa-miR-532-3p	CLIP-seq
MIRT2018272	hsa-miR-548a-3p	CLIP-seq
MIRT2018273	hsa-miR-548e	CLIP-seq
MIRT2018274	hsa-miR-548f	CLIP-seq
MIRT1073938	hsa-miR-548g	CLIP-seq
MIRT2018275	hsa-miR-548n	CLIP-seq
MIRT2018276	hsa-miR-548p	CLIP-seq
MIRT2018277	hsa-miR-557	CLIP-seq
MIRT1073949	hsa-miR-561	CLIP-seq
MIRT1073839	hsa-miR-569	CLIP-seq
MIRT1073952	hsa-miR-571	CLIP-seq
MIRT2018279	hsa-miR-579	CLIP-seq
MIRT1073955	hsa-miR-590-3p	CLIP-seq
MIRT2018282	hsa-miR-664	CLIP-seq
MIRT2553693	hsa-miR-761	CLIP-seq
MIRT2553694	hsa-miR-876-5p	CLIP-seq
MIRT2553695	hsa-miR-888	CLIP-seq
MIRT2018284	hsa-miR-891b	CLIP-seq
MIRT2553696	hsa-miR-922	CLIP-seq
MIRT1073961	hsa-miR-92a	CLIP-seq
MIRT1073962	hsa-miR-92b	CLIP-seq
MIRT2250142	hsa-miR-942	CLIP-seq
MIRT1073842	hsa-miR-1207-5p	CLIP-seq
MIRT2018233	hsa-miR-1258	CLIP-seq
MIRT2682983	hsa-miR-125a-3p	CLIP-seq
MIRT1073844	hsa-miR-1273g	CLIP-seq
MIRT1550308	hsa-miR-1276	CLIP-seq
MIRT2553665	hsa-miR-1290	CLIP-seq
MIRT1073846	hsa-miR-1291	CLIP-seq
MIRT2553666	hsa-miR-135a	CLIP-seq
MIRT2553667	hsa-miR-135b	CLIP-seq
MIRT1073848	hsa-miR-137	CLIP-seq
MIRT2018235	hsa-miR-141	CLIP-seq
MIRT2018236	hsa-miR-150	CLIP-seq
MIRT1073852	hsa-miR-155	CLIP-seq
MIRT1073855	hsa-miR-194	CLIP-seq
MIRT2018237	hsa-miR-200a	CLIP-seq
MIRT1073860	hsa-miR-2113	CLIP-seq
MIRT2553668	hsa-miR-214	CLIP-seq
MIRT1073861	hsa-miR-219-1-3p	CLIP-seq
MIRT2553669	hsa-miR-2277-3p	CLIP-seq
MIRT1073863	hsa-miR-25	CLIP-seq
MIRT2250119	hsa-miR-299-3p	CLIP-seq
MIRT1073865	hsa-miR-300	CLIP-seq
MIRT1073866	hsa-miR-3065-5p	CLIP-seq
MIRT2018238	hsa-miR-3074-3p	CLIP-seq
MIRT2250120	hsa-miR-3119	CLIP-seq
MIRT2018239	hsa-miR-3120-5p	CLIP-seq
MIRT2250121	hsa-miR-3145-3p	CLIP-seq
MIRT2018241	hsa-miR-3152-5p	CLIP-seq
MIRT2018242	hsa-miR-3156-5p	CLIP-seq
MIRT2250123	hsa-miR-3163	CLIP-seq
MIRT2553670	hsa-miR-3164	CLIP-seq
MIRT2553671	hsa-miR-3167	CLIP-seq
MIRT1073870	hsa-miR-3174	CLIP-seq
MIRT2553672	hsa-miR-3185	CLIP-seq
MIRT1073871	hsa-miR-32	CLIP-seq
MIRT1073872	hsa-miR-3200-3p	CLIP-seq
MIRT1073873	hsa-miR-323-3p	CLIP-seq
MIRT1073874	hsa-miR-328	CLIP-seq
MIRT1073833	hsa-miR-331-5p	CLIP-seq
MIRT1073877	hsa-miR-3613-3p	CLIP-seq
MIRT1073878	hsa-miR-3614-5p	CLIP-seq
MIRT2018243	hsa-miR-361-5p	CLIP-seq
MIRT2553674	hsa-miR-3619-5p	CLIP-seq
MIRT1073881	hsa-miR-363	CLIP-seq
MIRT2553675	hsa-miR-3646	CLIP-seq
MIRT1073882	hsa-miR-365	CLIP-seq
MIRT1073883	hsa-miR-3662	CLIP-seq
MIRT1073884	hsa-miR-367	CLIP-seq
MIRT1073886	hsa-miR-371-5p	CLIP-seq
MIRT1073887	hsa-miR-371b-5p	CLIP-seq
MIRT1073889	hsa-miR-381	CLIP-seq
MIRT2682984	hsa-miR-3934	CLIP-seq
MIRT2018244	hsa-miR-3941	CLIP-seq
MIRT2553677	hsa-miR-3978	CLIP-seq
MIRT1073891	hsa-miR-410	CLIP-seq
MIRT1073892	hsa-miR-4257	CLIP-seq
MIRT2682985	hsa-miR-4275	CLIP-seq
MIRT1073894	hsa-miR-4276	CLIP-seq
MIRT2018245	hsa-miR-4282	CLIP-seq
MIRT2553678	hsa-miR-4291	CLIP-seq
MIRT1073899	hsa-miR-4423-5p	CLIP-seq
MIRT2553679	hsa-miR-4474-3p	CLIP-seq
MIRT2018248	hsa-miR-4476	CLIP-seq
MIRT1073902	hsa-miR-4477a	CLIP-seq
MIRT2250131	hsa-miR-448	CLIP-seq
MIRT2553680	hsa-miR-4491	CLIP-seq
MIRT2553681	hsa-miR-4499	CLIP-seq
MIRT2553682	hsa-miR-4503	CLIP-seq
MIRT2018249	hsa-miR-450b-5p	CLIP-seq
MIRT2018250	hsa-miR-4528	CLIP-seq
MIRT1073908	hsa-miR-4637	CLIP-seq
MIRT2018251	hsa-miR-4643	CLIP-seq
MIRT2018252	hsa-miR-4652-3p	CLIP-seq
MIRT2553683	hsa-miR-4657	CLIP-seq
MIRT2250132	hsa-miR-4659a-3p	CLIP-seq
MIRT2250133	hsa-miR-4659b-3p	CLIP-seq
MIRT2018253	hsa-miR-466	CLIP-seq
MIRT1073909	hsa-miR-4666-3p	CLIP-seq
MIRT1073910	hsa-miR-4672	CLIP-seq
MIRT1073836	hsa-miR-4678	CLIP-seq
MIRT2553684	hsa-miR-4698	CLIP-seq
MIRT2018257	hsa-miR-4713-5p	CLIP-seq
MIRT2553686	hsa-miR-4717-3p	CLIP-seq
MIRT1073912	hsa-miR-4720-3p	CLIP-seq
MIRT1073913	hsa-miR-4724-3p	CLIP-seq
MIRT2018258	hsa-miR-4727-5p	CLIP-seq
MIRT1073914	hsa-miR-4731-3p	CLIP-seq
MIRT1073915	hsa-miR-4736	CLIP-seq
MIRT1073916	hsa-miR-4742-5p	CLIP-seq
MIRT2250138	hsa-miR-4762-5p	CLIP-seq
MIRT1073917	hsa-miR-4763-3p	CLIP-seq
MIRT2553687	hsa-miR-4766-3p	CLIP-seq
MIRT2018260	hsa-miR-4766-5p	CLIP-seq
MIRT2018261	hsa-miR-4769-3p	CLIP-seq
MIRT2553688	hsa-miR-4773	CLIP-seq
MIRT2018262	hsa-miR-4774-3p	CLIP-seq
MIRT2553689	hsa-miR-4776-3p	CLIP-seq
MIRT2018263	hsa-miR-4778-5p	CLIP-seq
MIRT2018264	hsa-miR-4789-3p	CLIP-seq
MIRT1073920	hsa-miR-4801	CLIP-seq
MIRT1073921	hsa-miR-4804-3p	CLIP-seq
MIRT1073922	hsa-miR-486-5p	CLIP-seq
MIRT1073923	hsa-miR-495	CLIP-seq
MIRT2553690	hsa-miR-500a	CLIP-seq
MIRT2018266	hsa-miR-507	CLIP-seq
MIRT1073925	hsa-miR-509-3p	CLIP-seq
MIRT2553691	hsa-miR-513c	CLIP-seq
MIRT2553692	hsa-miR-514b-5p	CLIP-seq
MIRT2018268	hsa-miR-515-5p	CLIP-seq
MIRT2018269	hsa-miR-520d-5p	CLIP-seq
MIRT2018270	hsa-miR-524-5p	CLIP-seq
MIRT2018271	hsa-miR-532-3p	CLIP-seq
MIRT2018272	hsa-miR-548a-3p	CLIP-seq
MIRT2018273	hsa-miR-548e	CLIP-seq
MIRT2018274	hsa-miR-548f	CLIP-seq
MIRT1073938	hsa-miR-548g	CLIP-seq
MIRT2018276	hsa-miR-548p	CLIP-seq
MIRT2018277	hsa-miR-557	CLIP-seq
MIRT1073949	hsa-miR-561	CLIP-seq
MIRT1073839	hsa-miR-569	CLIP-seq
MIRT1073952	hsa-miR-571	CLIP-seq
MIRT2018279	hsa-miR-579	CLIP-seq
MIRT1073955	hsa-miR-590-3p	CLIP-seq
MIRT2018282	hsa-miR-664	CLIP-seq
MIRT2553693	hsa-miR-761	CLIP-seq
MIRT2682986	hsa-miR-764	CLIP-seq
MIRT2553694	hsa-miR-876-5p	CLIP-seq
MIRT2553695	hsa-miR-888	CLIP-seq
MIRT2018284	hsa-miR-891b	CLIP-seq
MIRT2553696	hsa-miR-922	CLIP-seq
MIRT1073961	hsa-miR-92a	CLIP-seq
MIRT1073962	hsa-miR-92b	CLIP-seq
MIRT2250142	hsa-miR-942	CLIP-seq

Show/Hide all (6)

Transcription factor	Regulation	Reference
FOSL1	Repression	23319049
HOXD3	Unknown	14610084
JUND	Repression	23319049
SP1	Repression	23319049
SP1	Unknown	12136940
SP3	Unknown	12136940

123

Show/Hide all (123)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IBA
GO:0001525	Process	Angiogenesis	IEA
GO:0001525	Process	Angiogenesis	IEP	11866539
GO:0001568	Process	Blood vessel development	IEA
GO:0001570	Process	Vasculogenesis	IEA
GO:0001618	Function	Virus receptor activity	IEA
GO:0001704	Process	Formation of primary germ layer	IEA
GO:0001846	Function	Opsonin binding	IEA
GO:0001846	Function	Opsonin binding	ISS
GO:0001968	Function	Fibronectin binding	IDA	24658351
GO:0002020	Function	Protease binding	IDA	22505472
GO:0005080	Function	Protein kinase C binding	IEA
GO:0005080	Function	Protein kinase C binding	ISS
GO:0005102	Function	Signaling receptor binding	IEA
GO:0005178	Function	Integrin binding	IEA
GO:0005178	Function	Integrin binding	IPI	20826760
GO:0005515	Function	Protein binding	IPI	1694173, 2478219, 11546839, 11877390, 11884718, 12695522, 12807887, 15299032, 15611078, 16099422, 17158881, 17925226, 20639902, 21677751, 22178926, 24011356, 24658351, 25383667, 28534487, 31331973, 32814053, 37184585, 38016540
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA	21310825
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	NAS	11877390
GO:0005886	Component	Plasma membrane	TAS	2430295
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0005925	Component	Focal adhesion	IDA	17158881, 25063885, 29162887
GO:0005925	Component	Focal adhesion	IEA
GO:0007155	Process	Cell adhesion	IDA	10218736
GO:0007155	Process	Cell adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	IBA
GO:0007160	Process	Cell-matrix adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	IMP	7525578, 24658351
GO:0007160	Process	Cell-matrix adhesion	NAS	11877390, 11970960, 19693543
GO:0007204	Process	Positive regulation of cytosolic calcium ion concentration	IEA
GO:0007229	Process	Integrin-mediated signaling pathway	IBA
GO:0007229	Process	Integrin-mediated signaling pathway	IDA	11970960
GO:0007229	Process	Integrin-mediated signaling pathway	IEA
GO:0007229	Process	Integrin-mediated signaling pathway	IMP	26934001
GO:0007229	Process	Integrin-mediated signaling pathway	NAS	11877390, 19693543
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	19578119
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0008305	Component	Integrin complex	IDA	15215180
GO:0008305	Component	Integrin complex	IEA
GO:0008305	Component	Integrin complex	NAS	11877390
GO:0009888	Process	Tissue development	IEA
GO:0009897	Component	External side of plasma membrane	IEA
GO:0009986	Component	Cell surface	HDA	19581412, 23658023
GO:0009986	Component	Cell surface	IBA
GO:0009986	Component	Cell surface	IDA	1918072, 7525578, 19933311, 20563599, 21310825, 22505472, 23154389, 25063885
GO:0009986	Component	Cell surface	IEA
GO:0009986	Component	Cell surface	ISS
GO:0010745	Process	Negative regulation of macrophage derived foam cell differentiation	IMP	15215180
GO:0010888	Process	Negative regulation of lipid storage	IMP	15215180
GO:0010989	Process	Negative regulation of low-density lipoprotein particle clearance	IMP	15215180
GO:0015026	Function	Coreceptor activity	TAS	23125415
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	ISS
GO:0016477	Process	Cell migration	IEA
GO:0016477	Process	Cell migration	IMP	26934001
GO:0017134	Function	Fibroblast growth factor binding	IDA	18441324
GO:0019960	Function	C-X3-C chemokine binding	IDA	23125415
GO:0030335	Process	Positive regulation of cell migration	IEA
GO:0031258	Component	Lamellipodium membrane	IDA	25063885
GO:0031527	Component	Filopodium membrane	IDA	25063885
GO:0031528	Component	Microvillus membrane	IDA	25063885
GO:0031589	Process	Cell-substrate adhesion	IMP	19933311
GO:0031994	Function	Insulin-like growth factor I binding	IDA	19578119
GO:0032369	Process	Negative regulation of lipid transport	IMP	15215180
GO:0032587	Component	Ruffle membrane	IDA	25063885
GO:0033627	Process	Cell adhesion mediated by integrin	IDA	12807887, 17158881
GO:0033627	Process	Cell adhesion mediated by integrin	IEA
GO:0033690	Process	Positive regulation of osteoblast proliferation	IEA
GO:0034113	Process	Heterotypic cell-cell adhesion	IMP	20563599
GO:0034446	Process	Substrate adhesion-dependent cell spreading	IDA	24658351
GO:0034682	Component	Integrin alphav-beta1 complex	IBA
GO:0034682	Component	Integrin alphav-beta1 complex	IPI	25398877
GO:0034683	Component	Integrin alphav-beta3 complex	IDA	20826760, 22505472, 23726972, 24658351, 25063885, 31331973
GO:0034683	Component	Integrin alphav-beta3 complex	IEA
GO:0034683	Component	Integrin alphav-beta3 complex	IPI	11546839
GO:0034684	Component	Integrin alphav-beta5 complex	IDA	25063885
GO:0034684	Component	Integrin alphav-beta5 complex	IEA
GO:0034684	Component	Integrin alphav-beta5 complex	IPI	1694173
GO:0034685	Component	Integrin alphav-beta6 complex	IDA	22278742
GO:0034685	Component	Integrin alphav-beta6 complex	IEA
GO:0034685	Component	Integrin alphav-beta6 complex	IPI	25383667
GO:0034686	Component	Integrin alphav-beta8 complex	IBA
GO:0034686	Component	Integrin alphav-beta8 complex	IDA	1918072, 7525578, 22278742
GO:0034686	Component	Integrin alphav-beta8 complex	IPI	30061598
GO:0035313	Process	Wound healing, spreading of epidermal cells	NAS	19693543
GO:0035579	Component	Specific granule membrane	TAS
GO:0035866	Component	Alphav-beta3 integrin-PKCalpha complex	NAS	16014375
GO:0035867	Component	Alphav-beta3 integrin-IGF-1-IGF1R complex	IDA	19578119
GO:0035868	Component	Alphav-beta3 integrin-HMGB1 complex	IDA	20826760
GO:0035987	Process	Endodermal cell differentiation	IMP	23154389
GO:0038023	Function	Signaling receptor activity	IBA
GO:0038027	Process	Apolipoprotein A-I-mediated signaling pathway	IMP	23726972
GO:0038132	Function	Neuregulin binding	IDA	20682778
GO:0043277	Process	Apoptotic cell clearance	IEA
GO:0043277	Process	Apoptotic cell clearance	IGI	20826760
GO:0043277	Process	Apoptotic cell clearance	ISS
GO:0045335	Component	Phagocytic vesicle	TAS
GO:0045785	Process	Positive regulation of cell adhesion	IDA	10708943
GO:0046718	Process	Symbiont entry into host cell	IMP	25063885
GO:0046718	Process	Symbiont entry into host cell	TAS	10570297
GO:0046872	Function	Metal ion binding	IEA
GO:0050431	Function	Transforming growth factor beta binding	ISS
GO:0050748	Process	Negative regulation of lipoprotein metabolic process	IMP	15215180
GO:0050764	Process	Regulation of phagocytosis	IDA	10570297
GO:0050840	Function	Extracellular matrix binding	IDA	22505472
GO:0050919	Process	Negative chemotaxis	IMP	23726972
GO:0051057	Process	Positive regulation of small GTPase mediated signal transduction	IMP	26934001
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337, 23533145
GO:0070161	Component	Anchoring junction	IEA
GO:0070371	Process	ERK1 and ERK2 cascade	IEA
GO:0070371	Process	ERK1 and ERK2 cascade	ISS
GO:0070588	Process	Calcium ion transmembrane transport	IDA	18395422
GO:0071604	Process	Transforming growth factor beta production	IEA
GO:0085017	Process	Entry into host cell by a symbiont-containing vacuole	NAS	10570297
GO:0097192	Process	Extrinsic apoptotic signaling pathway in absence of ligand	IEA
GO:0097192	Process	Extrinsic apoptotic signaling pathway in absence of ligand	ISS
GO:0098609	Process	Cell-cell adhesion	IBA
GO:1902533	Process	Positive regulation of intracellular signal transduction	IMP	26934001
GO:1990430	Function	Extracellular matrix protein binding	IDA	7525578
GO:2000536	Process	Negative regulation of entry of bacterium into host cell	IDA	10570297
GO:2001237	Process	Negative regulation of extrinsic apoptotic signaling pathway	IMP	10708943

MIM	HGNC	e!Ensembl
193210	6150	ENSG00000138448

P06756

Protein name

Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]

Protein function

The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide ar

PDB

1JV2 , 1L5G , 1M1X , 1U8C , 3IJE , 4G1E , 4G1M , 4MMX , 4MMY , 4MMZ , 4O02 , 4UM8 , 4UM9 , 5FFG , 5FFO , 5NEM , 5NER , 5NET , 5NEU , 6AVQ , 6AVR , 6AVU , 6DJP , 6MK0 , 6MSL , 6MSU , 6NAJ , 6OM1 , 6OM2 , 6UJA , 6UJB , 6UJC , 7Y1T , 8IJ5 , 8TCF , 8TCG , 8VS6 , 8VSD , 8W30 , 8XEI , 8XEK , 8XEL , 8XEN , 8XER , 8XEZ , 8XF6 , 8XFG , 8XFO , 9CZ7 , 9CZA , 9CZD

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01839	FG-GAP	252 → 286	FG-GAP repeat	Repeat
PF01839	FG-GAP	306 → 348	FG-GAP repeat	Repeat
PF01839	FG-GAP	370 → 406	FG-GAP repeat	Repeat
PF08441	Integrin_alpha2	467 → 914	Integrin alpha	Family
PF00357	Integrin_alpha	1017 → 1031	Integrin alpha cytoplasmic region	Family

Sequence

MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSA
SSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKS
HQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD
GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQLAT
RTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGE
QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTK
LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQI
LEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVY
PSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRR
ALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAAD
TTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVK
AQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAG
TQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSP
DHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLY
ILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIH
TLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIE
FPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGF
FKRVRPPQEEQEREQLQPHENGEGNSET

Sequence length

1048

Interactions

View interactions

	KEGG		Reactome
	Hormone signaling Phagosome Efferocytosis PI3K-Akt signaling pathway Focal adhesion ECM-receptor interaction Cell adhesion molecules Regulation of actin cytoskeleton Cytoskeleton in muscle cells Thyroid hormone signaling pathway Human cytomegalovirus infection Human papillomavirus infection Pathways in cancer Proteoglycans in cancer Small cell lung cancer Hypertrophic cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Dilated cardiomyopathy Fluid shear stress and atherosclerosis		Cross-presentation of particulate exogenous antigens (phagosomes) Elastic fibre formation PECAM1 interactions Molecules associated with elastic fibres Integrin cell surface interactions Syndecan interactions ECM proteoglycans VEGFA-VEGFR2 Pathway Signal transduction by L1 Neutrophil degranulation

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
IMMUNE DYSREGULATION, NEURODEVELOPMENTAL DEFECTS, AND COLITIS	Pathogenic; Likely pathogenic	rs1357935457, rs1443125036, rs1688922276, rs2468408721	RCV005862551 RCV005862552 RCV005862553 RCV005862554
ITGAV deficiency	Pathogenic; Likely pathogenic	rs1357935457, rs1443125036, rs1688922276, rs2468408721	RCV004555913 RCV004555914 RCV004555916 RCV004556873

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
ITGAV-related disorder	Likely benign; Benign	rs146565475, rs2230615, rs200132922, rs2468390167, rs2468580638, rs200418625, rs199754402, rs749663033, rs140516074, rs1374520480, rs112803582	RCV003921579 RCV003931835 RCV003974599 RCV003982682 RCV003904456 RCV003904578 RCV003913978 RCV003949595 RCV003922020 RCV003971742 RCV003978232

Show/Hide Text Mining Associations (102)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acro Osteolysis	Stimulate	19369175
Adenocarcinoma	Associate	33110104
Adenoma	Associate	26749005
Aortic Root Aneurysm	Stimulate	33230159
Apical Hypertrophic Cardiomyopathy	Stimulate	35328555
Arteriovenous Malformations	Associate	31519800
Arthritis Rheumatoid	Associate	15345499, 17615072, 25150077, 28376277
Atherosclerosis	Associate	12099514, 24412187
Bone Cysts Aneurysmal	Associate	22330339
Brain Neoplasms	Associate	25093246, 26689941, 29053416
Breast Neoplasms	Associate	11724803, 12874388, 14691052, 16846534, 26657485, 28050799, 29464003, 29498809, 29752407, 35526305, 35763908
Calcinosis	Associate	36009051
Calcinosis Cutis	Associate	35526305
Carcinogenesis	Associate	19893992
Carcinoma Hepatocellular	Associate	19893992, 21909361, 23345412, 27145276, 29453316, 29669827, 30215728, 31684995, 36246403, 36429000, 37679418
Carcinoma Intraductal Noninfiltrating	Associate	35526305
Carcinoma Non Small Cell Lung	Associate	26918447, 29284478, 35545404
Carcinoma Ovarian Epithelial	Associate	21747684, 33099932
Carcinoma Pancreatic Ductal	Associate	35419611, 40520021
Carcinoma Papillary	Associate	25655629
Carcinoma Renal Cell	Associate	25655629, 33850477
Carotid Artery Diseases	Associate	24412187
Cartilage Diseases	Associate	9741315
Cholangiocarcinoma	Associate	38123132
Chronobiology Disorders	Associate	34161337
Colonic Neoplasms	Associate	11169447
Colorectal Neoplasms	Associate	20558745, 26674523, 29068474, 31831830, 35266011, 36303457
Coronary Disease	Associate	11869845
COVID 19	Associate	33413422, 34161337
Crohn Disease	Associate	33201212
Cysts	Inhibit	26056923
Dentigerous Cyst	Associate	19369175
Diabetes Mellitus Type 1	Associate	33083497, 36303457
Endometriosis	Associate	26056923
Epidermolysis Bullosa	Associate	1694890
Esophageal Squamous Cell Carcinoma	Associate	36813090
Fetal Growth Retardation	Associate	36193846
Fibrosis	Associate	34827680
Fuchs' Endothelial Dystrophy	Associate	11869845
Gastrointestinal Neoplasms	Associate	39690926
Glaucoma Neovascular	Stimulate	25041566
Glioblastoma	Associate	12881526, 19401596, 22655084, 38009896, 39394177
Glioma	Associate	11572856, 19033423, 19401596, 25093246
HIV Infections	Associate	12083833
HTLV I Infections	Associate	12083833
Hyperlipoproteinemia Type II	Associate	32938406
Hypertension	Associate	38367239
Hypoxia	Associate	30367545
Idiopathic Pulmonary Fibrosis	Associate	32000779
Infections	Associate	19920174
Infertility	Associate	12645863, 36303457
Inflammation	Associate	24412187, 25150077
Inflammatory Bowel Diseases	Associate	33201212
Kidney Neoplasms	Associate	25655629
Leukemia Myeloid Acute	Associate	27248172
Leukoplakia Hairy	Associate	10918561
Liver Cirrhosis	Associate	27164900
Lung Neoplasms	Associate	22081074, 22132110, 26449830, 26918447, 29053416
Marfan Syndrome	Stimulate	33230159
Medulloblastoma	Associate	38009896
Melanoma	Associate	10998134, 11553709, 1376331, 22773839, 24412090, 37460977, 7522323
Mesothelioma	Associate	36901697
Mesothelioma Malignant	Associate	24595274, 31212858
Metabolic Syndrome	Associate	35320805
Mouth Neoplasms	Associate	29937423, 36231010
Nasopharyngeal Carcinoma	Associate	24440971, 28613134, 36345604
Neoplasm Metastasis	Associate	12874388, 1376331, 18199623, 20926544, 24440971, 28613134, 29743605, 30691475, 31684995, 33514011, 34884541, 35419611, 35981899, 36871552, 38123132, 38171245, 8623914, 9846970 View all (3 more)
Neoplasm Metastasis	Inhibit	27311960
Neoplasm Metastasis	Stimulate	35526305
Neoplasms	Associate	11553709, 16283305, 16731529, 19259068, 19369175, 19755667, 20558745, 20563533, 20926544, 21427239, 22174684, 22248086, 23247073, 24737780, 25436977 View all (30 more)
Neoplasms	Stimulate	29743605
Neoplasms	Inhibit	35526305, 37375208
Neuroblastoma	Associate	8623914
Opitz GBBB Syndrome X Linked	Associate	39394177
Osteoarthritis	Associate	21953087, 22662110, 32964955
Osteoarthritis Knee	Associate	24886251
Osteopetrosis	Associate	15231021
Osteosarcoma	Associate	30691475, 34884541
Ovarian Diseases	Stimulate	35295989
Ovarian Neoplasms	Associate	21747684, 23725446, 27458161, 33155399, 33317907, 33723319, 35053353
Pancreatic Neoplasms	Associate	30367545, 35419611
Paroxysmal ventricular fibrillation	Associate	33693877
Peritonitis	Associate	20926544
Phyllodes Tumor	Associate	37240386
Plaque Atherosclerotic	Associate	32938406
Polycystic Kidney Autosomal Dominant	Associate	11422734
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	36944577
Priapism	Associate	17408468
Prostatic Neoplasms	Associate	22966907, 23559257, 24175814, 27058620, 28314844, 29743605, 33514011, 35682554, 37314749, 37862114
Pulmonary Disease Chronic Obstructive	Associate	39690926
Radiation Pneumonitis	Associate	26449830
Rupture	Associate	32938406
Sarcoma	Associate	30691475
Small Cell Lung Carcinoma	Associate	35927660
Squamous Cell Carcinoma of Head and Neck	Associate	27108184, 33476742
Stomach Neoplasms	Associate	34281542, 36613819, 37036489
Stroke	Associate	40596960
Thyroid Cancer Papillary	Stimulate	40423510
Triple Negative Breast Neoplasms	Associate	27484639, 35447298
Uterine Cervical Neoplasms	Stimulate	21239458
Uterine Cervical Neoplasms	Associate	35038961
Wounds and Injuries	Associate	11869845

ITGAV (integrin subunit alpha V)