Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	3619
Gene name	Inner centromere protein
Gene symbol	INCENP
Synonyms (NCBI Gene)	-
Chromosome	11
Chromosome location	11q12.3
Summary	In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and `passenger,` or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (

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SNP ID	Visualize variation	Clinical significance	Consequence
rs61893682	G>C	Likely-pathogenic	Coding sequence variant, missense variant

338

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021587	hsa-miR-142-3p	Microarray	17612493
MIRT025087	hsa-miR-181a-5p	Microarray	17612493
MIRT042486	hsa-miR-423-3p	CLASH	23622248
MIRT716934	hsa-miR-216a-5p	HITS-CLIP	19536157
MIRT709386	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT709385	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT709384	hsa-miR-6847-3p	HITS-CLIP	19536157
MIRT709383	hsa-miR-3622b-5p	HITS-CLIP	19536157
MIRT709382	hsa-miR-4467	HITS-CLIP	19536157
MIRT709381	hsa-miR-6770-3p	HITS-CLIP	19536157
MIRT709386	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT709385	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT709384	hsa-miR-6847-3p	HITS-CLIP	19536157
MIRT709383	hsa-miR-3622b-5p	HITS-CLIP	19536157
MIRT709382	hsa-miR-4467	HITS-CLIP	19536157
MIRT709381	hsa-miR-6770-3p	HITS-CLIP	19536157
MIRT550368	hsa-miR-4282	HITS-CLIP	23824327
MIRT550362	hsa-miR-4428	PAR-CLIP	20371350
MIRT550361	hsa-miR-5683	PAR-CLIP	20371350
MIRT550360	hsa-miR-4491	PAR-CLIP	20371350
MIRT550359	hsa-miR-4657	PAR-CLIP	20371350
MIRT131161	hsa-miR-299-3p	PAR-CLIP	20371350
MIRT550358	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT550357	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT550356	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT550355	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT550354	hsa-miR-185-5p	PAR-CLIP	20371350
MIRT550353	hsa-miR-4306	PAR-CLIP	20371350
MIRT550352	hsa-miR-4644	PAR-CLIP	20371350
MIRT550351	hsa-miR-4470	PAR-CLIP	20371350
MIRT550350	hsa-miR-5681b	PAR-CLIP	20371350
MIRT550349	hsa-miR-4536-5p	PAR-CLIP	20371350
MIRT550348	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT550347	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT550346	hsa-miR-182-5p	PAR-CLIP	20371350
MIRT550368	hsa-miR-4282	PAR-CLIP	20371350
MIRT131172	hsa-miR-548u	PAR-CLIP	20371350
MIRT131193	hsa-miR-7161-5p	PAR-CLIP	20371350
MIRT550368	hsa-miR-4282	PAR-CLIP	21572407
MIRT515486	hsa-miR-3123	PAR-CLIP	21572407
MIRT550367	hsa-miR-5584-5p	PAR-CLIP	21572407
MIRT550366	hsa-miR-6750-5p	PAR-CLIP	21572407
MIRT550365	hsa-miR-6822-5p	PAR-CLIP	21572407
MIRT515487	hsa-miR-9500	PAR-CLIP	21572407
MIRT515485	hsa-miR-135a-3p	PAR-CLIP	21572407
MIRT515484	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT515483	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT515482	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT515481	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT515480	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT515479	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT550364	hsa-miR-5003-5p	PAR-CLIP	21572407
MIRT550363	hsa-miR-3919	PAR-CLIP	21572407
MIRT515478	hsa-miR-4756-3p	PAR-CLIP	21572407
MIRT515477	hsa-miR-554	PAR-CLIP	21572407
MIRT515476	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT515475	hsa-miR-219a-2-3p	PAR-CLIP	21572407
MIRT515474	hsa-miR-3148	PAR-CLIP	21572407
MIRT515473	hsa-miR-4668-5p	PAR-CLIP	21572407
MIRT515472	hsa-miR-183-3p	PAR-CLIP	21572407
MIRT515471	hsa-miR-4452	PAR-CLIP	21572407
MIRT550362	hsa-miR-4428	PAR-CLIP	21572407
MIRT550361	hsa-miR-5683	PAR-CLIP	21572407
MIRT550360	hsa-miR-4491	PAR-CLIP	21572407
MIRT550359	hsa-miR-4657	PAR-CLIP	21572407
MIRT131161	hsa-miR-299-3p	PAR-CLIP	21572407
MIRT550358	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT550357	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT550356	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT550355	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT550354	hsa-miR-185-5p	PAR-CLIP	21572407
MIRT550353	hsa-miR-4306	PAR-CLIP	21572407
MIRT550352	hsa-miR-4644	PAR-CLIP	21572407
MIRT550351	hsa-miR-4470	PAR-CLIP	21572407
MIRT550350	hsa-miR-5681b	PAR-CLIP	21572407
MIRT550349	hsa-miR-4536-5p	PAR-CLIP	21572407
MIRT550348	hsa-let-7a-2-3p	PAR-CLIP	21572407
MIRT550347	hsa-let-7g-3p	PAR-CLIP	21572407
MIRT550346	hsa-miR-182-5p	PAR-CLIP	21572407
MIRT515486	hsa-miR-3123	PAR-CLIP	23446348
MIRT515487	hsa-miR-9500	PAR-CLIP	23446348
MIRT515485	hsa-miR-135a-3p	PAR-CLIP	23446348
MIRT515484	hsa-miR-25-3p	PAR-CLIP	23446348
MIRT515483	hsa-miR-32-5p	PAR-CLIP	23446348
MIRT515482	hsa-miR-363-3p	PAR-CLIP	23446348
MIRT515481	hsa-miR-367-3p	PAR-CLIP	23446348
MIRT515480	hsa-miR-92a-3p	PAR-CLIP	23446348
MIRT515479	hsa-miR-92b-3p	PAR-CLIP	23446348
MIRT515478	hsa-miR-4756-3p	PAR-CLIP	23446348
MIRT515477	hsa-miR-554	PAR-CLIP	23446348
MIRT515476	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT515475	hsa-miR-219a-2-3p	PAR-CLIP	23446348
MIRT515474	hsa-miR-3148	PAR-CLIP	23446348
MIRT515473	hsa-miR-4668-5p	PAR-CLIP	23446348
MIRT515472	hsa-miR-183-3p	PAR-CLIP	23446348
MIRT515471	hsa-miR-4452	PAR-CLIP	23446348
MIRT131172	hsa-miR-548u	PAR-CLIP	23446348
MIRT131193	hsa-miR-7161-5p	PAR-CLIP	23446348
MIRT495003	hsa-miR-520d-5p	PAR-CLIP	23708386
MIRT495002	hsa-miR-524-5p	PAR-CLIP	23708386
MIRT025087	hsa-miR-181a-5p	HITS-CLIP	22473208
MIRT131157	hsa-miR-181b-5p	HITS-CLIP	22473208
MIRT131158	hsa-miR-181c-5p	HITS-CLIP	22473208
MIRT131162	hsa-miR-181d-5p	HITS-CLIP	22473208
MIRT716934	hsa-miR-216a-5p	HITS-CLIP	19536157
MIRT709386	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT709385	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT709384	hsa-miR-6847-3p	HITS-CLIP	19536157
MIRT709383	hsa-miR-3622b-5p	HITS-CLIP	19536157
MIRT709382	hsa-miR-4467	HITS-CLIP	19536157
MIRT709381	hsa-miR-6770-3p	HITS-CLIP	19536157
MIRT709386	hsa-miR-24-1-5p	HITS-CLIP	19536157
MIRT709385	hsa-miR-24-2-5p	HITS-CLIP	19536157
MIRT709384	hsa-miR-6847-3p	HITS-CLIP	19536157
MIRT709383	hsa-miR-3622b-5p	HITS-CLIP	19536157
MIRT709382	hsa-miR-4467	HITS-CLIP	19536157
MIRT709381	hsa-miR-6770-3p	HITS-CLIP	19536157
MIRT550368	hsa-miR-4282	HITS-CLIP	23824327
MIRT550362	hsa-miR-4428	PAR-CLIP	20371350
MIRT550361	hsa-miR-5683	PAR-CLIP	20371350
MIRT550360	hsa-miR-4491	PAR-CLIP	20371350
MIRT550359	hsa-miR-4657	PAR-CLIP	20371350
MIRT131161	hsa-miR-299-3p	PAR-CLIP	20371350
MIRT550358	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT550357	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT550356	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT550355	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT550354	hsa-miR-185-5p	PAR-CLIP	20371350
MIRT550353	hsa-miR-4306	PAR-CLIP	20371350
MIRT550352	hsa-miR-4644	PAR-CLIP	20371350
MIRT550351	hsa-miR-4470	PAR-CLIP	20371350
MIRT550350	hsa-miR-5681b	PAR-CLIP	20371350
MIRT550349	hsa-miR-4536-5p	PAR-CLIP	20371350
MIRT550348	hsa-let-7a-2-3p	PAR-CLIP	20371350
MIRT550347	hsa-let-7g-3p	PAR-CLIP	20371350
MIRT550346	hsa-miR-182-5p	PAR-CLIP	20371350
MIRT550368	hsa-miR-4282	PAR-CLIP	20371350
MIRT131172	hsa-miR-548u	PAR-CLIP	20371350
MIRT131193	hsa-miR-7161-5p	PAR-CLIP	20371350
MIRT550368	hsa-miR-4282	PAR-CLIP	21572407
MIRT515486	hsa-miR-3123	PAR-CLIP	21572407
MIRT550367	hsa-miR-5584-5p	PAR-CLIP	21572407
MIRT550366	hsa-miR-6750-5p	PAR-CLIP	21572407
MIRT550365	hsa-miR-6822-5p	PAR-CLIP	21572407
MIRT515487	hsa-miR-9500	PAR-CLIP	21572407
MIRT515485	hsa-miR-135a-3p	PAR-CLIP	21572407
MIRT515484	hsa-miR-25-3p	PAR-CLIP	21572407
MIRT515483	hsa-miR-32-5p	PAR-CLIP	21572407
MIRT515482	hsa-miR-363-3p	PAR-CLIP	21572407
MIRT515481	hsa-miR-367-3p	PAR-CLIP	21572407
MIRT515480	hsa-miR-92a-3p	PAR-CLIP	21572407
MIRT515479	hsa-miR-92b-3p	PAR-CLIP	21572407
MIRT550364	hsa-miR-5003-5p	PAR-CLIP	21572407
MIRT550363	hsa-miR-3919	PAR-CLIP	21572407
MIRT515478	hsa-miR-4756-3p	PAR-CLIP	21572407
MIRT515477	hsa-miR-554	PAR-CLIP	21572407
MIRT515476	hsa-miR-219b-3p	PAR-CLIP	21572407
MIRT515475	hsa-miR-219a-2-3p	PAR-CLIP	21572407
MIRT515474	hsa-miR-3148	PAR-CLIP	21572407
MIRT515473	hsa-miR-4668-5p	PAR-CLIP	21572407
MIRT515472	hsa-miR-183-3p	PAR-CLIP	21572407
MIRT515471	hsa-miR-4452	PAR-CLIP	21572407
MIRT550362	hsa-miR-4428	PAR-CLIP	21572407
MIRT550361	hsa-miR-5683	PAR-CLIP	21572407
MIRT550360	hsa-miR-4491	PAR-CLIP	21572407
MIRT550359	hsa-miR-4657	PAR-CLIP	21572407
MIRT131161	hsa-miR-299-3p	PAR-CLIP	21572407
MIRT550358	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT550357	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT550356	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT550355	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT550354	hsa-miR-185-5p	PAR-CLIP	21572407
MIRT550353	hsa-miR-4306	PAR-CLIP	21572407
MIRT550352	hsa-miR-4644	PAR-CLIP	21572407
MIRT550351	hsa-miR-4470	PAR-CLIP	21572407
MIRT550350	hsa-miR-5681b	PAR-CLIP	21572407
MIRT550349	hsa-miR-4536-5p	PAR-CLIP	21572407
MIRT550348	hsa-let-7a-2-3p	PAR-CLIP	21572407
MIRT550347	hsa-let-7g-3p	PAR-CLIP	21572407
MIRT550346	hsa-miR-182-5p	PAR-CLIP	21572407
MIRT515486	hsa-miR-3123	PAR-CLIP	23446348
MIRT515487	hsa-miR-9500	PAR-CLIP	23446348
MIRT515485	hsa-miR-135a-3p	PAR-CLIP	23446348
MIRT515484	hsa-miR-25-3p	PAR-CLIP	23446348
MIRT515483	hsa-miR-32-5p	PAR-CLIP	23446348
MIRT515482	hsa-miR-363-3p	PAR-CLIP	23446348
MIRT515481	hsa-miR-367-3p	PAR-CLIP	23446348
MIRT515480	hsa-miR-92a-3p	PAR-CLIP	23446348
MIRT515479	hsa-miR-92b-3p	PAR-CLIP	23446348
MIRT515478	hsa-miR-4756-3p	PAR-CLIP	23446348
MIRT515477	hsa-miR-554	PAR-CLIP	23446348
MIRT515476	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT515475	hsa-miR-219a-2-3p	PAR-CLIP	23446348
MIRT515474	hsa-miR-3148	PAR-CLIP	23446348
MIRT515473	hsa-miR-4668-5p	PAR-CLIP	23446348
MIRT515472	hsa-miR-183-3p	PAR-CLIP	23446348
MIRT515471	hsa-miR-4452	PAR-CLIP	23446348
MIRT131172	hsa-miR-548u	PAR-CLIP	23446348
MIRT131193	hsa-miR-7161-5p	PAR-CLIP	23446348
MIRT495003	hsa-miR-520d-5p	PAR-CLIP	23708386
MIRT495002	hsa-miR-524-5p	PAR-CLIP	23708386
MIRT1066196	hsa-miR-3136-3p	CLIP-seq
MIRT1066197	hsa-miR-3184	CLIP-seq
MIRT1066198	hsa-miR-423-5p	CLIP-seq
MIRT1066199	hsa-miR-4802-5p	CLIP-seq
MIRT1066200	hsa-miR-510	CLIP-seq
MIRT1066201	hsa-miR-512-5p	CLIP-seq
MIRT1066202	hsa-miR-548v	CLIP-seq
MIRT1066203	hsa-miR-663b	CLIP-seq
MIRT1066204	hsa-miR-1252	CLIP-seq
MIRT1066205	hsa-miR-1324	CLIP-seq
MIRT1066206	hsa-miR-214	CLIP-seq
MIRT1066196	hsa-miR-3136-3p	CLIP-seq
MIRT1066207	hsa-miR-3619-5p	CLIP-seq
MIRT1066208	hsa-miR-421	CLIP-seq
MIRT1066209	hsa-miR-4635	CLIP-seq
MIRT1066210	hsa-miR-4690-5p	CLIP-seq
MIRT1066211	hsa-miR-4709-5p	CLIP-seq
MIRT1066212	hsa-miR-4802-3p	CLIP-seq
MIRT1066202	hsa-miR-548v	CLIP-seq
MIRT1066213	hsa-miR-761	CLIP-seq
MIRT1550149	hsa-miR-30a	CLIP-seq
MIRT1550150	hsa-miR-30b	CLIP-seq
MIRT1550151	hsa-miR-30c	CLIP-seq
MIRT1550152	hsa-miR-30d	CLIP-seq
MIRT1550153	hsa-miR-30e	CLIP-seq
MIRT2015812	hsa-miR-1226	CLIP-seq
MIRT2015813	hsa-miR-197	CLIP-seq
MIRT2015814	hsa-miR-2682	CLIP-seq
MIRT2015815	hsa-miR-3143	CLIP-seq
MIRT2015816	hsa-miR-3197	CLIP-seq
MIRT2015817	hsa-miR-3662	CLIP-seq
MIRT2015818	hsa-miR-376c	CLIP-seq
MIRT2015819	hsa-miR-3977	CLIP-seq
MIRT2015820	hsa-miR-412	CLIP-seq
MIRT2015821	hsa-miR-449c	CLIP-seq
MIRT2015822	hsa-miR-4514	CLIP-seq
MIRT2015823	hsa-miR-4660	CLIP-seq
MIRT2015824	hsa-miR-4692	CLIP-seq
MIRT2015825	hsa-miR-4733-3p	CLIP-seq
MIRT2015826	hsa-miR-513a-5p	CLIP-seq
MIRT2015827	hsa-miR-543	CLIP-seq
MIRT2015828	hsa-miR-634	CLIP-seq
MIRT2015829	hsa-miR-940	CLIP-seq
MIRT2248274	hsa-miR-103a	CLIP-seq
MIRT2248275	hsa-miR-107	CLIP-seq
MIRT2248276	hsa-miR-1184	CLIP-seq
MIRT2248277	hsa-miR-1205	CLIP-seq
MIRT1066204	hsa-miR-1252	CLIP-seq
MIRT2248278	hsa-miR-1286	CLIP-seq
MIRT2248279	hsa-miR-140-3p	CLIP-seq
MIRT2248280	hsa-miR-150	CLIP-seq
MIRT2248281	hsa-miR-181a	CLIP-seq
MIRT2248282	hsa-miR-181b	CLIP-seq
MIRT2248283	hsa-miR-181c	CLIP-seq
MIRT2248284	hsa-miR-181d	CLIP-seq
MIRT2248285	hsa-miR-1972	CLIP-seq
MIRT2248286	hsa-miR-2110	CLIP-seq
MIRT1066206	hsa-miR-214	CLIP-seq
MIRT2248287	hsa-miR-3120-5p	CLIP-seq
MIRT1066196	hsa-miR-3136-3p	CLIP-seq
MIRT2015815	hsa-miR-3143	CLIP-seq
MIRT2248288	hsa-miR-3151	CLIP-seq
MIRT2248289	hsa-miR-3158-5p	CLIP-seq
MIRT1066197	hsa-miR-3184	CLIP-seq
MIRT2015816	hsa-miR-3197	CLIP-seq
MIRT2248290	hsa-miR-3199	CLIP-seq
MIRT2248291	hsa-miR-346	CLIP-seq
MIRT1066207	hsa-miR-3619-5p	CLIP-seq
MIRT2015817	hsa-miR-3662	CLIP-seq
MIRT2248292	hsa-miR-3926	CLIP-seq
MIRT1066208	hsa-miR-421	CLIP-seq
MIRT1066198	hsa-miR-423-5p	CLIP-seq
MIRT2248293	hsa-miR-4252	CLIP-seq
MIRT2248294	hsa-miR-4262	CLIP-seq
MIRT2248295	hsa-miR-4271	CLIP-seq
MIRT2248296	hsa-miR-4283	CLIP-seq
MIRT2248297	hsa-miR-4288	CLIP-seq
MIRT2248298	hsa-miR-4290	CLIP-seq
MIRT2248299	hsa-miR-4446-3p	CLIP-seq
MIRT2248300	hsa-miR-4447	CLIP-seq
MIRT2248301	hsa-miR-4456	CLIP-seq
MIRT2248302	hsa-miR-4472	CLIP-seq
MIRT2248303	hsa-miR-4489	CLIP-seq
MIRT2248304	hsa-miR-4492	CLIP-seq
MIRT2248305	hsa-miR-4498	CLIP-seq
MIRT2248306	hsa-miR-4505	CLIP-seq
MIRT2015822	hsa-miR-4514	CLIP-seq
MIRT1066209	hsa-miR-4635	CLIP-seq
MIRT2248307	hsa-miR-4649-3p	CLIP-seq
MIRT2248308	hsa-miR-4667-5p	CLIP-seq
MIRT2248309	hsa-miR-4687-5p	CLIP-seq
MIRT1066210	hsa-miR-4690-5p	CLIP-seq
MIRT2015824	hsa-miR-4692	CLIP-seq
MIRT2248310	hsa-miR-4699-3p	CLIP-seq
MIRT2248311	hsa-miR-4700-5p	CLIP-seq
MIRT1066211	hsa-miR-4709-5p	CLIP-seq
MIRT2248312	hsa-miR-4715-3p	CLIP-seq
MIRT2248313	hsa-miR-4717-5p	CLIP-seq
MIRT2248314	hsa-miR-4722-3p	CLIP-seq
MIRT2248315	hsa-miR-4725-3p	CLIP-seq
MIRT2248316	hsa-miR-4740-5p	CLIP-seq
MIRT2248317	hsa-miR-4797-5p	CLIP-seq
MIRT1066199	hsa-miR-4802-5p	CLIP-seq
MIRT2248318	hsa-miR-491-5p	CLIP-seq
MIRT2015827	hsa-miR-543	CLIP-seq
MIRT2248319	hsa-miR-548s	CLIP-seq
MIRT1066202	hsa-miR-548v	CLIP-seq
MIRT2248320	hsa-miR-632	CLIP-seq
MIRT2248321	hsa-miR-661	CLIP-seq
MIRT1066203	hsa-miR-663b	CLIP-seq
MIRT1066213	hsa-miR-761	CLIP-seq
MIRT2248322	hsa-miR-762	CLIP-seq
MIRT2015829	hsa-miR-940	CLIP-seq
MIRT2389426	hsa-miR-101	CLIP-seq
MIRT2248276	hsa-miR-1184	CLIP-seq
MIRT2248277	hsa-miR-1205	CLIP-seq
MIRT2389427	hsa-miR-139-5p	CLIP-seq
MIRT2389428	hsa-miR-144	CLIP-seq
MIRT2248285	hsa-miR-1972	CLIP-seq
MIRT2248287	hsa-miR-3120-5p	CLIP-seq
MIRT2248289	hsa-miR-3158-5p	CLIP-seq
MIRT1066197	hsa-miR-3184	CLIP-seq
MIRT2248291	hsa-miR-346	CLIP-seq
MIRT1066198	hsa-miR-423-5p	CLIP-seq
MIRT2248297	hsa-miR-4288	CLIP-seq
MIRT2248303	hsa-miR-4489	CLIP-seq
MIRT2389429	hsa-miR-4508	CLIP-seq
MIRT2389430	hsa-miR-4532	CLIP-seq
MIRT2248310	hsa-miR-4699-3p	CLIP-seq
MIRT2248317	hsa-miR-4797-5p	CLIP-seq
MIRT1066199	hsa-miR-4802-5p	CLIP-seq
MIRT2389431	hsa-miR-514	CLIP-seq
MIRT2389432	hsa-miR-514b-3p	CLIP-seq
MIRT1066202	hsa-miR-548v	CLIP-seq
MIRT2389433	hsa-miR-549	CLIP-seq
MIRT2389434	hsa-miR-586	CLIP-seq
MIRT2248320	hsa-miR-632	CLIP-seq

Show/Hide all (48)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000278	Process	Mitotic cell cycle	NAS	17956729
GO:0000281	Process	Mitotic cytokinesis	IBA
GO:0000281	Process	Mitotic cytokinesis	IMP	16239925
GO:0000281	Process	Mitotic cytokinesis	NAS	17956729
GO:0000775	Component	Chromosome, centromeric region	IDA	11084331, 16239925
GO:0000775	Component	Chromosome, centromeric region	IEA
GO:0000776	Component	Kinetochore	IBA
GO:0000776	Component	Kinetochore	IDA	16760428
GO:0000776	Component	Kinetochore	IEA
GO:0000795	Component	Synaptonemal complex	IEA
GO:0000800	Component	Lateral element	IEA
GO:0000801	Component	Central element	IEA
GO:0005515	Function	Protein binding	IPI	9864353, 14610074, 16239925, 17099693, 17956729, 19357306, 20562864, 20739936, 21051298, 21225229, 21346195, 27332895, 29568061, 30021884, 32707033, 33961781, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005721	Component	Pericentric heterochromatin	IDA	9864353
GO:0005737	Component	Cytoplasm	IEA
GO:0005819	Component	Spindle	IDA	9864353
GO:0005819	Component	Spindle	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0007059	Process	Chromosome segregation	IEA
GO:0007059	Process	Chromosome segregation	IMP	16239925
GO:0010369	Component	Chromocenter	IEA
GO:0015630	Component	Microtubule cytoskeleton	IDA	9859993
GO:0016604	Component	Nuclear body	IDA
GO:0030496	Component	Midbody	IBA
GO:0030496	Component	Midbody	IDA
GO:0030496	Component	Midbody	IEA
GO:0032133	Component	Chromosome passenger complex	IBA
GO:0032133	Component	Chromosome passenger complex	IPI	17956729
GO:0032991	Component	Protein-containing complex	IDA	16239925
GO:0051256	Process	Mitotic spindle midzone assembly	NAS	17956729
GO:0051257	Process	Meiotic spindle midzone assembly	IBA
GO:0051301	Process	Cell division	IEA
GO:0051310	Process	Metaphase chromosome alignment	IBA
GO:0090267	Process	Positive regulation of mitotic cell cycle spindle assembly checkpoint	NAS	17956729
GO:0090307	Process	Mitotic spindle assembly	NAS	17956729
GO:0140677	Function	Molecular function activator activity	IPI	27332895
GO:1901970	Process	Positive regulation of mitotic sister chromatid separation	NAS	17956729
GO:1902425	Process	Positive regulation of attachment of mitotic spindle microtubules to kinetochore	NAS	17956729
GO:1903490	Process	Positive regulation of mitotic cytokinesis	NAS	17956729
GO:1990385	Component	Meiotic spindle midzone	IBA

MIM	HGNC	e!Ensembl
604411	6058	ENSG00000149503

Q9NQS7

Protein name

Inner centromere protein

Protein function

Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chrom

PDB

2QFA , 4AF3 , 5IEH , 5IEK , 6GR8 , 6GR9 , 6YIE , 6YIF , 6YIH , 8RUP , 9ESA

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12178	INCENP_N	6 → 41	Chromosome passenger complex (CPC) protein INCENP N terminal	Domain
PF03941	INCENP_ARK-bind	825 → 881	Inner centromere protein, ARK binding region	Family

Sequence

MGTTAPGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEAERMFTREFSKEPELMPKTP
SQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATVVGENGSV
LRRVTRAAAAAAAATMALAAPSSPTPESPTMLTKKPEDNHTQCQLVPVVEIGISERQNAE
QHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATP
QDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDS
QSVRHSPIAPSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLE
RLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPKPAAS
SPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPS
SPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQ
RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIE
QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH
QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA
EQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA
KEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPRK
PIPTWARGTPLSQAIIHQYYHPPNLLELFGTILPLDLEDIFKKSKPRYHKRTSSAVWNSP
PLQGARVPSSLAYSLKKH

Sequence length

918

Interactions

View interactions

	Reactome
			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Nephronophthisis	Likely pathogenic	rs61893682	RCV000662273

Show/Hide Unknown Diseases (13)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Acute myeloid leukemia	Benign	rs2958341, rs34441559, rs61893680	RCV005920169 RCV005923430 RCV005925121
Cervical cancer	Benign	rs2958341, rs34441559, rs61893680	RCV005920170 RCV005923432 RCV005925122
Cholangiocarcinoma	Benign	rs61893680	RCV005925127
Clear cell carcinoma of kidney	Benign	rs34441559	RCV005923433
Colon adenocarcinoma	Benign	rs116462742	RCV005904884
Gastric cancer	Benign	rs34441559, rs61893680	RCV005923434 RCV005925123
Hepatocellular carcinoma	Benign	rs34441559	RCV005923431
Lung cancer	Benign	rs2958341, rs61893680	RCV005920171 RCV005925128
Melanoma	Benign	rs34441559	RCV005923436
Ovarian serous cystadenocarcinoma	Benign	rs61893680	RCV005925124
Thymoma	Benign	rs34441559, rs61893680	RCV005923435 RCV005925126
Uterine carcinosarcoma	Benign	rs61893680	RCV005925125
Uterine corpus endometrial carcinoma	Benign	rs34441559, rs116462742	RCV005923437 RCV005904885

Show/Hide Text Mining Associations (9)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Aneuploidy	Associate	18752045
Breast Neoplasms	Associate	25586992
Carcinoma Hepatocellular	Associate	33540684, 33830865
Ciliopathies	Associate	26489029
Lymphoma B Cell	Associate	18752045
Neoplasms	Associate	26460953, 27432226, 31991041
Ovarian Neoplasms	Associate	27432226
Pancreatic Neoplasms	Associate	36401386
Prostatic Neoplasms	Associate	36901944

INCENP (inner centromere protein)