Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3608
Gene name Gene Name - the full gene name approved by the HGNC.	Interleukin enhancer binding factor 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ILF2
Synonyms (NCBI Gene) Gene synonyms aliases	NF45, PRO3063
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1q21.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa

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miRTarBase ID	miRNA	Experiments	Reference
MIRT022452	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT049906	hsa-miR-31-5p	CLASH	23622248
MIRT049279	hsa-miR-92a-3p	CLASH	23622248
MIRT047288	hsa-miR-181b-5p	CLASH	23622248
MIRT046275	hsa-miR-23b-3p	CLASH	23622248
MIRT045674	hsa-miR-149-5p	CLASH	23622248
MIRT043419	hsa-miR-331-3p	CLASH	23622248
MIRT042209	hsa-miR-484	CLASH	23622248
MIRT040442	hsa-miR-615-3p	CLASH	23622248
MIRT036602	hsa-miR-940	CLASH	23622248
MIRT1065429	hsa-miR-1	CLIP-seq
MIRT1065430	hsa-miR-1270	CLIP-seq
MIRT1065431	hsa-miR-1305	CLIP-seq
MIRT1065432	hsa-miR-1323	CLIP-seq
MIRT1065433	hsa-miR-206	CLIP-seq
MIRT1065434	hsa-miR-3120-3p	CLIP-seq
MIRT1065435	hsa-miR-3130-5p	CLIP-seq
MIRT1065436	hsa-miR-3143	CLIP-seq
MIRT1065437	hsa-miR-3180-5p	CLIP-seq
MIRT1065438	hsa-miR-3673	CLIP-seq
MIRT1065439	hsa-miR-3973	CLIP-seq
MIRT1065440	hsa-miR-421	CLIP-seq
MIRT1065441	hsa-miR-425	CLIP-seq
MIRT1065442	hsa-miR-4282	CLIP-seq
MIRT1065443	hsa-miR-4433	CLIP-seq
MIRT1065444	hsa-miR-4459	CLIP-seq
MIRT1065445	hsa-miR-4482	CLIP-seq
MIRT1065446	hsa-miR-4495	CLIP-seq
MIRT1065447	hsa-miR-4514	CLIP-seq
MIRT1065448	hsa-miR-4531	CLIP-seq
MIRT1065449	hsa-miR-4683	CLIP-seq
MIRT1065450	hsa-miR-4690-5p	CLIP-seq
MIRT1065451	hsa-miR-4692	CLIP-seq
MIRT1065452	hsa-miR-4709-5p	CLIP-seq
MIRT1065453	hsa-miR-4768-3p	CLIP-seq
MIRT1065454	hsa-miR-513a-3p	CLIP-seq
MIRT1065455	hsa-miR-513b	CLIP-seq
MIRT1065456	hsa-miR-520a-5p	CLIP-seq
MIRT1065457	hsa-miR-525-5p	CLIP-seq
MIRT1065458	hsa-miR-543	CLIP-seq
MIRT1065459	hsa-miR-545	CLIP-seq
MIRT1065460	hsa-miR-548l	CLIP-seq
MIRT1065461	hsa-miR-548o	CLIP-seq
MIRT1065462	hsa-miR-571	CLIP-seq
MIRT1065463	hsa-miR-613	CLIP-seq
MIRT1065464	hsa-miR-620	CLIP-seq
MIRT1065465	hsa-miR-654-3p	CLIP-seq
MIRT1065466	hsa-miR-662	CLIP-seq
MIRT1065467	hsa-miR-885-3p	CLIP-seq
MIRT1065429	hsa-miR-1	CLIP-seq
MIRT2015568	hsa-miR-1193	CLIP-seq
MIRT2015569	hsa-miR-1225-5p	CLIP-seq
MIRT1065430	hsa-miR-1270	CLIP-seq
MIRT1065431	hsa-miR-1305	CLIP-seq
MIRT2015570	hsa-miR-136	CLIP-seq
MIRT1065433	hsa-miR-206	CLIP-seq
MIRT2015571	hsa-miR-3074-5p	CLIP-seq
MIRT2015572	hsa-miR-3117-5p	CLIP-seq
MIRT1065434	hsa-miR-3120-3p	CLIP-seq
MIRT2015573	hsa-miR-3132	CLIP-seq
MIRT2015574	hsa-miR-3134	CLIP-seq
MIRT1065436	hsa-miR-3143	CLIP-seq
MIRT2015575	hsa-miR-3179	CLIP-seq
MIRT1065437	hsa-miR-3180-5p	CLIP-seq
MIRT2015576	hsa-miR-3189-3p	CLIP-seq
MIRT1065438	hsa-miR-3673	CLIP-seq
MIRT2015577	hsa-miR-3679-3p	CLIP-seq
MIRT2015578	hsa-miR-370	CLIP-seq
MIRT2015579	hsa-miR-3925-3p	CLIP-seq
MIRT1065439	hsa-miR-3973	CLIP-seq
MIRT2015580	hsa-miR-409-3p	CLIP-seq
MIRT1065440	hsa-miR-421	CLIP-seq
MIRT1065441	hsa-miR-425	CLIP-seq
MIRT1065443	hsa-miR-4433	CLIP-seq
MIRT1065444	hsa-miR-4459	CLIP-seq
MIRT1065446	hsa-miR-4495	CLIP-seq
MIRT2015581	hsa-miR-4496	CLIP-seq
MIRT1065447	hsa-miR-4514	CLIP-seq
MIRT2015582	hsa-miR-4528	CLIP-seq
MIRT1065448	hsa-miR-4531	CLIP-seq
MIRT2015583	hsa-miR-4653-3p	CLIP-seq
MIRT2015584	hsa-miR-4659a-3p	CLIP-seq
MIRT2015585	hsa-miR-4659b-3p	CLIP-seq
MIRT1065449	hsa-miR-4683	CLIP-seq
MIRT1065450	hsa-miR-4690-5p	CLIP-seq
MIRT2015586	hsa-miR-4691-5p	CLIP-seq
MIRT1065451	hsa-miR-4692	CLIP-seq
MIRT1065452	hsa-miR-4709-5p	CLIP-seq
MIRT2015587	hsa-miR-4733-5p	CLIP-seq
MIRT1065453	hsa-miR-4768-3p	CLIP-seq
MIRT2015588	hsa-miR-4781-3p	CLIP-seq
MIRT2015589	hsa-miR-4802-5p	CLIP-seq
MIRT1065455	hsa-miR-513b	CLIP-seq
MIRT1065456	hsa-miR-520a-5p	CLIP-seq
MIRT1065457	hsa-miR-525-5p	CLIP-seq
MIRT1065458	hsa-miR-543	CLIP-seq
MIRT1065459	hsa-miR-545	CLIP-seq
MIRT1065460	hsa-miR-548l	CLIP-seq
MIRT1065462	hsa-miR-571	CLIP-seq
MIRT1065463	hsa-miR-613	CLIP-seq
MIRT1065464	hsa-miR-620	CLIP-seq
MIRT1065465	hsa-miR-654-3p	CLIP-seq
MIRT1065466	hsa-miR-662	CLIP-seq
MIRT1065467	hsa-miR-885-3p	CLIP-seq
MIRT2015590	hsa-miR-885-5p	CLIP-seq
MIRT1065429	hsa-miR-1	CLIP-seq
MIRT2015568	hsa-miR-1193	CLIP-seq
MIRT1065430	hsa-miR-1270	CLIP-seq
MIRT1065431	hsa-miR-1305	CLIP-seq
MIRT1065432	hsa-miR-1323	CLIP-seq
MIRT2015570	hsa-miR-136	CLIP-seq
MIRT1065433	hsa-miR-206	CLIP-seq
MIRT2015571	hsa-miR-3074-5p	CLIP-seq
MIRT2015572	hsa-miR-3117-5p	CLIP-seq
MIRT1065434	hsa-miR-3120-3p	CLIP-seq
MIRT1065435	hsa-miR-3130-5p	CLIP-seq
MIRT2015574	hsa-miR-3134	CLIP-seq
MIRT1065436	hsa-miR-3143	CLIP-seq
MIRT1065437	hsa-miR-3180-5p	CLIP-seq
MIRT1065438	hsa-miR-3673	CLIP-seq
MIRT2015578	hsa-miR-370	CLIP-seq
MIRT2015579	hsa-miR-3925-3p	CLIP-seq
MIRT1065439	hsa-miR-3973	CLIP-seq
MIRT1065440	hsa-miR-421	CLIP-seq
MIRT1065441	hsa-miR-425	CLIP-seq
MIRT1065443	hsa-miR-4433	CLIP-seq
MIRT1065444	hsa-miR-4459	CLIP-seq
MIRT2247879	hsa-miR-4463	CLIP-seq
MIRT1065445	hsa-miR-4482	CLIP-seq
MIRT1065446	hsa-miR-4495	CLIP-seq
MIRT1065447	hsa-miR-4514	CLIP-seq
MIRT2015582	hsa-miR-4528	CLIP-seq
MIRT1065448	hsa-miR-4531	CLIP-seq
MIRT2015583	hsa-miR-4653-3p	CLIP-seq
MIRT2015584	hsa-miR-4659a-3p	CLIP-seq
MIRT2015585	hsa-miR-4659b-3p	CLIP-seq
MIRT1065449	hsa-miR-4683	CLIP-seq
MIRT1065450	hsa-miR-4690-5p	CLIP-seq
MIRT2015586	hsa-miR-4691-5p	CLIP-seq
MIRT1065451	hsa-miR-4692	CLIP-seq
MIRT1065452	hsa-miR-4709-5p	CLIP-seq
MIRT2247880	hsa-miR-4719	CLIP-seq
MIRT2015587	hsa-miR-4733-5p	CLIP-seq
MIRT1065453	hsa-miR-4768-3p	CLIP-seq
MIRT2015589	hsa-miR-4802-5p	CLIP-seq
MIRT1065455	hsa-miR-513b	CLIP-seq
MIRT1065456	hsa-miR-520a-5p	CLIP-seq
MIRT1065457	hsa-miR-525-5p	CLIP-seq
MIRT1065458	hsa-miR-543	CLIP-seq
MIRT1065459	hsa-miR-545	CLIP-seq
MIRT1065460	hsa-miR-548l	CLIP-seq
MIRT1065461	hsa-miR-548o	CLIP-seq
MIRT1065462	hsa-miR-571	CLIP-seq
MIRT1065463	hsa-miR-613	CLIP-seq
MIRT1065464	hsa-miR-620	CLIP-seq
MIRT1065467	hsa-miR-885-3p	CLIP-seq
MIRT2015590	hsa-miR-885-5p	CLIP-seq
MIRT1065443	hsa-miR-4433	CLIP-seq
MIRT1065444	hsa-miR-4459	CLIP-seq
MIRT1065446	hsa-miR-4495	CLIP-seq
MIRT1065450	hsa-miR-4690-5p	CLIP-seq
MIRT1065453	hsa-miR-4768-3p	CLIP-seq
MIRT1065429	hsa-miR-1	CLIP-seq
MIRT2015569	hsa-miR-1225-5p	CLIP-seq
MIRT1065432	hsa-miR-1323	CLIP-seq
MIRT1065433	hsa-miR-206	CLIP-seq
MIRT2015571	hsa-miR-3074-5p	CLIP-seq
MIRT2015572	hsa-miR-3117-5p	CLIP-seq
MIRT1065435	hsa-miR-3130-5p	CLIP-seq
MIRT2015573	hsa-miR-3132	CLIP-seq
MIRT2015575	hsa-miR-3179	CLIP-seq
MIRT2015576	hsa-miR-3189-3p	CLIP-seq
MIRT1065438	hsa-miR-3673	CLIP-seq
MIRT2015577	hsa-miR-3679-3p	CLIP-seq
MIRT2015578	hsa-miR-370	CLIP-seq
MIRT2015579	hsa-miR-3925-3p	CLIP-seq
MIRT1065441	hsa-miR-425	CLIP-seq
MIRT1065445	hsa-miR-4482	CLIP-seq
MIRT1065446	hsa-miR-4495	CLIP-seq
MIRT2015581	hsa-miR-4496	CLIP-seq
MIRT1065447	hsa-miR-4514	CLIP-seq
MIRT2015583	hsa-miR-4653-3p	CLIP-seq
MIRT2015584	hsa-miR-4659a-3p	CLIP-seq
MIRT2015585	hsa-miR-4659b-3p	CLIP-seq
MIRT1065450	hsa-miR-4690-5p	CLIP-seq
MIRT1065451	hsa-miR-4692	CLIP-seq
MIRT2015587	hsa-miR-4733-5p	CLIP-seq
MIRT2015589	hsa-miR-4802-5p	CLIP-seq
MIRT1065461	hsa-miR-548o	CLIP-seq
MIRT1065463	hsa-miR-613	CLIP-seq
MIRT1065465	hsa-miR-654-3p	CLIP-seq
MIRT1065466	hsa-miR-662	CLIP-seq
MIRT1065467	hsa-miR-885-3p	CLIP-seq
MIRT1065429	hsa-miR-1	CLIP-seq
MIRT2015569	hsa-miR-1225-5p	CLIP-seq
MIRT1065432	hsa-miR-1323	CLIP-seq
MIRT1065433	hsa-miR-206	CLIP-seq
MIRT2015571	hsa-miR-3074-5p	CLIP-seq
MIRT2015572	hsa-miR-3117-5p	CLIP-seq
MIRT1065435	hsa-miR-3130-5p	CLIP-seq
MIRT2015573	hsa-miR-3132	CLIP-seq
MIRT2015575	hsa-miR-3179	CLIP-seq
MIRT2015576	hsa-miR-3189-3p	CLIP-seq
MIRT1065438	hsa-miR-3673	CLIP-seq
MIRT2015577	hsa-miR-3679-3p	CLIP-seq
MIRT2015578	hsa-miR-370	CLIP-seq
MIRT2015579	hsa-miR-3925-3p	CLIP-seq
MIRT1065441	hsa-miR-425	CLIP-seq
MIRT1065445	hsa-miR-4482	CLIP-seq
MIRT1065446	hsa-miR-4495	CLIP-seq
MIRT2015581	hsa-miR-4496	CLIP-seq
MIRT1065447	hsa-miR-4514	CLIP-seq
MIRT2015583	hsa-miR-4653-3p	CLIP-seq
MIRT2015584	hsa-miR-4659a-3p	CLIP-seq
MIRT2015585	hsa-miR-4659b-3p	CLIP-seq
MIRT1065450	hsa-miR-4690-5p	CLIP-seq
MIRT1065451	hsa-miR-4692	CLIP-seq
MIRT2015587	hsa-miR-4733-5p	CLIP-seq
MIRT2015589	hsa-miR-4802-5p	CLIP-seq
MIRT1065461	hsa-miR-548o	CLIP-seq
MIRT1065463	hsa-miR-613	CLIP-seq
MIRT1065465	hsa-miR-654-3p	CLIP-seq
MIRT1065466	hsa-miR-662	CLIP-seq
MIRT1065467	hsa-miR-885-3p	CLIP-seq

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IBA
GO:0003677	Function	DNA binding	IDA	7519613, 10574923, 11804788
GO:0003677	Function	DNA binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003725	Function	Double-stranded RNA binding	IBA
GO:0003725	Function	Double-stranded RNA binding	IDA	10574923
GO:0005515	Function	Protein binding	IPI	9442054, 10574923, 11739746, 17289661, 21146485, 32296183
GO:0005576	Component	Extracellular region	HDA	27068509
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	IDA	7519613, 21123651
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA	11790298
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0035580	Component	Specific granule lumen	TAS
GO:0045893	Process	Positive regulation of DNA-templated transcription	IBA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	11739746
GO:1904724	Component	Tertiary granule lumen	TAS
GO:1904813	Component	Ficolin-1-rich granule lumen	TAS
GO:1990904	Component	Ribonucleoprotein complex	IDA	17289661

MIM	HGNC	e!Ensembl
603181	6037	ENSG00000143621

Protein

UniProt ID

Q12905

Protein name

Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa)

Protein function

Chromatin-interacting protein that forms a stable heterodimer with interleukin enhancer-binding factor 3/ILF3 and plays a role in several biological processes including transcription, innate immunity or cell growth (PubMed:18458058, PubMed:31212

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07528	DZF	104 → 338	DZF domain	Domain

Sequence

MRGDRGRGRGGRFGSRGGPGGGFRPFVPHIPFDFYLCEMAFPRVKPAPDETSFSEALLKR
NQDLAPNSAEQASILSLVTKINNVIDNLIVAPGTFEVQIEEVRQVGSYKKGTMTTGHNVA
DLVVILKILPTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITTV
PPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPL
TPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGLFLPGSVGITDPCESGNFRVHT
VMTLEQQDMVCYTAQTLVRILSHGGFRKILGQEGDASYLASEISTWDGVIVTPSEKAYEK
PPEKKEGEEEEENTEEPPQGEEEESMETQE

Sequence length

390

Interactions

View interactions

	Reactome
			Neutrophil degranulation

ILF2 (interleukin enhancer binding factor 2)