IL5RA (interleukin 5 receptor subunit alpha)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
3568 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Interleukin 5 receptor subunit alpha |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
IL5RA |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
CD125, CDw125, HSIL5R3, IL5R |
|
Chromosome
Chromosome number
|
3 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
3p26.2 |
|
Summary
Summary of gene provided in NCBI Entrez Gene.
|
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
| Transcription factors | |||||||||||||||||||
|
|||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||
| UniProt ID | Q01344 | ||||||||||
| Protein name | Interleukin-5 receptor subunit alpha (IL-5 receptor subunit alpha) (IL-5R subunit alpha) (IL-5R-alpha) (IL-5RA) (CDw125) (CD antigen CD125) | ||||||||||
| Protein function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:9378992). Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1 | ||||||||||
| PDB | 1OBX , 1OBZ , 3QT2 , 3VA2 , 6H41 , 8TLD | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Expressed on eosinophils and basophils. | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 420 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|