IL5RA (interleukin 5 receptor subunit alpha)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 3568 |
| Gene name | Interleukin 5 receptor subunit alpha |
| Gene symbol | IL5RA |
| Synonyms (NCBI Gene) |
CD125CDw125HSIL5R3IL5R
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| Chromosome | 3 |
| Chromosome location | 3p26.2 |
| Summary | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), |
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miRNA
miRNA information provided by mirtarbase database.
500
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
7
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q01344 | ||||||||||
| Protein name | Interleukin-5 receptor subunit alpha (IL-5 receptor subunit alpha) (IL-5R subunit alpha) (IL-5R-alpha) (IL-5RA) (CDw125) (CD antigen CD125) | ||||||||||
| Protein function | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:9378992). Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed:1 | ||||||||||
| PDB | 1OBX , 1OBZ , 3QT2 , 3VA2 , 6H41 , 8TLD | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed on eosinophils and basophils. | ||||||||||
| Sequence |
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| Sequence length | 420 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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