Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	332
Gene name	Baculoviral IAP repeat containing 5
Gene symbol	BIRC5
Synonyms (NCBI Gene)	API4EPR-1
Chromosome	17
Chromosome location	17q25.3
Summary	This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes pro

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005363	hsa-miR-542-3p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	20728447
MIRT006046	hsa-miR-218-5p	ImmunoblotLuciferase reporter assayMicroarrayqRT-PCR	21385904
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	22306317
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	22306317
MIRT006046	hsa-miR-218-5p	ImmunoblotLuciferase reporter assayMicroarrayqRT-PCR	21385904
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	22306317
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	22306317
MIRT006046	hsa-miR-218-5p	ImmunoblotLuciferase reporter assayMicroarrayqRT-PCR	21385904
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006141	hsa-miR-708-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	21852381
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	22306317
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	22306317
MIRT006256	hsa-miR-203a-3p	Western blot	22886454
MIRT007304	hsa-miR-335-5p	Luciferase reporter assay	23232114
MIRT007304	hsa-miR-335-5p	Luciferase reporter assay	23232114
MIRT007304	hsa-miR-335-5p	Luciferase reporter assay	23232114
MIRT016656	hsa-miR-425-5p	Sequencing	20371350
MIRT025591	hsa-miR-10a-5p	Sequencing	20371350
MIRT027310	hsa-miR-101-3p	Sequencing	20371350
MIRT052024	hsa-let-7b-5p	CLASH	23622248
MIRT048806	hsa-miR-93-5p	CLASH	23622248
MIRT047940	hsa-miR-30c-5p	CLASH	23622248
MIRT045690	hsa-miR-149-5p	CLASH	23622248
MIRT041728	hsa-miR-484	CLASH	23622248
MIRT036530	hsa-miR-1226-3p	CLASH	23622248
MIRT036054	hsa-miR-1301-3p	CLASH	23622248
MIRT053499	hsa-miR-34a-5p	qRT-PCRWestern blot	23264087
MIRT053499	hsa-miR-34a-5p	FlowqRT-PCRWestern blot	24068565
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assayqRT-PCRWestern blot	22713668
MIRT054417	hsa-miR-195-5p	Luciferase reporter assayqRT-PCR	24520312
MIRT054419	hsa-miR-497-5p	Luciferase reporter assayWestern blot	24520312
MIRT054633	hsa-miR-150-5p	ImmunohistochemistryIn situ hybridizationMicroarrayqRT-PCRWestern blot	24613688
MIRT054909	hsa-miR-16-5p	ImmunoblotLuciferase reporter assayqRT-PCR	23380758
MIRT006256	hsa-miR-203a-3p	FlowLuciferase reporter assayqRT-PCRWestern blot	23073851
MIRT006256	hsa-miR-203a-3p	FlowLuciferase reporter assayqRT-PCRWestern blot	23073851
MIRT509851	hsa-miR-3622a-3p	HITS-CLIP	19536157
MIRT509850	hsa-miR-3622b-3p	HITS-CLIP	19536157
MIRT345987	hsa-miR-6765-3p	HITS-CLIP	19536157
MIRT611547	hsa-miR-1248	HITS-CLIP	19536157
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	19536157
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	19536157
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	19536157
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	19536157
MIRT611546	hsa-miR-4469	HITS-CLIP	19536157
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT611544	hsa-miR-4297	HITS-CLIP	19536157
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	19536157
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	19536157
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT611547	hsa-miR-1248	HITS-CLIP	23824327
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT611546	hsa-miR-4469	HITS-CLIP	23824327
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT611544	hsa-miR-4297	HITS-CLIP	23824327
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT611547	hsa-miR-1248	HITS-CLIP	23824327
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT611546	hsa-miR-4469	HITS-CLIP	23824327
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT611544	hsa-miR-4297	HITS-CLIP	23824327
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT611548	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT611547	hsa-miR-1248	HITS-CLIP	23824327
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT611546	hsa-miR-4469	HITS-CLIP	23824327
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT611544	hsa-miR-4297	HITS-CLIP	23824327
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT289431	hsa-miR-3662	PAR-CLIP	20371350
MIRT564042	hsa-miR-4311	PAR-CLIP	20371350
MIRT289429	hsa-miR-1252-3p	PAR-CLIP	20371350
MIRT564041	hsa-miR-3943	PAR-CLIP	20371350
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT289427	hsa-miR-1225-3p	PAR-CLIP	20371350
MIRT564040	hsa-miR-1233-3p	PAR-CLIP	20371350
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	20371350
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	20371350
MIRT079072	hsa-miR-4778-5p	PAR-CLIP	20371350
MIRT079067	hsa-miR-26a-1-3p	PAR-CLIP	20371350
MIRT079068	hsa-miR-26a-2-3p	PAR-CLIP	20371350
MIRT564039	hsa-miR-4677-3p	PAR-CLIP	20371350
MIRT564038	hsa-miR-4679	PAR-CLIP	20371350
MIRT513157	hsa-miR-3119	PAR-CLIP	20371350
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	20371350
MIRT513156	hsa-miR-636	PAR-CLIP	20371350
MIRT006046	hsa-miR-218-5p	PAR-CLIP	20371350
MIRT079069	hsa-miR-2113	PAR-CLIP	20371350
MIRT289461	hsa-miR-3940-3p	PAR-CLIP	20371350
MIRT509853	hsa-miR-1323	PAR-CLIP	20371350
MIRT509852	hsa-miR-548o-3p	PAR-CLIP	20371350
MIRT509851	hsa-miR-3622a-3p	PAR-CLIP	20371350
MIRT509850	hsa-miR-3622b-3p	PAR-CLIP	20371350
MIRT345987	hsa-miR-6765-3p	PAR-CLIP	20371350
MIRT345983	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT345985	hsa-miR-6511a-3p	PAR-CLIP	20371350
MIRT345986	hsa-miR-6511b-3p	PAR-CLIP	20371350
MIRT345988	hsa-miR-6784-3p	PAR-CLIP	20371350
MIRT345989	hsa-miR-6862-3p	PAR-CLIP	20371350
MIRT345984	hsa-miR-4490	PAR-CLIP	20371350
MIRT345981	hsa-miR-1229-3p	PAR-CLIP	20371350
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	20371350
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	20371350
MIRT513157	hsa-miR-3119	PAR-CLIP	20371350
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	20371350
MIRT513156	hsa-miR-636	PAR-CLIP	20371350
MIRT006046	hsa-miR-218-5p	PAR-CLIP	20371350
MIRT079069	hsa-miR-2113	PAR-CLIP	20371350
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	20371350
MIRT079080	hsa-miR-646	PAR-CLIP	20371350
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT079077	hsa-miR-485-5p	PAR-CLIP	20371350
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	20371350
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	20371350
MIRT079084	hsa-miR-3135b	PAR-CLIP	20371350
MIRT079079	hsa-miR-504-3p	PAR-CLIP	20371350
MIRT524753	hsa-miR-122-5p	PAR-CLIP	20371350
MIRT079082	hsa-miR-3652	PAR-CLIP	20371350
MIRT079083	hsa-miR-4430	PAR-CLIP	20371350
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	20371350
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	21572407
MIRT079080	hsa-miR-646	PAR-CLIP	21572407
MIRT079077	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	21572407
MIRT079084	hsa-miR-3135b	PAR-CLIP	21572407
MIRT079079	hsa-miR-504-3p	PAR-CLIP	21572407
MIRT524753	hsa-miR-122-5p	PAR-CLIP	21572407
MIRT079082	hsa-miR-3652	PAR-CLIP	21572407
MIRT079083	hsa-miR-4430	PAR-CLIP	21572407
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	21572407
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	21572407
MIRT513157	hsa-miR-3119	PAR-CLIP	21572407
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	21572407
MIRT513156	hsa-miR-636	PAR-CLIP	21572407
MIRT006046	hsa-miR-218-5p	PAR-CLIP	21572407
MIRT079069	hsa-miR-2113	PAR-CLIP	21572407
MIRT289436	hsa-miR-936	PAR-CLIP	22012620
MIRT079065	hsa-miR-4716-5p	PAR-CLIP	22012620
MIRT530753	hsa-miR-2053	PAR-CLIP	22012620
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	23446348
MIRT079080	hsa-miR-646	PAR-CLIP	23446348
MIRT079077	hsa-miR-485-5p	PAR-CLIP	23446348
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	23446348
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	23446348
MIRT079084	hsa-miR-3135b	PAR-CLIP	23446348
MIRT079079	hsa-miR-504-3p	PAR-CLIP	23446348
MIRT524753	hsa-miR-122-5p	PAR-CLIP	23446348
MIRT079082	hsa-miR-3652	PAR-CLIP	23446348
MIRT079083	hsa-miR-4430	PAR-CLIP	23446348
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	23446348
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	23446348
MIRT513157	hsa-miR-3119	PAR-CLIP	23446348
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	23446348
MIRT513156	hsa-miR-636	PAR-CLIP	23446348
MIRT006046	hsa-miR-218-5p	PAR-CLIP	23446348
MIRT079069	hsa-miR-2113	PAR-CLIP	23446348
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	23446348
MIRT079080	hsa-miR-646	PAR-CLIP	23446348
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	23446348
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	23446348
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT289461	hsa-miR-3940-3p	PAR-CLIP	23446348
MIRT509853	hsa-miR-1323	PAR-CLIP	23446348
MIRT509852	hsa-miR-548o-3p	PAR-CLIP	23446348
MIRT509851	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT509850	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT345987	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT345983	hsa-miR-1247-3p	PAR-CLIP	23446348
MIRT345985	hsa-miR-6511a-3p	PAR-CLIP	23446348
MIRT345986	hsa-miR-6511b-3p	PAR-CLIP	23446348
MIRT345988	hsa-miR-6784-3p	PAR-CLIP	23446348
MIRT345989	hsa-miR-6862-3p	PAR-CLIP	23446348
MIRT345984	hsa-miR-4490	PAR-CLIP	23446348
MIRT345981	hsa-miR-1229-3p	PAR-CLIP	23446348
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	23446348
MIRT079080	hsa-miR-646	PAR-CLIP	23446348
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	23446348
MIRT079077	hsa-miR-485-5p	PAR-CLIP	23446348
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	23446348
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	23446348
MIRT079084	hsa-miR-3135b	PAR-CLIP	23446348
MIRT079082	hsa-miR-3652	PAR-CLIP	23446348
MIRT079083	hsa-miR-4430	PAR-CLIP	23446348
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT006046	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT006046	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT005363	hsa-miR-542-3p	qRT-PCRLuciferase reporter assayWestern blot	25046253
MIRT053499	hsa-miR-34a-5p	qRT-PCRLuciferase reporter assayImmunohistochemistryWestern blot	25436980
MIRT053499	hsa-miR-34a-5p	qRT-PCRLuciferase reporter assayImmunohistochemistryWestern blot	25436980
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	26847520
MIRT006256	hsa-miR-203a-3p	Luciferase reporter assay	26847520
MIRT007304	hsa-miR-335-5p	FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot	26318298
MIRT007304	hsa-miR-335-5p	FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot	26318298
MIRT053499	hsa-miR-34a-5p	FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot	26318298
MIRT053499	hsa-miR-34a-5p	FlowLuciferase reporter assayMicroarrayqRT-PCRWestern blot	26318298
MIRT345992	hsa-miR-214-3p	ImmunoblotLuciferase reporter assayqRT-PCR	26234674
MIRT345992	hsa-miR-214-3p	ImmunoblotLuciferase reporter assayqRT-PCR	26234674
MIRT345992	hsa-miR-214-3p	ImmunoblotLuciferase reporter assayqRT-PCR	26234674
MIRT345992	hsa-miR-214-3p	ImmunoblotLuciferase reporter assayqRT-PCR	26234674
MIRT005363	hsa-miR-542-3p	FlowqRT-PCRWestern blot	26711968
MIRT053499	hsa-miR-34a-5p	PCR array	28097098
MIRT006046	hsa-miR-218-5p	Luciferase reporter assayqRT-PCRWestern blot	26442524
MIRT006046	hsa-miR-218-5p	Luciferase reporter assayqRT-PCRWestern blot	26442524
MIRT006046	hsa-miR-218-5p	Luciferase reporter assayqRT-PCRWestern blot	26442524
MIRT006046	hsa-miR-218-5p	Luciferase reporter assayqRT-PCRWestern blot	26442524
MIRT006046	hsa-miR-218-5p	Luciferase reporter assayqRT-PCRWestern blot	25900794
MIRT027310	hsa-miR-101-3p	Microarray	31638931
MIRT732975	hsa-miR-139-5p	Flow cytometryRNA-seq	33562636
MIRT732975	hsa-miR-139-5p	Flow cytometryRNA-seq	33562636
MIRT005363	hsa-miR-542-3p	Flow cytometryRNA-seq	33562636
MIRT509851	hsa-miR-3622a-3p	HITS-CLIP	19536157
MIRT509850	hsa-miR-3622b-3p	HITS-CLIP	19536157
MIRT345987	hsa-miR-6765-3p	HITS-CLIP	19536157
MIRT611547	hsa-miR-1248	HITS-CLIP	19536157
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	19536157
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	19536157
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	19536157
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	19536157
MIRT611546	hsa-miR-4469	HITS-CLIP	19536157
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT611544	hsa-miR-4297	HITS-CLIP	19536157
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	19536157
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	19536157
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	19536157
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	19536157
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	19536157
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT611547	hsa-miR-1248	HITS-CLIP	23824327
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT611546	hsa-miR-4469	HITS-CLIP	23824327
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT611544	hsa-miR-4297	HITS-CLIP	23824327
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT611547	hsa-miR-1248	HITS-CLIP	23824327
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT611546	hsa-miR-4469	HITS-CLIP	23824327
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT611544	hsa-miR-4297	HITS-CLIP	23824327
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT611548	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT611547	hsa-miR-1248	HITS-CLIP	23824327
MIRT345985	hsa-miR-6511a-3p	HITS-CLIP	23824327
MIRT345986	hsa-miR-6511b-3p	HITS-CLIP	23824327
MIRT345988	hsa-miR-6784-3p	HITS-CLIP	23824327
MIRT345989	hsa-miR-6862-3p	HITS-CLIP	23824327
MIRT611546	hsa-miR-4469	HITS-CLIP	23824327
MIRT611545	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT611544	hsa-miR-4297	HITS-CLIP	23824327
MIRT611543	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT611542	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT611541	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT611540	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT345981	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611539	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT289431	hsa-miR-3662	PAR-CLIP	20371350
MIRT564042	hsa-miR-4311	PAR-CLIP	20371350
MIRT289429	hsa-miR-1252-3p	PAR-CLIP	20371350
MIRT564041	hsa-miR-3943	PAR-CLIP	20371350
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT289427	hsa-miR-1225-3p	PAR-CLIP	20371350
MIRT564040	hsa-miR-1233-3p	PAR-CLIP	20371350
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	20371350
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	20371350
MIRT079072	hsa-miR-4778-5p	PAR-CLIP	20371350
MIRT079067	hsa-miR-26a-1-3p	PAR-CLIP	20371350
MIRT079068	hsa-miR-26a-2-3p	PAR-CLIP	20371350
MIRT564039	hsa-miR-4677-3p	PAR-CLIP	20371350
MIRT564038	hsa-miR-4679	PAR-CLIP	20371350
MIRT513157	hsa-miR-3119	PAR-CLIP	20371350
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	20371350
MIRT513156	hsa-miR-636	PAR-CLIP	20371350
MIRT006046	hsa-miR-218-5p	PAR-CLIP	20371350
MIRT079069	hsa-miR-2113	PAR-CLIP	20371350
MIRT289461	hsa-miR-3940-3p	PAR-CLIP	20371350
MIRT509853	hsa-miR-1323	PAR-CLIP	20371350
MIRT509852	hsa-miR-548o-3p	PAR-CLIP	20371350
MIRT509851	hsa-miR-3622a-3p	PAR-CLIP	20371350
MIRT509850	hsa-miR-3622b-3p	PAR-CLIP	20371350
MIRT345987	hsa-miR-6765-3p	PAR-CLIP	20371350
MIRT345983	hsa-miR-1247-3p	PAR-CLIP	20371350
MIRT345985	hsa-miR-6511a-3p	PAR-CLIP	20371350
MIRT345986	hsa-miR-6511b-3p	PAR-CLIP	20371350
MIRT345988	hsa-miR-6784-3p	PAR-CLIP	20371350
MIRT345989	hsa-miR-6862-3p	PAR-CLIP	20371350
MIRT345984	hsa-miR-4490	PAR-CLIP	20371350
MIRT345981	hsa-miR-1229-3p	PAR-CLIP	20371350
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	20371350
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	20371350
MIRT513157	hsa-miR-3119	PAR-CLIP	20371350
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	20371350
MIRT513156	hsa-miR-636	PAR-CLIP	20371350
MIRT006046	hsa-miR-218-5p	PAR-CLIP	20371350
MIRT079069	hsa-miR-2113	PAR-CLIP	20371350
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	20371350
MIRT079080	hsa-miR-646	PAR-CLIP	20371350
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT079077	hsa-miR-485-5p	PAR-CLIP	20371350
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	20371350
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	20371350
MIRT079084	hsa-miR-3135b	PAR-CLIP	20371350
MIRT079079	hsa-miR-504-3p	PAR-CLIP	20371350
MIRT524753	hsa-miR-122-5p	PAR-CLIP	20371350
MIRT079082	hsa-miR-3652	PAR-CLIP	20371350
MIRT079083	hsa-miR-4430	PAR-CLIP	20371350
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	20371350
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	21572407
MIRT079080	hsa-miR-646	PAR-CLIP	21572407
MIRT079077	hsa-miR-485-5p	PAR-CLIP	21572407
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	21572407
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	21572407
MIRT079084	hsa-miR-3135b	PAR-CLIP	21572407
MIRT079079	hsa-miR-504-3p	PAR-CLIP	21572407
MIRT524753	hsa-miR-122-5p	PAR-CLIP	21572407
MIRT079082	hsa-miR-3652	PAR-CLIP	21572407
MIRT079083	hsa-miR-4430	PAR-CLIP	21572407
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	21572407
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	21572407
MIRT513157	hsa-miR-3119	PAR-CLIP	21572407
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	21572407
MIRT513156	hsa-miR-636	PAR-CLIP	21572407
MIRT006046	hsa-miR-218-5p	PAR-CLIP	21572407
MIRT079069	hsa-miR-2113	PAR-CLIP	21572407
MIRT289436	hsa-miR-936	PAR-CLIP	22012620
MIRT079065	hsa-miR-4716-5p	PAR-CLIP	22012620
MIRT530753	hsa-miR-2053	PAR-CLIP	22012620
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	23446348
MIRT079080	hsa-miR-646	PAR-CLIP	23446348
MIRT079077	hsa-miR-485-5p	PAR-CLIP	23446348
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	23446348
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	23446348
MIRT079084	hsa-miR-3135b	PAR-CLIP	23446348
MIRT079079	hsa-miR-504-3p	PAR-CLIP	23446348
MIRT524753	hsa-miR-122-5p	PAR-CLIP	23446348
MIRT079082	hsa-miR-3652	PAR-CLIP	23446348
MIRT079083	hsa-miR-4430	PAR-CLIP	23446348
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT289437	hsa-miR-135a-5p	PAR-CLIP	23446348
MIRT289438	hsa-miR-135b-5p	PAR-CLIP	23446348
MIRT513157	hsa-miR-3119	PAR-CLIP	23446348
MIRT079071	hsa-miR-4703-3p	PAR-CLIP	23446348
MIRT513156	hsa-miR-636	PAR-CLIP	23446348
MIRT006046	hsa-miR-218-5p	PAR-CLIP	23446348
MIRT079069	hsa-miR-2113	PAR-CLIP	23446348
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	23446348
MIRT079080	hsa-miR-646	PAR-CLIP	23446348
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	23446348
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	23446348
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT289461	hsa-miR-3940-3p	PAR-CLIP	23446348
MIRT509853	hsa-miR-1323	PAR-CLIP	23446348
MIRT509852	hsa-miR-548o-3p	PAR-CLIP	23446348
MIRT509851	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT509850	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT345987	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT345983	hsa-miR-1247-3p	PAR-CLIP	23446348
MIRT345985	hsa-miR-6511a-3p	PAR-CLIP	23446348
MIRT345986	hsa-miR-6511b-3p	PAR-CLIP	23446348
MIRT345988	hsa-miR-6784-3p	PAR-CLIP	23446348
MIRT345989	hsa-miR-6862-3p	PAR-CLIP	23446348
MIRT345984	hsa-miR-4490	PAR-CLIP	23446348
MIRT345981	hsa-miR-1229-3p	PAR-CLIP	23446348
MIRT504613	hsa-miR-4797-5p	PAR-CLIP	23446348
MIRT079080	hsa-miR-646	PAR-CLIP	23446348
MIRT079081	hsa-miR-3613-3p	PAR-CLIP	23446348
MIRT079077	hsa-miR-485-5p	PAR-CLIP	23446348
MIRT079088	hsa-miR-6884-5p	PAR-CLIP	23446348
MIRT504612	hsa-miR-1911-5p	PAR-CLIP	23446348
MIRT079084	hsa-miR-3135b	PAR-CLIP	23446348
MIRT079082	hsa-miR-3652	PAR-CLIP	23446348
MIRT079083	hsa-miR-4430	PAR-CLIP	23446348
MIRT079086	hsa-miR-6792-5p	PAR-CLIP	23446348
MIRT821579	hsa-miR-103a	CLIP-seq
MIRT821580	hsa-miR-106a	CLIP-seq
MIRT821581	hsa-miR-106b	CLIP-seq
MIRT821582	hsa-miR-107	CLIP-seq
MIRT821583	hsa-miR-1184	CLIP-seq
MIRT821584	hsa-miR-1208	CLIP-seq
MIRT821585	hsa-miR-122	CLIP-seq
MIRT821586	hsa-miR-1233	CLIP-seq
MIRT821587	hsa-miR-1234	CLIP-seq
MIRT821588	hsa-miR-1288	CLIP-seq
MIRT821589	hsa-miR-17	CLIP-seq
MIRT821590	hsa-miR-181a	CLIP-seq
MIRT821591	hsa-miR-181b	CLIP-seq
MIRT821592	hsa-miR-181c	CLIP-seq
MIRT821593	hsa-miR-181d	CLIP-seq
MIRT821594	hsa-miR-1911	CLIP-seq
MIRT821595	hsa-miR-1913	CLIP-seq
MIRT821596	hsa-miR-198	CLIP-seq
MIRT821597	hsa-miR-20a	CLIP-seq
MIRT821598	hsa-miR-20b	CLIP-seq
MIRT821599	hsa-miR-2277-3p	CLIP-seq
MIRT821600	hsa-miR-3065-5p	CLIP-seq
MIRT821601	hsa-miR-3120-3p	CLIP-seq
MIRT821602	hsa-miR-3144-5p	CLIP-seq
MIRT821603	hsa-miR-3190	CLIP-seq
MIRT821604	hsa-miR-3194-3p	CLIP-seq
MIRT821605	hsa-miR-3202	CLIP-seq
MIRT821606	hsa-miR-324-3p	CLIP-seq
MIRT821607	hsa-miR-3609	CLIP-seq
MIRT821608	hsa-miR-361-3p	CLIP-seq
MIRT821609	hsa-miR-3647-3p	CLIP-seq
MIRT821610	hsa-miR-3649	CLIP-seq
MIRT821611	hsa-miR-3661	CLIP-seq
MIRT821612	hsa-miR-3688-5p	CLIP-seq
MIRT821613	hsa-miR-3691-3p	CLIP-seq
MIRT821614	hsa-miR-377	CLIP-seq
MIRT821615	hsa-miR-409-3p	CLIP-seq
MIRT821616	hsa-miR-4262	CLIP-seq
MIRT821617	hsa-miR-4318	CLIP-seq
MIRT821618	hsa-miR-4420	CLIP-seq
MIRT821619	hsa-miR-4470	CLIP-seq
MIRT821620	hsa-miR-4477a	CLIP-seq
MIRT821621	hsa-miR-4480	CLIP-seq
MIRT821622	hsa-miR-4486	CLIP-seq
MIRT821623	hsa-miR-4504	CLIP-seq
MIRT821624	hsa-miR-4519	CLIP-seq
MIRT821625	hsa-miR-4533	CLIP-seq
MIRT821626	hsa-miR-4676-5p	CLIP-seq
MIRT821627	hsa-miR-4690-3p	CLIP-seq
MIRT821628	hsa-miR-4695-3p	CLIP-seq
MIRT821629	hsa-miR-4706	CLIP-seq
MIRT821630	hsa-miR-4709-5p	CLIP-seq
MIRT821631	hsa-miR-4729	CLIP-seq
MIRT821632	hsa-miR-4749-5p	CLIP-seq
MIRT821633	hsa-miR-4781-5p	CLIP-seq
MIRT821634	hsa-miR-4796-3p	CLIP-seq
MIRT821635	hsa-miR-492	CLIP-seq
MIRT821636	hsa-miR-495	CLIP-seq
MIRT821637	hsa-miR-519d	CLIP-seq
MIRT821638	hsa-miR-544	CLIP-seq
MIRT821639	hsa-miR-545	CLIP-seq
MIRT821640	hsa-miR-548ah	CLIP-seq
MIRT821641	hsa-miR-548o	CLIP-seq
MIRT821642	hsa-miR-548p	CLIP-seq
MIRT821643	hsa-miR-575	CLIP-seq
MIRT821644	hsa-miR-631	CLIP-seq
MIRT821645	hsa-miR-642b	CLIP-seq
MIRT821646	hsa-miR-760	CLIP-seq
MIRT821647	hsa-miR-93	CLIP-seq
MIRT821648	hsa-miR-335	CLIP-seq
MIRT821609	hsa-miR-3647-3p	CLIP-seq
MIRT821649	hsa-miR-4735-5p	CLIP-seq
MIRT821650	hsa-miR-494	CLIP-seq
MIRT821585	hsa-miR-122	CLIP-seq
MIRT1942871	hsa-miR-1229	CLIP-seq
MIRT821594	hsa-miR-1911	CLIP-seq
MIRT1942872	hsa-miR-218	CLIP-seq
MIRT1942873	hsa-miR-3120-5p	CLIP-seq
MIRT1942874	hsa-miR-3145-3p	CLIP-seq
MIRT1942875	hsa-miR-3689a-5p	CLIP-seq
MIRT1942876	hsa-miR-3689b	CLIP-seq
MIRT1942877	hsa-miR-3689e	CLIP-seq
MIRT1942878	hsa-miR-3689f	CLIP-seq
MIRT1942879	hsa-miR-4475	CLIP-seq
MIRT1942880	hsa-miR-4719	CLIP-seq
MIRT821636	hsa-miR-495	CLIP-seq
MIRT821638	hsa-miR-544	CLIP-seq
MIRT1942881	hsa-miR-548aa	CLIP-seq
MIRT1942882	hsa-miR-548ac	CLIP-seq
MIRT1942883	hsa-miR-548d-3p	CLIP-seq
MIRT1942884	hsa-miR-548z	CLIP-seq
MIRT821645	hsa-miR-642b	CLIP-seq
MIRT1942871	hsa-miR-1229	CLIP-seq
MIRT1942885	hsa-miR-520a-5p	CLIP-seq
MIRT1942886	hsa-miR-525-5p	CLIP-seq
MIRT821584	hsa-miR-1208	CLIP-seq
MIRT821585	hsa-miR-122	CLIP-seq
MIRT2181627	hsa-miR-136	CLIP-seq
MIRT821594	hsa-miR-1911	CLIP-seq
MIRT1942873	hsa-miR-3120-5p	CLIP-seq
MIRT2181628	hsa-miR-3173-5p	CLIP-seq
MIRT2181629	hsa-miR-3664-5p	CLIP-seq
MIRT2181630	hsa-miR-4522	CLIP-seq
MIRT2181631	hsa-miR-4530	CLIP-seq
MIRT821627	hsa-miR-4690-3p	CLIP-seq
MIRT1942880	hsa-miR-4719	CLIP-seq
MIRT821636	hsa-miR-495	CLIP-seq
MIRT821638	hsa-miR-544	CLIP-seq
MIRT2181632	hsa-miR-634	CLIP-seq
MIRT821645	hsa-miR-642b	CLIP-seq
MIRT821585	hsa-miR-122	CLIP-seq
MIRT821594	hsa-miR-1911	CLIP-seq
MIRT2384788	hsa-miR-4252	CLIP-seq
MIRT1942880	hsa-miR-4719	CLIP-seq
MIRT821645	hsa-miR-642b	CLIP-seq

Show/Hide all (32)

Transcription factor	Regulation	Reference
APC	Unknown	11751382
CTNNB1	Unknown	19662654;19778454
DNMT1	Repression	17124180
E2F1	Activation	17848598;19102934
E2F1	Repression	19102934
E2F1	Unknown	23449974
E2F4	Unknown	18504435
EHMT2	Unknown	17124180
EP300	Activation	19102934
EP300	Repression	19102934
FOXO3	Unknown	22056878
HDAC1	Unknown	17124180
ILF3	Activation	22442257
KLF4	Repression	19361279
KLF5	Activation	16595680
LEF1	Unknown	19620402
MYCN	Activation	22703967
NFKB1	Activation	17553314
NFKB1	Unknown	14739605;20126979
RB1	Unknown	18504435
RELA	Activation	17553314
RELA	Unknown	14739605;20126979
SP1	Unknown	17124180;22334592
SP3	Unknown	22334592
SP4	Unknown	22334592
STAT3	Activation	15184887;16651438;17880940;19284568;19880237
STAT3	Unknown	15469392;20826784;21344490
TCF4	Unknown	19131553;19662654;19778454
TCF7L2	Activation	20331626
TP53	Repression	17124180
TP53	Unknown	19067706
TP73	Unknown	19067706

Show/Hide all (78)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	IDA	9859993
GO:0000228	Component	Nuclear chromosome	IDA	16322459
GO:0000278	Process	Mitotic cell cycle	NAS	17956729
GO:0000278	Process	Mitotic cell cycle	TAS	16291752
GO:0000281	Process	Mitotic cytokinesis	IBA
GO:0000281	Process	Mitotic cytokinesis	IMP	12805209
GO:0000281	Process	Mitotic cytokinesis	NAS	17956729
GO:0000775	Component	Chromosome, centromeric region	IDA	11084331, 11516652, 16291752, 16322459
GO:0000775	Component	Chromosome, centromeric region	IEA
GO:0000776	Component	Kinetochore	IBA
GO:0000776	Component	Kinetochore	IDA	15665297
GO:0000776	Component	Kinetochore	IEA
GO:0004869	Function	Cysteine-type endopeptidase inhibitor activity	IEA
GO:0005515	Function	Protein binding	IPI	11069302, 11516652, 12773388, 14610074, 15628841, 15665297, 16239925, 16291752, 17099693, 17681274, 17956729, 18243099, 19357306, 20638385, 20739936, 20826784, 21051298, 21225229, 21536684, 21988832, 23251006, 23825075, 24571573, 25778398, 27332895, 28218735, 28514442, 29568061, 322
GO:0005634	Component	Nucleus	IDA	15665297, 20627126, 20826784, 21364656
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	9256286, 16291752, 20627126, 21364656
GO:0005737	Component	Cytoplasm	IEA
GO:0005814	Component	Centriole	IDA	9859993
GO:0005819	Component	Spindle	IEA
GO:0005829	Component	Cytosol	IDA	12773388, 18591255
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0005876	Component	Spindle microtubule	IDA	9859993, 11069302
GO:0005881	Component	Cytoplasmic microtubule	IDA	9859993
GO:0006915	Process	Apoptotic process	IEA
GO:0007052	Process	Mitotic spindle organization	IBA
GO:0007059	Process	Chromosome segregation	IBA
GO:0007059	Process	Chromosome segregation	IEA
GO:0007094	Process	Mitotic spindle assembly checkpoint signaling	IMP	12805209
GO:0007605	Process	Sensory perception of sound	IEP	20627126
GO:0008017	Function	Microtubule binding	IDA	9859993
GO:0008017	Function	Microtubule binding	TAS	21536684
GO:0008270	Function	Zinc ion binding	IDA	10876248
GO:0008270	Function	Zinc ion binding	NAS	10949039
GO:0008284	Process	Positive regulation of cell population proliferation	TAS	16344111
GO:0015630	Component	Microtubule cytoskeleton	IDA	9859993
GO:0015631	Function	Tubulin binding	IDA	9859993
GO:0019899	Function	Enzyme binding	IPI	16322459
GO:0030414	Function	Peptidase inhibitor activity	IEA
GO:0030496	Component	Midbody	IDA	9859993, 11069302, 11084331, 15665297, 16291752
GO:0030496	Component	Midbody	IEA
GO:0031021	Component	Interphase microtubule organizing center	IDA	9859993
GO:0031267	Function	Small GTPase binding	IPI	18591255
GO:0031503	Process	Protein-containing complex localization	IMP	16239925
GO:0031536	Process	Positive regulation of exit from mitosis	IMP	12805209
GO:0032133	Component	Chromosome passenger complex	IBA
GO:0032133	Component	Chromosome passenger complex	IPI	15260989, 17956729, 18591255
GO:0032991	Component	Protein-containing complex	IDA	12773388
GO:0042802	Function	Identical protein binding	IPI	16291752, 17099693, 23251006
GO:0042803	Function	Protein homodimerization activity	IDA	10876248, 10949039
GO:0042803	Function	Protein homodimerization activity	IPI	16291752
GO:0043027	Function	Cysteine-type endopeptidase inhibitor activity involved in apoptotic process	IMP	9859993
GO:0043066	Process	Negative regulation of apoptotic process	IBA
GO:0043066	Process	Negative regulation of apoptotic process	IDA	9256286, 9859993, 10626797, 10949038, 12773388, 20627126, 21364656
GO:0043066	Process	Negative regulation of apoptotic process	IEA
GO:0043066	Process	Negative regulation of apoptotic process	IMP	21536684, 25778398, 28218735
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	20826784
GO:0045931	Process	Positive regulation of mitotic cell cycle	IMP	16291752
GO:0046872	Function	Metal ion binding	IEA
GO:0046982	Function	Protein heterodimerization activity	IDA	16291752
GO:0050000	Process	Chromosome localization	IMP	12805209
GO:0050897	Function	Cobalt ion binding	NAS	10949039
GO:0051087	Function	Protein-folding chaperone binding	IPI	18086682
GO:0051233	Component	Spindle midzone	IBA
GO:0051256	Process	Mitotic spindle midzone assembly	NAS	17956729
GO:0051301	Process	Cell division	IEA
GO:0051301	Process	Cell division	IMP	12805209
GO:0090267	Process	Positive regulation of mitotic cell cycle spindle assembly checkpoint	NAS	17956729
GO:0090307	Process	Mitotic spindle assembly	NAS	17956729
GO:1901970	Process	Positive regulation of mitotic sister chromatid separation	NAS	17956729
GO:1902425	Process	Positive regulation of attachment of mitotic spindle microtubules to kinetochore	NAS	17956729
GO:1903490	Process	Positive regulation of mitotic cytokinesis	NAS	17956729
GO:1990713	Component	Survivin complex	IPI	10949038

MIM	HGNC	e!Ensembl
603352	593	ENSG00000089685

O15392

Protein name

Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)

Protein function

Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:20627126, PubMed:21364656, PubMed:25778398, PubMed:28218735, PubMed:9859993). Component of a chromosome passage protein complex (CPC) which

PDB

1E31 , 1F3H , 1XOX , 2QFA , 2RAW , 2RAX , 3UEC , 3UED , 3UEE , 3UEF , 3UEG , 3UEH , 3UEI , 3UIG , 3UIH , 3UII , 3UIJ , 3UIK , 4A0I , 4A0J , 4A0N , 6SHO , 6YIE , 6YIF , 6YIH , 7LBK , 7LBO , 7LBP , 7LBQ , 8RUP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00653	BIR	18 → 88	Inhibitor of Apoptosis domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed only in fetal kidney and liver, and to lesser extent, lung and brain (PubMed:10626797). Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas (PubMed:14741722, PubMed

Sequence

MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFC
FKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNK
KKEFEETAKKVRRAIEQLAAMD

Sequence length

142

Interactions

View interactions

	KEGG		Reactome
	Platinum drug resistance Apoptosis Apoptosis - multiple species Hippo signaling pathway Hepatitis B Pathways in cancer Chemical carcinogenesis - receptor activation Colorectal cancer		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Mitotic Prometaphase Neddylation EML4 and NUDC in mitotic spindle formation

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	rs756245585, rs146071276	RCV004557930 RCV004557940

Show/Hide Text Mining Associations (111)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Acute Disease	Associate	35685607
Adenocarcinoma	Stimulate	31093306
Adenocarcinoma	Associate	32998713
Adenocarcinoma Mucinous	Associate	33451982
Adenocarcinoma of Lung	Associate	23874428, 31093306, 31698633, 35029906, 37741993, 38017020, 38216925
Adenocarcinoma of Lung	Stimulate	33398330
Adenoma	Associate	24472434
Adenomatous Polyposis Coli	Associate	24472434
Adrenocortical Carcinoma	Associate	37895143, 38053725
Anemia Aplastic	Inhibit	33586472
Angina Stable	Stimulate	26537080
Arthritis Rheumatoid	Associate	24959711, 38302188
Astrocytoma	Associate	36115056
Azoospermia	Associate	35219767
Breast Neoplasms	Associate	17591932, 21707964, 25586992, 27372966, 28187446, 29330624, 31895772, 32043523, 32649310, 32841536, 35053185, 35456460, 36100919, 37713876, 40725442
Carcinogenesis	Associate	32043523, 33888009
Carcinoid Tumor	Associate	23929435
Carcinoma Hepatocellular	Associate	19140237, 22214342, 32815653, 33457419, 33540684, 33778066, 34112092, 34691238, 34746309, 34840632, 35030478, 36032071, 36292719, 36345011, 36353638, 37248280, 37679418, 39985496 View all (3 more)
Carcinoma Intraductal Noninfiltrating	Associate	35880695
Carcinoma Non Small Cell Lung	Associate	20881643, 25677909, 31746439, 32299382, 35132928, 35326407
Carcinoma Pancreatic Ductal	Associate	20808857, 34671679
Carcinoma Renal Cell	Associate	22295057, 26061684, 31422942, 31626592, 32662515, 32986937, 33761648, 33858375, 34265766, 35896362, 36793506
Carcinoma Renal Cell	Stimulate	38203388
Carcinoma Squamous Cell	Associate	28949095, 32468587, 33477943, 33888009, 37442189
Carcinoma Squamous Cell	Stimulate	35331169
Cell Transformation Neoplastic	Stimulate	29328367
Cerebral Infarction	Associate	35685607
Cholangiocarcinoma	Associate	33725402
Colorectal Neoplasms	Associate	24240588, 25374237, 27827395, 29516317, 30415515
Colorectal Neoplasms	Stimulate	34797333
Constriction Pathologic	Stimulate	27399126
Disease	Associate	38139318
Disease Progression	Stimulate	26537080
Dissection Thoracic Aorta	Associate	31380418
Endometrial Neoplasms	Associate	20798131, 33109128
Epstein Barr Virus Infections	Associate	33451982
Esophageal Neoplasms	Associate	20236666
Esophageal Squamous Cell Carcinoma	Stimulate	34517565
Esophageal Squamous Cell Carcinoma	Associate	37312528
Gallbladder Neoplasms	Associate	25970782
Gastrointestinal Neoplasms	Associate	34484469
Gastrointestinal Stromal Tumors	Associate	27167336, 29277888
Glioblastoma	Associate	27409668
Glioma	Stimulate	37806253
Hallucinations	Associate	32710539
Heart Valve Diseases	Associate	33518654
HIV Infections	Associate	33931637
Homozygous Familial Hypercholesterolemia	Stimulate	34052320
Infarction Anterior Cerebral Artery	Associate	35685607
Inflammation	Associate	26474386
Intervertebral Disc Degeneration	Associate	36175893
Keratosis Actinic	Associate	33888854
Leukemia	Stimulate	19131553
Leukemia	Associate	21844871, 31104397
Leukemia Lymphocytic Chronic B Cell	Associate	16763612
Leukemia Lymphoma Adult T Cell	Associate	19131553
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	34053416
Leukemia Myeloid Acute	Associate	24127439, 31104397, 36248870
Lung Diseases Interstitial	Stimulate	38302188
Lung Neoplasms	Associate	26647102, 35178291
Lung Neoplasms	Stimulate	37806253
Lymphatic Metastasis	Associate	19140237, 25970782, 37312528, 40725442
Lymphoma T Cell Cutaneous	Associate	31358475, 35787399
Medulloblastoma	Associate	30991098
Melanoma	Associate	16116595, 17611626, 33046735, 37435067
Melanoma	Stimulate	17916908
Melanoma Cutaneous Malignant	Associate	34087900
Meningioma	Associate	21157382
Mouth Neoplasms	Associate	26474386, 30205554, 35421271
Multiple Myeloma	Associate	26537080, 31638931
Multiple Sclerosis	Associate	31438837
Nasopharyngeal Carcinoma	Associate	18570662, 21304814, 32572938, 35509856, 37647439
Necrosis	Inhibit	31104397
Neoplasm Metastasis	Associate	17916908, 23874428, 31093306, 32043523, 34154613
Neoplasms	Associate	16892011, 17591932, 17916908, 18522746, 18535745, 19470765, 21304814, 21844871, 21948653, 22295057, 23883402, 24037645, 25148540, 26474386, 27144529 View all (33 more)
Neoplasms	Inhibit	18570662, 29767242
Neoplasms	Stimulate	34728699, 35178302
Neoplasms Squamous Cell	Associate	19120021
Neuroblastoma	Associate	22088485, 28467792
Neurofibrosarcoma	Associate	15255999, 18522746, 24303016
Obesity	Associate	29330624
Obstetric Labor Premature	Associate	36768802
Osteochondritis	Associate	31758856
Osteosarcoma	Associate	30402837, 32945459, 33153400, 40616392
Ovarian Diseases	Associate	23029477
Ovarian Diseases	Stimulate	35331169
Ovarian Neoplasms	Associate	22277193, 27323861, 28326515, 30736319, 31177266, 31987036
Pancreatic Neoplasms	Associate	26125713, 29764514
Pancreatitis	Associate	26125713
Penile Neoplasms	Associate	28751665
Peripheral Nervous System Neoplasms	Associate	25769404
Personality Disorders	Associate	21157382, 30991098
Polycystic Ovary Syndrome	Stimulate	39381438
Pre Eclampsia	Associate	21075447
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	34638823
Prostatic Hyperplasia	Associate	37426635
Prostatic Neoplasms	Associate	23883402, 27144529, 32264916, 32664150, 34806485
Prostatic Neoplasms	Stimulate	32094363
Pulmonary Fibrosis	Associate	38302188
Rhabdoid Tumor	Associate	36572559
Sertoli Cell Only Syndrome	Associate	35833143
Squamous Cell Carcinoma of Head and Neck	Associate	30205554, 33892811, 34198450, 35178302, 37408277, 37547764, 38139318
Stomach Neoplasms	Associate	27384994, 32902196, 33451982
Tarlov Cysts	Associate	24240588
Thyroid Carcinoma Anaplastic	Associate	31183379
Thyroid Nodule	Associate	24945990
Tissue Adhesions	Associate	34968168
Triple Negative Breast Neoplasms	Associate	22713668, 31093306, 32766313, 33297339, 35631261
Urinary Bladder Neoplasms	Associate	16892011, 24520312, 28139689, 39892702
Uterine Cervical Neoplasms	Associate	29767242, 31337953, 38555994
Vascular Diseases	Associate	35685607

BIRC5 (baculoviral IAP repeat containing 5)