Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	3268
Gene name Gene Name - the full gene name approved by the HGNC.	ArfGAP with FG repeats 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	AGFG2
Synonyms (NCBI Gene) Gene synonyms aliases	HRBL, RABR
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and play

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018284	hsa-miR-335-5p	Microarray	18185580
MIRT052062	hsa-let-7b-5p	CLASH	23622248
MIRT042987	hsa-miR-324-3p	CLASH	23622248
MIRT169669	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT169663	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT169669	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT169662	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT169682	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT169664	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT169693	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT169663	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT771869	hsa-miR-106a	CLIP-seq
MIRT771870	hsa-miR-106b	CLIP-seq
MIRT771871	hsa-miR-1225-3p	CLIP-seq
MIRT771872	hsa-miR-1226	CLIP-seq
MIRT771873	hsa-miR-1231	CLIP-seq
MIRT771874	hsa-miR-1233	CLIP-seq
MIRT771875	hsa-miR-1237	CLIP-seq
MIRT771876	hsa-miR-1245b-5p	CLIP-seq
MIRT771877	hsa-miR-1254	CLIP-seq
MIRT771878	hsa-miR-125a-3p	CLIP-seq
MIRT771879	hsa-miR-1262	CLIP-seq
MIRT771880	hsa-miR-1266	CLIP-seq
MIRT771881	hsa-miR-1273e	CLIP-seq
MIRT771882	hsa-miR-1321	CLIP-seq
MIRT771883	hsa-miR-1343	CLIP-seq
MIRT771884	hsa-miR-136	CLIP-seq
MIRT771885	hsa-miR-141	CLIP-seq
MIRT771886	hsa-miR-1537	CLIP-seq
MIRT771887	hsa-miR-1538	CLIP-seq
MIRT771888	hsa-miR-17	CLIP-seq
MIRT771889	hsa-miR-193a-5p	CLIP-seq
MIRT771890	hsa-miR-200a	CLIP-seq
MIRT771891	hsa-miR-20a	CLIP-seq
MIRT771892	hsa-miR-20b	CLIP-seq
MIRT771893	hsa-miR-2278	CLIP-seq
MIRT771894	hsa-miR-2861	CLIP-seq
MIRT771895	hsa-miR-297	CLIP-seq
MIRT771896	hsa-miR-302a	CLIP-seq
MIRT771897	hsa-miR-302b	CLIP-seq
MIRT771898	hsa-miR-302c	CLIP-seq
MIRT771899	hsa-miR-302d	CLIP-seq
MIRT771900	hsa-miR-302e	CLIP-seq
MIRT771901	hsa-miR-3074-5p	CLIP-seq
MIRT771902	hsa-miR-3116	CLIP-seq
MIRT771903	hsa-miR-3120-5p	CLIP-seq
MIRT771904	hsa-miR-3129-3p	CLIP-seq
MIRT771905	hsa-miR-3142	CLIP-seq
MIRT771906	hsa-miR-3163	CLIP-seq
MIRT771907	hsa-miR-3169	CLIP-seq
MIRT771908	hsa-miR-3176	CLIP-seq
MIRT771909	hsa-miR-3184	CLIP-seq
MIRT771910	hsa-miR-3192	CLIP-seq
MIRT771911	hsa-miR-3200-5p	CLIP-seq
MIRT771912	hsa-miR-3545-5p	CLIP-seq
MIRT771913	hsa-miR-3609	CLIP-seq
MIRT771914	hsa-miR-3614-5p	CLIP-seq
MIRT771915	hsa-miR-3622a-3p	CLIP-seq
MIRT771916	hsa-miR-3622b-3p	CLIP-seq
MIRT771917	hsa-miR-3650	CLIP-seq
MIRT771918	hsa-miR-3663-5p	CLIP-seq
MIRT771919	hsa-miR-3664-3p	CLIP-seq
MIRT771920	hsa-miR-3714	CLIP-seq
MIRT771921	hsa-miR-372	CLIP-seq
MIRT771922	hsa-miR-373	CLIP-seq
MIRT771923	hsa-miR-378g	CLIP-seq
MIRT771924	hsa-miR-3922-3p	CLIP-seq
MIRT771925	hsa-miR-3924	CLIP-seq
MIRT771926	hsa-miR-3978	CLIP-seq
MIRT771927	hsa-miR-423-5p	CLIP-seq
MIRT771928	hsa-miR-425	CLIP-seq
MIRT771929	hsa-miR-4300	CLIP-seq
MIRT771930	hsa-miR-4314	CLIP-seq
MIRT771931	hsa-miR-4436a	CLIP-seq
MIRT771932	hsa-miR-4455	CLIP-seq
MIRT771933	hsa-miR-4505	CLIP-seq
MIRT771934	hsa-miR-4518	CLIP-seq
MIRT771935	hsa-miR-455-5p	CLIP-seq
MIRT771936	hsa-miR-4640-5p	CLIP-seq
MIRT771937	hsa-miR-4643	CLIP-seq
MIRT771938	hsa-miR-4646-5p	CLIP-seq
MIRT771939	hsa-miR-4649-3p	CLIP-seq
MIRT771940	hsa-miR-4650-5p	CLIP-seq
MIRT771941	hsa-miR-4683	CLIP-seq
MIRT771942	hsa-miR-4701-3p	CLIP-seq
MIRT771943	hsa-miR-4717-3p	CLIP-seq
MIRT771944	hsa-miR-4722-3p	CLIP-seq
MIRT771945	hsa-miR-4726-3p	CLIP-seq
MIRT771946	hsa-miR-4726-5p	CLIP-seq
MIRT771947	hsa-miR-4728-5p	CLIP-seq
MIRT771948	hsa-miR-4733-3p	CLIP-seq
MIRT771949	hsa-miR-4739	CLIP-seq
MIRT771950	hsa-miR-4742-5p	CLIP-seq
MIRT771951	hsa-miR-4745-3p	CLIP-seq
MIRT771952	hsa-miR-4755-3p	CLIP-seq
MIRT771953	hsa-miR-4756-5p	CLIP-seq
MIRT771954	hsa-miR-4774-5p	CLIP-seq
MIRT771955	hsa-miR-4795-5p	CLIP-seq
MIRT771956	hsa-miR-4796-3p	CLIP-seq
MIRT771957	hsa-miR-483-3p	CLIP-seq
MIRT771958	hsa-miR-515-5p	CLIP-seq
MIRT771959	hsa-miR-516a-3p	CLIP-seq
MIRT771960	hsa-miR-519d	CLIP-seq
MIRT771961	hsa-miR-520a-3p	CLIP-seq
MIRT771962	hsa-miR-520b	CLIP-seq
MIRT771963	hsa-miR-520c-3p	CLIP-seq
MIRT771964	hsa-miR-520d-3p	CLIP-seq
MIRT771965	hsa-miR-520e	CLIP-seq
MIRT771966	hsa-miR-520f	CLIP-seq
MIRT771967	hsa-miR-548ah	CLIP-seq
MIRT771968	hsa-miR-548an	CLIP-seq
MIRT771969	hsa-miR-555	CLIP-seq
MIRT771970	hsa-miR-567	CLIP-seq
MIRT771971	hsa-miR-609	CLIP-seq
MIRT771972	hsa-miR-635	CLIP-seq
MIRT771973	hsa-miR-636	CLIP-seq
MIRT771974	hsa-miR-642b	CLIP-seq
MIRT771975	hsa-miR-661	CLIP-seq
MIRT771976	hsa-miR-920	CLIP-seq
MIRT771977	hsa-miR-93	CLIP-seq
MIRT771978	hsa-miR-940	CLIP-seq
MIRT771878	hsa-miR-125a-3p	CLIP-seq
MIRT771882	hsa-miR-1321	CLIP-seq
MIRT771883	hsa-miR-1343	CLIP-seq
MIRT771884	hsa-miR-136	CLIP-seq
MIRT771886	hsa-miR-1537	CLIP-seq
MIRT771887	hsa-miR-1538	CLIP-seq
MIRT1927775	hsa-miR-182	CLIP-seq
MIRT1927776	hsa-miR-1915	CLIP-seq
MIRT1927777	hsa-miR-2110	CLIP-seq
MIRT1927778	hsa-miR-2355-5p	CLIP-seq
MIRT1927779	hsa-miR-2467-3p	CLIP-seq
MIRT1927780	hsa-miR-3135b	CLIP-seq
MIRT1927781	hsa-miR-3148	CLIP-seq
MIRT1927782	hsa-miR-3178	CLIP-seq
MIRT1927783	hsa-miR-3652	CLIP-seq
MIRT1927784	hsa-miR-4271	CLIP-seq
MIRT1927785	hsa-miR-4284	CLIP-seq
MIRT1927786	hsa-miR-4312	CLIP-seq
MIRT1927787	hsa-miR-4419a	CLIP-seq
MIRT1927788	hsa-miR-4423-5p	CLIP-seq
MIRT1927789	hsa-miR-4430	CLIP-seq
MIRT771931	hsa-miR-4436a	CLIP-seq
MIRT1927790	hsa-miR-4446-3p	CLIP-seq
MIRT1927791	hsa-miR-4486	CLIP-seq
MIRT1927792	hsa-miR-4492	CLIP-seq
MIRT1927793	hsa-miR-4498	CLIP-seq
MIRT1927794	hsa-miR-4510	CLIP-seq
MIRT1927795	hsa-miR-4530	CLIP-seq
MIRT771940	hsa-miR-4650-5p	CLIP-seq
MIRT1927796	hsa-miR-4667-5p	CLIP-seq
MIRT1927797	hsa-miR-4700-5p	CLIP-seq
MIRT771943	hsa-miR-4717-3p	CLIP-seq
MIRT1927798	hsa-miR-4721	CLIP-seq
MIRT1927799	hsa-miR-4725-3p	CLIP-seq
MIRT1927800	hsa-miR-4731-5p	CLIP-seq
MIRT771949	hsa-miR-4739	CLIP-seq
MIRT771951	hsa-miR-4745-3p	CLIP-seq
MIRT771953	hsa-miR-4756-5p	CLIP-seq
MIRT1927801	hsa-miR-4793-5p	CLIP-seq
MIRT1927802	hsa-miR-548p	CLIP-seq
MIRT1927803	hsa-miR-552	CLIP-seq
MIRT771969	hsa-miR-555	CLIP-seq
MIRT1927804	hsa-miR-603	CLIP-seq
MIRT1927805	hsa-miR-762	CLIP-seq
MIRT771869	hsa-miR-106a	CLIP-seq
MIRT771870	hsa-miR-106b	CLIP-seq
MIRT2168680	hsa-miR-1207-5p	CLIP-seq
MIRT771877	hsa-miR-1254	CLIP-seq
MIRT771881	hsa-miR-1273e	CLIP-seq
MIRT2168681	hsa-miR-1293	CLIP-seq
MIRT771883	hsa-miR-1343	CLIP-seq
MIRT771886	hsa-miR-1537	CLIP-seq
MIRT771887	hsa-miR-1538	CLIP-seq
MIRT771888	hsa-miR-17	CLIP-seq
MIRT771891	hsa-miR-20a	CLIP-seq
MIRT771892	hsa-miR-20b	CLIP-seq
MIRT771893	hsa-miR-2278	CLIP-seq
MIRT771896	hsa-miR-302a	CLIP-seq
MIRT771897	hsa-miR-302b	CLIP-seq
MIRT771898	hsa-miR-302c	CLIP-seq
MIRT771899	hsa-miR-302d	CLIP-seq
MIRT771900	hsa-miR-302e	CLIP-seq
MIRT771901	hsa-miR-3074-5p	CLIP-seq
MIRT771902	hsa-miR-3116	CLIP-seq
MIRT771904	hsa-miR-3129-3p	CLIP-seq
MIRT2168682	hsa-miR-3183	CLIP-seq
MIRT771910	hsa-miR-3192	CLIP-seq
MIRT771913	hsa-miR-3609	CLIP-seq
MIRT771917	hsa-miR-3650	CLIP-seq
MIRT2168683	hsa-miR-3661	CLIP-seq
MIRT771920	hsa-miR-3714	CLIP-seq
MIRT771921	hsa-miR-372	CLIP-seq
MIRT771922	hsa-miR-373	CLIP-seq
MIRT771923	hsa-miR-378g	CLIP-seq
MIRT771925	hsa-miR-3924	CLIP-seq
MIRT2168684	hsa-miR-3929	CLIP-seq
MIRT2168685	hsa-miR-4274	CLIP-seq
MIRT771929	hsa-miR-4300	CLIP-seq
MIRT771930	hsa-miR-4314	CLIP-seq
MIRT2168686	hsa-miR-4419b	CLIP-seq
MIRT2168687	hsa-miR-4434	CLIP-seq
MIRT2168688	hsa-miR-4447	CLIP-seq
MIRT771932	hsa-miR-4455	CLIP-seq
MIRT2168689	hsa-miR-4472	CLIP-seq
MIRT2168690	hsa-miR-4478	CLIP-seq
MIRT2168691	hsa-miR-4483	CLIP-seq
MIRT771933	hsa-miR-4505	CLIP-seq
MIRT2168692	hsa-miR-4516	CLIP-seq
MIRT1927795	hsa-miR-4530	CLIP-seq
MIRT771937	hsa-miR-4643	CLIP-seq
MIRT771938	hsa-miR-4646-5p	CLIP-seq
MIRT771941	hsa-miR-4683	CLIP-seq
MIRT2168693	hsa-miR-4690-3p	CLIP-seq
MIRT771943	hsa-miR-4717-3p	CLIP-seq
MIRT771944	hsa-miR-4722-3p	CLIP-seq
MIRT2168694	hsa-miR-4723-3p	CLIP-seq
MIRT771951	hsa-miR-4745-3p	CLIP-seq
MIRT2168695	hsa-miR-4763-3p	CLIP-seq
MIRT771956	hsa-miR-4796-3p	CLIP-seq
MIRT771957	hsa-miR-483-3p	CLIP-seq
MIRT2168696	hsa-miR-485-5p	CLIP-seq
MIRT771959	hsa-miR-516a-3p	CLIP-seq
MIRT771960	hsa-miR-519d	CLIP-seq
MIRT771961	hsa-miR-520a-3p	CLIP-seq
MIRT771962	hsa-miR-520b	CLIP-seq
MIRT771963	hsa-miR-520c-3p	CLIP-seq
MIRT771964	hsa-miR-520d-3p	CLIP-seq
MIRT771965	hsa-miR-520e	CLIP-seq
MIRT771966	hsa-miR-520f	CLIP-seq
MIRT771967	hsa-miR-548ah	CLIP-seq
MIRT2168697	hsa-miR-550b	CLIP-seq
MIRT771969	hsa-miR-555	CLIP-seq
MIRT771971	hsa-miR-609	CLIP-seq
MIRT2168698	hsa-miR-622	CLIP-seq
MIRT2168699	hsa-miR-631	CLIP-seq
MIRT771973	hsa-miR-636	CLIP-seq
MIRT771975	hsa-miR-661	CLIP-seq
MIRT771976	hsa-miR-920	CLIP-seq
MIRT771977	hsa-miR-93	CLIP-seq
MIRT771978	hsa-miR-940	CLIP-seq
MIRT1927800	hsa-miR-4731-5p	CLIP-seq
MIRT2168697	hsa-miR-550b	CLIP-seq
MIRT2383999	hsa-miR-625	CLIP-seq
MIRT771903	hsa-miR-3120-5p	CLIP-seq
MIRT2443333	hsa-miR-4640-3p	CLIP-seq
MIRT2443334	hsa-miR-4732-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005096	Function	GTPase activator activity	IEA
GO:0008150	Process	Biological_process	ND
GO:0016020	Component	Membrane	HDA	19946888
GO:0043547	Process	Positive regulation of GTPase activity	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
604019	5177	ENSG00000106351

Protein

UniProt ID

O95081

Protein name

Arf-GAP domain and FG repeat-containing protein 2 (HIV-1 Rev-binding protein-like protein) (Rev/Rex activation domain-binding protein related) (RAB-R)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01412	ArfGap	32 → 148	Putative GTPase activating protein for Arf	Domain

Sequence

MVMAAKKGPGPGGGVSGGKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDI
TVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVVFLQSRGNEVCRKIWLGLFDARTS
LVPDSRDPQKVKEFLQEKYEKKRWYVPPDQVKGPTYTKGSASTPVQGSIPEGKPLRTLLG
DPAPSLSVAASTSSQPVSQSHARTSQARSTQPPPHSSVKKASTDLLADIGGDPFAAPQMA
PAFAAFPAFGGQTPSQGGFANFDAFSSGPSSSVFGSLPPAGQASFQAQPTPAGSSQGTPF
GATPLAPASQPNSLADVGSFLGPGVPAAGVPSSLFGMAGQVPPLQSVTMGGGGGSSTGLA
FGAFTNPFTAPAAQSPLPSTNPFQPNGLAPGPGFGMSSAGPGFPQAVPPTGAFASSFPAP
LFPPQTPLVQQQNGSSFGDLGSAKLGQRPLSQPAGISTNPFMTGPSSSPFASKPPTTNPF
L

Sequence length

481

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Alzheimer disease	Alzheimer`s Disease	rs63750215, rs28936379, rs63749851, rs63749884, rs28936380, rs63750048, rs63750579, rs63750264, rs63749964, rs63750671, rs281865161, rs63750066, rs63750399, rs63750734, rs63751039 View all (65 more)	29777097

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text Mining
Achalasia Addisonianism Alacrimia syndrome	Associate	37331934
Acute Febrile Encephalopathy	Associate	31178128
Anaplasia	Associate	30036517
Endometriosis	Associate	31256999
Familial Glucocorticoid Deficiency 1	Associate	37331934
Intellectual Disability	Associate	34494102
Leukemia Myeloid Acute	Associate	10908574, 9050861
Myelodysplastic Syndromes	Associate	10830185
Ovarian Neoplasms	Associate	22074739
Pena Shokeir syndrome type 1	Associate	33168876
Retinoblastoma	Associate	30036517

AGFG2 (ArfGAP with FG repeats 2)