APBB2 (amyloid beta precursor protein binding family B member 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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323 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Amyloid beta precursor protein binding family B member 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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APBB2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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FE65L, FE65L1 |
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Chromosome
Chromosome number
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4 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4p14-p13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function i |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q92870 | ||||||||||||||||||||
| Protein name | Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1) | ||||||||||||||||||||
| Protein function | Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (By similarity). Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory fu | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:8855266}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 758 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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