Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	3215
Gene name	Homeobox B5
Gene symbol	HOXB5
Synonyms (NCBI Gene)	HHO.C10HOX2HOX2AHU-1Hox2.1
Chromosome	17
Chromosome location	17q21.32
Summary	This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcriptio

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001971	hsa-miR-221-3p	Gluc assay	18794255
MIRT006902	hsa-miR-7-5p	ImmunohistochemistryLuciferase reporter assayqRT-PCRWestern blot	22768238
MIRT016641	hsa-miR-429	Reporter assay	20005803
MIRT020354	hsa-miR-200a-3p	Reporter assay	20005803
MIRT021075	hsa-miR-200c-3p	Reporter assay	20005803
MIRT021658	hsa-miR-141-3p	Reporter assay	20005803
MIRT024129	hsa-miR-200b-3p	Reporter assay	20005803
MIRT657301	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT657300	hsa-miR-1285-5p	HITS-CLIP	23824327
MIRT657299	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT657298	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT657297	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT657296	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT657295	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT657294	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT657293	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT657292	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT657291	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT657290	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT657289	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT657288	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT657287	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT657286	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT616105	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT616104	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616103	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT616102	hsa-miR-637	HITS-CLIP	23824327
MIRT616101	hsa-miR-625-5p	HITS-CLIP	23824327
MIRT616100	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616099	hsa-miR-5698	HITS-CLIP	23824327
MIRT616098	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616097	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616096	hsa-miR-4525	HITS-CLIP	23824327
MIRT616095	hsa-miR-5010-5p	HITS-CLIP	23824327
MIRT616094	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT616093	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT616092	hsa-miR-1275	HITS-CLIP	23824327
MIRT616091	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT616090	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT616089	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT616105	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT616104	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616103	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT616102	hsa-miR-637	HITS-CLIP	23824327
MIRT616101	hsa-miR-625-5p	HITS-CLIP	23824327
MIRT616100	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616099	hsa-miR-5698	HITS-CLIP	23824327
MIRT616098	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616097	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616096	hsa-miR-4525	HITS-CLIP	23824327
MIRT616095	hsa-miR-5010-5p	HITS-CLIP	23824327
MIRT616094	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT616093	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT616092	hsa-miR-1275	HITS-CLIP	23824327
MIRT616091	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT616090	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT616089	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT491458	hsa-miR-4779	PAR-CLIP	23592263
MIRT491457	hsa-miR-1321	PAR-CLIP	23592263
MIRT491456	hsa-miR-4739	PAR-CLIP	23592263
MIRT491454	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT491455	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT491453	hsa-miR-4784	PAR-CLIP	23592263
MIRT491452	hsa-miR-4419a	PAR-CLIP	23592263
MIRT491451	hsa-miR-4510	PAR-CLIP	23592263
MIRT491450	hsa-miR-6127	PAR-CLIP	23592263
MIRT491449	hsa-miR-6129	PAR-CLIP	23592263
MIRT491448	hsa-miR-6130	PAR-CLIP	23592263
MIRT491447	hsa-miR-6133	PAR-CLIP	23592263
MIRT491446	hsa-miR-765	PAR-CLIP	23592263
MIRT491445	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT491444	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT491443	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT491442	hsa-miR-4689	PAR-CLIP	23592263
MIRT491441	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT657301	hsa-miR-216a-5p	HITS-CLIP	23824327
MIRT657300	hsa-miR-1285-5p	HITS-CLIP	23824327
MIRT657299	hsa-miR-141-5p	HITS-CLIP	23824327
MIRT657298	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT657297	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT657296	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT657295	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT657294	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT657293	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT657292	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT657291	hsa-miR-513c-5p	HITS-CLIP	23824327
MIRT657290	hsa-miR-514b-5p	HITS-CLIP	23824327
MIRT657289	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT657288	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT657287	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT657286	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT616105	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT616104	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616103	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT616102	hsa-miR-637	HITS-CLIP	23824327
MIRT616101	hsa-miR-625-5p	HITS-CLIP	23824327
MIRT616100	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616099	hsa-miR-5698	HITS-CLIP	23824327
MIRT616098	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616097	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616096	hsa-miR-4525	HITS-CLIP	23824327
MIRT616095	hsa-miR-5010-5p	HITS-CLIP	23824327
MIRT616094	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT616093	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT616092	hsa-miR-1275	HITS-CLIP	23824327
MIRT616091	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT616090	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT616089	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT616105	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT616104	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT616103	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT616102	hsa-miR-637	HITS-CLIP	23824327
MIRT616101	hsa-miR-625-5p	HITS-CLIP	23824327
MIRT616100	hsa-miR-4723-5p	HITS-CLIP	23824327
MIRT616099	hsa-miR-5698	HITS-CLIP	23824327
MIRT616098	hsa-miR-6870-5p	HITS-CLIP	23824327
MIRT616097	hsa-miR-7111-5p	HITS-CLIP	23824327
MIRT616096	hsa-miR-4525	HITS-CLIP	23824327
MIRT616095	hsa-miR-5010-5p	HITS-CLIP	23824327
MIRT616094	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT616093	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT616092	hsa-miR-1275	HITS-CLIP	23824327
MIRT616091	hsa-miR-4665-5p	HITS-CLIP	23824327
MIRT616090	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT616089	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT491458	hsa-miR-4779	PAR-CLIP	23592263
MIRT491457	hsa-miR-1321	PAR-CLIP	23592263
MIRT491456	hsa-miR-4739	PAR-CLIP	23592263
MIRT491454	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT491455	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT491453	hsa-miR-4784	PAR-CLIP	23592263
MIRT491452	hsa-miR-4419a	PAR-CLIP	23592263
MIRT491451	hsa-miR-4510	PAR-CLIP	23592263
MIRT491450	hsa-miR-6127	PAR-CLIP	23592263
MIRT491449	hsa-miR-6129	PAR-CLIP	23592263
MIRT491448	hsa-miR-6130	PAR-CLIP	23592263
MIRT491447	hsa-miR-6133	PAR-CLIP	23592263
MIRT491446	hsa-miR-765	PAR-CLIP	23592263
MIRT491445	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT491444	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT491443	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT491442	hsa-miR-4689	PAR-CLIP	23592263
MIRT491441	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT1053358	hsa-miR-1343	CLIP-seq
MIRT1053359	hsa-miR-141	CLIP-seq
MIRT1053360	hsa-miR-181a	CLIP-seq
MIRT1053361	hsa-miR-181b	CLIP-seq
MIRT1053362	hsa-miR-181c	CLIP-seq
MIRT1053363	hsa-miR-181d	CLIP-seq
MIRT1053364	hsa-miR-200a	CLIP-seq
MIRT1053365	hsa-miR-3153	CLIP-seq
MIRT1053366	hsa-miR-4262	CLIP-seq
MIRT1053367	hsa-miR-4730	CLIP-seq
MIRT1053368	hsa-miR-543	CLIP-seq
MIRT1053369	hsa-miR-625	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0001650	Component	Fibrillar center	IDA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 28514442, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0009653	Process	Anatomical structure morphogenesis	TAS	3000607
GO:0009952	Process	Anterior/posterior pattern specification	IBA
GO:0009952	Process	Anterior/posterior pattern specification	IEA
GO:0045446	Process	Endothelial cell differentiation	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0048704	Process	Embryonic skeletal system morphogenesis	IEA
GO:0048706	Process	Embryonic skeletal system development	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
142960	5116	ENSG00000120075

P09067

Protein name

Homeobox protein Hox-B5 (Homeobox protein HHO.C10) (Homeobox protein Hox-2A) (Homeobox protein Hu-1)

Protein function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	195 → 251	Homeodomain	Domain

Tissue specificity

TISSUE SPECIFICITY: Spinal cord.

Sequence

MSSYFVNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSS
ASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCTNGDSHGAKPSASSPSDQ
ATSASSSANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWM
RKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKI
WFQNRRMKWKKDNKLKSMSLATAGSAFQP

Sequence length

269

Interactions

View interactions

HOXB5 (homeobox B5)