Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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3131
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Gene name
Gene Name - the full gene name approved by the HGNC.
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HLF transcription factor, PAR bZIP family member |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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HLF |
Synonyms (NCBI Gene)
Gene synonyms aliases
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- |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q22 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Burkitt`s lymphoma |
Burkitt Lymphoma |
rs28933407, rs121918683, rs121918684 |
20519628 |
Lymphoblastic leukemia |
Childhood Acute Lymphoblastic Leukemia, L2 Acute Lymphoblastic Leukemia, Precursor B-cell lymphoblastic leukemia, Precursor B-cell acute lymphoblastic leukemia, Precursor Cell Lymphoblastic Leukemia Lymphoma |
rs387906351, rs104894562, rs398122513, rs398122840, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699, rs1597567692, rs1597567985, rs1438890364, rs1288977950, rs1597552140, rs1597566356, rs1597566726, rs1597568117, rs2069719445, rs2069729948, rs2070018439, rs745708044, rs1169577591 View all (13 more) |
26214592, 20519628 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Mental depression |
Unipolar Depression, Major Depressive Disorder |
|
25880836 |
ClinVar |
Bipolar Disorder |
Bipolar Disorder |
|
|
GWAS |
Gout |
Gout |
|
|
GWAS |
Heart Failure |
Heart Failure |
|
|
GWAS |
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Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Adenocarcinoma of Lung |
Associate
|
33612479, 33979320, 35205284, 40124619 |
Breast Neoplasms |
Associate
|
39201344 |
Carcinoma Hepatocellular |
Associate
|
23991075 |
Carcinoma Renal Cell |
Associate
|
33099483 |
Chromosome 17 trisomy |
Associate
|
1516826 |
Chromosome Disorders |
Associate
|
32245383 |
Colorectal Neoplasms |
Associate
|
28402947 |
Glioma |
Inhibit
|
33578515 |
Inflammation |
Inhibit
|
37868991 |
Leukemia |
Associate
|
17379095, 31735627, 8639829 |
Leukemia Myeloid |
Associate
|
17379095 |
Leukemia Myeloid Acute |
Associate
|
34876631 |
Lung Neoplasms |
Associate
|
30867848, 34925645, 40124619 |
Neoplasm Metastasis |
Associate
|
37709768 |
Neoplasms |
Associate
|
33578515, 36155774, 37709768, 40076649 |
Neoplasms |
Inhibit
|
33612479 |
Neoplasms Adipose Tissue |
Associate
|
24571258 |
Obesity |
Associate
|
24571258 |
Ovarian Neoplasms |
Associate
|
37709768 |
Parkinson Disease |
Associate
|
23284986 |
Precursor B Cell Lymphoblastic Leukemia Lymphoma |
Associate
|
30487223 |
Precursor Cell Lymphoblastic Leukemia Lymphoma |
Associate
|
1516826, 31735627, 8065331, 8180393 |
Precursor T Cell Lymphoblastic Leukemia Lymphoma |
Associate
|
32245383 |
Squamous Cell Carcinoma of Head and Neck |
Associate
|
31109699, 31562292 |
|