OLA1 (Obg like ATPase 1)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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29789 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Obg like ATPase 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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OLA1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DOC45, GBP45, GTBP9, GTPBP9, PTD004 |
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Chromosome
Chromosome number
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2 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q31.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the GTPase protein family. The encoded protein interacts with breast cancer-associated gene 1 (BRCA1) and BRCA1-associated RING domain protein (BARD1), and is involved in centrosome regulation. Overexpression of this gene has |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9NTK5 | |||||||||||||||
| Protein name | Obg-like ATPase 1 (DNA damage-regulated overexpressed in cancer 45) (DOC45) (GTP-binding protein 9) | |||||||||||||||
| Protein function | Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. | |||||||||||||||
| PDB | 2OHF | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus. | |||||||||||||||
| Sequence |
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| Sequence length | 396 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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