Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
29070
Gene name Gene Name - the full gene name approved by the HGNC.
Cilia and flagella associated protein 263
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CFAP263
Synonyms (NCBI Gene) Gene synonyms aliases
CCDC113, HSPC065
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q21
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028268 hsa-miR-32-5p Sequencing 20371350
MIRT051698 hsa-let-7e-5p CLASH 23622248
MIRT038959 hsa-miR-22-5p CLASH 23622248
MIRT669198 hsa-miR-508-5p HITS-CLIP 23824327
MIRT242415 hsa-miR-25-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25074808, 32296183
GO:0005930 Component Axoneme IBA 21873635
GO:0032991 Component Protein-containing complex IDA 25074808
GO:0034451 Component Centriolar satellite IMP 25074808
GO:0036064 Component Ciliary basal body IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616070 25002 ENSG00000103021
Protein
UniProt ID Q9H0I3
Protein name Cilia- and flagella-associated protein 263
Protein function Component of centriolar satellites contributing to primary cilium formation (PubMed:25074808). In complex with CFAP263, acts as a regulator of ciliary beating that connects radial spoke 3 (RS3) to the inner dynein arm (IDA) and the nexin-dynein
PDB 8J07
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13870 DUF4201 178 354 Domain of unknown function (DUF4201) Coiled-coil
Sequence
MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQR
PPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRA
NAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNR
RRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARN
QELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRA
KAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKG
HRKAWN
RMKITNEQLQADYLAGK
Sequence length 377
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Unknown
Disease term Disease name Evidence References Source
Systemic lupus erythematosus Systemic lupus erythematosus GWAS
Biliary Cholangitis Biliary Cholangitis GWAS