Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	2887
Gene name Gene Name - the full gene name approved by the HGNC.	Growth factor receptor bound protein 10
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	GRB10
Synonyms (NCBI Gene) Gene synonyms aliases	GRB-IR, Grb-10, IRBP, MEG1, RSS
Disease Acronyms (UniProt) Disease acronyms from UniProt database	RSS
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7p12.1
Summary Summary of gene provided in NCBI Entrez Gene.	The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin re

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019136	hsa-miR-335-5p	Microarray	18185580
MIRT020299	hsa-miR-130b-3p	Sequencing	20371350
MIRT046714	hsa-miR-222-3p	CLASH	23622248
MIRT037307	hsa-miR-877-5p	CLASH	23622248
MIRT054627	hsa-miR-199b-5p	ChIP-seq, Flow, qRT-PCR, Western blot	24608802
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT513910	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT513909	hsa-miR-4295	PAR-CLIP	20371350
MIRT513908	hsa-miR-3666	PAR-CLIP	20371350
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT513904	hsa-miR-3609	PAR-CLIP	20371350
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT513901	hsa-miR-1245a	PAR-CLIP	20371350
MIRT513900	hsa-miR-8079	PAR-CLIP	20371350
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT557467	hsa-miR-570-3p	PAR-CLIP	20371350
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT513893	hsa-miR-504-3p	PAR-CLIP	20371350
MIRT513892	hsa-miR-548aw	PAR-CLIP	20371350
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT513910	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT513909	hsa-miR-4295	PAR-CLIP	20371350
MIRT513908	hsa-miR-3666	PAR-CLIP	20371350
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT513904	hsa-miR-3609	PAR-CLIP	20371350
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT513901	hsa-miR-1245a	PAR-CLIP	20371350
MIRT513900	hsa-miR-8079	PAR-CLIP	20371350
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT513893	hsa-miR-504-3p	PAR-CLIP	20371350
MIRT513892	hsa-miR-548aw	PAR-CLIP	20371350
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT513910	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT513909	hsa-miR-4295	PAR-CLIP	21572407
MIRT513908	hsa-miR-3666	PAR-CLIP	21572407
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT513904	hsa-miR-3609	PAR-CLIP	21572407
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	21572407
MIRT513901	hsa-miR-1245a	PAR-CLIP	21572407
MIRT513900	hsa-miR-8079	PAR-CLIP	21572407
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	21572407
MIRT557467	hsa-miR-570-3p	PAR-CLIP	21572407
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT513893	hsa-miR-504-3p	PAR-CLIP	21572407
MIRT513892	hsa-miR-548aw	PAR-CLIP	21572407
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	23446348
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	23446348
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	23446348
MIRT513910	hsa-miR-454-3p	PAR-CLIP	23446348
MIRT513909	hsa-miR-4295	PAR-CLIP	23446348
MIRT513908	hsa-miR-3666	PAR-CLIP	23446348
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	23446348
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT513904	hsa-miR-3609	PAR-CLIP	23446348
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	23446348
MIRT513901	hsa-miR-1245a	PAR-CLIP	23446348
MIRT513900	hsa-miR-8079	PAR-CLIP	23446348
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	23446348
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	23446348
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	23446348
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	23446348
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	23446348
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	23446348
MIRT513893	hsa-miR-504-3p	PAR-CLIP	23446348
MIRT513892	hsa-miR-548aw	PAR-CLIP	23446348
MIRT046714	hsa-miR-222-3p	Luciferase reporter assay	26236014
MIRT046714	hsa-miR-222-3p	Luciferase reporter assay	26236014
MIRT733050	hsa-miR-5195-3p	Luciferase reporter assay, Western blotting, qRT-PCR	33969901
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT513910	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT513909	hsa-miR-4295	PAR-CLIP	20371350
MIRT513908	hsa-miR-3666	PAR-CLIP	20371350
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT513904	hsa-miR-3609	PAR-CLIP	20371350
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT513901	hsa-miR-1245a	PAR-CLIP	20371350
MIRT513900	hsa-miR-8079	PAR-CLIP	20371350
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT557467	hsa-miR-570-3p	PAR-CLIP	20371350
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT513893	hsa-miR-504-3p	PAR-CLIP	20371350
MIRT513892	hsa-miR-548aw	PAR-CLIP	20371350
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	20371350
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	20371350
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	20371350
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	20371350
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	20371350
MIRT513910	hsa-miR-454-3p	PAR-CLIP	20371350
MIRT513909	hsa-miR-4295	PAR-CLIP	20371350
MIRT513908	hsa-miR-3666	PAR-CLIP	20371350
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	20371350
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	20371350
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	20371350
MIRT513904	hsa-miR-3609	PAR-CLIP	20371350
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	20371350
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	20371350
MIRT513901	hsa-miR-1245a	PAR-CLIP	20371350
MIRT513900	hsa-miR-8079	PAR-CLIP	20371350
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	20371350
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	20371350
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	20371350
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	20371350
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	20371350
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	20371350
MIRT513893	hsa-miR-504-3p	PAR-CLIP	20371350
MIRT513892	hsa-miR-548aw	PAR-CLIP	20371350
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT513910	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT513909	hsa-miR-4295	PAR-CLIP	21572407
MIRT513908	hsa-miR-3666	PAR-CLIP	21572407
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT513904	hsa-miR-3609	PAR-CLIP	21572407
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	21572407
MIRT513901	hsa-miR-1245a	PAR-CLIP	21572407
MIRT513900	hsa-miR-8079	PAR-CLIP	21572407
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	21572407
MIRT557467	hsa-miR-570-3p	PAR-CLIP	21572407
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT513893	hsa-miR-504-3p	PAR-CLIP	21572407
MIRT513892	hsa-miR-548aw	PAR-CLIP	21572407
MIRT513914	hsa-miR-19a-3p	PAR-CLIP	23446348
MIRT513913	hsa-miR-19b-3p	PAR-CLIP	23446348
MIRT513912	hsa-miR-130a-3p	PAR-CLIP	23446348
MIRT020299	hsa-miR-130b-3p	PAR-CLIP	23446348
MIRT513911	hsa-miR-301b-3p	PAR-CLIP	23446348
MIRT513910	hsa-miR-454-3p	PAR-CLIP	23446348
MIRT513909	hsa-miR-4295	PAR-CLIP	23446348
MIRT513908	hsa-miR-3666	PAR-CLIP	23446348
MIRT513907	hsa-miR-301a-3p	PAR-CLIP	23446348
MIRT513906	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT513905	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT513904	hsa-miR-3609	PAR-CLIP	23446348
MIRT513903	hsa-miR-548ah-5p	PAR-CLIP	23446348
MIRT513902	hsa-miR-4433b-3p	PAR-CLIP	23446348
MIRT513901	hsa-miR-1245a	PAR-CLIP	23446348
MIRT513900	hsa-miR-8079	PAR-CLIP	23446348
MIRT513899	hsa-miR-3613-3p	PAR-CLIP	23446348
MIRT513898	hsa-miR-548aj-5p	PAR-CLIP	23446348
MIRT513897	hsa-miR-548f-5p	PAR-CLIP	23446348
MIRT513896	hsa-miR-548g-5p	PAR-CLIP	23446348
MIRT513895	hsa-miR-548x-5p	PAR-CLIP	23446348
MIRT513894	hsa-miR-1468-3p	PAR-CLIP	23446348
MIRT513893	hsa-miR-504-3p	PAR-CLIP	23446348
MIRT513892	hsa-miR-548aw	PAR-CLIP	23446348
MIRT1032995	hsa-miR-105	CLIP-seq
MIRT1032996	hsa-miR-1203	CLIP-seq
MIRT1032997	hsa-miR-125a-5p	CLIP-seq
MIRT1032998	hsa-miR-125b	CLIP-seq
MIRT1032999	hsa-miR-1270	CLIP-seq
MIRT1033000	hsa-miR-127-5p	CLIP-seq
MIRT1033001	hsa-miR-1297	CLIP-seq
MIRT1033002	hsa-miR-1299	CLIP-seq
MIRT1033003	hsa-miR-1305	CLIP-seq
MIRT1033004	hsa-miR-1323	CLIP-seq
MIRT1033005	hsa-miR-141	CLIP-seq
MIRT1033006	hsa-miR-151-3p	CLIP-seq
MIRT1033007	hsa-miR-181a	CLIP-seq
MIRT1033008	hsa-miR-181b	CLIP-seq
MIRT1033009	hsa-miR-181c	CLIP-seq
MIRT1033010	hsa-miR-181d	CLIP-seq
MIRT1033011	hsa-miR-1827	CLIP-seq
MIRT1033012	hsa-miR-185	CLIP-seq
MIRT1033013	hsa-miR-1972	CLIP-seq
MIRT1033014	hsa-miR-1976	CLIP-seq
MIRT1033015	hsa-miR-200a	CLIP-seq
MIRT1033016	hsa-miR-2116	CLIP-seq
MIRT1033017	hsa-miR-26a	CLIP-seq
MIRT1033018	hsa-miR-26b	CLIP-seq
MIRT1033019	hsa-miR-300	CLIP-seq
MIRT1033020	hsa-miR-31	CLIP-seq
MIRT1033021	hsa-miR-3117-5p	CLIP-seq
MIRT1033022	hsa-miR-3127-3p	CLIP-seq
MIRT1033023	hsa-miR-3133	CLIP-seq
MIRT1033024	hsa-miR-3155	CLIP-seq
MIRT1033025	hsa-miR-3155b	CLIP-seq
MIRT1033026	hsa-miR-3160-3p	CLIP-seq
MIRT1033027	hsa-miR-3190	CLIP-seq
MIRT1033028	hsa-miR-3199	CLIP-seq
MIRT1033029	hsa-miR-3202	CLIP-seq
MIRT1033030	hsa-miR-345	CLIP-seq
MIRT1033031	hsa-miR-381	CLIP-seq
MIRT1033032	hsa-miR-3913-3p	CLIP-seq
MIRT1033033	hsa-miR-3929	CLIP-seq
MIRT1033034	hsa-miR-3944-5p	CLIP-seq
MIRT1033035	hsa-miR-409-3p	CLIP-seq
MIRT1033036	hsa-miR-421	CLIP-seq
MIRT1033037	hsa-miR-4262	CLIP-seq
MIRT1033038	hsa-miR-4263	CLIP-seq
MIRT1033039	hsa-miR-4275	CLIP-seq
MIRT1033040	hsa-miR-4306	CLIP-seq
MIRT1033041	hsa-miR-4319	CLIP-seq
MIRT1033042	hsa-miR-4325	CLIP-seq
MIRT1033043	hsa-miR-4328	CLIP-seq
MIRT1033044	hsa-miR-4419b	CLIP-seq
MIRT1033045	hsa-miR-4438	CLIP-seq
MIRT1033046	hsa-miR-4446-3p	CLIP-seq
MIRT1033047	hsa-miR-4463	CLIP-seq
MIRT1033048	hsa-miR-4465	CLIP-seq
MIRT1033049	hsa-miR-4478	CLIP-seq
MIRT1033050	hsa-miR-4487	CLIP-seq
MIRT1033051	hsa-miR-4499	CLIP-seq
MIRT1033052	hsa-miR-4504	CLIP-seq
MIRT1033053	hsa-miR-4513	CLIP-seq
MIRT1033054	hsa-miR-4515	CLIP-seq
MIRT1033055	hsa-miR-4531	CLIP-seq
MIRT1033056	hsa-miR-4644	CLIP-seq
MIRT1033057	hsa-miR-4646-5p	CLIP-seq
MIRT1033058	hsa-miR-4649-3p	CLIP-seq
MIRT1033059	hsa-miR-4659a-3p	CLIP-seq
MIRT1033060	hsa-miR-4659b-3p	CLIP-seq
MIRT1033061	hsa-miR-4677-5p	CLIP-seq
MIRT1033062	hsa-miR-4680-5p	CLIP-seq
MIRT1033063	hsa-miR-4685-5p	CLIP-seq
MIRT1033064	hsa-miR-4706	CLIP-seq
MIRT1033065	hsa-miR-4709-5p	CLIP-seq
MIRT1033066	hsa-miR-4719	CLIP-seq
MIRT1033067	hsa-miR-4724-5p	CLIP-seq
MIRT1033068	hsa-miR-4726-3p	CLIP-seq
MIRT1033069	hsa-miR-4732-3p	CLIP-seq
MIRT1033070	hsa-miR-4735-5p	CLIP-seq
MIRT1033071	hsa-miR-4742-3p	CLIP-seq
MIRT1033072	hsa-miR-4747-5p	CLIP-seq
MIRT1033073	hsa-miR-4749-5p	CLIP-seq
MIRT1033074	hsa-miR-4752	CLIP-seq
MIRT1033075	hsa-miR-4755-3p	CLIP-seq
MIRT1033076	hsa-miR-4761-5p	CLIP-seq
MIRT1033077	hsa-miR-4766-3p	CLIP-seq
MIRT1033078	hsa-miR-4781-5p	CLIP-seq
MIRT1033079	hsa-miR-4782-5p	CLIP-seq
MIRT1033080	hsa-miR-4789-5p	CLIP-seq
MIRT1033081	hsa-miR-4793-3p	CLIP-seq
MIRT1033082	hsa-miR-4796-5p	CLIP-seq
MIRT1033083	hsa-miR-484	CLIP-seq
MIRT1033084	hsa-miR-489	CLIP-seq
MIRT1033085	hsa-miR-498	CLIP-seq
MIRT1033086	hsa-miR-499-3p	CLIP-seq
MIRT1033087	hsa-miR-499a-3p	CLIP-seq
MIRT1033088	hsa-miR-505	CLIP-seq
MIRT1033089	hsa-miR-507	CLIP-seq
MIRT1033090	hsa-miR-516b	CLIP-seq
MIRT1033091	hsa-miR-520g	CLIP-seq
MIRT1033092	hsa-miR-520h	CLIP-seq
MIRT1033093	hsa-miR-542-3p	CLIP-seq
MIRT1033094	hsa-miR-543	CLIP-seq
MIRT1033095	hsa-miR-548n	CLIP-seq
MIRT1033096	hsa-miR-548o	CLIP-seq
MIRT1033097	hsa-miR-548p	CLIP-seq
MIRT1033098	hsa-miR-548t	CLIP-seq
MIRT1033099	hsa-miR-548u	CLIP-seq
MIRT1033100	hsa-miR-557	CLIP-seq
MIRT1033101	hsa-miR-558	CLIP-seq
MIRT1033102	hsa-miR-570	CLIP-seq
MIRT1033103	hsa-miR-576-5p	CLIP-seq
MIRT1033104	hsa-miR-579	CLIP-seq
MIRT1033105	hsa-miR-598	CLIP-seq
MIRT1033106	hsa-miR-618	CLIP-seq
MIRT1033107	hsa-miR-620	CLIP-seq
MIRT1033108	hsa-miR-626	CLIP-seq
MIRT1033109	hsa-miR-645	CLIP-seq
MIRT1033110	hsa-miR-670	CLIP-seq
MIRT1033111	hsa-miR-758	CLIP-seq
MIRT1033112	hsa-miR-764	CLIP-seq
MIRT1033113	hsa-miR-875-3p	CLIP-seq
MIRT1033039	hsa-miR-4275	CLIP-seq
MIRT1033059	hsa-miR-4659a-3p	CLIP-seq
MIRT1033060	hsa-miR-4659b-3p	CLIP-seq
MIRT1033076	hsa-miR-4761-5p	CLIP-seq
MIRT1033077	hsa-miR-4766-3p	CLIP-seq
MIRT1033097	hsa-miR-548p	CLIP-seq
MIRT1556475	hsa-miR-4802-3p	CLIP-seq
MIRT1033006	hsa-miR-151-3p	CLIP-seq
MIRT2006464	hsa-miR-15a	CLIP-seq
MIRT2006465	hsa-miR-15b	CLIP-seq
MIRT2006466	hsa-miR-16	CLIP-seq
MIRT2006467	hsa-miR-195	CLIP-seq
MIRT2006468	hsa-miR-214	CLIP-seq
MIRT2006469	hsa-miR-27a	CLIP-seq
MIRT2006470	hsa-miR-27b	CLIP-seq
MIRT1033020	hsa-miR-31	CLIP-seq
MIRT2006471	hsa-miR-3136-3p	CLIP-seq
MIRT2006472	hsa-miR-3137	CLIP-seq
MIRT2006473	hsa-miR-34b	CLIP-seq
MIRT2006474	hsa-miR-3619-5p	CLIP-seq
MIRT1033032	hsa-miR-3913-3p	CLIP-seq
MIRT2006475	hsa-miR-424	CLIP-seq
MIRT2006476	hsa-miR-4326	CLIP-seq
MIRT2006477	hsa-miR-4435	CLIP-seq
MIRT1033047	hsa-miR-4463	CLIP-seq
MIRT1033051	hsa-miR-4499	CLIP-seq
MIRT1033052	hsa-miR-4504	CLIP-seq
MIRT1033053	hsa-miR-4513	CLIP-seq
MIRT2006478	hsa-miR-4527	CLIP-seq
MIRT1033063	hsa-miR-4685-5p	CLIP-seq
MIRT2006479	hsa-miR-4705	CLIP-seq
MIRT2006480	hsa-miR-4731-5p	CLIP-seq
MIRT2006481	hsa-miR-4768-5p	CLIP-seq
MIRT1033084	hsa-miR-489	CLIP-seq
MIRT2006482	hsa-miR-497	CLIP-seq
MIRT2006483	hsa-miR-513a-5p	CLIP-seq
MIRT2006484	hsa-miR-545	CLIP-seq
MIRT2006485	hsa-miR-578	CLIP-seq
MIRT1033104	hsa-miR-579	CLIP-seq
MIRT2006486	hsa-miR-671-3p	CLIP-seq
MIRT2006487	hsa-miR-761	CLIP-seq
MIRT2006488	hsa-miR-942	CLIP-seq
MIRT2238918	hsa-miR-1237	CLIP-seq
MIRT1033007	hsa-miR-181a	CLIP-seq
MIRT1033008	hsa-miR-181b	CLIP-seq
MIRT1033009	hsa-miR-181c	CLIP-seq
MIRT1033010	hsa-miR-181d	CLIP-seq
MIRT2238919	hsa-miR-221	CLIP-seq
MIRT2238920	hsa-miR-222	CLIP-seq
MIRT2238921	hsa-miR-330-3p	CLIP-seq
MIRT1033037	hsa-miR-4262	CLIP-seq
MIRT2238922	hsa-miR-513c	CLIP-seq
MIRT2238923	hsa-miR-514b-5p	CLIP-seq
MIRT2238924	hsa-miR-633	CLIP-seq
MIRT2238918	hsa-miR-1237	CLIP-seq
MIRT2238925	hsa-miR-1245	CLIP-seq
MIRT2006464	hsa-miR-15a	CLIP-seq
MIRT2006465	hsa-miR-15b	CLIP-seq
MIRT2006466	hsa-miR-16	CLIP-seq
MIRT1033007	hsa-miR-181a	CLIP-seq
MIRT1033008	hsa-miR-181b	CLIP-seq
MIRT1033009	hsa-miR-181c	CLIP-seq
MIRT1033010	hsa-miR-181d	CLIP-seq
MIRT2006467	hsa-miR-195	CLIP-seq
MIRT2006468	hsa-miR-214	CLIP-seq
MIRT2238919	hsa-miR-221	CLIP-seq
MIRT2238920	hsa-miR-222	CLIP-seq
MIRT2238921	hsa-miR-330-3p	CLIP-seq
MIRT2238926	hsa-miR-338-5p	CLIP-seq
MIRT2006474	hsa-miR-3619-5p	CLIP-seq
MIRT2006475	hsa-miR-424	CLIP-seq
MIRT1033037	hsa-miR-4262	CLIP-seq
MIRT1033045	hsa-miR-4438	CLIP-seq
MIRT2006482	hsa-miR-497	CLIP-seq
MIRT2006483	hsa-miR-513a-5p	CLIP-seq
MIRT2238922	hsa-miR-513c	CLIP-seq
MIRT2238923	hsa-miR-514b-5p	CLIP-seq
MIRT1033094	hsa-miR-543	CLIP-seq
MIRT2238927	hsa-miR-548m	CLIP-seq
MIRT2006487	hsa-miR-761	CLIP-seq
MIRT2388751	hsa-miR-3919	CLIP-seq
MIRT2388752	hsa-miR-539	CLIP-seq
MIRT1033020	hsa-miR-31	CLIP-seq
MIRT2006473	hsa-miR-34b	CLIP-seq
MIRT2006476	hsa-miR-4326	CLIP-seq
MIRT1033063	hsa-miR-4685-5p	CLIP-seq
MIRT2006479	hsa-miR-4705	CLIP-seq
MIRT2006481	hsa-miR-4768-5p	CLIP-seq
MIRT2006485	hsa-miR-578	CLIP-seq
MIRT1033104	hsa-miR-579	CLIP-seq
MIRT2006486	hsa-miR-671-3p	CLIP-seq
MIRT2006488	hsa-miR-942	CLIP-seq
MIRT2542829	hsa-miR-103a	CLIP-seq
MIRT2542830	hsa-miR-107	CLIP-seq
MIRT2542831	hsa-miR-1184	CLIP-seq
MIRT2542832	hsa-miR-124	CLIP-seq
MIRT2542833	hsa-miR-1273d	CLIP-seq
MIRT2006464	hsa-miR-15a	CLIP-seq
MIRT2006465	hsa-miR-15b	CLIP-seq
MIRT2006466	hsa-miR-16	CLIP-seq
MIRT2542834	hsa-miR-1909	CLIP-seq
MIRT2006467	hsa-miR-195	CLIP-seq
MIRT2006468	hsa-miR-214	CLIP-seq
MIRT2542835	hsa-miR-2682	CLIP-seq
MIRT1033021	hsa-miR-3117-5p	CLIP-seq
MIRT2542836	hsa-miR-3136-5p	CLIP-seq
MIRT2542837	hsa-miR-3150b-3p	CLIP-seq
MIRT2542838	hsa-miR-3162-5p	CLIP-seq
MIRT2542839	hsa-miR-326	CLIP-seq
MIRT2542840	hsa-miR-330-5p	CLIP-seq
MIRT2006474	hsa-miR-3619-5p	CLIP-seq
MIRT2542841	hsa-miR-3714	CLIP-seq
MIRT2542842	hsa-miR-3910	CLIP-seq
MIRT2388751	hsa-miR-3919	CLIP-seq
MIRT2006475	hsa-miR-424	CLIP-seq
MIRT2542843	hsa-miR-4276	CLIP-seq
MIRT2006476	hsa-miR-4326	CLIP-seq
MIRT2542844	hsa-miR-4418	CLIP-seq
MIRT2542845	hsa-miR-4439	CLIP-seq
MIRT2542846	hsa-miR-4468	CLIP-seq
MIRT2542847	hsa-miR-449c	CLIP-seq
MIRT1033053	hsa-miR-4513	CLIP-seq
MIRT2542848	hsa-miR-4689	CLIP-seq
MIRT2542849	hsa-miR-4784	CLIP-seq
MIRT2542850	hsa-miR-4787-5p	CLIP-seq
MIRT2542851	hsa-miR-495	CLIP-seq
MIRT2006482	hsa-miR-497	CLIP-seq
MIRT2542852	hsa-miR-506	CLIP-seq
MIRT2542853	hsa-miR-509-3-5p	CLIP-seq
MIRT2542854	hsa-miR-509-5p	CLIP-seq
MIRT2388752	hsa-miR-539	CLIP-seq
MIRT2542855	hsa-miR-555	CLIP-seq
MIRT2542856	hsa-miR-563	CLIP-seq
MIRT1033109	hsa-miR-645	CLIP-seq
MIRT2542857	hsa-miR-720	CLIP-seq
MIRT2006487	hsa-miR-761	CLIP-seq
MIRT2542858	hsa-miR-943	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005158	Function	Insulin receptor binding	IBA	21873635
GO:0005158	Function	Insulin receptor binding	ISS	15664450
GO:0005515	Function	Protein binding	IPI	8798570, 9506989, 15060076, 15722337, 20670374, 20878056, 23246379, 24658140, 25814554, 31980649
GO:0005737	Component	Cytoplasm	TAS	9006901
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS	9006901
GO:0007411	Process	Axon guidance	TAS
GO:0008286	Process	Insulin receptor signaling pathway	IBA	21873635
GO:0030178	Process	Negative regulation of Wnt signaling pathway	IBA	21873635
GO:0030178	Process	Negative regulation of Wnt signaling pathway	IDA	17376403
GO:0030949	Process	Positive regulation of vascular endothelial growth factor receptor signaling pathway	IDA	15060076
GO:0032991	Component	Protein-containing complex	IDA	20878056
GO:0046325	Process	Negative regulation of glucose import	ISS	15664450
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	IBA	21873635
GO:0046627	Process	Negative regulation of insulin receptor signaling pathway	ISS	15664450
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	ISS	24746805

MIM	HGNC	e!Ensembl
601523	4564	ENSG00000106070

Protein

UniProt ID

Q13322

Protein name

Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Insulin receptor-binding protein Grb-IR)

Protein function

Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like grow

PDB

1NRV , 3HK0

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00788	RA	166 → 250	Ras association (RalGDS/AF-6) domain	Domain
PF00169	PH	291 → 399	PH domain	Domain
PF08947	BPS	425 → 471	BPS (Between PH and SH2)	Domain
PF00017	SH2	493 → 574	SH2 domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed in fetal and adult tissues, including fetal and postnatal liver, lung, kidney, skeletal muscle, heart, spleen, skin and brain. {ECO:0000269|PubMed:11527390}.

Sequence

MALAGCPDSFLHHPYYQDKVEQTPRSQQDPAGPGLPAQSDRLANHQEDDVDLEALVNDMN
ASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHILAV
RRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSK
VVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVESTMASE
SKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNSSSCPEIQGFLHVK
ELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQYNAPTDH
GLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKALLSPF
STPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRSTRMNILGSQSPLHP
STLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIK
NFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL

Sequence length

594

Interactions

View interactions

	KEGG		Reactome
	mTOR signaling pathway		Signaling by SCF-KIT IRS activation Signal attenuation Insulin receptor signalling cascade RET signaling

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Lymphoblastic leukemia	Precursor Cell Lymphoblastic Leukemia Lymphoma	rs387906351, rs104894562, rs398122513, rs398122840, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699 View all (13 more)	23512250
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	25223841

Show/Hide Unknown Diseases (5)

Disease term	Disease name	Evidence	Source
Unknown
Diabetes	Diabetes		GWAS
Lung adenocarcinoma	Lung adenocarcinoma	Validation that loss of Tgfbr2 results in more aggressive and T cell-excluded KP lung tumors	GWAS, CBGDA
Gout	Gout		GWAS
Oligodendroglioma	Oligodendroglioma		GWAS
Prostate cancer	Prostate cancer	Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population.	GWAS, CBGDA

Show/Hide Text Mining Associations (29)

Disease Name	Relationship Type	References
Associations from Text Mining
Abnormalities Drug Induced	Associate	27370225
Achondroplasia	Associate	27370225
Alzheimer Disease	Associate	25391383
Brain Injuries Traumatic	Associate	35571247
Breast Neoplasms	Associate	25560175
Bronchopulmonary Dysplasia	Stimulate	39988826
Carcinoma Ovarian Epithelial	Associate	24190013
Colorectal Neoplasms	Associate	21978709, 35924107, 37535601
Desmoplastic Small Round Cell Tumor	Associate	25119929
Diabetes Mellitus	Associate	25375650
Diabetes Mellitus Type 2	Associate	23552671, 26418287, 37356726
Dwarfism Pituitary	Associate	27651465
Flaujeac factor deficiency	Associate	27370225
Growth Disorders	Associate	27370225, 33187293
Heart Defects Congenital	Associate	33407475
Hemochromatosis	Associate	23761422
Immune System Diseases	Associate	35571247
Intervertebral Disc Degeneration	Inhibit	29476072
Lung Neoplasms	Stimulate	34906185
Melanoma	Associate	36716920
Muscular Dystrophy Facioscapulohumeral	Associate	18167544
Neoplasm Metastasis	Associate	36716920
Neoplasms	Associate	23792563, 25560175, 32448196, 35924107
Nerve Degeneration	Associate	35571247
Neuroblastoma	Associate	23034519
Parkinson Disease Secondary	Associate	27861377
Pseudohypoparathyroidism	Associate	22679513
Sarcoma Ewing	Associate	25119929
Silver Russell Syndrome	Associate	10856193, 33187293

GRB10 (growth factor receptor bound protein 10)