Gene Gene information from NCBI Gene database.
Entrez ID 285704
Gene name Repulsive guidance molecule BMP co-receptor b
Gene symbol RGMB
Synonyms (NCBI Gene)
DRAGON
Chromosome 5
Chromosome location 5q15
Summary RGMB is a glycosylphosphatidylinositol (GPI)-anchored member of the repulsive guidance molecule family (see RGMA, MIM 607362) and contributes to the patterning of the developing nervous system (Samad et al., 2005 [PubMed 15671031]).[supplied by OMIM, Apr
miRNA miRNA information provided by mirtarbase database.
588
miRTarBase ID miRNA Experiments Reference
MIRT016098 hsa-miR-769-5p Sequencing 20371350
MIRT016114 hsa-miR-421 Sequencing 20371350
MIRT023409 hsa-miR-30b-5p Sequencing 20371350
MIRT046176 hsa-miR-27b-3p CLASH 23622248
MIRT044170 hsa-miR-130b-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25938661
GO:0005793 Component Endoplasmic reticulum-Golgi intermediate compartment IEA
GO:0005793 Component Endoplasmic reticulum-Golgi intermediate compartment ISS
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612687 26896 ENSG00000174136
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6NW40
Protein name Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)
Protein function Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Pro
PDB 4BQ6 , 4BQ7 , 4BQ8 , 4UHZ , 4UI0 , 4UI2 , 6Z3H , 6Z3J , 6Z3M
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06535 RGM_N 54 222 Repulsive guidance molecule (RGM) N-terminus Family
PF06534 RGM_C 226 400 Repulsive guidance molecule (RGM) C-terminus Family
Sequence
Sequence length 437
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  TGF-beta signaling pathway