Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2857
Gene name Gene Name - the full gene name approved by the HGNC.
G protein-coupled receptor 34
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GPR34
Synonyms (NCBI Gene) Gene synonyms aliases
LPS1, LYPSR1
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp11.4
Summary Summary of gene provided in NCBI Entrez Gene.
G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activ
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018922 hsa-miR-335-5p Microarray 18185580
MIRT733183 hsa-miR-4646-5p Immunohistochemistry (IHC), Immunoprecipitaion (IP), Luciferase reporter assay, qRT-PCR, Western blotting 33875796
MIRT1031327 hsa-miR-300 CLIP-seq
MIRT1031328 hsa-miR-381 CLIP-seq
MIRT1031329 hsa-miR-4719 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity TAS 10036181
GO:0005887 Component Integral component of plasma membrane TAS 10036181
GO:0007186 Process G protein-coupled receptor signaling pathway IBA 21873635
GO:0035589 Process G protein-coupled purinergic nucleotide receptor signaling pathway IEA
GO:0045028 Function G protein-coupled purinergic nucleotide receptor activity IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
300241 4490 ENSG00000171659
Protein
UniProt ID Q9UPC5
Protein name Probable G-protein coupled receptor 34
Protein function G-protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response (PubMed:16460680). Acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils (By similarity). Mech
PDB 8IYX , 8IZ4 , 8K4N , 8SAI , 8WRB , 8XBE , 8XBG , 8XBH , 8XBI
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 71 327 7 transmembrane receptor (rhodopsin family) Family
Tissue specificity TISSUE SPECIFICITY: Broadly expressed. Highly expressed on mast cells (PubMed:16460680). {ECO:0000269|PubMed:16460680}.
Sequence
Sequence length 381
Interactions View interactions