Gene Gene information from NCBI Gene database.
Entrez ID 2850
Gene name G protein-coupled receptor 27
Gene symbol GPR27
Synonyms (NCBI Gene)
SREB1
Chromosome 3
Chromosome location 3p13
Summary GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light in
miRNA miRNA information provided by mirtarbase database.
391
miRTarBase ID miRNA Experiments Reference
MIRT029011 hsa-miR-26b-5p Microarray 19088304
MIRT557508 hsa-miR-1537-3p PAR-CLIP 20371350
MIRT557507 hsa-miR-548a-5p PAR-CLIP 20371350
MIRT557506 hsa-miR-548ab PAR-CLIP 20371350
MIRT557505 hsa-miR-548ad-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity IBA
GO:0004930 Function G protein-coupled receptor activity IEA
GO:0004930 Function G protein-coupled receptor activity TAS 10833454
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605187 4482 ENSG00000170837
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9NS67
Protein name Probable G-protein coupled receptor 27 (Super conserved receptor expressed in brain 1)
Protein function Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 35 337 7 transmembrane receptor (rhodopsin family) Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, de
Sequence
Sequence length 375
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production