GPR27 (G protein-coupled receptor 27)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2850
Gene name Gene Name - the full gene name approved by the HGNC.
G protein-coupled receptor 27
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GPR27
Synonyms (NCBI Gene) Gene synonyms aliases
SREB1
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p13
Summary Summary of gene provided in NCBI Entrez Gene.
GPR27 is a member of the G protein-coupled receptors (GPCRs), a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light in
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(391)
miRTarBase ID miRNA Experiments Reference
MIRT029011 hsa-miR-26b-5p Microarray 19088304
MIRT557508 hsa-miR-1537-3p PAR-CLIP 20371350
MIRT557507 hsa-miR-548a-5p PAR-CLIP 20371350
MIRT557506 hsa-miR-548ab PAR-CLIP 20371350
MIRT557505 hsa-miR-548ad-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(8)
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity IBA 21873635
GO:0005886 Component Plasma membrane IBA 21873635
GO:0005886 Component Plasma membrane TAS
GO:0007165 Process Signal transduction TAS 10833454
GO:0007186 Process G protein-coupled receptor signaling pathway TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
605187 4482 ENSG00000170837
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q9NS67
Protein name Probable G-protein coupled receptor 27 (Super conserved receptor expressed in brain 1)
Protein function Orphan receptor. Possible candidate for amine-like G-protein coupled receptor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 35 → 337 7 transmembrane receptor (rhodopsin family) Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, de
Sequence
Sequence length 375
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  Reactome
    G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Restless Legs Syndrome Restless Legs Syndrome GWAS
Show/Hide Text Mining Associations (8)
Associations from Text Mining
Disease Name Relationship Type References
Blepharophimosis Associate 19332160
Contracture Associate 19332160
Inflammation Associate 27430610
Meningism Associate 27430610
Neoplasms Associate 37702614
Ovarian Neoplasms Associate 40270229
Parkinson Disease Associate 36869069
Stomach Neoplasms Associate 37702614