GPR26 (G protein-coupled receptor 26)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2849 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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G protein-coupled receptor 26 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GPR26 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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10 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10q26.13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a G protein-couple receptor protein. G-protein-coupled receptors are a large family of membrane proteins that are involved in cellular responses to environmental stimuli, neurotransmitters, and hormones. The encoded protein may play a ro |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q8NDV2 | ||||||||||
Protein name | G-protein coupled receptor 26 | ||||||||||
Protein function | Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma. {ECO:0000269|PubMed:17363172, ECO:0000269|PubMed:18037267}. | ||||||||||
Sequence | |||||||||||
Sequence length | 337 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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