Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
2849
Gene name Gene Name - the full gene name approved by the HGNC.
G protein-coupled receptor 26
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
GPR26
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q26.13
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a G protein-couple receptor protein. G-protein-coupled receptors are a large family of membrane proteins that are involved in cellular responses to environmental stimuli, neurotransmitters, and hormones. The encoded protein may play a ro
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT725493 hsa-miR-331-3p HITS-CLIP 19536157
MIRT657670 hsa-miR-1250-3p HITS-CLIP 19536157
MIRT725491 hsa-miR-6801-3p HITS-CLIP 19536157
MIRT725492 hsa-miR-6810-3p HITS-CLIP 19536157
MIRT725490 hsa-miR-4292 HITS-CLIP 19536157
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0004930 Function G protein-coupled receptor activity IBA 21873635
GO:0004930 Function G protein-coupled receptor activity IDA 17363172
GO:0005886 Component Plasma membrane IEA
GO:0007186 Process G protein-coupled receptor signaling pathway IBA 21873635
GO:0007189 Process Adenylate cyclase-activating G protein-coupled receptor signaling pathway IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604847 4481 ENSG00000154478
Protein
UniProt ID Q8NDV2
Protein name G-protein coupled receptor 26
Protein function Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1 22 294 7 transmembrane receptor (rhodopsin family) Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma. {ECO:0000269|PubMed:17363172, ECO:0000269|PubMed:18037267}.
Sequence
Sequence length 337
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959