Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	283871
Gene name Gene Name - the full gene name approved by the HGNC.	Phosphoglycolate phosphatase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PGP
Synonyms (NCBI Gene) Gene synonyms aliases	AUM, G3PP, PGPase
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16p13.3

Show/Hide all(342)

miRTarBase ID	miRNA	Experiments	Reference
MIRT048822	hsa-miR-93-5p	CLASH	23622248
MIRT1227962	hsa-miR-106a	CLIP-seq
MIRT1227963	hsa-miR-106b	CLIP-seq
MIRT1227964	hsa-miR-1197	CLIP-seq
MIRT1227965	hsa-miR-1233	CLIP-seq
MIRT1227966	hsa-miR-1255a	CLIP-seq
MIRT1227967	hsa-miR-1255b	CLIP-seq
MIRT1227968	hsa-miR-125a-5p	CLIP-seq
MIRT1227969	hsa-miR-125b	CLIP-seq
MIRT1227970	hsa-miR-1273e	CLIP-seq
MIRT1227971	hsa-miR-1287	CLIP-seq
MIRT1227972	hsa-miR-1305	CLIP-seq
MIRT1227973	hsa-miR-1321	CLIP-seq
MIRT1227974	hsa-miR-134	CLIP-seq
MIRT1227975	hsa-miR-140-5p	CLIP-seq
MIRT1227976	hsa-miR-15a	CLIP-seq
MIRT1227977	hsa-miR-15b	CLIP-seq
MIRT1227978	hsa-miR-16	CLIP-seq
MIRT1227979	hsa-miR-17	CLIP-seq
MIRT1227980	hsa-miR-1910	CLIP-seq
MIRT1227981	hsa-miR-1913	CLIP-seq
MIRT1227982	hsa-miR-1915	CLIP-seq
MIRT1227983	hsa-miR-195	CLIP-seq
MIRT1227984	hsa-miR-20a	CLIP-seq
MIRT1227985	hsa-miR-20b	CLIP-seq
MIRT1227986	hsa-miR-2114	CLIP-seq
MIRT1227987	hsa-miR-22	CLIP-seq
MIRT1227988	hsa-miR-2467-3p	CLIP-seq
MIRT1227989	hsa-miR-2467-5p	CLIP-seq
MIRT1227990	hsa-miR-30a	CLIP-seq
MIRT1227991	hsa-miR-30b	CLIP-seq
MIRT1227992	hsa-miR-30c	CLIP-seq
MIRT1227993	hsa-miR-30d	CLIP-seq
MIRT1227994	hsa-miR-30e	CLIP-seq
MIRT1227995	hsa-miR-31	CLIP-seq
MIRT1227996	hsa-miR-3118	CLIP-seq
MIRT1227997	hsa-miR-3121-5p	CLIP-seq
MIRT1227998	hsa-miR-3136-5p	CLIP-seq
MIRT1227999	hsa-miR-3140-5p	CLIP-seq
MIRT1228000	hsa-miR-3145-5p	CLIP-seq
MIRT1228001	hsa-miR-3151	CLIP-seq
MIRT1228002	hsa-miR-3157-5p	CLIP-seq
MIRT1228003	hsa-miR-3162-3p	CLIP-seq
MIRT1228004	hsa-miR-3163	CLIP-seq
MIRT1228005	hsa-miR-3164	CLIP-seq
MIRT1228006	hsa-miR-3177-3p	CLIP-seq
MIRT1228007	hsa-miR-3184	CLIP-seq
MIRT1228008	hsa-miR-3187-3p	CLIP-seq
MIRT1228009	hsa-miR-3188	CLIP-seq
MIRT1228010	hsa-miR-3189-3p	CLIP-seq
MIRT1228011	hsa-miR-3192	CLIP-seq
MIRT1228012	hsa-miR-324-3p	CLIP-seq
MIRT1228013	hsa-miR-329	CLIP-seq
MIRT1228014	hsa-miR-3607-3p	CLIP-seq
MIRT1228015	hsa-miR-3616-3p	CLIP-seq
MIRT1228016	hsa-miR-362-3p	CLIP-seq
MIRT1228017	hsa-miR-3652	CLIP-seq
MIRT1228018	hsa-miR-3660	CLIP-seq
MIRT1228019	hsa-miR-3678-3p	CLIP-seq
MIRT1228020	hsa-miR-3686	CLIP-seq
MIRT1228021	hsa-miR-3689a-3p	CLIP-seq
MIRT1228022	hsa-miR-3689c	CLIP-seq
MIRT1228023	hsa-miR-3689d	CLIP-seq
MIRT1228024	hsa-miR-3926	CLIP-seq
MIRT1228025	hsa-miR-3973	CLIP-seq
MIRT1228026	hsa-miR-3975	CLIP-seq
MIRT1228027	hsa-miR-3977	CLIP-seq
MIRT1228028	hsa-miR-423-5p	CLIP-seq
MIRT1228029	hsa-miR-424	CLIP-seq
MIRT1228030	hsa-miR-4264	CLIP-seq
MIRT1228031	hsa-miR-4275	CLIP-seq
MIRT1228032	hsa-miR-4297	CLIP-seq
MIRT1228033	hsa-miR-4308	CLIP-seq
MIRT1228034	hsa-miR-4313	CLIP-seq
MIRT1228035	hsa-miR-4318	CLIP-seq
MIRT1228036	hsa-miR-4319	CLIP-seq
MIRT1228037	hsa-miR-4420	CLIP-seq
MIRT1228038	hsa-miR-4430	CLIP-seq
MIRT1228039	hsa-miR-4435	CLIP-seq
MIRT1228040	hsa-miR-4436a	CLIP-seq
MIRT1228041	hsa-miR-4436b-3p	CLIP-seq
MIRT1228042	hsa-miR-4439	CLIP-seq
MIRT1228043	hsa-miR-4447	CLIP-seq
MIRT1228044	hsa-miR-4472	CLIP-seq
MIRT1228045	hsa-miR-4475	CLIP-seq
MIRT1228046	hsa-miR-4492	CLIP-seq
MIRT1228047	hsa-miR-4498	CLIP-seq
MIRT1228048	hsa-miR-4513	CLIP-seq
MIRT1228049	hsa-miR-4524	CLIP-seq
MIRT1228050	hsa-miR-4526	CLIP-seq
MIRT1228051	hsa-miR-4537	CLIP-seq
MIRT1228052	hsa-miR-455-3p	CLIP-seq
MIRT1228053	hsa-miR-4640-5p	CLIP-seq
MIRT1228054	hsa-miR-4643	CLIP-seq
MIRT1228055	hsa-miR-4649-3p	CLIP-seq
MIRT1228056	hsa-miR-4650-5p	CLIP-seq
MIRT1228057	hsa-miR-4652-5p	CLIP-seq
MIRT1228058	hsa-miR-4693-3p	CLIP-seq
MIRT1228059	hsa-miR-4700-3p	CLIP-seq
MIRT1228060	hsa-miR-4701-5p	CLIP-seq
MIRT1228061	hsa-miR-4710	CLIP-seq
MIRT1228062	hsa-miR-4720-3p	CLIP-seq
MIRT1228063	hsa-miR-4721	CLIP-seq
MIRT1228064	hsa-miR-4722-3p	CLIP-seq
MIRT1228065	hsa-miR-4726-3p	CLIP-seq
MIRT1228066	hsa-miR-4726-5p	CLIP-seq
MIRT1228067	hsa-miR-4728-5p	CLIP-seq
MIRT1228068	hsa-miR-4732-3p	CLIP-seq
MIRT1228069	hsa-miR-4733-5p	CLIP-seq
MIRT1228070	hsa-miR-4739	CLIP-seq
MIRT1228071	hsa-miR-4749-3p	CLIP-seq
MIRT1228072	hsa-miR-4755-3p	CLIP-seq
MIRT1228073	hsa-miR-4756-5p	CLIP-seq
MIRT1228074	hsa-miR-4763-5p	CLIP-seq
MIRT1228075	hsa-miR-4764-3p	CLIP-seq
MIRT1228076	hsa-miR-4792	CLIP-seq
MIRT1228077	hsa-miR-4804-3p	CLIP-seq
MIRT1228078	hsa-miR-485-5p	CLIP-seq
MIRT1228079	hsa-miR-491-5p	CLIP-seq
MIRT1228080	hsa-miR-497	CLIP-seq
MIRT1228081	hsa-miR-498	CLIP-seq
MIRT1228082	hsa-miR-502-5p	CLIP-seq
MIRT1228083	hsa-miR-503	CLIP-seq
MIRT1228084	hsa-miR-507	CLIP-seq
MIRT1228085	hsa-miR-512-3p	CLIP-seq
MIRT1228086	hsa-miR-519a	CLIP-seq
MIRT1228087	hsa-miR-519b-3p	CLIP-seq
MIRT1228088	hsa-miR-519c-3p	CLIP-seq
MIRT1228089	hsa-miR-519d	CLIP-seq
MIRT1228090	hsa-miR-520g	CLIP-seq
MIRT1228091	hsa-miR-520h	CLIP-seq
MIRT1228092	hsa-miR-532-5p	CLIP-seq
MIRT1228093	hsa-miR-544b	CLIP-seq
MIRT1228094	hsa-miR-548a-3p	CLIP-seq
MIRT1228095	hsa-miR-548ac	CLIP-seq
MIRT1228096	hsa-miR-548ae	CLIP-seq
MIRT1228097	hsa-miR-548aj	CLIP-seq
MIRT1228098	hsa-miR-548am	CLIP-seq
MIRT1228099	hsa-miR-548d-3p	CLIP-seq
MIRT1228100	hsa-miR-548e	CLIP-seq
MIRT1228101	hsa-miR-548f	CLIP-seq
MIRT1228102	hsa-miR-548n	CLIP-seq
MIRT1228103	hsa-miR-548s	CLIP-seq
MIRT1228104	hsa-miR-548t	CLIP-seq
MIRT1228105	hsa-miR-548x	CLIP-seq
MIRT1228106	hsa-miR-548z	CLIP-seq
MIRT1228107	hsa-miR-557	CLIP-seq
MIRT1228108	hsa-miR-582-3p	CLIP-seq
MIRT1228109	hsa-miR-588	CLIP-seq
MIRT1228110	hsa-miR-596	CLIP-seq
MIRT1228111	hsa-miR-642a	CLIP-seq
MIRT1228112	hsa-miR-646	CLIP-seq
MIRT1228113	hsa-miR-661	CLIP-seq
MIRT1228114	hsa-miR-670	CLIP-seq
MIRT1228115	hsa-miR-759	CLIP-seq
MIRT1228116	hsa-miR-762	CLIP-seq
MIRT1228117	hsa-miR-93	CLIP-seq
MIRT1228118	hsa-miR-941	CLIP-seq
MIRT1228119	hsa-miR-943	CLIP-seq
MIRT1227965	hsa-miR-1233	CLIP-seq
MIRT1227966	hsa-miR-1255a	CLIP-seq
MIRT1227967	hsa-miR-1255b	CLIP-seq
MIRT1227998	hsa-miR-3136-5p	CLIP-seq
MIRT1228018	hsa-miR-3660	CLIP-seq
MIRT1228033	hsa-miR-4308	CLIP-seq
MIRT1228042	hsa-miR-4439	CLIP-seq
MIRT1228048	hsa-miR-4513	CLIP-seq
MIRT1228050	hsa-miR-4526	CLIP-seq
MIRT2066699	hsa-miR-103a	CLIP-seq
MIRT2066700	hsa-miR-107	CLIP-seq
MIRT2066701	hsa-miR-1184	CLIP-seq
MIRT2066702	hsa-miR-1205	CLIP-seq
MIRT1227965	hsa-miR-1233	CLIP-seq
MIRT1227966	hsa-miR-1255a	CLIP-seq
MIRT1227967	hsa-miR-1255b	CLIP-seq
MIRT1227968	hsa-miR-125a-5p	CLIP-seq
MIRT1227969	hsa-miR-125b	CLIP-seq
MIRT2066703	hsa-miR-1291	CLIP-seq
MIRT2066704	hsa-miR-1587	CLIP-seq
MIRT1227976	hsa-miR-15a	CLIP-seq
MIRT1227977	hsa-miR-15b	CLIP-seq
MIRT1227978	hsa-miR-16	CLIP-seq
MIRT1227981	hsa-miR-1913	CLIP-seq
MIRT1227983	hsa-miR-195	CLIP-seq
MIRT1227987	hsa-miR-22	CLIP-seq
MIRT1227998	hsa-miR-3136-5p	CLIP-seq
MIRT2066705	hsa-miR-3173-5p	CLIP-seq
MIRT2066706	hsa-miR-3186-5p	CLIP-seq
MIRT1228011	hsa-miR-3192	CLIP-seq
MIRT2066707	hsa-miR-3194-3p	CLIP-seq
MIRT1228012	hsa-miR-324-3p	CLIP-seq
MIRT2066708	hsa-miR-328	CLIP-seq
MIRT2066709	hsa-miR-3622a-3p	CLIP-seq
MIRT2066710	hsa-miR-3622b-3p	CLIP-seq
MIRT1228018	hsa-miR-3660	CLIP-seq
MIRT2066711	hsa-miR-3670	CLIP-seq
MIRT2066712	hsa-miR-3672	CLIP-seq
MIRT2066713	hsa-miR-370	CLIP-seq
MIRT2066714	hsa-miR-378g	CLIP-seq
MIRT2066715	hsa-miR-3921	CLIP-seq
MIRT2066716	hsa-miR-3940-3p	CLIP-seq
MIRT1228025	hsa-miR-3973	CLIP-seq
MIRT1228029	hsa-miR-424	CLIP-seq
MIRT2066717	hsa-miR-4276	CLIP-seq
MIRT2066718	hsa-miR-4303	CLIP-seq
MIRT1228033	hsa-miR-4308	CLIP-seq
MIRT1228036	hsa-miR-4319	CLIP-seq
MIRT2066719	hsa-miR-4418	CLIP-seq
MIRT1228042	hsa-miR-4439	CLIP-seq
MIRT1228046	hsa-miR-4492	CLIP-seq
MIRT2066720	hsa-miR-4493	CLIP-seq
MIRT1228047	hsa-miR-4498	CLIP-seq
MIRT1228048	hsa-miR-4513	CLIP-seq
MIRT1228049	hsa-miR-4524	CLIP-seq
MIRT1228050	hsa-miR-4526	CLIP-seq
MIRT2066721	hsa-miR-4642	CLIP-seq
MIRT2066722	hsa-miR-4653-5p	CLIP-seq
MIRT2066723	hsa-miR-4656	CLIP-seq
MIRT2066724	hsa-miR-4663	CLIP-seq
MIRT2066725	hsa-miR-4675	CLIP-seq
MIRT2066726	hsa-miR-4741	CLIP-seq
MIRT2066727	hsa-miR-4793-3p	CLIP-seq
MIRT1228080	hsa-miR-497	CLIP-seq
MIRT1228083	hsa-miR-503	CLIP-seq
MIRT2066728	hsa-miR-509-3-5p	CLIP-seq
MIRT2066729	hsa-miR-509-5p	CLIP-seq
MIRT1228090	hsa-miR-520g	CLIP-seq
MIRT1228091	hsa-miR-520h	CLIP-seq
MIRT1228095	hsa-miR-548ac	CLIP-seq
MIRT1228096	hsa-miR-548ae	CLIP-seq
MIRT1228097	hsa-miR-548aj	CLIP-seq
MIRT1228098	hsa-miR-548am	CLIP-seq
MIRT1228099	hsa-miR-548d-3p	CLIP-seq
MIRT1228105	hsa-miR-548x	CLIP-seq
MIRT1228106	hsa-miR-548z	CLIP-seq
MIRT1228108	hsa-miR-582-3p	CLIP-seq
MIRT2066730	hsa-miR-604	CLIP-seq
MIRT2066731	hsa-miR-618	CLIP-seq
MIRT2066732	hsa-miR-627	CLIP-seq
MIRT2066733	hsa-miR-642b	CLIP-seq
MIRT1228112	hsa-miR-646	CLIP-seq
MIRT1228116	hsa-miR-762	CLIP-seq
MIRT2066734	hsa-miR-924	CLIP-seq
MIRT1228118	hsa-miR-941	CLIP-seq
MIRT2066701	hsa-miR-1184	CLIP-seq
MIRT1227964	hsa-miR-1197	CLIP-seq
MIRT2066702	hsa-miR-1205	CLIP-seq
MIRT1227965	hsa-miR-1233	CLIP-seq
MIRT1227966	hsa-miR-1255a	CLIP-seq
MIRT1227967	hsa-miR-1255b	CLIP-seq
MIRT1227998	hsa-miR-3136-5p	CLIP-seq
MIRT2294346	hsa-miR-3152-5p	CLIP-seq
MIRT1228008	hsa-miR-3187-3p	CLIP-seq
MIRT1228011	hsa-miR-3192	CLIP-seq
MIRT2066707	hsa-miR-3194-3p	CLIP-seq
MIRT2294347	hsa-miR-3545-3p	CLIP-seq
MIRT1228018	hsa-miR-3660	CLIP-seq
MIRT2294348	hsa-miR-3663-5p	CLIP-seq
MIRT1228021	hsa-miR-3689a-3p	CLIP-seq
MIRT1228022	hsa-miR-3689c	CLIP-seq
MIRT1228023	hsa-miR-3689d	CLIP-seq
MIRT2294349	hsa-miR-374c	CLIP-seq
MIRT2294350	hsa-miR-3913-3p	CLIP-seq
MIRT2066715	hsa-miR-3921	CLIP-seq
MIRT2294351	hsa-miR-4252	CLIP-seq
MIRT2066717	hsa-miR-4276	CLIP-seq
MIRT2066718	hsa-miR-4303	CLIP-seq
MIRT1228033	hsa-miR-4308	CLIP-seq
MIRT2294352	hsa-miR-4425	CLIP-seq
MIRT1228039	hsa-miR-4435	CLIP-seq
MIRT1228042	hsa-miR-4439	CLIP-seq
MIRT2066720	hsa-miR-4493	CLIP-seq
MIRT2294353	hsa-miR-4504	CLIP-seq
MIRT2294354	hsa-miR-450b-3p	CLIP-seq
MIRT1228048	hsa-miR-4513	CLIP-seq
MIRT1228050	hsa-miR-4526	CLIP-seq
MIRT2294355	hsa-miR-4635	CLIP-seq
MIRT1228056	hsa-miR-4650-5p	CLIP-seq
MIRT2066722	hsa-miR-4653-5p	CLIP-seq
MIRT2294356	hsa-miR-4680-5p	CLIP-seq
MIRT1228060	hsa-miR-4701-5p	CLIP-seq
MIRT1228067	hsa-miR-4728-5p	CLIP-seq
MIRT1228069	hsa-miR-4733-5p	CLIP-seq
MIRT1228072	hsa-miR-4755-3p	CLIP-seq
MIRT2294357	hsa-miR-4774-3p	CLIP-seq
MIRT2294358	hsa-miR-489	CLIP-seq
MIRT2294359	hsa-miR-542-3p	CLIP-seq
MIRT1228103	hsa-miR-548s	CLIP-seq
MIRT1228109	hsa-miR-588	CLIP-seq
MIRT2066730	hsa-miR-604	CLIP-seq
MIRT2294360	hsa-miR-655	CLIP-seq
MIRT1228113	hsa-miR-661	CLIP-seq
MIRT2294361	hsa-miR-758	CLIP-seq
MIRT2294362	hsa-miR-769-3p	CLIP-seq
MIRT1227965	hsa-miR-1233	CLIP-seq
MIRT1227966	hsa-miR-1255a	CLIP-seq
MIRT1227967	hsa-miR-1255b	CLIP-seq
MIRT1227998	hsa-miR-3136-5p	CLIP-seq
MIRT2392448	hsa-miR-3620	CLIP-seq
MIRT1228018	hsa-miR-3660	CLIP-seq
MIRT1228033	hsa-miR-4308	CLIP-seq
MIRT1228042	hsa-miR-4439	CLIP-seq
MIRT1228048	hsa-miR-4513	CLIP-seq
MIRT1228050	hsa-miR-4526	CLIP-seq
MIRT2456303	hsa-miR-1281	CLIP-seq
MIRT1228011	hsa-miR-3192	CLIP-seq
MIRT2456304	hsa-miR-4300	CLIP-seq
MIRT2456305	hsa-miR-4691-5p	CLIP-seq
MIRT2456306	hsa-miR-920	CLIP-seq
MIRT1227972	hsa-miR-1305	CLIP-seq
MIRT1227970	hsa-miR-1273e	CLIP-seq
MIRT1227972	hsa-miR-1305	CLIP-seq
MIRT1227976	hsa-miR-15a	CLIP-seq
MIRT1227977	hsa-miR-15b	CLIP-seq
MIRT1227978	hsa-miR-16	CLIP-seq
MIRT1227983	hsa-miR-195	CLIP-seq
MIRT1228008	hsa-miR-3187-3p	CLIP-seq
MIRT1228010	hsa-miR-3189-3p	CLIP-seq
MIRT1228024	hsa-miR-3926	CLIP-seq
MIRT1228029	hsa-miR-424	CLIP-seq
MIRT1228039	hsa-miR-4435	CLIP-seq
MIRT1228049	hsa-miR-4524	CLIP-seq
MIRT1228051	hsa-miR-4537	CLIP-seq
MIRT1228054	hsa-miR-4643	CLIP-seq
MIRT1228060	hsa-miR-4701-5p	CLIP-seq
MIRT1228080	hsa-miR-497	CLIP-seq
MIRT1228082	hsa-miR-502-5p	CLIP-seq
MIRT1228083	hsa-miR-503	CLIP-seq
MIRT1228094	hsa-miR-548a-3p	CLIP-seq
MIRT1228095	hsa-miR-548ac	CLIP-seq
MIRT1228096	hsa-miR-548ae	CLIP-seq
MIRT1228097	hsa-miR-548aj	CLIP-seq
MIRT1228098	hsa-miR-548am	CLIP-seq
MIRT1228099	hsa-miR-548d-3p	CLIP-seq
MIRT1228100	hsa-miR-548e	CLIP-seq
MIRT1228101	hsa-miR-548f	CLIP-seq
MIRT1228103	hsa-miR-548s	CLIP-seq
MIRT1228105	hsa-miR-548x	CLIP-seq
MIRT1228106	hsa-miR-548z	CLIP-seq
MIRT1228108	hsa-miR-582-3p	CLIP-seq
MIRT1228109	hsa-miR-588	CLIP-seq
MIRT1228112	hsa-miR-646	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000121	Function	Sn-glycerol 1-phosphatase activity	IEA
GO:0000287	Function	Magnesium ion binding	IEA
GO:0000287	Function	Magnesium ion binding	ISS
GO:0004721	Function	Phosphoprotein phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	IEA
GO:0004725	Function	Protein tyrosine phosphatase activity	ISS
GO:0005737	Component	Cytoplasm	IBA
GO:0006114	Process	Glycerol biosynthetic process	IDA	26755581
GO:0006114	Process	Glycerol biosynthetic process	IEA
GO:0006650	Process	Glycerophospholipid metabolic process	IDA	26755581
GO:0006650	Process	Glycerophospholipid metabolic process	IEA
GO:0008967	Function	Phosphoglycolate phosphatase activity	IDA	26755581
GO:0016787	Function	Hydrolase activity	IEA
GO:0016791	Function	Phosphatase activity	IEA
GO:0043136	Function	Sn-glycerol 3-phosphatase activity	IBA
GO:0043136	Function	Sn-glycerol 3-phosphatase activity	IDA	26755581
GO:0043136	Function	Sn-glycerol 3-phosphatase activity	IEA
GO:0043262	Function	ADP phosphatase activity	IEA
GO:0045721	Process	Negative regulation of gluconeogenesis	IMP	26755581
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
172280	8909	ENSG00000184207

Protein

UniProt ID

A6NDG6

Protein name

Glycerol-3-phosphate phosphatase (G3PP) (EC 3.1.3.21) (Aspartate-based ubiquitous Mg(2+)-dependent phosphatase) (AUM) (EC 3.1.3.48) (Phosphoglycolate phosphatase) (PGP)

Protein function

Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphog

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13344	Hydrolase_6	31 → 139	Haloacid dehalogenase-like hydrolase	Domain
PF13242	Hydrolase_like	232 → 315		Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in all tissues including red cells, lymphocytes and cultured fibroblasts (at protein level). The highest activities occur in skeletal muscle and cardiac muscle. {ECO:0000269|PubMed:215071}.

Sequence

MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARG
KRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPK
AYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMK
LTKALRYLQQPGCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFI
FDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSK
KKMVPDFYVDSIADLLPALQG

Sequence length

321

Interactions

View interactions

	KEGG
	Glyoxylate and dicarboxylate metabolism Metabolic pathways Carbon metabolism

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Atrial Fibrillation	Atrial fibrillation	N/A	N/A	GWAS

Show/Hide Text Mining Associations (99)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Achalasia Addisonianism Alacrimia syndrome	Associate	26234720
Alzheimer Disease	Inhibit	32885413, 40023574
Alzheimer Disease	Associate	33115695
Arthritis Rheumatoid	Associate	36724603
Autoimmune Diseases	Inhibit	40023574
Bacterial Infections	Associate	33427563
Breast Neoplasms	Associate	16925584, 17912240, 19940361, 22521303, 22615870, 24368600, 25973019, 26279432, 26722437, 28131717, 30292104, 35449387, 40332431
Breast Neoplasms	Stimulate	36867605, 9180147
Calcinosis Cutis	Associate	28131717
Cancer Pain	Associate	19079610
Carcinogenesis	Associate	10562814, 22751348
Carcinoma Hepatocellular	Associate	25310259, 25493932, 31976328, 35426328, 36071480, 7587708
Carcinoma Non Small Cell Lung	Associate	19031941, 31952518
Carcinoma Ovarian Epithelial	Associate	19079610
Carcinoma Renal Cell	Associate	19393132, 19552816
Carcinoma Squamous Cell	Associate	17912240, 31952518
Colorectal Neoplasms	Associate	23608383, 27409663, 28217977, 32203206, 8098614, 9330605
Cystic Fibrosis	Associate	15964250
Diabetic Neuropathies	Inhibit	23685187
Disease Resistance	Associate	28656316
Disease Resistance	Stimulate	28864784
Drug Hypersensitivity	Associate	16651436
Drug Related Side Effects and Adverse Reactions	Stimulate	11850258
Drug Related Side Effects and Adverse Reactions	Associate	19549303, 31181726, 9029024, 9716379
Drug Resistant Epilepsy	Associate	24669930, 28587680, 9516147
Edema	Associate	23685187
Endometrial Neoplasms	Associate	1707232
Esophageal Squamous Cell Carcinoma	Associate	20193114
Gastritis	Associate	22751348
GATA2 Deficiency	Associate	9885221
Glioblastoma	Associate	19288188
Glioma	Associate	23637844
Hepatolenticular Degeneration	Associate	34117631
Hereditary Breast and Ovarian Cancer Syndrome	Associate	10604726
HIV Infections	Associate	26902756
Hypesthesia	Associate	16906282
Hypoxia	Stimulate	21595915, 33326735
Hypoxia Brain	Associate	21595915
Infections	Associate	33427563, 36721242
Inflammation	Associate	22001987, 31101589, 37834286
Intestinal Diseases	Associate	22751348, 23328208
Klatskin Tumor	Associate	15655831
Leukemia	Associate	18200595, 24454800, 31195716, 7587708, 8639853
Leukemia Biphenotypic Acute	Associate	9450804
Leukemia Large Granular Lymphocytic	Associate	9885221
Leukemia Lymphocytic Chronic B Cell	Associate	17085864, 19635183
Leukemia Lymphoma Adult T Cell	Associate	9516147
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	21418741, 22098951, 23891189, 35887063
Leukemia Myeloid Acute	Associate	10419897, 10779437, 18200595, 24615181, 32426817, 9886324
Leukemia Promyelocytic Acute	Associate	15108169
Liver Neoplasms	Associate	24676670
Lung Diseases	Associate	29678179
Lung Neoplasms	Associate	26182353, 9669397
Lupus Erythematosus Systemic	Associate	18820766
Lupus Erythematosus Systemic	Inhibit	40023574
Lymphoma	Associate	22833464, 7632959
Lymphoma T Cell Peripheral	Associate	22833464
Medium chain acyl CoA dehydrogenase deficiency	Associate	37298607
Melanoma	Associate	38226983
Mohr Tranebjaerg syndrome	Stimulate	32400857
Multiple Myeloma	Associate	7507731
Multiple Myeloma	Inhibit	9345062
Nasopharyngeal Carcinoma	Associate	32400857
Neoplasm Metastasis	Associate	20234362
Neoplasms	Associate	11823484, 11850258, 15112342, 15548804, 16382213, 16651436, 1707232, 17912240, 18945821, 19288188, 19548831, 20193114, 20811323, 20957096, 21418741 View all (23 more)
Neoplasms	Inhibit	32523334
Neuroblastoma	Associate	20072950
Neuropathy Painful	Associate	23666525
Neutropenia	Associate	22833464
Osteosarcoma	Associate	30430199, 35201621
Ototoxicity	Associate	37768946
Ovarian Neoplasms	Associate	10604726, 40158757
Pain	Associate	23685187
Pancreatic Neoplasms	Associate	11854916, 17695494, 20684793
Polycystic Kidney Diseases	Associate	2821260, 3008903
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	11849207, 23280566, 8639853
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	10444168, 15384974, 23326330, 9450804
Prostatic Intraepithelial Neoplasia	Inhibit	24344919
Prostatitis	Associate	24344919
Retinoblastoma	Associate	15548804
Rhabdomyosarcoma	Associate	20072950
Sarcoma	Associate	22662203, 32316291, 34069490, 35328603
Sarcoma Ewing	Associate	23799853
Sarcoma Synovial	Associate	22662203, 35328603
Sleep Apnea Obstructive	Stimulate	32647186
Small Cell Lung Carcinoma	Associate	8980384
Squamous Intraepithelial Lesions	Associate	23464400
Stomach Neoplasms	Associate	12616123, 15771954, 18296917, 22751348, 24377601, 25407491, 30551491
Tertiary Lymphoid Structures	Associate	16168133
Thyroid Cancer Papillary	Associate	30904818
Tremor	Associate	15886424
Triple Negative Breast Neoplasms	Associate	40724925
Tuberculosis Meningeal	Associate	37834286
Tuberculosis Multidrug Resistant	Associate	10050716, 10354131, 10562814, 11278745, 15655831, 16651436, 1707232, 17912240, 18296917, 19548831, 19582433, 21905209, 22245869, 22320957, 22662203 View all (29 more)
Tuberculosis Multidrug Resistant	Stimulate	18200595, 24805866, 40158757
Urethral Neoplasms	Associate	35610207
Uterine Cervical Neoplasms	Associate	22245869
Uterine Cervicitis	Associate	23464400
Virus Diseases	Associate	33427563

PGP (phosphoglycolate phosphatase)