CD163L1 (CD163 molecule like 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
283316
Gene name Gene Name - the full gene name approved by the HGNC.
CD163 molecule like 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CD163L1
Synonyms (NCBI Gene) Gene synonyms aliases
CD163B, M160, SCARI2, STAR, WC1
Disease Acronyms (UniProt) Disease acronyms from UniProt database
STAR
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12p13.31
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. The SRCR family is defined by a 100-110 amino
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(12)
miRTarBase ID miRNA Experiments Reference
MIRT040498 hsa-miR-590-5p CLASH 23622248
MIRT440978 hsa-miR-218-5p HITS-CLIP 23212916
MIRT440978 hsa-miR-218-5p HITS-CLIP 23212916
MIRT1959187 hsa-miR-1226 CLIP-seq
MIRT1959188 hsa-miR-132 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0005044 Function Scavenger receptor activity IEA
GO:0005576 Component Extracellular region IEA
GO:0006897 Process Endocytosis IEA
GO:0009897 Component External side of plasma membrane IBA 21873635
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
606079 30375 ENSG00000177675
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q9NR16
Protein name Scavenger receptor cysteine-rich type 1 protein M160 (CD163 antigen-like 1) (CD antigen CD163b)
PDB 6K0O
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00530 SRCR 51 → 148 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 158 → 255 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 265 → 362 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 372 → 469 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 479 → 576 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 586 → 683 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 693 → 790 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 798 → 895 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 903 → 1000 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 1039 → 1136 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 1146 → 1243 Scavenger receptor cysteine-rich domain Domain
PF00530 SRCR 1249 → 1346 Scavenger receptor cysteine-rich domain Domain
Tissue specificity TISSUE SPECIFICITY: Isoform 1 is highly expressed in the spleen, lymph nodes, thymus, and fetal liver and weakly expressed in bone marrow and no expression was found in peripheral blood leukocytes. Isoform 1 expression is restricted to the monocyte and ma
Sequence 
MMLPQNSWHIDFGRCCCHQNLFSAVVTCILLLNSCFLISSFNGTDLELRLVNGDGPCSGT
VEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDVSCYGN
ESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCSGRVEVKFQERWGTIC
DDGWNLNTAAVVCRQLGCPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWG
NHDCSHNEDVTLTCYDSSDLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVC
KQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVI
CSDGADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSR
RAKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGVICSDKADLDLRLVG
AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPLHVFGMTYFKEASGPIWL
DDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLRLVGGSNRCSGRLEVYF
QGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCDGDESDLW
SCRNSGWGNNDCSHSEDVGVICSDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWG
MNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACH
LNMEASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGD
AISLSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCSRYTDV
RLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSV
RVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLS
AVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCG
VAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTA
LRLYSETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKT
GSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITCEDRIRVRGGDTECSGRVE
IWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNES
FLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASSGHLALILSSIFGLLLLVLFILFL
TWCRVQKQKHLPLRVSTRRRGSLEENLFHEMETCLKREDPHGTRTSDDTPNHGCEDASDT
SLLGVLPASEATK
Sequence length 1453
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (2)
Causal
Disease term Disease name dbSNP ID References
Intracranial aneurysm Intracranial Aneurysm rs1594095223 30823506
Melanoma melanoma rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340
View all (64 more)		 22842228
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Intracranial Aneurysm Intracranial Aneurysm GWAS
Glioblastoma Glioblastoma CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 GWAS, CBGDA
Show/Hide Text Mining Associations (2)
Associations from Text Mining
Disease Name Relationship Type References
Neoplasms Associate 27401919
Neoplasms Inhibit 39202452