Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	2769
Gene name	G protein subunit alpha 15
Gene symbol	GNA15
Synonyms (NCBI Gene)	GNA16HG1L
Chromosome	19
Chromosome location	19p13.3

Show/Hide all (21)

miRTarBase ID	miRNA	Experiments
MIRT1023153	hsa-miR-1184	CLIP-seq
MIRT1023154	hsa-miR-3117-5p	CLIP-seq
MIRT1023155	hsa-miR-4691-3p	CLIP-seq
MIRT1023156	hsa-miR-4704-5p	CLIP-seq
MIRT1023157	hsa-miR-615-5p	CLIP-seq
MIRT2003432	hsa-miR-3173-3p	CLIP-seq
MIRT2003433	hsa-miR-4265	CLIP-seq
MIRT2003434	hsa-miR-4296	CLIP-seq
MIRT2003435	hsa-miR-4322	CLIP-seq
MIRT2003436	hsa-miR-4417	CLIP-seq
MIRT2003437	hsa-miR-4645-3p	CLIP-seq
MIRT2003438	hsa-miR-4738-3p	CLIP-seq
MIRT2003439	hsa-miR-4779	CLIP-seq
MIRT2003440	hsa-miR-542-3p	CLIP-seq
MIRT2236283	hsa-miR-1197	CLIP-seq
MIRT2236284	hsa-miR-1286	CLIP-seq
MIRT2236285	hsa-miR-3180-5p	CLIP-seq
MIRT2236286	hsa-miR-4436a	CLIP-seq
MIRT2003437	hsa-miR-4645-3p	CLIP-seq
MIRT2236287	hsa-miR-4738-5p	CLIP-seq
MIRT2003440	hsa-miR-542-3p	CLIP-seq

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0001664	Function	G protein-coupled receptor binding	IDA	10571060
GO:0001664	Function	G protein-coupled receptor binding	IEA
GO:0003924	Function	GTPase activity	IEA
GO:0003924	Function	GTPase activity	TAS	7797501
GO:0005525	Function	GTP binding	IEA
GO:0005525	Function	GTP binding	TAS
GO:0005834	Component	Heterotrimeric G-protein complex	NAS	10571060
GO:0005886	Component	Plasma membrane	TAS	7797501, 8415674
GO:0007165	Process	Signal transduction	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007200	Process	Phospholipase C-activating G protein-coupled receptor signaling pathway	IEA
GO:0007207	Process	Phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	TAS	7797501
GO:0019001	Function	Guanyl nucleotide binding	IEA
GO:0019722	Process	Calcium-mediated signaling	IEA
GO:0019722	Process	Calcium-mediated signaling	IPI	10571060
GO:0031683	Function	G-protein beta/gamma-subunit complex binding	IEA
GO:0045202	Component	Synapse	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
139314	4383	ENSG00000060558

P30679

Protein name

Guanine nucleotide-binding protein subunit alpha-15 (G alpha-15) (G-protein subunit alpha-15) (Epididymis tissue protein Li 17E) (Guanine nucleotide-binding protein subunit alpha-16) (G alpha-16) (G-protein subunit alpha-16)

Protein function

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00503	G-alpha	22 → 363	G-protein alpha subunit	Domain

Tissue specificity

TISSUE SPECIFICITY: Specifically expressed in hematopoietic cells. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409}.

Sequence

MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
PYKVTTFEKRYAAAMQWLWRDAGIRAYYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
DSVLARYLDEINLL

Sequence length

374

Interactions

View interactions

	KEGG		Reactome
	Calcium signaling pathway Hormone signaling Relaxin signaling pathway Chagas disease Amoebiasis		Acetylcholine regulates insulin secretion G alpha (q) signalling events ADP signalling through P2Y purinoceptor 1 Thromboxane signalling through TP receptor Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Thrombin signalling through proteinase activated receptors (PARs)

GNA15 (G protein subunit alpha 15)