Gene Gene information from NCBI Gene database.
Entrez ID 27346
Gene name Transmembrane protein 97
Gene symbol TMEM97
Synonyms (NCBI Gene)
MAC30S2Rsigma2R
Chromosome 17
Chromosome location 17q11.2
Summary TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009 [PubMed 19583955]).[supplied by OMIM, Aug 2009]
miRNA miRNA information provided by mirtarbase database.
793
miRTarBase ID miRNA Experiments Reference
MIRT025807 hsa-miR-7-5p Microarray 17612493
MIRT025807 hsa-miR-7-5p Microarray 19073608
MIRT050502 hsa-miR-20a-5p CLASH 23622248
MIRT041579 hsa-miR-193b-3p CLASH 23622248
MIRT039218 hsa-miR-769-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
GO ID Ontology Definition Evidence Reference
GO:0001558 Process Regulation of cell growth NAS 7694637
GO:0005515 Function Protein binding IPI 19583955, 30443021, 32296183, 34233061, 34799735, 37047353
GO:0005634 Component Nucleus IEA
GO:0005764 Component Lysosome IDA 19583955
GO:0005783 Component Endoplasmic reticulum IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612912 28106 ENSG00000109084
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5BJF2
Protein name Sigma intracellular receptor 2 (S2R) (Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (MAC30) (Transmembrane protein 97)
Protein function Sigma-2 receptor which contributes to ameliorate dysfunctional cellular processes and slow degenerative progression by regulating cell functions including cholesterol biosynthesis/trafficking, membrane trafficking, autophagy, lipid membrane-boun
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05241 EBP 43 161 Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells. Highly expressed in various proliferating cancer cells (PubMed:23922215). {ECO:0000269|PubMed:15375745, ECO:0000
Sequence
Sequence length 176
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Neuroactive ligand-receptor interaction