TMEM97 (transmembrane protein 97)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
27346 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Transmembrane protein 97 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
TMEM97 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
MAC30, S2R, sigma2R |
Chromosome
Chromosome number
|
17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
17q11.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009 [PubMed 19583955]).[supplied by OMIM, Aug 2009] |
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | |||||||||||
UniProt ID | Q5BJF2 | ||||||||||
Protein name | Sigma intracellular receptor 2 (S2R) (Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (MAC30) (Transmembrane protein 97) | ||||||||||
Protein function | Sigma-2 receptor which contributes to ameliorate dysfunctional cellular processes and slow degenerative progression by regulating cell functions including cholesterol biosynthesis/trafficking, membrane trafficking, autophagy, lipid membrane-boun | ||||||||||
Family and domains |
Pfam
|
||||||||||
Tissue specificity | TISSUE SPECIFICITY: Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells. Highly expressed in various proliferating cancer cells (PubMed:23922215). {ECO:0000269|PubMed:15375745, ECO:0000 | ||||||||||
Sequence |
|
||||||||||
Sequence length | 176 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
||||||||
|
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|