PDE7B (phosphodiesterase 7B)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 27115 |
| Gene name | Phosphodiesterase 7B |
| Gene symbol | PDE7B |
| Synonyms (NCBI Gene) |
bA472E5.1
|
| Chromosome | 6 |
| Chromosome location | 6q23.3 |
| Summary | The 3`,5`-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3`,5`-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5`-monophosphates a |
|
miRNA
miRNA information provided by mirtarbase database.
537
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
|||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
Q9NP56 | ||||||||||
| Protein name | 3',5'-cyclic-AMP phosphodiesterase 7B (EC 3.1.4.53) (cAMP-specific phosphodiesterase 7B) | ||||||||||
| Protein function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10814504, PubMed:10872825). May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (PubMed | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in brain (PubMed:10814504). Also expressed in heart, liver, skeletal muscle and pancreas (PubMed:10814504). {ECO:0000269|PubMed:10814504}. | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 450 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||||
|
|||||||||
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||