PDE7B (phosphodiesterase 7B)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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27115 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Phosphodiesterase 7B |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PDE7B |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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bA472E5.1 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q23.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The 3`,5`-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3`,5`-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5`-monophosphates a |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9NP56 | ||||||||||
| Protein name | 3',5'-cyclic-AMP phosphodiesterase 7B (EC 3.1.4.53) (cAMP-specific phosphodiesterase 7B) | ||||||||||
| Protein function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:10814504, PubMed:10872825). May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain (PubMed | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in brain (PubMed:10814504). Also expressed in heart, liver, skeletal muscle and pancreas (PubMed:10814504). {ECO:0000269|PubMed:10814504}. | ||||||||||
| Sequence |
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| Sequence length | 450 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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