NPTN (neuroplastin)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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27020 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Neuroplastin |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NPTN |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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GP55, GP65, SDFR1, SDR1, np55, np65 |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q24.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by R |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||
| UniProt ID | Q9Y639 | ||||||||||||||||||||
| Protein name | Neuroplastin (Stromal cell-derived receptor 1) (SDR-1) | ||||||||||||||||||||
| Protein function | Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May p | ||||||||||||||||||||
| PDB | 6A69 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level). {ECO:0000269|PubMed:17196182, ECO:0000269|Ref.1}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 398 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||