Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
27020
Gene name Gene Name - the full gene name approved by the HGNC.
Neuroplastin
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NPTN
Synonyms (NCBI Gene) Gene synonyms aliases
GP55, GP65, SDFR1, SDR1, np55, np65
Chromosome Chromosome number
15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q24.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by R
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT023641 hsa-miR-1-3p Proteomics 18668040
MIRT029137 hsa-miR-26b-5p Microarray 19088304
MIRT051931 hsa-let-7b-5p CLASH 23622248
MIRT046088 hsa-miR-125b-5p CLASH 23622248
MIRT037907 hsa-miR-455-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001772 Component Immunological synapse IEA
GO:0001772 Component Immunological synapse ISS
GO:0001818 Process Negative regulation of cytokine production IEA
GO:0001818 Process Negative regulation of cytokine production ISS
GO:0001934 Process Positive regulation of protein phosphorylation ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
612820 17867 ENSG00000156642
Protein
UniProt ID Q9Y639
Protein name Neuroplastin (Stromal cell-derived receptor 1) (SDR-1)
Protein function Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May p
PDB 6A69
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13927 Ig_3 33 120 Domain
PF13927 Ig_3 147 221 Domain
PF13927 Ig_3 237 320 Domain
Tissue specificity TISSUE SPECIFICITY: Isoform 1 is ubiquitously expressed. Isoform 2 is expressed in brain cortex and cerebellum (at protein level). {ECO:0000269|PubMed:17196182, ECO:0000269|Ref.1}.
Sequence
Sequence length 398
Interactions View interactions
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