Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2674
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
GDNF family receptor alpha 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
GFRA1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
GDNFR, GDNFR-alpha-1, GDNFRA, GFR-ALPHA-1, GFRalpha-1, RET1L, RETL1, RHDA4, TRNR1 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
RHDA4 |
Chromosome
Chromosome number
|
10 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
10q25.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) a |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Hirschsprung disease |
Hirschsprung Disease |
rs76262710, rs75996173, rs77316810, rs75076352, rs76534745, rs76764689, rs76449634, rs377767412, rs193922699, rs75030001, rs606231342, rs1553540620, rs759944122, rs1057519322, rs1057519323, rs1057519052, rs1588873476, rs1588866040, rs1838178869 View all (4 more) |
19196962 |
Rheumatoid arthritis |
Rheumatoid Arthritis |
rs587776843 |
26776603 |
Schizophrenia |
Schizophrenia |
rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 View all (12 more) |
20116071 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
RENAL HYPODYSPLASIA/APLASIA |
renal hypodysplasia/aplasia 4 |
|
|
GenCC |
Huntington Disease |
Huntington Disease |
|
|
GWAS |
Uveal Melanoma |
Uveal Melanoma |
Furthermore, knocking-down GPS2 promoted the proliferation and metastatic abilities of UM cells both in vivo and in vitro. |
|
GWAS, CBGDA |
Migraine with Aura |
Migraine with Aura |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Adenocarcinoma |
Associate
|
26867769 |
Alzheimer Disease |
Associate
|
25253858 |
Brain Neoplasms |
Associate
|
10408842 |
Breast Neoplasms |
Stimulate
|
23351331 |
Breast Neoplasms |
Associate
|
23650283, 24641868, 33838601 |
Cakut |
Associate
|
22729463, 36292572 |
Carcinoma Adenoid Cystic |
Associate
|
33628594 |
Carcinoma Hepatocellular |
Associate
|
31545220, 33215421 |
Colorectal Neoplasms |
Associate
|
27566576 |
Diabetes Gestational |
Associate
|
35721735 |
Diverticular Diseases |
Inhibit
|
28152033 |
Diverticulum |
Inhibit
|
28152033 |
Gingival Diseases |
Associate
|
31743516 |
Glioblastoma |
Associate
|
26156397 |
Hereditary renal agenesis |
Associate
|
33020172, 36292572 |
Hirschsprung Disease |
Associate
|
12065680, 20459765, 33020172 |
Leukemia |
Associate
|
9108413 |
Leukemia Myeloid Acute |
Associate
|
33219204 |
Migraine Disorders |
Associate
|
31842742 |
Myelodysplastic Syndromes |
Associate
|
33219204 |
Neoplasm Metastasis |
Associate
|
25009298, 31431673, 36808605 |
Neoplasms |
Associate
|
10408842, 23544068, 33838601, 36808605 |
Nerve Degeneration |
Associate
|
25253858 |
Neuroblastoma |
Associate
|
17388787 |
Osteosarcoma |
Associate
|
32841458 |
Pancreatic Neoplasms |
Associate
|
24895587, 32438692 |
Peripheral Nervous System Diseases |
Associate
|
30648113 |
Prostatic Neoplasms |
Associate
|
25575823, 35832649 |
Rectal Neoplasms |
Associate
|
27566576 |
Stomach Neoplasms |
Associate
|
25009298, 36808605 |
Tarlov Cysts |
Associate
|
33628594 |
Thyroid cancer medullary |
Associate
|
23201134 |
Thyroid Cancer Papillary |
Associate
|
19138047 |
Thyroid Nodule |
Associate
|
19138047 |
Venous Thromboembolism |
Associate
|
21463476 |
|