Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	267004
Gene name Gene Name - the full gene name approved by the HGNC.	PiggyBac transposable element derived 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PGBD3
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q11.23
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of a small family of genes derived from piggyBac transposable elements. The encoded protein contains a zinc-ribbon domain characteristic of transposon-derived proteins and may function as a regulator of transcription. Alternative spl

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miRTarBase ID	miRNA	Experiments
MIRT1227214	hsa-miR-129-5p	CLIP-seq
MIRT1227215	hsa-miR-221	CLIP-seq
MIRT1227216	hsa-miR-222	CLIP-seq
MIRT1227217	hsa-miR-3163	CLIP-seq
MIRT1227218	hsa-miR-4282	CLIP-seq
MIRT1227219	hsa-miR-4307	CLIP-seq
MIRT1227220	hsa-miR-4452	CLIP-seq
MIRT1227221	hsa-miR-450b-5p	CLIP-seq
MIRT1227222	hsa-miR-4704-5p	CLIP-seq
MIRT1227223	hsa-miR-4709-3p	CLIP-seq
MIRT1227224	hsa-miR-507	CLIP-seq
MIRT1227225	hsa-miR-548a-3p	CLIP-seq
MIRT1227226	hsa-miR-548aa	CLIP-seq
MIRT1227227	hsa-miR-548e	CLIP-seq
MIRT1227228	hsa-miR-548f	CLIP-seq
MIRT1227229	hsa-miR-548v	CLIP-seq
MIRT1227230	hsa-miR-557	CLIP-seq
MIRT1227231	hsa-miR-568	CLIP-seq
MIRT1227215	hsa-miR-221	CLIP-seq
MIRT1227216	hsa-miR-222	CLIP-seq
MIRT1227226	hsa-miR-548aa	CLIP-seq
MIRT1227229	hsa-miR-548v	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005654	Component	Nucleoplasm	IDA
GO:0016604	Component	Nuclear body	IDA
GO:0043565	Function	Sequence-specific DNA binding	IBA	21873635
GO:0043565	Function	Sequence-specific DNA binding	IDA	22483866

MIM	HGNC	e!Ensembl
HGNC	19400	N/A

Protein

UniProt ID

Q8N328

Protein name

PiggyBac transposable element-derived protein 3

Protein function

Binds in vitro to PGBD3-related transposable elements, called MER85s; these non-autonomous 140 bp elements are characterized by the presence of PGBD3 terminal inverted repeats and the absence of internal transposase ORF. {ECO:0000269|PubMed:2248

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13843	DDE_Tnp_1_7	141 → 499	Transposase IS4	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart and oocytes, but not in granulosa cells (at protein level). {ECO:0000269|PubMed:26218421}.

Sequence

MPRTLSLHEITDLLETDDSIEASAIVIQPPENATAPVSDEESGDEEGGTINNLPGSLLHT
AAYLIQDGSDAESDSDDPSYAPKDDSPDEVPSTFTVQQPPPSRRRKMTKILCKWKKADLT
VQPVAGRVTAPPNDFFTVMRTPTEILELFLDDEVIELIVKYSNLYACSKGVHLGLTSSEF
KCFLGIIFLSGYVSVPRRRMFWEQRTDVHNVLVSAAMRRDRFETIFSNLHVADNANLDPV
DKFSKLRPLISKLNERCMKFVPNETYFSFDEFMVPYFGRHGCKQFIRGKPIRFGYKFWCG
ATCLGYICWFQPYQGKNPNTKHEEYGVGASLVLQFSEALTEAHPGQYHFVFNNFFTSIAL
LDKLSSMGHQATGTVRKDHIDRVPLESDVALKKKERGTFDYRIDGKGNIVCRWNDNSVVT
VASSGAGIHPLCLVSRYSQKLKKKIQVQQPNMIKVYNQFMGGVDRADENIDKYRASIRGK
KWYSSPLLFCFELVLQNAWQLHKTYDEKPVDFLEFRRRVVCHYLETHGHPPEPGQKGRPQ
KRNIDSRYDGINHVIVKQGKQTRCAECHKNTTFRCEKCDVALHVKCSVEYHTE

Sequence length

593

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Cockayne Syndrome	Associate	22483866
Primary Ovarian Insufficiency	Associate	26218421
UV Sensitive Syndrome	Associate	22483866

PGBD3 (piggyBac transposable element derived 3)