MDGA1 (MAM domain containing glycosylphosphatidylinositol anchor 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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266727 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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MAM domain containing glycosylphosphatidylinositol anchor 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MDGA1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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GPIM, MAMDC3 |
Chromosome
Chromosome number
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6 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein that is expressed predominantly in the developing nervous system. In addition to possessing several cell adhesion molecule-like domains, the mature protein has six I |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||||||||||||||||||||||
UniProt ID | Q8NFP4 | ||||||||||||||||||||||||||||||||||||||||
Protein name | MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (GPI and MAM protein) (GPIM) (Glycosylphosphatidylinositol-MAM) (MAM domain-containing protein 3) | ||||||||||||||||||||||||||||||||||||||||
Protein function | Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2. {ECO:0000250, ECO | ||||||||||||||||||||||||||||||||||||||||
PDB | 5V5V , 5V5W , 5XEQ | ||||||||||||||||||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues. | ||||||||||||||||||||||||||||||||||||||||
Sequence |
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Sequence length | 955 | ||||||||||||||||||||||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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