EHF (ETS homologous factor)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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26298 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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ETS homologous factor |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EHF |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ESE3, ESE3B, ESEJ |
Chromosome
Chromosome number
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11 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11p13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcino |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q9NZC4 | |||||||||||||||
Protein name | ETS homologous factor (hEHF) (ETS domain-containing transcription factor) (Epithelium-specific Ets transcription factor 3) (ESE-3) | |||||||||||||||
Protein function | Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activ | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, prostate, and lung. Weakly expressed in kidney and colon. Not detected in heart, brain, placenta, liver, skele | |||||||||||||||
Sequence |
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Sequence length | 300 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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