Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	26292
Gene name Gene Name - the full gene name approved by the HGNC.	MYC binding protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MYCBP
Synonyms (NCBI Gene) Gene synonyms aliases	AMY-1
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p34.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus d

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miRTarBase ID	miRNA	Experiments	Reference
MIRT005505	hsa-miR-22-3p	Immunoblot, Luciferase reporter assay, qRT-PCR	20562918
MIRT005505	hsa-miR-22-3p	Immunoblot, Luciferase reporter assay, qRT-PCR	20562918
MIRT023295	hsa-miR-122-5p	Microarray	17612493
MIRT028305	hsa-miR-32-5p	Sequencing	20371350
MIRT032374	hsa-let-7b-5p	Proteomics	18668040
MIRT038801	hsa-miR-93-3p	CLASH	23622248
MIRT674407	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT674406	hsa-miR-5693	HITS-CLIP	23824327
MIRT674405	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT674404	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT674403	hsa-miR-4770	HITS-CLIP	23824327
MIRT674402	hsa-miR-6088	HITS-CLIP	23824327
MIRT674401	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT674400	hsa-miR-1273f	HITS-CLIP	23824327
MIRT674399	hsa-miR-4534	HITS-CLIP	23824327
MIRT674398	hsa-miR-8082	HITS-CLIP	23824327
MIRT674397	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT674396	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT674395	hsa-miR-3135b	HITS-CLIP	23824327
MIRT674394	hsa-miR-1289	HITS-CLIP	23824327
MIRT674393	hsa-miR-4294	HITS-CLIP	23824327
MIRT674392	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT023295	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT674391	hsa-miR-4634	HITS-CLIP	23824327
MIRT674390	hsa-miR-3652	HITS-CLIP	23824327
MIRT674389	hsa-miR-4430	HITS-CLIP	23824327
MIRT674388	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT674387	hsa-miR-3198	HITS-CLIP	23824327
MIRT674386	hsa-miR-4309	HITS-CLIP	23824327
MIRT674385	hsa-miR-5698	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT630403	hsa-miR-4521	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT630403	hsa-miR-4521	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT472691	hsa-miR-4797-5p	PAR-CLIP	21572407
MIRT472690	hsa-miR-759	PAR-CLIP	21572407
MIRT472689	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT472688	hsa-miR-3689a-5p	PAR-CLIP	21572407
MIRT472687	hsa-miR-3689b-5p	PAR-CLIP	21572407
MIRT472686	hsa-miR-3689e	PAR-CLIP	21572407
MIRT472685	hsa-miR-3689f	PAR-CLIP	21572407
MIRT472683	hsa-miR-6800-5p	PAR-CLIP	21572407
MIRT472684	hsa-miR-183-3p	PAR-CLIP	21572407
MIRT472682	hsa-miR-302c-5p	PAR-CLIP	21572407
MIRT472681	hsa-miR-552-5p	PAR-CLIP	21572407
MIRT472691	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT472690	hsa-miR-759	PAR-CLIP	23592263
MIRT472689	hsa-miR-574-5p	PAR-CLIP	23592263
MIRT472688	hsa-miR-3689a-5p	PAR-CLIP	23592263
MIRT472687	hsa-miR-3689b-5p	PAR-CLIP	23592263
MIRT472686	hsa-miR-3689e	PAR-CLIP	23592263
MIRT472685	hsa-miR-3689f	PAR-CLIP	23592263
MIRT472683	hsa-miR-6800-5p	PAR-CLIP	23592263
MIRT472684	hsa-miR-183-3p	PAR-CLIP	23592263
MIRT472682	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT472681	hsa-miR-552-5p	PAR-CLIP	23592263
MIRT674407	hsa-miR-6514-5p	HITS-CLIP	23824327
MIRT674406	hsa-miR-5693	HITS-CLIP	23824327
MIRT674405	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT674404	hsa-miR-143-3p	HITS-CLIP	23824327
MIRT674403	hsa-miR-4770	HITS-CLIP	23824327
MIRT674402	hsa-miR-6088	HITS-CLIP	23824327
MIRT674401	hsa-miR-4708-5p	HITS-CLIP	23824327
MIRT674400	hsa-miR-1273f	HITS-CLIP	23824327
MIRT674399	hsa-miR-4534	HITS-CLIP	23824327
MIRT674398	hsa-miR-8082	HITS-CLIP	23824327
MIRT674397	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT674396	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT674395	hsa-miR-3135b	HITS-CLIP	23824327
MIRT674394	hsa-miR-1289	HITS-CLIP	23824327
MIRT674393	hsa-miR-4294	HITS-CLIP	23824327
MIRT674392	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT023295	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT674391	hsa-miR-4634	HITS-CLIP	23824327
MIRT674390	hsa-miR-3652	HITS-CLIP	23824327
MIRT674389	hsa-miR-4430	HITS-CLIP	23824327
MIRT674388	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT674387	hsa-miR-3198	HITS-CLIP	23824327
MIRT674386	hsa-miR-4309	HITS-CLIP	23824327
MIRT674385	hsa-miR-5698	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT630403	hsa-miR-4521	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT630403	hsa-miR-4521	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT609941	hsa-miR-8485	HITS-CLIP	23824327
MIRT609940	hsa-miR-101-5p	HITS-CLIP	23824327
MIRT472691	hsa-miR-4797-5p	PAR-CLIP	21572407
MIRT472690	hsa-miR-759	PAR-CLIP	21572407
MIRT472689	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT472688	hsa-miR-3689a-5p	PAR-CLIP	21572407
MIRT472687	hsa-miR-3689b-5p	PAR-CLIP	21572407
MIRT472686	hsa-miR-3689e	PAR-CLIP	21572407
MIRT472685	hsa-miR-3689f	PAR-CLIP	21572407
MIRT472683	hsa-miR-6800-5p	PAR-CLIP	21572407
MIRT472684	hsa-miR-183-3p	PAR-CLIP	21572407
MIRT472682	hsa-miR-302c-5p	PAR-CLIP	21572407
MIRT472681	hsa-miR-552-5p	PAR-CLIP	21572407
MIRT472691	hsa-miR-4797-5p	PAR-CLIP	23592263
MIRT472690	hsa-miR-759	PAR-CLIP	23592263
MIRT472689	hsa-miR-574-5p	PAR-CLIP	23592263
MIRT472688	hsa-miR-3689a-5p	PAR-CLIP	23592263
MIRT472687	hsa-miR-3689b-5p	PAR-CLIP	23592263
MIRT472686	hsa-miR-3689e	PAR-CLIP	23592263
MIRT472685	hsa-miR-3689f	PAR-CLIP	23592263
MIRT472683	hsa-miR-6800-5p	PAR-CLIP	23592263
MIRT472684	hsa-miR-183-3p	PAR-CLIP	23592263
MIRT472682	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT472681	hsa-miR-552-5p	PAR-CLIP	23592263
MIRT756212	hsa-miR-889-3p	Luciferase reporter assay, Western blotting, qRT-PCR, Immunoprecipitaion (IP), RNA pull down assay	38570856
MIRT1167752	hsa-let-7a	CLIP-seq
MIRT1167753	hsa-let-7b	CLIP-seq
MIRT1167754	hsa-let-7c	CLIP-seq
MIRT1167755	hsa-let-7d	CLIP-seq
MIRT1167756	hsa-let-7e	CLIP-seq
MIRT1167757	hsa-let-7f	CLIP-seq
MIRT1167758	hsa-let-7g	CLIP-seq
MIRT1167759	hsa-let-7i	CLIP-seq
MIRT1167760	hsa-miR-10a	CLIP-seq
MIRT1167761	hsa-miR-10b	CLIP-seq
MIRT1167762	hsa-miR-1206	CLIP-seq
MIRT1167763	hsa-miR-1244	CLIP-seq
MIRT1167764	hsa-miR-1252	CLIP-seq
MIRT1167765	hsa-miR-1284	CLIP-seq
MIRT1167766	hsa-miR-1294	CLIP-seq
MIRT1167767	hsa-miR-1297	CLIP-seq
MIRT1167768	hsa-miR-1324	CLIP-seq
MIRT1167769	hsa-miR-139-5p	CLIP-seq
MIRT1167770	hsa-miR-153	CLIP-seq
MIRT1167771	hsa-miR-186	CLIP-seq
MIRT1167772	hsa-miR-199a-5p	CLIP-seq
MIRT1167773	hsa-miR-199b-5p	CLIP-seq
MIRT1167774	hsa-miR-19a	CLIP-seq
MIRT1167775	hsa-miR-19b	CLIP-seq
MIRT1167776	hsa-miR-202	CLIP-seq
MIRT1167777	hsa-miR-216a	CLIP-seq
MIRT1167778	hsa-miR-26a	CLIP-seq
MIRT1167779	hsa-miR-26b	CLIP-seq
MIRT1167780	hsa-miR-300	CLIP-seq
MIRT1167781	hsa-miR-3130-3p	CLIP-seq
MIRT1167782	hsa-miR-3140-5p	CLIP-seq
MIRT1167783	hsa-miR-3154	CLIP-seq
MIRT1167784	hsa-miR-3545-3p	CLIP-seq
MIRT1167785	hsa-miR-361-5p	CLIP-seq
MIRT1167786	hsa-miR-365	CLIP-seq
MIRT1167787	hsa-miR-381	CLIP-seq
MIRT1167788	hsa-miR-4272	CLIP-seq
MIRT1167789	hsa-miR-4301	CLIP-seq
MIRT1167790	hsa-miR-4302	CLIP-seq
MIRT1167791	hsa-miR-4316	CLIP-seq
MIRT1167792	hsa-miR-4330	CLIP-seq
MIRT1167793	hsa-miR-4420	CLIP-seq
MIRT1167794	hsa-miR-4423-3p	CLIP-seq
MIRT1167795	hsa-miR-4458	CLIP-seq
MIRT1167796	hsa-miR-4465	CLIP-seq
MIRT1167797	hsa-miR-448	CLIP-seq
MIRT1167798	hsa-miR-4500	CLIP-seq
MIRT1167799	hsa-miR-4539	CLIP-seq
MIRT1167800	hsa-miR-4645-3p	CLIP-seq
MIRT1167801	hsa-miR-4666-3p	CLIP-seq
MIRT1167802	hsa-miR-4677-3p	CLIP-seq
MIRT1167803	hsa-miR-4753-5p	CLIP-seq
MIRT1167804	hsa-miR-4773	CLIP-seq
MIRT1167805	hsa-miR-4795-3p	CLIP-seq
MIRT1167806	hsa-miR-485-3p	CLIP-seq
MIRT1167807	hsa-miR-548aa	CLIP-seq
MIRT1167808	hsa-miR-561	CLIP-seq
MIRT1167809	hsa-miR-582-5p	CLIP-seq
MIRT1167810	hsa-miR-597	CLIP-seq
MIRT1167811	hsa-miR-648	CLIP-seq
MIRT1167812	hsa-miR-711	CLIP-seq
MIRT1167813	hsa-miR-767-5p	CLIP-seq
MIRT1167814	hsa-miR-891b	CLIP-seq
MIRT1167815	hsa-miR-943	CLIP-seq
MIRT1167816	hsa-miR-98	CLIP-seq
MIRT1167752	hsa-let-7a	CLIP-seq
MIRT1167753	hsa-let-7b	CLIP-seq
MIRT1167754	hsa-let-7c	CLIP-seq
MIRT1167755	hsa-let-7d	CLIP-seq
MIRT1167756	hsa-let-7e	CLIP-seq
MIRT1167757	hsa-let-7f	CLIP-seq
MIRT1167758	hsa-let-7g	CLIP-seq
MIRT1167759	hsa-let-7i	CLIP-seq
MIRT1167760	hsa-miR-10a	CLIP-seq
MIRT1167761	hsa-miR-10b	CLIP-seq
MIRT1167766	hsa-miR-1294	CLIP-seq
MIRT1167776	hsa-miR-202	CLIP-seq
MIRT1167791	hsa-miR-4316	CLIP-seq
MIRT1167795	hsa-miR-4458	CLIP-seq
MIRT1167798	hsa-miR-4500	CLIP-seq
MIRT1167802	hsa-miR-4677-3p	CLIP-seq
MIRT1167816	hsa-miR-98	CLIP-seq
MIRT2048404	hsa-miR-100	CLIP-seq
MIRT1167763	hsa-miR-1244	CLIP-seq
MIRT2048405	hsa-miR-1292	CLIP-seq
MIRT1167769	hsa-miR-139-5p	CLIP-seq
MIRT2048406	hsa-miR-2278	CLIP-seq
MIRT2048407	hsa-miR-27a	CLIP-seq
MIRT2048408	hsa-miR-27b	CLIP-seq
MIRT2048409	hsa-miR-298	CLIP-seq
MIRT2048410	hsa-miR-3074-3p	CLIP-seq
MIRT2048411	hsa-miR-3119	CLIP-seq
MIRT2048412	hsa-miR-3140-3p	CLIP-seq
MIRT2048413	hsa-miR-3174	CLIP-seq
MIRT2048414	hsa-miR-335	CLIP-seq
MIRT2048415	hsa-miR-3606	CLIP-seq
MIRT1167786	hsa-miR-365	CLIP-seq
MIRT2048416	hsa-miR-3678-5p	CLIP-seq
MIRT2048417	hsa-miR-377	CLIP-seq
MIRT2048418	hsa-miR-4291	CLIP-seq
MIRT2048419	hsa-miR-4328	CLIP-seq
MIRT1167793	hsa-miR-4420	CLIP-seq
MIRT2048420	hsa-miR-4422	CLIP-seq
MIRT2048421	hsa-miR-4468	CLIP-seq
MIRT2048422	hsa-miR-4471	CLIP-seq
MIRT2048423	hsa-miR-4699-5p	CLIP-seq
MIRT2048424	hsa-miR-4716-5p	CLIP-seq
MIRT2048425	hsa-miR-548c-3p	CLIP-seq
MIRT1167809	hsa-miR-582-5p	CLIP-seq
MIRT2048426	hsa-miR-889	CLIP-seq
MIRT2048427	hsa-miR-921	CLIP-seq
MIRT2048428	hsa-miR-99a	CLIP-seq
MIRT2048429	hsa-miR-99b	CLIP-seq
MIRT2048404	hsa-miR-100	CLIP-seq
MIRT2277231	hsa-miR-1236	CLIP-seq
MIRT2277232	hsa-miR-124	CLIP-seq
MIRT1167763	hsa-miR-1244	CLIP-seq
MIRT2048405	hsa-miR-1292	CLIP-seq
MIRT1167769	hsa-miR-139-5p	CLIP-seq
MIRT2277233	hsa-miR-147	CLIP-seq
MIRT2277234	hsa-miR-181a	CLIP-seq
MIRT2277235	hsa-miR-181b	CLIP-seq
MIRT2277236	hsa-miR-181c	CLIP-seq
MIRT2277237	hsa-miR-181d	CLIP-seq
MIRT1167771	hsa-miR-186	CLIP-seq
MIRT2277238	hsa-miR-1912	CLIP-seq
MIRT2277239	hsa-miR-22	CLIP-seq
MIRT2277240	hsa-miR-23a	CLIP-seq
MIRT2277241	hsa-miR-23b	CLIP-seq
MIRT2277242	hsa-miR-23c	CLIP-seq
MIRT2048410	hsa-miR-3074-3p	CLIP-seq
MIRT2277243	hsa-miR-3149	CLIP-seq
MIRT2048413	hsa-miR-3174	CLIP-seq
MIRT2048415	hsa-miR-3606	CLIP-seq
MIRT1167786	hsa-miR-365	CLIP-seq
MIRT2048416	hsa-miR-3678-5p	CLIP-seq
MIRT2277244	hsa-miR-3714	CLIP-seq
MIRT2048417	hsa-miR-377	CLIP-seq
MIRT2277245	hsa-miR-3910	CLIP-seq
MIRT2277246	hsa-miR-3925-3p	CLIP-seq
MIRT2277247	hsa-miR-4262	CLIP-seq
MIRT2277248	hsa-miR-4267	CLIP-seq
MIRT1167793	hsa-miR-4420	CLIP-seq
MIRT2048420	hsa-miR-4422	CLIP-seq
MIRT2048422	hsa-miR-4471	CLIP-seq
MIRT2277249	hsa-miR-4725-5p	CLIP-seq
MIRT2277250	hsa-miR-4762-5p	CLIP-seq
MIRT2277251	hsa-miR-4765	CLIP-seq
MIRT1167804	hsa-miR-4773	CLIP-seq
MIRT2277252	hsa-miR-504	CLIP-seq
MIRT2277253	hsa-miR-506	CLIP-seq
MIRT2277254	hsa-miR-511	CLIP-seq
MIRT2277255	hsa-miR-579	CLIP-seq
MIRT2277256	hsa-miR-581	CLIP-seq
MIRT1167809	hsa-miR-582-5p	CLIP-seq
MIRT1167810	hsa-miR-597	CLIP-seq
MIRT1167812	hsa-miR-711	CLIP-seq
MIRT2277257	hsa-miR-766	CLIP-seq
MIRT2048426	hsa-miR-889	CLIP-seq
MIRT2048427	hsa-miR-921	CLIP-seq
MIRT1167815	hsa-miR-943	CLIP-seq
MIRT2048428	hsa-miR-99a	CLIP-seq
MIRT2048429	hsa-miR-99b	CLIP-seq
MIRT2277239	hsa-miR-22	CLIP-seq
MIRT2277246	hsa-miR-3925-3p	CLIP-seq
MIRT2277248	hsa-miR-4267	CLIP-seq
MIRT2277257	hsa-miR-766	CLIP-seq
MIRT2454657	hsa-miR-4474-5p	CLIP-seq
MIRT2454658	hsa-miR-4480	CLIP-seq
MIRT2454659	hsa-miR-515-5p	CLIP-seq
MIRT2454660	hsa-miR-552	CLIP-seq
MIRT2454661	hsa-miR-764	CLIP-seq
MIRT1167786	hsa-miR-365	CLIP-seq
MIRT2576129	hsa-miR-4266	CLIP-seq
MIRT2576130	hsa-miR-4446-3p	CLIP-seq
MIRT2576131	hsa-miR-4540	CLIP-seq
MIRT2576132	hsa-miR-4641	CLIP-seq
MIRT2576133	hsa-miR-4656	CLIP-seq
MIRT2576134	hsa-miR-4695-5p	CLIP-seq
MIRT2576135	hsa-miR-4779	CLIP-seq
MIRT2576136	hsa-miR-938	CLIP-seq
MIRT2685620	hsa-miR-1273d	CLIP-seq
MIRT2685621	hsa-miR-185	CLIP-seq
MIRT2685622	hsa-miR-3123	CLIP-seq
MIRT2576129	hsa-miR-4266	CLIP-seq
MIRT2685623	hsa-miR-4306	CLIP-seq
MIRT2576131	hsa-miR-4540	CLIP-seq
MIRT2576132	hsa-miR-4641	CLIP-seq
MIRT2685624	hsa-miR-4644	CLIP-seq
MIRT2576134	hsa-miR-4695-5p	CLIP-seq
MIRT2685625	hsa-miR-4742-3p	CLIP-seq
MIRT2576135	hsa-miR-4779	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
LEF1	Activation	15979100

Show/Hide all(17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003713	Function	Transcription coactivator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	9797456
GO:0003713	Function	Transcription coactivator activity	IEA
GO:0005515	Function	Protein binding	IPI	12151104, 12223483, 12740381, 16866877, 33961781, 35271311
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	9797456
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	9797456, 12151104
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IDA
GO:0005739	Component	Mitochondrion	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	9797456
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0007283	Process	Spermatogenesis	IEP	12151104
GO:0045893	Process	Positive regulation of DNA-templated transcription	IEA

MIM	HGNC	e!Ensembl
606535	7554	ENSG00000214114

Protein

UniProt ID

Q99417

Protein name

c-Myc-binding protein (Associate of Myc 1) (AMY-1)

Protein function

May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.

PDB

2YY0

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in heart, placenta, pancreas, skeletal muscle and kidney. Also present at low levels in lung.

Sequence

MAHYKAADSKREQFRRYLEKSGVLDTLTKVLVALYEEPEKPNSALDFLKHHLGAATPENP
EIELLRLELAEMKEKYEAIVEENKKLKAKLAQYEPPQEEKRAE

Sequence length

103

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Carcinogenesis	Associate	36407085
Carcinoma Hepatocellular	Associate	31385398
Colorectal Neoplasms	Associate	31094023
COVID 19	Associate	35064006
Leukemia	Associate	36581344
Lymphoma T Cell Cutaneous	Associate	26244872
Multiple Myeloma	Associate	25330074
Neoplasms	Associate	20966545
Neoplasms	Inhibit	25330074
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	36581344
Triple Negative Breast Neoplasms	Associate	34895159

MYCBP (MYC binding protein)