LTN1 (listerin E3 ubiquitin protein ligase 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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26046 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Listerin E3 ubiquitin protein ligase 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LTN1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C21orf10, C21orf98, RNF160, ZNF294 |
Chromosome
Chromosome number
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21 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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21q21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||
UniProt ID | O94822 | |
Protein name | E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (RING-type E3 ubiquitin transferase listerin) (Zinc finger protein 294) | |
Protein function | E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:2368507 | |
PDB | 3J92 | |
Family and domains | ||
Sequence |
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Sequence length | 1766 | |
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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