TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3)

Gene

• Entrez ID: 257397
• Gene name: TGF-beta activated kinase 1 (MAP3K7) binding protein 3
• Gene symbol: TAB3
• Synonyms (NCBI Gene): MAP3K7IP3, NAP1
• Chromosome: X
• Chromosome location: Xp21.2
• Summary: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT007039	hsa-miR-23b-3p	Luciferase reporter assay	22660635
MIRT007039	hsa-miR-23b-3p	Luciferase reporter assay	22660635
MIRT007170	hsa-miR-195-5p	Luciferase reporter assay	23487264
MIRT007170	hsa-miR-195-5p	Luciferase reporter assay	23487264
MIRT053429	hsa-miR-512-5p	Microarray	23807165
MIRT053683	hsa-miR-181a-5p	Microarray	22942087
MIRT053696	hsa-miR-188-5p	Microarray	22942087
MIRT533989	hsa-miR-1199-5p	PAR-CLIP	22012620
MIRT533988	hsa-miR-6751-3p	PAR-CLIP	22012620
MIRT533987	hsa-miR-1252-5p	PAR-CLIP	22012620
MIRT533986	hsa-miR-610	PAR-CLIP	22012620
MIRT533985	hsa-miR-3653-3p	PAR-CLIP	22012620
MIRT533984	hsa-miR-4303	PAR-CLIP	22012620
MIRT495041	hsa-miR-1255b-2-3p	PAR-CLIP	23708386
MIRT495040	hsa-miR-6872-3p	PAR-CLIP	23708386
MIRT495039	hsa-miR-5581-3p	PAR-CLIP	23708386
MIRT495038	hsa-miR-192-3p	PAR-CLIP	23708386
MIRT533989	hsa-miR-1199-5p	PAR-CLIP	22012620
MIRT533988	hsa-miR-6751-3p	PAR-CLIP	22012620
MIRT533987	hsa-miR-1252-5p	PAR-CLIP	22012620
MIRT533986	hsa-miR-610	PAR-CLIP	22012620
MIRT533985	hsa-miR-3653-3p	PAR-CLIP	22012620
MIRT533984	hsa-miR-4303	PAR-CLIP	22012620
MIRT495041	hsa-miR-1255b-2-3p	PAR-CLIP	23708386
MIRT495040	hsa-miR-6872-3p	PAR-CLIP	23708386
MIRT495039	hsa-miR-5581-3p	PAR-CLIP	23708386
MIRT495038	hsa-miR-192-3p	PAR-CLIP	23708386
MIRT1408212	hsa-miR-1225-5p	CLIP-seq
MIRT1408213	hsa-miR-1257	CLIP-seq
MIRT1408214	hsa-miR-1302	CLIP-seq
MIRT1408215	hsa-miR-214	CLIP-seq
MIRT1408216	hsa-miR-2278	CLIP-seq
MIRT1408217	hsa-miR-3146	CLIP-seq
MIRT1408218	hsa-miR-3148	CLIP-seq
MIRT1408219	hsa-miR-330-3p	CLIP-seq
MIRT1408220	hsa-miR-338-5p	CLIP-seq
MIRT1408221	hsa-miR-361-5p	CLIP-seq
MIRT1408222	hsa-miR-3619-5p	CLIP-seq
MIRT1408223	hsa-miR-3908	CLIP-seq
MIRT1408224	hsa-miR-4261	CLIP-seq
MIRT1408225	hsa-miR-4282	CLIP-seq
MIRT1408226	hsa-miR-4291	CLIP-seq
MIRT1408227	hsa-miR-4298	CLIP-seq
MIRT1408228	hsa-miR-4299	CLIP-seq
MIRT1408229	hsa-miR-4305	CLIP-seq
MIRT1408230	hsa-miR-4456	CLIP-seq
MIRT1408231	hsa-miR-4477a	CLIP-seq
MIRT1408232	hsa-miR-4477b	CLIP-seq
MIRT1408233	hsa-miR-4496	CLIP-seq
MIRT1408234	hsa-miR-4504	CLIP-seq
MIRT1408235	hsa-miR-450b-3p	CLIP-seq
MIRT1408236	hsa-miR-4528	CLIP-seq
MIRT1408237	hsa-miR-4668-3p	CLIP-seq
MIRT1408238	hsa-miR-4700-3p	CLIP-seq
MIRT1408239	hsa-miR-4753-3p	CLIP-seq
MIRT1408240	hsa-miR-4760-3p	CLIP-seq
MIRT1408241	hsa-miR-4761-5p	CLIP-seq
MIRT1408242	hsa-miR-4768-5p	CLIP-seq
MIRT1408243	hsa-miR-4802-3p	CLIP-seq
MIRT1408244	hsa-miR-487a	CLIP-seq
MIRT1408245	hsa-miR-494	CLIP-seq
MIRT1408246	hsa-miR-542-3p	CLIP-seq
MIRT1408247	hsa-miR-548q	CLIP-seq
MIRT1408248	hsa-miR-549	CLIP-seq
MIRT1408249	hsa-miR-761	CLIP-seq
MIRT1408250	hsa-miR-769-3p	CLIP-seq
MIRT1408251	hsa-miR-922	CLIP-seq
MIRT2122450	hsa-miR-1246	CLIP-seq
MIRT2122451	hsa-miR-128	CLIP-seq
MIRT2122452	hsa-miR-1298	CLIP-seq
MIRT2122453	hsa-miR-1305	CLIP-seq
MIRT2122454	hsa-miR-142-5p	CLIP-seq
MIRT2122455	hsa-miR-153	CLIP-seq
MIRT2122456	hsa-miR-190	CLIP-seq
MIRT2122457	hsa-miR-190b	CLIP-seq
MIRT2122458	hsa-miR-203	CLIP-seq
MIRT2122459	hsa-miR-2053	CLIP-seq
MIRT2122460	hsa-miR-2110	CLIP-seq
MIRT2122461	hsa-miR-23a	CLIP-seq
MIRT2122462	hsa-miR-23b	CLIP-seq
MIRT2122463	hsa-miR-23c	CLIP-seq
MIRT2122464	hsa-miR-2682	CLIP-seq
MIRT2122465	hsa-miR-27a	CLIP-seq
MIRT2122466	hsa-miR-27b	CLIP-seq
MIRT2122467	hsa-miR-3140-3p	CLIP-seq
MIRT2122468	hsa-miR-3144-5p	CLIP-seq
MIRT2122469	hsa-miR-3145-3p	CLIP-seq
MIRT2122470	hsa-miR-3150a-3p	CLIP-seq
MIRT2122471	hsa-miR-3191	CLIP-seq
MIRT2122472	hsa-miR-3201	CLIP-seq
MIRT2122473	hsa-miR-320a	CLIP-seq
MIRT2122474	hsa-miR-320b	CLIP-seq
MIRT2122475	hsa-miR-320c	CLIP-seq
MIRT2122476	hsa-miR-320d	CLIP-seq
MIRT1408219	hsa-miR-330-3p	CLIP-seq
MIRT2122477	hsa-miR-340	CLIP-seq
MIRT1408221	hsa-miR-361-5p	CLIP-seq
MIRT2122478	hsa-miR-3619-3p	CLIP-seq
MIRT2122479	hsa-miR-3662	CLIP-seq
MIRT2122480	hsa-miR-3675-3p	CLIP-seq
MIRT2122481	hsa-miR-371-5p	CLIP-seq
MIRT2122482	hsa-miR-371b-5p	CLIP-seq
MIRT2122483	hsa-miR-3910	CLIP-seq
MIRT2122484	hsa-miR-3973	CLIP-seq
MIRT2122485	hsa-miR-412	CLIP-seq
MIRT2122486	hsa-miR-4260	CLIP-seq
MIRT1408225	hsa-miR-4282	CLIP-seq
MIRT1408226	hsa-miR-4291	CLIP-seq
MIRT2122487	hsa-miR-4302	CLIP-seq
MIRT2122488	hsa-miR-4307	CLIP-seq
MIRT2122489	hsa-miR-4311	CLIP-seq
MIRT2122490	hsa-miR-4429	CLIP-seq
MIRT2122491	hsa-miR-4475	CLIP-seq
MIRT1408231	hsa-miR-4477a	CLIP-seq
MIRT1408232	hsa-miR-4477b	CLIP-seq
MIRT2122492	hsa-miR-448	CLIP-seq
MIRT2122493	hsa-miR-449c	CLIP-seq
MIRT2122494	hsa-miR-4642	CLIP-seq
MIRT2122495	hsa-miR-4652-5p	CLIP-seq
MIRT2122496	hsa-miR-4717-3p	CLIP-seq
MIRT2122497	hsa-miR-4762-3p	CLIP-seq
MIRT2122498	hsa-miR-4791	CLIP-seq
MIRT2122499	hsa-miR-5096	CLIP-seq
MIRT2122500	hsa-miR-513a-5p	CLIP-seq
MIRT2122501	hsa-miR-520g	CLIP-seq
MIRT2122502	hsa-miR-520h	CLIP-seq
MIRT2122503	hsa-miR-548a-5p	CLIP-seq
MIRT2122504	hsa-miR-548ab	CLIP-seq
MIRT2122505	hsa-miR-548ak	CLIP-seq
MIRT2122506	hsa-miR-548an	CLIP-seq
MIRT2122507	hsa-miR-548b-5p	CLIP-seq
MIRT2122508	hsa-miR-548c-5p	CLIP-seq
MIRT2122509	hsa-miR-548d-5p	CLIP-seq
MIRT2122510	hsa-miR-548g	CLIP-seq
MIRT2122511	hsa-miR-548h	CLIP-seq
MIRT2122512	hsa-miR-548i	CLIP-seq
MIRT2122513	hsa-miR-548j	CLIP-seq
MIRT2122514	hsa-miR-548n	CLIP-seq
MIRT2122515	hsa-miR-548t	CLIP-seq
MIRT2122516	hsa-miR-548w	CLIP-seq
MIRT2122517	hsa-miR-548y	CLIP-seq
MIRT2122518	hsa-miR-559	CLIP-seq
MIRT2122519	hsa-miR-569	CLIP-seq
MIRT2122520	hsa-miR-574-5p	CLIP-seq
MIRT2122521	hsa-miR-591	CLIP-seq
MIRT2122522	hsa-miR-607	CLIP-seq
MIRT2122523	hsa-miR-759	CLIP-seq
MIRT2122524	hsa-miR-940	CLIP-seq
MIRT2344730	hsa-miR-101	CLIP-seq
MIRT2344731	hsa-miR-1183	CLIP-seq
MIRT2344732	hsa-miR-1197	CLIP-seq
MIRT2344733	hsa-miR-1208	CLIP-seq
MIRT2344734	hsa-miR-1231	CLIP-seq
MIRT2344735	hsa-miR-1252	CLIP-seq
MIRT2344736	hsa-miR-1264	CLIP-seq
MIRT2344737	hsa-miR-1272	CLIP-seq
MIRT2122451	hsa-miR-128	CLIP-seq
MIRT1408214	hsa-miR-1302	CLIP-seq
MIRT2344738	hsa-miR-1303	CLIP-seq
MIRT2122453	hsa-miR-1305	CLIP-seq
MIRT2122454	hsa-miR-142-5p	CLIP-seq
MIRT2344739	hsa-miR-144	CLIP-seq
MIRT2122455	hsa-miR-153	CLIP-seq
MIRT2344740	hsa-miR-181a	CLIP-seq
MIRT2344741	hsa-miR-181b	CLIP-seq
MIRT2344742	hsa-miR-181c	CLIP-seq
MIRT2344743	hsa-miR-181d	CLIP-seq
MIRT2344744	hsa-miR-183	CLIP-seq
MIRT2344745	hsa-miR-193a-3p	CLIP-seq
MIRT2344746	hsa-miR-193b	CLIP-seq
MIRT2344747	hsa-miR-1972	CLIP-seq
MIRT2344748	hsa-miR-199a-5p	CLIP-seq
MIRT2344749	hsa-miR-199b-5p	CLIP-seq
MIRT2344750	hsa-miR-200b	CLIP-seq
MIRT2344751	hsa-miR-200c	CLIP-seq
MIRT2122459	hsa-miR-2053	CLIP-seq
MIRT2122460	hsa-miR-2110	CLIP-seq
MIRT2344752	hsa-miR-2115	CLIP-seq
MIRT1408215	hsa-miR-214	CLIP-seq
MIRT2344753	hsa-miR-216a	CLIP-seq
MIRT2344754	hsa-miR-216b	CLIP-seq
MIRT2344755	hsa-miR-219-2-3p	CLIP-seq
MIRT2122461	hsa-miR-23a	CLIP-seq
MIRT2122462	hsa-miR-23b	CLIP-seq
MIRT2122463	hsa-miR-23c	CLIP-seq
MIRT2122465	hsa-miR-27a	CLIP-seq
MIRT2122466	hsa-miR-27b	CLIP-seq
MIRT2344756	hsa-miR-2964a-3p	CLIP-seq
MIRT2344757	hsa-miR-298	CLIP-seq
MIRT2344758	hsa-miR-3064-3p	CLIP-seq
MIRT2344759	hsa-miR-3121-5p	CLIP-seq
MIRT2344760	hsa-miR-3122	CLIP-seq
MIRT2344761	hsa-miR-3125	CLIP-seq
MIRT2344762	hsa-miR-3128	CLIP-seq
MIRT2122469	hsa-miR-3145-3p	CLIP-seq
MIRT1408218	hsa-miR-3148	CLIP-seq
MIRT2122470	hsa-miR-3150a-3p	CLIP-seq
MIRT2344763	hsa-miR-3152-5p	CLIP-seq
MIRT2344764	hsa-miR-3159	CLIP-seq
MIRT2344765	hsa-miR-3174	CLIP-seq
MIRT2344766	hsa-miR-3175	CLIP-seq
MIRT2344767	hsa-miR-3180-5p	CLIP-seq
MIRT2344768	hsa-miR-3192	CLIP-seq
MIRT2344769	hsa-miR-3194-3p	CLIP-seq
MIRT2122472	hsa-miR-3201	CLIP-seq
MIRT2344770	hsa-miR-326	CLIP-seq
MIRT2344771	hsa-miR-330-5p	CLIP-seq
MIRT1408220	hsa-miR-338-5p	CLIP-seq
MIRT2122477	hsa-miR-340	CLIP-seq
MIRT2344772	hsa-miR-34c-3p	CLIP-seq
MIRT1408221	hsa-miR-361-5p	CLIP-seq
MIRT1408222	hsa-miR-3619-5p	CLIP-seq
MIRT2344773	hsa-miR-365	CLIP-seq
MIRT2344774	hsa-miR-3653	CLIP-seq
MIRT2122479	hsa-miR-3662	CLIP-seq
MIRT2344775	hsa-miR-3681	CLIP-seq
MIRT2344776	hsa-miR-3689a-3p	CLIP-seq
MIRT2344777	hsa-miR-3689c	CLIP-seq
MIRT2122481	hsa-miR-371-5p	CLIP-seq
MIRT2344778	hsa-miR-371b-3p	CLIP-seq
MIRT2122482	hsa-miR-371b-5p	CLIP-seq
MIRT2344779	hsa-miR-3913-5p	CLIP-seq
MIRT2344780	hsa-miR-3916	CLIP-seq
MIRT2344781	hsa-miR-3920	CLIP-seq
MIRT2344782	hsa-miR-3921	CLIP-seq
MIRT2122484	hsa-miR-3973	CLIP-seq
MIRT2122485	hsa-miR-412	CLIP-seq
MIRT2122486	hsa-miR-4260	CLIP-seq
MIRT2344783	hsa-miR-4262	CLIP-seq
MIRT2344784	hsa-miR-4275	CLIP-seq
MIRT1408225	hsa-miR-4282	CLIP-seq
MIRT2344785	hsa-miR-4288	CLIP-seq
MIRT2344786	hsa-miR-429	CLIP-seq
MIRT1408226	hsa-miR-4291	CLIP-seq
MIRT1408227	hsa-miR-4298	CLIP-seq
MIRT2122487	hsa-miR-4302	CLIP-seq
MIRT2122488	hsa-miR-4307	CLIP-seq
MIRT2344787	hsa-miR-4314	CLIP-seq
MIRT2344788	hsa-miR-4420	CLIP-seq
MIRT2344789	hsa-miR-4424	CLIP-seq
MIRT2344790	hsa-miR-4427	CLIP-seq
MIRT2344791	hsa-miR-4452	CLIP-seq
MIRT2344792	hsa-miR-4470	CLIP-seq
MIRT2122491	hsa-miR-4475	CLIP-seq
MIRT2122492	hsa-miR-448	CLIP-seq
MIRT2344793	hsa-miR-4490	CLIP-seq
MIRT2344794	hsa-miR-4495	CLIP-seq
MIRT1408235	hsa-miR-450b-3p	CLIP-seq
MIRT2122494	hsa-miR-4642	CLIP-seq
MIRT2344795	hsa-miR-4646-5p	CLIP-seq
MIRT2344796	hsa-miR-4650-5p	CLIP-seq
MIRT2344797	hsa-miR-4653-5p	CLIP-seq
MIRT2344798	hsa-miR-4659a-3p	CLIP-seq
MIRT2344799	hsa-miR-4659b-3p	CLIP-seq
MIRT2344800	hsa-miR-4680-3p	CLIP-seq
MIRT2344801	hsa-miR-4685-5p	CLIP-seq
MIRT2344802	hsa-miR-4715-3p	CLIP-seq
MIRT2122496	hsa-miR-4717-3p	CLIP-seq
MIRT2344803	hsa-miR-4738-3p	CLIP-seq
MIRT1408240	hsa-miR-4760-3p	CLIP-seq
MIRT1408241	hsa-miR-4761-5p	CLIP-seq
MIRT2122497	hsa-miR-4762-3p	CLIP-seq
MIRT2344804	hsa-miR-4766-3p	CLIP-seq
MIRT2344805	hsa-miR-4774-3p	CLIP-seq
MIRT2344806	hsa-miR-4781-3p	CLIP-seq
MIRT2122498	hsa-miR-4791	CLIP-seq
MIRT2344807	hsa-miR-4797-5p	CLIP-seq
MIRT1408243	hsa-miR-4802-3p	CLIP-seq
MIRT2344808	hsa-miR-499-3p	CLIP-seq
MIRT2344809	hsa-miR-499a-3p	CLIP-seq
MIRT2344810	hsa-miR-500a	CLIP-seq
MIRT2344811	hsa-miR-501-5p	CLIP-seq
MIRT2122499	hsa-miR-5096	CLIP-seq
MIRT2122500	hsa-miR-513a-5p	CLIP-seq
MIRT2344812	hsa-miR-516a-3p	CLIP-seq
MIRT2344813	hsa-miR-518a-3p	CLIP-seq
MIRT2344814	hsa-miR-518b	CLIP-seq
MIRT2344815	hsa-miR-518c	CLIP-seq
MIRT2344816	hsa-miR-518d-3p	CLIP-seq
MIRT2344817	hsa-miR-518f	CLIP-seq
MIRT2344818	hsa-miR-520d-5p	CLIP-seq
MIRT2122501	hsa-miR-520g	CLIP-seq
MIRT2122502	hsa-miR-520h	CLIP-seq
MIRT2344819	hsa-miR-524-5p	CLIP-seq
MIRT2344820	hsa-miR-548a-3p	CLIP-seq
MIRT2122503	hsa-miR-548a-5p	CLIP-seq
MIRT2122504	hsa-miR-548ab	CLIP-seq
MIRT2122505	hsa-miR-548ak	CLIP-seq
MIRT2122507	hsa-miR-548b-5p	CLIP-seq
MIRT2344821	hsa-miR-548c-3p	CLIP-seq
MIRT2122508	hsa-miR-548c-5p	CLIP-seq
MIRT2122509	hsa-miR-548d-5p	CLIP-seq
MIRT2344822	hsa-miR-548e	CLIP-seq
MIRT2344823	hsa-miR-548f	CLIP-seq
MIRT2122510	hsa-miR-548g	CLIP-seq
MIRT2122511	hsa-miR-548h	CLIP-seq
MIRT2122512	hsa-miR-548i	CLIP-seq
MIRT2122513	hsa-miR-548j	CLIP-seq
MIRT2122516	hsa-miR-548w	CLIP-seq
MIRT2122517	hsa-miR-548y	CLIP-seq
MIRT2122518	hsa-miR-559	CLIP-seq
MIRT2344824	hsa-miR-561	CLIP-seq
MIRT2344825	hsa-miR-562	CLIP-seq
MIRT2344826	hsa-miR-568	CLIP-seq
MIRT2122519	hsa-miR-569	CLIP-seq
MIRT2344827	hsa-miR-570	CLIP-seq
MIRT2122522	hsa-miR-607	CLIP-seq
MIRT2344828	hsa-miR-622	CLIP-seq
MIRT2344829	hsa-miR-632	CLIP-seq
MIRT2344830	hsa-miR-651	CLIP-seq
MIRT2344831	hsa-miR-665	CLIP-seq
MIRT2122523	hsa-miR-759	CLIP-seq
MIRT1408249	hsa-miR-761	CLIP-seq
MIRT2344832	hsa-miR-767-3p	CLIP-seq
MIRT1408250	hsa-miR-769-3p	CLIP-seq
MIRT2344833	hsa-miR-877	CLIP-seq
MIRT2344834	hsa-miR-889	CLIP-seq
MIRT2344835	hsa-miR-921	CLIP-seq
MIRT1408251	hsa-miR-922	CLIP-seq
MIRT2344836	hsa-miR-939	CLIP-seq
MIRT2122454	hsa-miR-142-5p	CLIP-seq
MIRT2122477	hsa-miR-340	CLIP-seq
MIRT2122521	hsa-miR-591	CLIP-seq
MIRT1408215	hsa-miR-214	CLIP-seq
MIRT1408222	hsa-miR-3619-5p	CLIP-seq
MIRT2122484	hsa-miR-3973	CLIP-seq
MIRT1408226	hsa-miR-4291	CLIP-seq
MIRT1408235	hsa-miR-450b-3p	CLIP-seq
MIRT2122501	hsa-miR-520g	CLIP-seq
MIRT2122502	hsa-miR-520h	CLIP-seq
MIRT2433767	hsa-miR-548k	CLIP-seq
MIRT1408249	hsa-miR-761	CLIP-seq
MIRT1408250	hsa-miR-769-3p	CLIP-seq
MIRT1408251	hsa-miR-922	CLIP-seq
MIRT2344731	hsa-miR-1183	CLIP-seq
MIRT2122454	hsa-miR-142-5p	CLIP-seq
MIRT2344748	hsa-miR-199a-5p	CLIP-seq
MIRT2344749	hsa-miR-199b-5p	CLIP-seq
MIRT2638017	hsa-miR-21	CLIP-seq
MIRT1408215	hsa-miR-214	CLIP-seq
MIRT2122461	hsa-miR-23a	CLIP-seq
MIRT2122462	hsa-miR-23b	CLIP-seq
MIRT2122463	hsa-miR-23c	CLIP-seq
MIRT2638018	hsa-miR-3143	CLIP-seq
MIRT2638019	hsa-miR-3171	CLIP-seq
MIRT2638020	hsa-miR-3185	CLIP-seq
MIRT2638021	hsa-miR-3186-5p	CLIP-seq
MIRT1408220	hsa-miR-338-5p	CLIP-seq
MIRT2122477	hsa-miR-340	CLIP-seq
MIRT2638022	hsa-miR-3618	CLIP-seq
MIRT1408222	hsa-miR-3619-5p	CLIP-seq
MIRT2122483	hsa-miR-3910	CLIP-seq
MIRT2344781	hsa-miR-3920	CLIP-seq
MIRT2122485	hsa-miR-412	CLIP-seq
MIRT2638023	hsa-miR-4274	CLIP-seq
MIRT1408226	hsa-miR-4291	CLIP-seq
MIRT2122491	hsa-miR-4475	CLIP-seq
MIRT1408231	hsa-miR-4477a	CLIP-seq
MIRT2638024	hsa-miR-4635	CLIP-seq
MIRT2638025	hsa-miR-4709-3p	CLIP-seq
MIRT2638026	hsa-miR-4755-3p	CLIP-seq
MIRT1408240	hsa-miR-4760-3p	CLIP-seq
MIRT1408241	hsa-miR-4761-5p	CLIP-seq
MIRT2122497	hsa-miR-4762-3p	CLIP-seq
MIRT2638027	hsa-miR-4778-5p	CLIP-seq
MIRT2638028	hsa-miR-4786-5p	CLIP-seq
MIRT1408243	hsa-miR-4802-3p	CLIP-seq
MIRT2344811	hsa-miR-501-5p	CLIP-seq
MIRT2344818	hsa-miR-520d-5p	CLIP-seq
MIRT2344819	hsa-miR-524-5p	CLIP-seq
MIRT2638029	hsa-miR-543	CLIP-seq
MIRT2122503	hsa-miR-548a-5p	CLIP-seq
MIRT2122504	hsa-miR-548ab	CLIP-seq
MIRT2638030	hsa-miR-548ac	CLIP-seq
MIRT2122505	hsa-miR-548ak	CLIP-seq
MIRT2122506	hsa-miR-548an	CLIP-seq
MIRT2122507	hsa-miR-548b-5p	CLIP-seq
MIRT2122508	hsa-miR-548c-5p	CLIP-seq
MIRT2638031	hsa-miR-548d-3p	CLIP-seq
MIRT2122509	hsa-miR-548d-5p	CLIP-seq
MIRT2122511	hsa-miR-548h	CLIP-seq
MIRT2122512	hsa-miR-548i	CLIP-seq
MIRT2122513	hsa-miR-548j	CLIP-seq
MIRT2122514	hsa-miR-548n	CLIP-seq
MIRT2122515	hsa-miR-548t	CLIP-seq
MIRT2122516	hsa-miR-548w	CLIP-seq
MIRT2122517	hsa-miR-548y	CLIP-seq
MIRT2638032	hsa-miR-548z	CLIP-seq
MIRT2122518	hsa-miR-559	CLIP-seq
MIRT2344826	hsa-miR-568	CLIP-seq
MIRT2638033	hsa-miR-590-5p	CLIP-seq
MIRT1408249	hsa-miR-761	CLIP-seq
MIRT2638034	hsa-miR-802	CLIP-seq
MIRT1408251	hsa-miR-922	CLIP-seq
MIRT2692592	hsa-miR-323b-3p	CLIP-seq
MIRT2638022	hsa-miR-3618	CLIP-seq
MIRT2638023	hsa-miR-4274	CLIP-seq
MIRT1408241	hsa-miR-4761-5p	CLIP-seq
MIRT1408243	hsa-miR-4802-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17158449, 17449468, 21512573, 21903422, 22081109, 22158122, 25416956, 32296183, 32707033, 35271311, 36179048
GO:0005783	Component	Endoplasmic reticulum	IDA	15327770
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	TAS
GO:0007249	Process	Canonical NF-kappaB signal transduction	IDA	1406630, 19675569, 34721373
GO:0008270	Function	Zinc ion binding	IDA	22158122
GO:0008270	Function	Zinc ion binding	IEA
GO:0009617	Process	Response to bacterium	IEA
GO:0010008	Component	Endosome membrane	TAS
GO:0010507	Process	Negative regulation of autophagy	IEA
GO:0010507	Process	Negative regulation of autophagy	TAS	21976705
GO:0038061	Process	Non-canonical NF-kappaB signal transduction	IDA	15327770
GO:0038061	Process	Non-canonical NF-kappaB signal transduction	IEA
GO:0038066	Process	P38MAPK cascade	IDA	10330143, 11460167
GO:0042742	Process	Defense response to bacterium	IDA	11460167
GO:0042742	Process	Defense response to bacterium	IDA	18079694
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IBA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	9346484, 11460167
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	15327770, 18079694, 22158122
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IMP	23487264
GO:0043124	Process	Negative regulation of canonical NF-kappaB signal transduction	IDA	25038658
GO:0043130	Function	Ubiquitin binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0060090	Function	Molecular adaptor activity	IDA	15327770
GO:0070062	Component	Extracellular exosome	HDA	18570454
GO:0070530	Function	K63-linked polyubiquitin modification-dependent protein binding	IDA	15327770, 22158122
GO:0070530	Function	K63-linked polyubiquitin modification-dependent protein binding	IEA

Other IDs

• MIM: 300480
• HGNC: 30681
• e!Ensembl: ENSG00000157625

Protein

• UniProt ID: Q8N5C8
• Protein name: TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
• Protein function: Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF) (PubMed:14633987, PubMed:14766965, PubMed:15327770, PubMed:22158
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02845	CUE	9 → 50	CUE domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Constitutively overexpressed in certain tumor tissues. {ECO:0000269|PubMed:14670075}.; TISSUE SPECIFICITY: [Isoform 1]: Major transcript. {ECO:0000269|PubMed:14766965}.; TISSUE SPECIFICITY: [Isoform 2]: Minor transcri
• Sequence:

  MAQSSPQLDIQVLHDLRQRFPEIPEGVVSQCMLQNNNNLEACCRALSQESSKYLYMEYHS
  PDDNRMNRNRLLHINLGIHSPSSYHPGDGAQLNGGRTLVHSSSDGHIDPQHAAGKQLICL
  VQEPHSAPAVVAATPNYNPFFMNEQNRSAATPPSQPPQQPSSMQTGMNPSAMQGPSPPPP
  PPSYMHIPRYSTNPITVTVSQNLPSGQTVPRALQILPQIPSNLYGSPGSIYIRQTSQSSS
  GRQTPQSTPWQSSPQGPVPHYSQRPLPVYPHQQNYQPSQYSPKQQQIPQSAYHSPPPSQC
  PSPFSSPQHQVQPSQLGHIFMPPSPSTTPPHPYQQGPPSYQKQGSHSVAYLPYTASSLSK
  GSMKKIEITVEPSQRPGTAINRSPSPISNQPSPRNQHSLYTATTPPSSSPSRGISSQPKP
  PFSVNPVYITYTQPTGPSCTPSPSPRVIPNPTTVFKITVGRATTENLLNLVDQEERSAAP
  EPIQPISVIPGSGGEKGSHKYQRSSSSGSDDYAYTQALLLHQRARMERLAKQLKLEKEEL
  ERLKSEVNGMEHDLMQRRLRRVSCTTAIPTPEEMTRLRSMNRQLQINVDCTLKEVDLLQS
  RGNFDPKAMNNFYDNIEPGPVVPPKPSKKDSSDPCTIERKARRISVTSKVQADIHDTQAA
  AADEHRTGSTQSPRTQPRDEDYEGAPWNCDSCTFLNHPALNRCEQCEMPRYT

• Sequence length: 712

Pathways

KEGG:

NF-kappa B signaling pathway
NOD-like receptor signaling pathway
IL-17 signaling pathway
TNF signaling pathway
Alcoholic liver disease
Pathogenic Escherichia coli infection
Shigellosis
Salmonella infection

Reactome:

NOD1/2 Signaling Pathway
FCERI mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
TNFR1-induced NFkappaB signaling pathway
CLEC7A (Dectin-1) signaling
TICAM1,TRAF6-dependent induction of TAK1 complex
Interleukin-1 signaling
IRAK2 mediated activation of TAK1 complex
TRAF6-mediated induction of TAK1 complex within TLR4 complex
Alpha-protein kinase 1 signaling pathway
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation