LCLAT1 (lysocardiolipin acyltransferase 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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253558 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Lysocardiolipin acyltransferase 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LCLAT1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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1AGPAT8, AGPAT8, ALCAT1, HSRG1849, LPLAT6, LYCAT, UNQ1849 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p23.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q6UWP7 | |||||||||||||||
Protein name | Lysocardiolipin acyltransferase 1 (EC 2.3.1.-) (1-acylglycerol-3-phosphate O-acyltransferase 8) (1-AGP acyltransferase 8) (1-AGPAT 8) (EC 2.3.1.51) (Acyl-CoA:lysocardiolipin acyltransferase 1) | |||||||||||||||
Protein function | Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling (By similarity). Recognizes both monolysocardiolipin and dilysocardiolipin as subs | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed at higher level in heart, kidney and pancreas than in brain, spleen, liver, lung, small intestine and placenta. {ECO:0000269|PubMed:16620771, ECO:0000269|PubMed:19075029}. | |||||||||||||||
Sequence |
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Sequence length | 414 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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