Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	2535
Gene name	Frizzled class receptor 2
Gene symbol	FZD2
Synonyms (NCBI Gene)	Fz2OMOD2fz-2fzE2hFz2
Chromosome	17
Chromosome location	17q21.31
Summary	This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that i

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1223920489	G>A	Likely-pathogenic	Coding sequence variant, missense variant
rs1555657045	G>A	Likely-pathogenic	Stop gained, coding sequence variant
rs1555657073	G>T	Likely-pathogenic	Coding sequence variant, missense variant
rs1555657074	GC>TT	Likely-pathogenic	Coding sequence variant, missense variant
rs1568105562	T>G	Likely-pathogenic	Missense variant, coding sequence variant
rs1568105666	G>A	Pathogenic	Coding sequence variant, stop gained

522

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miRTarBase ID	miRNA	Experiments	Reference
MIRT718685	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT718684	hsa-miR-6721-5p	HITS-CLIP	19536157
MIRT718683	hsa-miR-2117	HITS-CLIP	19536157
MIRT718682	hsa-miR-4425	HITS-CLIP	19536157
MIRT718681	hsa-miR-3147	HITS-CLIP	19536157
MIRT718680	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT718679	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT611376	hsa-miR-8485	HITS-CLIP	19536157
MIRT611375	hsa-miR-329-3p	HITS-CLIP	19536157
MIRT611374	hsa-miR-362-3p	HITS-CLIP	19536157
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	19536157
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	19536157
MIRT694764	hsa-miR-6732-3p	HITS-CLIP	23313552
MIRT694763	hsa-miR-5583-3p	HITS-CLIP	23313552
MIRT694762	hsa-miR-10a-5p	HITS-CLIP	23313552
MIRT694761	hsa-miR-10b-5p	HITS-CLIP	23313552
MIRT694760	hsa-miR-3618	HITS-CLIP	23313552
MIRT694759	hsa-miR-934	HITS-CLIP	23313552
MIRT694758	hsa-miR-4711-3p	HITS-CLIP	23313552
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT668244	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT668243	hsa-miR-8073	HITS-CLIP	23824327
MIRT668242	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT668241	hsa-miR-566	HITS-CLIP	23824327
MIRT668240	hsa-miR-4279	HITS-CLIP	23824327
MIRT668239	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620331	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620330	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT620329	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620331	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620330	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT620329	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620331	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620330	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT620329	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT718685	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT718684	hsa-miR-6721-5p	HITS-CLIP	19536157
MIRT718683	hsa-miR-2117	HITS-CLIP	19536157
MIRT718682	hsa-miR-4425	HITS-CLIP	19536157
MIRT718681	hsa-miR-3147	HITS-CLIP	19536157
MIRT718680	hsa-miR-4753-3p	HITS-CLIP	19536157
MIRT718679	hsa-miR-6809-3p	HITS-CLIP	19536157
MIRT611376	hsa-miR-8485	HITS-CLIP	19536157
MIRT611375	hsa-miR-329-3p	HITS-CLIP	19536157
MIRT611374	hsa-miR-362-3p	HITS-CLIP	19536157
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	19536157
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	19536157
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	19536157
MIRT694764	hsa-miR-6732-3p	HITS-CLIP	23313552
MIRT694763	hsa-miR-5583-3p	HITS-CLIP	23313552
MIRT694762	hsa-miR-10a-5p	HITS-CLIP	23313552
MIRT694761	hsa-miR-10b-5p	HITS-CLIP	23313552
MIRT694760	hsa-miR-3618	HITS-CLIP	23313552
MIRT694759	hsa-miR-934	HITS-CLIP	23313552
MIRT694758	hsa-miR-4711-3p	HITS-CLIP	23313552
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT668244	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT668243	hsa-miR-8073	HITS-CLIP	23824327
MIRT668242	hsa-miR-6789-3p	HITS-CLIP	23824327
MIRT668241	hsa-miR-566	HITS-CLIP	23824327
MIRT668240	hsa-miR-4279	HITS-CLIP	23824327
MIRT668239	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620331	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620330	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT620329	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620331	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620330	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT620329	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT620331	hsa-miR-6838-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT620330	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT620329	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT611376	hsa-miR-8485	HITS-CLIP	23824327
MIRT611375	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT611374	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT611373	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611372	hsa-miR-6793-3p	HITS-CLIP	23824327
MIRT611371	hsa-miR-6758-3p	HITS-CLIP	23824327
MIRT1007787	hsa-miR-1205	CLIP-seq
MIRT1007788	hsa-miR-1252	CLIP-seq
MIRT1007789	hsa-miR-1264	CLIP-seq
MIRT1007790	hsa-miR-1273	CLIP-seq
MIRT1007791	hsa-miR-151-3p	CLIP-seq
MIRT1007792	hsa-miR-1827	CLIP-seq
MIRT1007793	hsa-miR-1909	CLIP-seq
MIRT1007794	hsa-miR-2114	CLIP-seq
MIRT1007795	hsa-miR-3119	CLIP-seq
MIRT1007796	hsa-miR-3153	CLIP-seq
MIRT1007797	hsa-miR-3613-3p	CLIP-seq
MIRT1007798	hsa-miR-3689a-3p	CLIP-seq
MIRT1007799	hsa-miR-3689c	CLIP-seq
MIRT1007800	hsa-miR-3689d	CLIP-seq
MIRT1007801	hsa-miR-371-5p	CLIP-seq
MIRT1007802	hsa-miR-371b-5p	CLIP-seq
MIRT1007803	hsa-miR-3929	CLIP-seq
MIRT1007804	hsa-miR-4261	CLIP-seq
MIRT1007805	hsa-miR-4271	CLIP-seq
MIRT1007806	hsa-miR-4418	CLIP-seq
MIRT1007807	hsa-miR-4419b	CLIP-seq
MIRT1007808	hsa-miR-4432	CLIP-seq
MIRT1007809	hsa-miR-4433	CLIP-seq
MIRT1007810	hsa-miR-4459	CLIP-seq
MIRT1007811	hsa-miR-4463	CLIP-seq
MIRT1007812	hsa-miR-4478	CLIP-seq
MIRT1007813	hsa-miR-4486	CLIP-seq
MIRT1007814	hsa-miR-4496	CLIP-seq
MIRT1007815	hsa-miR-4499	CLIP-seq
MIRT1007816	hsa-miR-4514	CLIP-seq
MIRT1007817	hsa-miR-451b	CLIP-seq
MIRT1007818	hsa-miR-4533	CLIP-seq
MIRT1007819	hsa-miR-4649-3p	CLIP-seq
MIRT1007820	hsa-miR-4649-5p	CLIP-seq
MIRT1007821	hsa-miR-4692	CLIP-seq
MIRT1007822	hsa-miR-4696	CLIP-seq
MIRT1007823	hsa-miR-4716-3p	CLIP-seq
MIRT1007824	hsa-miR-4719	CLIP-seq
MIRT1007825	hsa-miR-4722-5p	CLIP-seq
MIRT1007826	hsa-miR-4725-3p	CLIP-seq
MIRT1007827	hsa-miR-4728-5p	CLIP-seq
MIRT1007828	hsa-miR-4734	CLIP-seq
MIRT1007829	hsa-miR-4747-5p	CLIP-seq
MIRT1007830	hsa-miR-4756-3p	CLIP-seq
MIRT1007831	hsa-miR-4768-3p	CLIP-seq
MIRT1007832	hsa-miR-4793-3p	CLIP-seq
MIRT1007833	hsa-miR-485-5p	CLIP-seq
MIRT1007834	hsa-miR-490-3p	CLIP-seq
MIRT1007835	hsa-miR-508-5p	CLIP-seq
MIRT1007836	hsa-miR-509-3-5p	CLIP-seq
MIRT1007837	hsa-miR-509-5p	CLIP-seq
MIRT1007838	hsa-miR-604	CLIP-seq
MIRT1007839	hsa-miR-625	CLIP-seq
MIRT1007840	hsa-miR-647	CLIP-seq
MIRT1007841	hsa-miR-649	CLIP-seq
MIRT1007842	hsa-miR-656	CLIP-seq
MIRT1007843	hsa-miR-661	CLIP-seq
MIRT1007844	hsa-miR-766	CLIP-seq
MIRT1007845	hsa-miR-890	CLIP-seq
MIRT1007846	hsa-miR-940	CLIP-seq
MIRT1007790	hsa-miR-1273	CLIP-seq
MIRT1007792	hsa-miR-1827	CLIP-seq
MIRT1007797	hsa-miR-3613-3p	CLIP-seq
MIRT1007801	hsa-miR-371-5p	CLIP-seq
MIRT1007802	hsa-miR-371b-5p	CLIP-seq
MIRT1998613	hsa-miR-3926	CLIP-seq
MIRT1998614	hsa-miR-4266	CLIP-seq
MIRT1998615	hsa-miR-4422	CLIP-seq
MIRT1007808	hsa-miR-4432	CLIP-seq
MIRT1007809	hsa-miR-4433	CLIP-seq
MIRT1007810	hsa-miR-4459	CLIP-seq
MIRT1007813	hsa-miR-4486	CLIP-seq
MIRT1998616	hsa-miR-4509	CLIP-seq
MIRT1007817	hsa-miR-451b	CLIP-seq
MIRT1007820	hsa-miR-4649-5p	CLIP-seq
MIRT1998617	hsa-miR-4659a-3p	CLIP-seq
MIRT1998618	hsa-miR-4659b-3p	CLIP-seq
MIRT1998619	hsa-miR-4695-5p	CLIP-seq
MIRT1007822	hsa-miR-4696	CLIP-seq
MIRT1998620	hsa-miR-4744	CLIP-seq
MIRT1007831	hsa-miR-4768-3p	CLIP-seq
MIRT1998621	hsa-miR-4778-3p	CLIP-seq
MIRT1998622	hsa-miR-4779	CLIP-seq
MIRT1998623	hsa-miR-4786-5p	CLIP-seq
MIRT1007832	hsa-miR-4793-3p	CLIP-seq
MIRT1998624	hsa-miR-4799-5p	CLIP-seq
MIRT1998625	hsa-miR-483-3p	CLIP-seq
MIRT1998626	hsa-miR-486-5p	CLIP-seq
MIRT1007835	hsa-miR-508-5p	CLIP-seq
MIRT1998627	hsa-miR-548s	CLIP-seq
MIRT1998628	hsa-miR-651	CLIP-seq
MIRT1007843	hsa-miR-661	CLIP-seq
MIRT1007844	hsa-miR-766	CLIP-seq
MIRT1007846	hsa-miR-940	CLIP-seq
MIRT1007790	hsa-miR-1273	CLIP-seq
MIRT2232335	hsa-miR-2115	CLIP-seq
MIRT2232336	hsa-miR-3614-5p	CLIP-seq
MIRT1007800	hsa-miR-3689d	CLIP-seq
MIRT1007801	hsa-miR-371-5p	CLIP-seq
MIRT1007802	hsa-miR-371b-5p	CLIP-seq
MIRT1998613	hsa-miR-3926	CLIP-seq
MIRT2232337	hsa-miR-4252	CLIP-seq
MIRT1998614	hsa-miR-4266	CLIP-seq
MIRT2232338	hsa-miR-4305	CLIP-seq
MIRT2232339	hsa-miR-4318	CLIP-seq
MIRT1007809	hsa-miR-4433	CLIP-seq
MIRT1007810	hsa-miR-4459	CLIP-seq
MIRT2232340	hsa-miR-4484	CLIP-seq
MIRT1007813	hsa-miR-4486	CLIP-seq
MIRT1007817	hsa-miR-451b	CLIP-seq
MIRT2232341	hsa-miR-4640-5p	CLIP-seq
MIRT1007820	hsa-miR-4649-5p	CLIP-seq
MIRT1998619	hsa-miR-4695-5p	CLIP-seq
MIRT2232342	hsa-miR-4726-5p	CLIP-seq
MIRT1007831	hsa-miR-4768-3p	CLIP-seq
MIRT1998622	hsa-miR-4779	CLIP-seq
MIRT1998623	hsa-miR-4786-5p	CLIP-seq
MIRT1007832	hsa-miR-4793-3p	CLIP-seq
MIRT1998625	hsa-miR-483-3p	CLIP-seq
MIRT1998626	hsa-miR-486-5p	CLIP-seq
MIRT1007835	hsa-miR-508-5p	CLIP-seq
MIRT2232343	hsa-miR-516a-3p	CLIP-seq
MIRT1998627	hsa-miR-548s	CLIP-seq
MIRT1998628	hsa-miR-651	CLIP-seq
MIRT1007843	hsa-miR-661	CLIP-seq
MIRT2232344	hsa-miR-671-5p	CLIP-seq
MIRT1007844	hsa-miR-766	CLIP-seq
MIRT2232336	hsa-miR-3614-5p	CLIP-seq
MIRT2232337	hsa-miR-4252	CLIP-seq
MIRT2232341	hsa-miR-4640-5p	CLIP-seq
MIRT2232342	hsa-miR-4726-5p	CLIP-seq
MIRT1007831	hsa-miR-4768-3p	CLIP-seq
MIRT2232344	hsa-miR-671-5p	CLIP-seq
MIRT1007792	hsa-miR-1827	CLIP-seq
MIRT1998614	hsa-miR-4266	CLIP-seq
MIRT1998619	hsa-miR-4695-5p	CLIP-seq
MIRT1998622	hsa-miR-4779	CLIP-seq
MIRT1998625	hsa-miR-483-3p	CLIP-seq
MIRT1998626	hsa-miR-486-5p	CLIP-seq
MIRT1998628	hsa-miR-651	CLIP-seq
MIRT1007846	hsa-miR-940	CLIP-seq
MIRT1007792	hsa-miR-1827	CLIP-seq
MIRT1998614	hsa-miR-4266	CLIP-seq
MIRT1998619	hsa-miR-4695-5p	CLIP-seq
MIRT1998622	hsa-miR-4779	CLIP-seq
MIRT1998625	hsa-miR-483-3p	CLIP-seq
MIRT1998626	hsa-miR-486-5p	CLIP-seq
MIRT1998628	hsa-miR-651	CLIP-seq
MIRT2536054	hsa-miR-10a	CLIP-seq
MIRT2536055	hsa-miR-10b	CLIP-seq
MIRT1007789	hsa-miR-1264	CLIP-seq
MIRT1007790	hsa-miR-1273	CLIP-seq
MIRT1007792	hsa-miR-1827	CLIP-seq
MIRT2536056	hsa-miR-3145-5p	CLIP-seq
MIRT2536057	hsa-miR-3151	CLIP-seq
MIRT2536058	hsa-miR-3180	CLIP-seq
MIRT2536059	hsa-miR-3180-3p	CLIP-seq
MIRT2536060	hsa-miR-3196	CLIP-seq
MIRT1007797	hsa-miR-3613-3p	CLIP-seq
MIRT1007801	hsa-miR-371-5p	CLIP-seq
MIRT1007802	hsa-miR-371b-5p	CLIP-seq
MIRT1998614	hsa-miR-4266	CLIP-seq
MIRT1007808	hsa-miR-4432	CLIP-seq
MIRT1007813	hsa-miR-4486	CLIP-seq
MIRT1007816	hsa-miR-4514	CLIP-seq
MIRT1007817	hsa-miR-451b	CLIP-seq
MIRT1007820	hsa-miR-4649-5p	CLIP-seq
MIRT1007821	hsa-miR-4692	CLIP-seq
MIRT1998619	hsa-miR-4695-5p	CLIP-seq
MIRT1007822	hsa-miR-4696	CLIP-seq
MIRT1998622	hsa-miR-4779	CLIP-seq
MIRT1007832	hsa-miR-4793-3p	CLIP-seq
MIRT2536061	hsa-miR-4796-3p	CLIP-seq
MIRT1998625	hsa-miR-483-3p	CLIP-seq
MIRT1998626	hsa-miR-486-5p	CLIP-seq
MIRT1007835	hsa-miR-508-5p	CLIP-seq
MIRT2536062	hsa-miR-548ae	CLIP-seq
MIRT2536063	hsa-miR-548aj	CLIP-seq
MIRT2536064	hsa-miR-548am	CLIP-seq
MIRT2536065	hsa-miR-548c-3p	CLIP-seq
MIRT2536066	hsa-miR-548t	CLIP-seq
MIRT2536067	hsa-miR-548x	CLIP-seq
MIRT1998628	hsa-miR-651	CLIP-seq
MIRT1007843	hsa-miR-661	CLIP-seq
MIRT1007844	hsa-miR-766	CLIP-seq
MIRT1007846	hsa-miR-940	CLIP-seq
MIRT1007790	hsa-miR-1273	CLIP-seq
MIRT1007792	hsa-miR-1827	CLIP-seq
MIRT2536056	hsa-miR-3145-5p	CLIP-seq
MIRT2536057	hsa-miR-3151	CLIP-seq
MIRT2536058	hsa-miR-3180	CLIP-seq
MIRT2536059	hsa-miR-3180-3p	CLIP-seq
MIRT2536060	hsa-miR-3196	CLIP-seq
MIRT1007797	hsa-miR-3613-3p	CLIP-seq
MIRT1007801	hsa-miR-371-5p	CLIP-seq
MIRT1007802	hsa-miR-371b-5p	CLIP-seq
MIRT1998614	hsa-miR-4266	CLIP-seq
MIRT1007808	hsa-miR-4432	CLIP-seq
MIRT1007813	hsa-miR-4486	CLIP-seq
MIRT1007817	hsa-miR-451b	CLIP-seq
MIRT1007820	hsa-miR-4649-5p	CLIP-seq
MIRT1998619	hsa-miR-4695-5p	CLIP-seq
MIRT1007822	hsa-miR-4696	CLIP-seq
MIRT1998622	hsa-miR-4779	CLIP-seq
MIRT1007832	hsa-miR-4793-3p	CLIP-seq
MIRT2536061	hsa-miR-4796-3p	CLIP-seq
MIRT1998625	hsa-miR-483-3p	CLIP-seq
MIRT1998626	hsa-miR-486-5p	CLIP-seq
MIRT1007835	hsa-miR-508-5p	CLIP-seq
MIRT2536062	hsa-miR-548ae	CLIP-seq
MIRT2536063	hsa-miR-548aj	CLIP-seq
MIRT2536064	hsa-miR-548am	CLIP-seq
MIRT2536066	hsa-miR-548t	CLIP-seq
MIRT2536067	hsa-miR-548x	CLIP-seq
MIRT1998628	hsa-miR-651	CLIP-seq
MIRT1007843	hsa-miR-661	CLIP-seq
MIRT1007844	hsa-miR-766	CLIP-seq
MIRT1007846	hsa-miR-940	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003149	Process	Membranous septum morphogenesis	IEA
GO:0003150	Process	Muscular septum morphogenesis	IEA
GO:0003151	Process	Outflow tract morphogenesis	IEA
GO:0004888	Function	Transmembrane signaling receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0005515	Function	Protein binding	IPI	25417160, 27680706, 29748286
GO:0005737	Component	Cytoplasm	IDA	19038973
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	18929644
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0007165	Process	Signal transduction	IEA
GO:0007166	Process	Cell surface receptor signaling pathway	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007267	Process	Cell-cell signaling	IEA
GO:0007608	Process	Sensory perception of smell	IEA
GO:0016020	Component	Membrane	IEA
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0016055	Process	Wnt signaling pathway	IMP	29276006
GO:0017147	Function	Wnt-protein binding	IBA
GO:0017147	Function	Wnt-protein binding	NAS	24431302
GO:0030165	Function	PDZ domain binding	IEA
GO:0030165	Function	PDZ domain binding	IPI	19388021
GO:0030182	Process	Neuron differentiation	ISS
GO:0030669	Component	Clathrin-coated endocytic vesicle membrane	TAS
GO:0035567	Process	Non-canonical Wnt signaling pathway	IBA
GO:0042813	Function	Wnt receptor activity	IBA
GO:0042813	Function	Wnt receptor activity	IDA	28733458
GO:0042813	Function	Wnt receptor activity	IEA
GO:0042813	Function	Wnt receptor activity	NAS	24431302
GO:0045446	Process	Endothelial cell differentiation	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	18215320, 18929644
GO:0060022	Process	Hard palate development	IEA
GO:0060070	Process	Canonical Wnt signaling pathway	IBA
GO:0060070	Process	Canonical Wnt signaling pathway	IDA	18215320, 18929644, 20802536, 28733458
GO:0060070	Process	Canonical Wnt signaling pathway	IEA
GO:0060071	Process	Wnt signaling pathway, planar cell polarity pathway	NAS	24431302
GO:0060119	Process	Inner ear receptor cell development	IEA
GO:0060412	Process	Ventricular septum morphogenesis	IEA
GO:0090103	Process	Cochlea morphogenesis	IEA

MIM	HGNC	e!Ensembl
600667	4040	ENSG00000180340

Q14332

Protein name

Frizzled-2 (Fz-2) (hFz2) (FzE2)

Protein function

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activat

PDB

6C0B , 7N95 , 7N97 , 7N9S , 7X8P

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01392	Fz	39 → 146	Fz domain	Domain
PF01534	Frizzled	235 → 555	Frizzled/Smoothened family membrane region	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. In the adult, mainly found in heart, placenta, skeletal muscle, lung, kidney, pancreas, prostate, testis, ovary and colon. In the fetus, expressed in brain, lung and kidney. Low levels in fetal liver.

Sequence

MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNL
LGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQG
CEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTP
GGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEE
TRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVL
QERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKW
GHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPL
FVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACY
FYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIW
SGKTLHSWRKFYTRLTNSRHGETTV

Sequence length

565

Interactions

View interactions

	KEGG		Reactome
	mTOR signaling pathway Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells Melanogenesis Cushing syndrome Alzheimer disease Pathways of neurodegeneration - multiple diseases Human papillomavirus infection Pathways in cancer Proteoglycans in cancer Basal cell carcinoma Breast cancer Hepatocellular carcinoma Gastric cancer		Ca2+ pathway Asymmetric localization of PCP proteins Disassembly of the destruction complex and recruitment of AXIN to the membrane WNT5A-dependent internalization of FZD2, FZD5 and ROR2

Show/Hide Causal Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Autosomal dominant omodysplasia	Likely pathogenic; Pathogenic	rs1555657073, rs1568105666	RCV004698842 RCV000754771
Autosomal dominant Robinow syndrome 1	Likely pathogenic; Pathogenic	rs1223920489, rs1568105666, rs2144572390	RCV001353073 RCV001353074 RCV001353075
Autosomal dominant Robinow syndrome 2	Likely pathogenic; Pathogenic	rs1223920489, rs1555657074, rs1568105666	RCV000577904 RCV000577879 RCV000989930
Autosomal dominant Robinow syndrome 3	Likely pathogenic; Pathogenic	rs1555657073	RCV000577887
Short stature	Likely pathogenic	rs1568105562	RCV000736149

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
FZD2-related disorder	Benign; Likely benign; Uncertain significance; Conflicting classifications of pathogenicity	rs141791958, rs577012342, rs373390114, rs764411531, rs1430553474, rs2544584399, rs2544583916, rs1057399025, rs1970847214, rs2544583910, rs1970849186, rs138090948, rs150027138, rs143455997	RCV003951072 RCV003933456 RCV003933356 RCV003953924 RCV003412483 RCV003400072 RCV003979391 RCV003973964 RCV003933969 RCV003979106 RCV003976495 RCV003903306 RCV003926209 RCV003920646
Keratoconus	Benign; Likely benign	rs758351214	RCV000678664
See cases	Uncertain significance	rs2144572308	RCV002253148

Show/Hide Text Mining Associations (39)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma	Associate	30841855
Adenoma Pleomorphic	Associate	34986855
Amyotrophic Lateral Sclerosis	Associate	30924074
Anodontia	Associate	32141827
Arthritis Psoriatic	Associate	20376066
Arthritis Rheumatoid	Associate	10688908
Breast Neoplasms	Associate	31907106
Carcinoma Hepatocellular	Associate	32755597
Carcinoma Renal Cell	Associate	33804101
Carcinoma Squamous Cell	Associate	33485313
Chemical and Drug Induced Liver Injury	Inhibit	32141827
Colorectal Neoplasms	Associate	24504536
Drug Related Side Effects and Adverse Reactions	Associate	33255261
Esophageal Neoplasms	Stimulate	24022664
Glioblastoma	Inhibit	33857857
Glioblastoma	Associate	38167429
Glioma	Associate	21205070, 34657400
Hernias Diaphragmatic Congenital	Associate	21525063
Hypoxia	Associate	32141827
Idiopathic Pulmonary Fibrosis	Stimulate	18478089
Leiomyoma	Associate	12909487
Lymphoma	Associate	18024791
Lymphoma Mantle Cell	Associate	18024791
Melanoma	Associate	19946729
Neoplasm Metastasis	Associate	31595151, 31907106
Neoplasms	Associate	16756720, 19696931, 23442549, 26132195, 30183492, 31595151, 34296206, 34986855
Neoplasms	Inhibit	33857857
Omodysplasia 2	Associate	25759469
Pancreatic Neoplasms	Stimulate	33618667
Pentalogy of Cantrell	Associate	21525063
Precursor B Cell Lymphoblastic Leukemia Lymphoma	Associate	10500199
Prostatic Neoplasms	Associate	28030815, 35930737
Retinal Neoplasms	Associate	19946729
Ring Chromosome 20 Syndrome	Associate	32141827
Robinow Syndrome	Associate	29276006
Scleroderma Diffuse	Stimulate	22328118
Squamous Cell Carcinoma of Head and Neck	Associate	31595151, 35886008
Tongue Neoplasms	Associate	31595151
Wilms Tumor	Associate	19696931

FZD2 (frizzled class receptor 2)