Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	245806
Gene name	Vestigial like family member 2
Gene symbol	VGLL2
Synonyms (NCBI Gene)	VGL2VITO1
Chromosome	6
Chromosome location	6q22.1
Summary	This gene encodes a protein with a transcriptional enhancer factor 1 (TEF-1) interaction domain. The encoded protein may act as a co-factor of TEF-1 regulated gene expression during skeletal muscle development. Alternatively spliced transcript variants en

119

Show/Hide all (119)

miRTarBase ID	miRNA	Experiments	Reference
MIRT552960	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT552958	hsa-miR-1295b-5p	HITS-CLIP	23313552
MIRT552957	hsa-miR-1912	HITS-CLIP	23313552
MIRT552956	hsa-miR-3130-5p	HITS-CLIP	23313552
MIRT552955	hsa-miR-4482-5p	HITS-CLIP	23313552
MIRT552954	hsa-miR-369-3p	HITS-CLIP	23313552
MIRT552953	hsa-miR-5692b	HITS-CLIP	23313552
MIRT552952	hsa-miR-5692c	HITS-CLIP	23313552
MIRT552951	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT552950	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT552949	hsa-miR-586	HITS-CLIP	23313552
MIRT693776	hsa-miR-148a-3p	HITS-CLIP	23313552
MIRT693775	hsa-miR-148b-3p	HITS-CLIP	23313552
MIRT693774	hsa-miR-152-3p	HITS-CLIP	23313552
MIRT693773	hsa-miR-1825	HITS-CLIP	23313552
MIRT552948	hsa-miR-5689	HITS-CLIP	23313552
MIRT552945	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT552944	hsa-miR-5583-5p	HITS-CLIP	23313552
MIRT552960	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT552959	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT552958	hsa-miR-1295b-5p	PAR-CLIP	21572407
MIRT552957	hsa-miR-1912	PAR-CLIP	21572407
MIRT552956	hsa-miR-3130-5p	PAR-CLIP	21572407
MIRT552955	hsa-miR-4482-5p	PAR-CLIP	21572407
MIRT552954	hsa-miR-369-3p	PAR-CLIP	21572407
MIRT552953	hsa-miR-5692b	PAR-CLIP	21572407
MIRT552952	hsa-miR-5692c	PAR-CLIP	21572407
MIRT552951	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT552950	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT552949	hsa-miR-586	PAR-CLIP	21572407
MIRT552948	hsa-miR-5689	PAR-CLIP	21572407
MIRT552947	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT552946	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT552945	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT552944	hsa-miR-5583-5p	PAR-CLIP	21572407
MIRT552960	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT552958	hsa-miR-1295b-5p	HITS-CLIP	23313552
MIRT552957	hsa-miR-1912	HITS-CLIP	23313552
MIRT552956	hsa-miR-3130-5p	HITS-CLIP	23313552
MIRT552955	hsa-miR-4482-5p	HITS-CLIP	23313552
MIRT552954	hsa-miR-369-3p	HITS-CLIP	23313552
MIRT552953	hsa-miR-5692b	HITS-CLIP	23313552
MIRT552952	hsa-miR-5692c	HITS-CLIP	23313552
MIRT552951	hsa-miR-410-3p	HITS-CLIP	23313552
MIRT552950	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT552949	hsa-miR-586	HITS-CLIP	23313552
MIRT693776	hsa-miR-148a-3p	HITS-CLIP	23313552
MIRT693775	hsa-miR-148b-3p	HITS-CLIP	23313552
MIRT693774	hsa-miR-152-3p	HITS-CLIP	23313552
MIRT693773	hsa-miR-1825	HITS-CLIP	23313552
MIRT552948	hsa-miR-5689	HITS-CLIP	23313552
MIRT552945	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT552944	hsa-miR-5583-5p	HITS-CLIP	23313552
MIRT552960	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT552959	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT552958	hsa-miR-1295b-5p	PAR-CLIP	21572407
MIRT552957	hsa-miR-1912	PAR-CLIP	21572407
MIRT552956	hsa-miR-3130-5p	PAR-CLIP	21572407
MIRT552955	hsa-miR-4482-5p	PAR-CLIP	21572407
MIRT552954	hsa-miR-369-3p	PAR-CLIP	21572407
MIRT552953	hsa-miR-5692b	PAR-CLIP	21572407
MIRT552952	hsa-miR-5692c	PAR-CLIP	21572407
MIRT552951	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT552950	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT552949	hsa-miR-586	PAR-CLIP	21572407
MIRT552948	hsa-miR-5689	PAR-CLIP	21572407
MIRT552947	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT552946	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT552945	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT552944	hsa-miR-5583-5p	PAR-CLIP	21572407
MIRT1484312	hsa-miR-106a	CLIP-seq
MIRT1484313	hsa-miR-106b	CLIP-seq
MIRT1484314	hsa-miR-17	CLIP-seq
MIRT1484315	hsa-miR-20a	CLIP-seq
MIRT1484316	hsa-miR-20b	CLIP-seq
MIRT1484317	hsa-miR-3127-3p	CLIP-seq
MIRT1484318	hsa-miR-3609	CLIP-seq
MIRT1484319	hsa-miR-4659a-3p	CLIP-seq
MIRT1484320	hsa-miR-4659b-3p	CLIP-seq
MIRT1484321	hsa-miR-4796-3p	CLIP-seq
MIRT1484322	hsa-miR-519d	CLIP-seq
MIRT1484323	hsa-miR-548ah	CLIP-seq
MIRT1484324	hsa-miR-93	CLIP-seq
MIRT2145786	hsa-miR-3185	CLIP-seq
MIRT2145787	hsa-miR-3612	CLIP-seq
MIRT2145788	hsa-miR-3915	CLIP-seq
MIRT2145789	hsa-miR-3928	CLIP-seq
MIRT2145790	hsa-miR-3929	CLIP-seq
MIRT2145791	hsa-miR-4419b	CLIP-seq
MIRT2145792	hsa-miR-4443	CLIP-seq
MIRT2145793	hsa-miR-4478	CLIP-seq
MIRT2145794	hsa-miR-4710	CLIP-seq
MIRT2145795	hsa-miR-485-5p	CLIP-seq
MIRT2145796	hsa-miR-516b	CLIP-seq
MIRT2145797	hsa-miR-650	CLIP-seq
MIRT2366207	hsa-miR-128	CLIP-seq
MIRT2366208	hsa-miR-2115	CLIP-seq
MIRT2366209	hsa-miR-27a	CLIP-seq
MIRT2366210	hsa-miR-27b	CLIP-seq
MIRT2145787	hsa-miR-3612	CLIP-seq
MIRT2145788	hsa-miR-3915	CLIP-seq
MIRT2145789	hsa-miR-3928	CLIP-seq
MIRT2145790	hsa-miR-3929	CLIP-seq
MIRT2145791	hsa-miR-4419b	CLIP-seq
MIRT2145792	hsa-miR-4443	CLIP-seq
MIRT2145793	hsa-miR-4478	CLIP-seq
MIRT2366211	hsa-miR-455-3p	CLIP-seq
MIRT2145794	hsa-miR-4710	CLIP-seq
MIRT2366212	hsa-miR-4716-5p	CLIP-seq
MIRT2145795	hsa-miR-485-5p	CLIP-seq
MIRT2366213	hsa-miR-513a-5p	CLIP-seq
MIRT2145796	hsa-miR-516b	CLIP-seq
MIRT2145797	hsa-miR-650	CLIP-seq
MIRT2396819	hsa-miR-3154	CLIP-seq
MIRT1484319	hsa-miR-4659a-3p	CLIP-seq
MIRT1484320	hsa-miR-4659b-3p	CLIP-seq
MIRT1484317	hsa-miR-3127-3p	CLIP-seq
MIRT1484319	hsa-miR-4659a-3p	CLIP-seq
MIRT1484320	hsa-miR-4659b-3p	CLIP-seq

Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003713	Function	Transcription coactivator activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0007519	Process	Skeletal muscle tissue development	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA

MIM	HGNC	e!Ensembl
609979	20232	ENSG00000170162

Q8N8G2

Protein name

Transcription cofactor vestigial-like protein 2 (Vgl-2) (Protein VITO1)

Protein function

May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07545	Vg_Tdu	79 → 109	Vestigial/Tondu family	Family

Tissue specificity

TISSUE SPECIFICITY: Skeletal muscle. {ECO:0000269|PubMed:12617818}.

Sequence

MSCLDVMYQVYGPPQPYFAAAYTPYHQKLAYYSKMQEAQECNASPSSSGSGSSSFSSQTP
ASIKEEEGSPEKERPPEAEYINSRCVLFTYFQGDISSVVDEHFSRALSQPSSYSPSCTSS
KAPRSSGPWRDCSFPMSQRSFPASFWNSAYQAPVPPPLGSPLATAHSELPFAAADPYSPA
ALHGHLHQGATEPWHHAHPHHAHPHHPYALGGALGAQAAPYPRPAAVHEVYAPHFDPRYG
PLLMPAASGRPARLATAPAPAPGSPPCELSGKGEPAGAAWAGPGGPFASPSGDVAQGLGL
SVDSARRYSLCGASLLS

Sequence length

317

Interactions

View interactions

VGLL2 (vestigial like family member 2)