Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	2444
Gene name Gene Name - the full gene name approved by the HGNC.	Fyn related Src family tyrosine kinase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FRK
Synonyms (NCBI Gene) Gene synonyms aliases	GTK, PTK5, RAK
Disease Acronyms (UniProt) Disease acronyms from UniProt database	RAK
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q22.1
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018568	hsa-miR-335-5p	Microarray	18185580
MIRT715686	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT715685	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT715684	hsa-miR-5571-3p	HITS-CLIP	19536157
MIRT715682	hsa-miR-7975	HITS-CLIP	19536157
MIRT715683	hsa-miR-4520-3p	HITS-CLIP	19536157
MIRT715681	hsa-miR-384	HITS-CLIP	19536157
MIRT715680	hsa-miR-4520-2-3p	HITS-CLIP	19536157
MIRT715678	hsa-miR-4529-3p	HITS-CLIP	19536157
MIRT715679	hsa-miR-7850-5p	HITS-CLIP	19536157
MIRT658070	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT658069	hsa-miR-1248	HITS-CLIP	23824327
MIRT508174	hsa-miR-3133	PAR-CLIP	20371350
MIRT508173	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT508172	hsa-miR-1243	PAR-CLIP	20371350
MIRT508171	hsa-miR-4499	PAR-CLIP	20371350
MIRT508170	hsa-miR-4463	PAR-CLIP	20371350
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	20371350
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	20371350
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	20371350
MIRT525104	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT525103	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT525102	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT525101	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT525100	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT525099	hsa-miR-4694-3p	PAR-CLIP	22012620
MIRT525098	hsa-miR-224-3p	PAR-CLIP	22012620
MIRT525097	hsa-miR-522-3p	PAR-CLIP	22012620
MIRT525096	hsa-miR-541-5p	PAR-CLIP	22012620
MIRT525095	hsa-miR-4661-5p	PAR-CLIP	22012620
MIRT525094	hsa-miR-3654	PAR-CLIP	22012620
MIRT525093	hsa-miR-3938	PAR-CLIP	22012620
MIRT525092	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT525091	hsa-miR-4738-3p	PAR-CLIP	22012620
MIRT525090	hsa-miR-711	PAR-CLIP	22012620
MIRT525089	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT525088	hsa-miR-3153	PAR-CLIP	22012620
MIRT525087	hsa-miR-6733-5p	PAR-CLIP	22012620
MIRT525086	hsa-miR-6739-5p	PAR-CLIP	22012620
MIRT525085	hsa-miR-4271	PAR-CLIP	22012620
MIRT525084	hsa-miR-4725-3p	PAR-CLIP	22012620
MIRT525083	hsa-miR-6780b-5p	PAR-CLIP	22012620
MIRT525082	hsa-miR-4694-5p	PAR-CLIP	22012620
MIRT525081	hsa-miR-4425	PAR-CLIP	22012620
MIRT525080	hsa-miR-3147	PAR-CLIP	22012620
MIRT525079	hsa-miR-6883-3p	PAR-CLIP	22012620
MIRT525078	hsa-miR-2110	PAR-CLIP	22012620
MIRT525077	hsa-miR-450a-1-3p	PAR-CLIP	22012620
MIRT525076	hsa-miR-8076	PAR-CLIP	22012620
MIRT525075	hsa-miR-3688-3p	PAR-CLIP	22012620
MIRT525074	hsa-miR-103b	PAR-CLIP	22012620
MIRT525073	hsa-miR-4662a-5p	PAR-CLIP	22012620
MIRT525072	hsa-miR-4476	PAR-CLIP	22012620
MIRT525071	hsa-miR-6876-5p	PAR-CLIP	22012620
MIRT525070	hsa-miR-16-2-3p	PAR-CLIP	22012620
MIRT525069	hsa-miR-195-3p	PAR-CLIP	22012620
MIRT525068	hsa-miR-490-5p	PAR-CLIP	22012620
MIRT525067	hsa-miR-6847-3p	PAR-CLIP	22012620
MIRT525066	hsa-miR-5191	PAR-CLIP	22012620
MIRT525065	hsa-miR-4529-5p	PAR-CLIP	22012620
MIRT525064	hsa-miR-3187-3p	PAR-CLIP	22012620
MIRT525063	hsa-miR-8063	PAR-CLIP	22012620
MIRT525062	hsa-miR-4698	PAR-CLIP	22012620
MIRT525061	hsa-miR-4742-5p	PAR-CLIP	22012620
MIRT525060	hsa-miR-4269	PAR-CLIP	22012620
MIRT525059	hsa-miR-6715b-5p	PAR-CLIP	22012620
MIRT525058	hsa-miR-4514	PAR-CLIP	22012620
MIRT525057	hsa-miR-4692	PAR-CLIP	22012620
MIRT525056	hsa-miR-4685-5p	PAR-CLIP	22012620
MIRT525055	hsa-miR-6837-5p	PAR-CLIP	22012620
MIRT525054	hsa-miR-3190-5p	PAR-CLIP	22012620
MIRT525053	hsa-miR-3176	PAR-CLIP	22012620
MIRT525052	hsa-miR-3922-3p	PAR-CLIP	22012620
MIRT525051	hsa-miR-31-5p	PAR-CLIP	22012620
MIRT525050	hsa-miR-503-3p	PAR-CLIP	22012620
MIRT525049	hsa-miR-3671	PAR-CLIP	22012620
MIRT525048	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT525047	hsa-miR-4435	PAR-CLIP	22012620
MIRT525046	hsa-miR-607	PAR-CLIP	22012620
MIRT525045	hsa-miR-4728-3p	PAR-CLIP	22012620
MIRT525044	hsa-miR-105-5p	PAR-CLIP	22012620
MIRT525043	hsa-miR-7853-5p	PAR-CLIP	22012620
MIRT525042	hsa-miR-6761-5p	PAR-CLIP	22012620
MIRT525041	hsa-miR-4663	PAR-CLIP	22012620
MIRT525040	hsa-miR-7160-5p	PAR-CLIP	22012620
MIRT525039	hsa-miR-8077	PAR-CLIP	22012620
MIRT525038	hsa-miR-3646	PAR-CLIP	22012620
MIRT525037	hsa-miR-3974	PAR-CLIP	22012620
MIRT525036	hsa-miR-4436b-3p	PAR-CLIP	22012620
MIRT525035	hsa-miR-4632-5p	PAR-CLIP	22012620
MIRT525034	hsa-miR-6735-5p	PAR-CLIP	22012620
MIRT525033	hsa-miR-6879-5p	PAR-CLIP	22012620
MIRT525032	hsa-miR-7843-5p	PAR-CLIP	22012620
MIRT525031	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT525030	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT525029	hsa-miR-6892-5p	PAR-CLIP	22012620
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508172	hsa-miR-1243	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508166	hsa-miR-1261	PAR-CLIP	23446348
MIRT498512	hsa-miR-4282	PAR-CLIP	24398324
MIRT498511	hsa-miR-6871-5p	PAR-CLIP	24398324
MIRT498509	hsa-miR-4714-3p	PAR-CLIP	24398324
MIRT498510	hsa-miR-6878-5p	PAR-CLIP	24398324
MIRT498508	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT498507	hsa-miR-8085	PAR-CLIP	24398324
MIRT498506	hsa-miR-30c-1-3p	PAR-CLIP	24398324
MIRT498505	hsa-miR-30c-2-3p	PAR-CLIP	24398324
MIRT498504	hsa-miR-6788-5p	PAR-CLIP	24398324
MIRT498503	hsa-miR-450b-5p	PAR-CLIP	24398324
MIRT498502	hsa-miR-507	PAR-CLIP	24398324
MIRT498501	hsa-miR-557	PAR-CLIP	24398324
MIRT498500	hsa-miR-3680-3p	PAR-CLIP	24398324
MIRT498499	hsa-miR-129-5p	PAR-CLIP	24398324
MIRT498498	hsa-miR-6835-3p	PAR-CLIP	24398324
MIRT498497	hsa-miR-4422	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	24398324
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	24398324
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	24398324
MIRT498496	hsa-miR-6871-3p	PAR-CLIP	24398324
MIRT476719	hsa-miR-4519	PAR-CLIP	24398324
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	24398324
MIRT498495	hsa-miR-4302	PAR-CLIP	24398324
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	24398324
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	24398324
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	24398324
MIRT476714	hsa-miR-9-3p	PAR-CLIP	24398324
MIRT476713	hsa-miR-5682	PAR-CLIP	24398324
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT476719	hsa-miR-4519	PAR-CLIP	23592263
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	23592263
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	23592263
MIRT476714	hsa-miR-9-3p	PAR-CLIP	23592263
MIRT476713	hsa-miR-5682	PAR-CLIP	23592263
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	23592263
MIRT715686	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT715685	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT715684	hsa-miR-5571-3p	HITS-CLIP	19536157
MIRT715682	hsa-miR-7975	HITS-CLIP	19536157
MIRT715683	hsa-miR-4520-3p	HITS-CLIP	19536157
MIRT715681	hsa-miR-384	HITS-CLIP	19536157
MIRT715680	hsa-miR-4520-2-3p	HITS-CLIP	19536157
MIRT715678	hsa-miR-4529-3p	HITS-CLIP	19536157
MIRT715679	hsa-miR-7850-5p	HITS-CLIP	19536157
MIRT658070	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT658069	hsa-miR-1248	HITS-CLIP	23824327
MIRT508174	hsa-miR-3133	PAR-CLIP	20371350
MIRT508173	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT508172	hsa-miR-1243	PAR-CLIP	20371350
MIRT508171	hsa-miR-4499	PAR-CLIP	20371350
MIRT508170	hsa-miR-4463	PAR-CLIP	20371350
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	20371350
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	20371350
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	20371350
MIRT525104	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT525103	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT525102	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT525101	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT525100	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT525099	hsa-miR-4694-3p	PAR-CLIP	22012620
MIRT525098	hsa-miR-224-3p	PAR-CLIP	22012620
MIRT525097	hsa-miR-522-3p	PAR-CLIP	22012620
MIRT525096	hsa-miR-541-5p	PAR-CLIP	22012620
MIRT525095	hsa-miR-4661-5p	PAR-CLIP	22012620
MIRT525094	hsa-miR-3654	PAR-CLIP	22012620
MIRT525093	hsa-miR-3938	PAR-CLIP	22012620
MIRT525092	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT525091	hsa-miR-4738-3p	PAR-CLIP	22012620
MIRT525090	hsa-miR-711	PAR-CLIP	22012620
MIRT525089	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT525088	hsa-miR-3153	PAR-CLIP	22012620
MIRT525087	hsa-miR-6733-5p	PAR-CLIP	22012620
MIRT525086	hsa-miR-6739-5p	PAR-CLIP	22012620
MIRT525085	hsa-miR-4271	PAR-CLIP	22012620
MIRT525084	hsa-miR-4725-3p	PAR-CLIP	22012620
MIRT525083	hsa-miR-6780b-5p	PAR-CLIP	22012620
MIRT525082	hsa-miR-4694-5p	PAR-CLIP	22012620
MIRT525081	hsa-miR-4425	PAR-CLIP	22012620
MIRT525080	hsa-miR-3147	PAR-CLIP	22012620
MIRT525079	hsa-miR-6883-3p	PAR-CLIP	22012620
MIRT525078	hsa-miR-2110	PAR-CLIP	22012620
MIRT525077	hsa-miR-450a-1-3p	PAR-CLIP	22012620
MIRT525076	hsa-miR-8076	PAR-CLIP	22012620
MIRT525075	hsa-miR-3688-3p	PAR-CLIP	22012620
MIRT525074	hsa-miR-103b	PAR-CLIP	22012620
MIRT525073	hsa-miR-4662a-5p	PAR-CLIP	22012620
MIRT525072	hsa-miR-4476	PAR-CLIP	22012620
MIRT525071	hsa-miR-6876-5p	PAR-CLIP	22012620
MIRT525070	hsa-miR-16-2-3p	PAR-CLIP	22012620
MIRT525069	hsa-miR-195-3p	PAR-CLIP	22012620
MIRT525068	hsa-miR-490-5p	PAR-CLIP	22012620
MIRT525067	hsa-miR-6847-3p	PAR-CLIP	22012620
MIRT525066	hsa-miR-5191	PAR-CLIP	22012620
MIRT525065	hsa-miR-4529-5p	PAR-CLIP	22012620
MIRT525064	hsa-miR-3187-3p	PAR-CLIP	22012620
MIRT525063	hsa-miR-8063	PAR-CLIP	22012620
MIRT525062	hsa-miR-4698	PAR-CLIP	22012620
MIRT525061	hsa-miR-4742-5p	PAR-CLIP	22012620
MIRT525060	hsa-miR-4269	PAR-CLIP	22012620
MIRT525059	hsa-miR-6715b-5p	PAR-CLIP	22012620
MIRT525058	hsa-miR-4514	PAR-CLIP	22012620
MIRT525057	hsa-miR-4692	PAR-CLIP	22012620
MIRT525056	hsa-miR-4685-5p	PAR-CLIP	22012620
MIRT525055	hsa-miR-6837-5p	PAR-CLIP	22012620
MIRT525054	hsa-miR-3190-5p	PAR-CLIP	22012620
MIRT525053	hsa-miR-3176	PAR-CLIP	22012620
MIRT525052	hsa-miR-3922-3p	PAR-CLIP	22012620
MIRT525051	hsa-miR-31-5p	PAR-CLIP	22012620
MIRT525050	hsa-miR-503-3p	PAR-CLIP	22012620
MIRT525049	hsa-miR-3671	PAR-CLIP	22012620
MIRT525048	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT525047	hsa-miR-4435	PAR-CLIP	22012620
MIRT525046	hsa-miR-607	PAR-CLIP	22012620
MIRT525045	hsa-miR-4728-3p	PAR-CLIP	22012620
MIRT525044	hsa-miR-105-5p	PAR-CLIP	22012620
MIRT525043	hsa-miR-7853-5p	PAR-CLIP	22012620
MIRT525042	hsa-miR-6761-5p	PAR-CLIP	22012620
MIRT525041	hsa-miR-4663	PAR-CLIP	22012620
MIRT525040	hsa-miR-7160-5p	PAR-CLIP	22012620
MIRT525039	hsa-miR-8077	PAR-CLIP	22012620
MIRT525038	hsa-miR-3646	PAR-CLIP	22012620
MIRT525037	hsa-miR-3974	PAR-CLIP	22012620
MIRT525036	hsa-miR-4436b-3p	PAR-CLIP	22012620
MIRT525035	hsa-miR-4632-5p	PAR-CLIP	22012620
MIRT525034	hsa-miR-6735-5p	PAR-CLIP	22012620
MIRT525033	hsa-miR-6879-5p	PAR-CLIP	22012620
MIRT525032	hsa-miR-7843-5p	PAR-CLIP	22012620
MIRT525031	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT525030	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT525029	hsa-miR-6892-5p	PAR-CLIP	22012620
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508172	hsa-miR-1243	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508166	hsa-miR-1261	PAR-CLIP	23446348
MIRT498512	hsa-miR-4282	PAR-CLIP	24398324
MIRT498511	hsa-miR-6871-5p	PAR-CLIP	24398324
MIRT498509	hsa-miR-4714-3p	PAR-CLIP	24398324
MIRT498510	hsa-miR-6878-5p	PAR-CLIP	24398324
MIRT498508	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT498507	hsa-miR-8085	PAR-CLIP	24398324
MIRT498506	hsa-miR-30c-1-3p	PAR-CLIP	24398324
MIRT498505	hsa-miR-30c-2-3p	PAR-CLIP	24398324
MIRT498504	hsa-miR-6788-5p	PAR-CLIP	24398324
MIRT498503	hsa-miR-450b-5p	PAR-CLIP	24398324
MIRT498502	hsa-miR-507	PAR-CLIP	24398324
MIRT498501	hsa-miR-557	PAR-CLIP	24398324
MIRT498500	hsa-miR-3680-3p	PAR-CLIP	24398324
MIRT498499	hsa-miR-129-5p	PAR-CLIP	24398324
MIRT498498	hsa-miR-6835-3p	PAR-CLIP	24398324
MIRT498497	hsa-miR-4422	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	24398324
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	24398324
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	24398324
MIRT498496	hsa-miR-6871-3p	PAR-CLIP	24398324
MIRT476719	hsa-miR-4519	PAR-CLIP	24398324
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	24398324
MIRT498495	hsa-miR-4302	PAR-CLIP	24398324
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	24398324
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	24398324
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	24398324
MIRT476714	hsa-miR-9-3p	PAR-CLIP	24398324
MIRT476713	hsa-miR-5682	PAR-CLIP	24398324
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT476719	hsa-miR-4519	PAR-CLIP	23592263
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	23592263
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	23592263
MIRT476714	hsa-miR-9-3p	PAR-CLIP	23592263
MIRT476713	hsa-miR-5682	PAR-CLIP	23592263
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	23592263
MIRT1004437	hsa-miR-103a	CLIP-seq
MIRT1004438	hsa-miR-107	CLIP-seq
MIRT1004439	hsa-miR-219-5p	CLIP-seq
MIRT1004440	hsa-miR-330-3p	CLIP-seq
MIRT1004441	hsa-miR-370	CLIP-seq
MIRT1004442	hsa-miR-3944-5p	CLIP-seq
MIRT1004443	hsa-miR-4445	CLIP-seq
MIRT1004444	hsa-miR-4724-5p	CLIP-seq
MIRT1004445	hsa-miR-4782-3p	CLIP-seq
MIRT1004446	hsa-miR-4789-3p	CLIP-seq
MIRT1004447	hsa-miR-508-3p	CLIP-seq
MIRT1004448	hsa-miR-514	CLIP-seq
MIRT1004449	hsa-miR-514b-3p	CLIP-seq
MIRT1004450	hsa-miR-545	CLIP-seq
MIRT1004451	hsa-miR-548g	CLIP-seq
MIRT1004452	hsa-miR-642b	CLIP-seq
MIRT1997738	hsa-miR-1237	CLIP-seq
MIRT1997739	hsa-miR-221	CLIP-seq
MIRT1997740	hsa-miR-222	CLIP-seq
MIRT1997741	hsa-miR-2276	CLIP-seq
MIRT1997742	hsa-miR-30a	CLIP-seq
MIRT1997743	hsa-miR-30b	CLIP-seq
MIRT1997744	hsa-miR-30c	CLIP-seq
MIRT1997745	hsa-miR-30d	CLIP-seq
MIRT1997746	hsa-miR-30e	CLIP-seq
MIRT1997747	hsa-miR-3115	CLIP-seq
MIRT1997748	hsa-miR-3662	CLIP-seq
MIRT1997749	hsa-miR-3682-5p	CLIP-seq
MIRT1004442	hsa-miR-3944-5p	CLIP-seq
MIRT1997750	hsa-miR-421	CLIP-seq
MIRT1997751	hsa-miR-4264	CLIP-seq
MIRT1997752	hsa-miR-4330	CLIP-seq
MIRT1997753	hsa-miR-4477a	CLIP-seq
MIRT1997754	hsa-miR-4494	CLIP-seq
MIRT1997755	hsa-miR-4709-5p	CLIP-seq
MIRT1997756	hsa-miR-4772-3p	CLIP-seq
MIRT1997757	hsa-miR-4797-3p	CLIP-seq
MIRT1997758	hsa-miR-499a-5p	CLIP-seq
MIRT1997759	hsa-miR-510	CLIP-seq
MIRT1997760	hsa-miR-512-5p	CLIP-seq
MIRT1997761	hsa-miR-513c	CLIP-seq
MIRT1997762	hsa-miR-514b-5p	CLIP-seq
MIRT1997763	hsa-miR-544	CLIP-seq
MIRT1004450	hsa-miR-545	CLIP-seq
MIRT1997764	hsa-miR-548u	CLIP-seq
MIRT1997765	hsa-miR-548v	CLIP-seq
MIRT2231418	hsa-miR-132	CLIP-seq
MIRT2231419	hsa-miR-212	CLIP-seq
MIRT1997742	hsa-miR-30a	CLIP-seq
MIRT1997743	hsa-miR-30b	CLIP-seq
MIRT1997744	hsa-miR-30c	CLIP-seq
MIRT1997745	hsa-miR-30d	CLIP-seq
MIRT1997746	hsa-miR-30e	CLIP-seq
MIRT1997748	hsa-miR-3662	CLIP-seq
MIRT2231420	hsa-miR-3915	CLIP-seq
MIRT2231421	hsa-miR-3928	CLIP-seq
MIRT1997755	hsa-miR-4709-5p	CLIP-seq
MIRT1997759	hsa-miR-510	CLIP-seq
MIRT1997760	hsa-miR-512-5p	CLIP-seq
MIRT1997764	hsa-miR-548u	CLIP-seq

Show/Hide all(23)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	12837246
GO:0004713	Function	Protein tyrosine kinase activity	EXP	19345329
GO:0004713	Function	Protein tyrosine kinase activity	IBA	21873635
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	IBA	21873635
GO:0005102	Function	Signaling receptor binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	7664264, 19345329, 21516116, 25416956, 31515488, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005622	Component	Intracellular anatomical structure	TAS	7510261
GO:0005634	Component	Nucleus	TAS	7696183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006468	Process	Protein phosphorylation	TAS	7696183
GO:0007169	Process	Transmembrane receptor protein tyrosine kinase signaling pathway	IBA	21873635
GO:0008285	Process	Negative regulation of cell population proliferation	TAS	7664264
GO:0030154	Process	Cell differentiation	IBA	21873635
GO:0031234	Component	Extrinsic component of cytoplasmic side of plasma membrane	IBA	21873635
GO:0035578	Component	Azurophil granule lumen	TAS
GO:0035580	Component	Specific granule lumen	TAS
GO:0043312	Process	Neutrophil degranulation	TAS
GO:0045087	Process	Innate immune response	IBA	21873635
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145

MIM	HGNC	e!Ensembl
606573	3955	ENSG00000111816

Protein

UniProt ID

P42685

Protein name

Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)

Protein function

Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by r

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00018	SH3_1	48 → 102	SH3 domain	Domain
PF00017	SH2	116 → 193	SH2 domain	Domain
PF07714	PK_Tyr_Ser-Thr	234 → 487	Protein tyrosine and serine/threonine kinase	Domain

Tissue specificity

TISSUE SPECIFICITY: Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon. {ECO:0000269|PubMed:7696183}.

Sequence

MSNICQRLWEYLEPYLPCLSTEADKSTVIENPGALCSPQSQRHGHYFVALFDYQARTAED
LSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGA
IGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFFLTRR
RIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRL
GSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLED
PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNV
LVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFG
ILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTF
ETLRWKLEDYFETDSSYSDANNFIR

Sequence length

505

Interactions

View interactions

	Reactome
			Neutrophil degranulation Regulation of PTEN stability and activity

Show/Hide Unknown Diseases (3)

Disease term	Disease name	Source
Unknown
Metabolic Syndrome	Metabolic Syndrome	GWAS
Gout	Gout	GWAS
Fibromuscular Dysplasia	Fibromuscular Dysplasia	GWAS

Show/Hide Text Mining Associations (17)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	26519433
Bornholm Eye Disease	Associate	33922358
Breast Neoplasms	Associate	20057140, 9729531
Breast Neoplasms	Inhibit	28077797, 31681835
Carcinoma Non Small Cell Lung	Associate	25783528
Carcinoma Pancreatic Ductal	Associate	33213062
Carcinoma Renal Cell	Associate	31883420
Colorectal Neoplasms	Associate	34888857
Diabetes Mellitus Type 1	Associate	20057140
Glioblastoma	Inhibit	35723276
Glioma	Associate	28077797, 35723276
Lown Ganong Levine Syndrome	Associate	32710281
Neoplasms	Associate	20057140
Neoplasms	Inhibit	28077797, 35723276
Osteoarthritis	Associate	33435956
Pancreatic Neoplasms	Associate	33213062
Prostatic Neoplasms	Associate	25472581

FRK (fyn related Src family tyrosine kinase)