FRK (fyn related Src family tyrosine kinase)

Gene

• Entrez ID: 2444
• Gene name: Fyn related Src family tyrosine kinase
• Gene symbol: FRK
• Synonyms (NCBI Gene): GTK, PTK5, RAK
• Chromosome: 6
• Chromosome location: 6q22.1
• Summary: The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018568	hsa-miR-335-5p	Microarray	18185580
MIRT715686	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT715685	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT715684	hsa-miR-5571-3p	HITS-CLIP	19536157
MIRT715682	hsa-miR-7975	HITS-CLIP	19536157
MIRT715683	hsa-miR-4520-3p	HITS-CLIP	19536157
MIRT715681	hsa-miR-384	HITS-CLIP	19536157
MIRT715680	hsa-miR-4520-2-3p	HITS-CLIP	19536157
MIRT715678	hsa-miR-4529-3p	HITS-CLIP	19536157
MIRT715679	hsa-miR-7850-5p	HITS-CLIP	19536157
MIRT658070	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT658069	hsa-miR-1248	HITS-CLIP	23824327
MIRT508174	hsa-miR-3133	PAR-CLIP	20371350
MIRT508173	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT508172	hsa-miR-1243	PAR-CLIP	20371350
MIRT508171	hsa-miR-4499	PAR-CLIP	20371350
MIRT508170	hsa-miR-4463	PAR-CLIP	20371350
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	20371350
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	20371350
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	20371350
MIRT525104	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT525103	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT525102	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT525101	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT525100	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT525099	hsa-miR-4694-3p	PAR-CLIP	22012620
MIRT525098	hsa-miR-224-3p	PAR-CLIP	22012620
MIRT525097	hsa-miR-522-3p	PAR-CLIP	22012620
MIRT525096	hsa-miR-541-5p	PAR-CLIP	22012620
MIRT525095	hsa-miR-4661-5p	PAR-CLIP	22012620
MIRT525094	hsa-miR-3654	PAR-CLIP	22012620
MIRT525093	hsa-miR-3938	PAR-CLIP	22012620
MIRT525092	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT525091	hsa-miR-4738-3p	PAR-CLIP	22012620
MIRT525090	hsa-miR-711	PAR-CLIP	22012620
MIRT525089	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT525088	hsa-miR-3153	PAR-CLIP	22012620
MIRT525087	hsa-miR-6733-5p	PAR-CLIP	22012620
MIRT525086	hsa-miR-6739-5p	PAR-CLIP	22012620
MIRT525085	hsa-miR-4271	PAR-CLIP	22012620
MIRT525084	hsa-miR-4725-3p	PAR-CLIP	22012620
MIRT525083	hsa-miR-6780b-5p	PAR-CLIP	22012620
MIRT525082	hsa-miR-4694-5p	PAR-CLIP	22012620
MIRT525081	hsa-miR-4425	PAR-CLIP	22012620
MIRT525080	hsa-miR-3147	PAR-CLIP	22012620
MIRT525079	hsa-miR-6883-3p	PAR-CLIP	22012620
MIRT525078	hsa-miR-2110	PAR-CLIP	22012620
MIRT525077	hsa-miR-450a-1-3p	PAR-CLIP	22012620
MIRT525076	hsa-miR-8076	PAR-CLIP	22012620
MIRT525075	hsa-miR-3688-3p	PAR-CLIP	22012620
MIRT525074	hsa-miR-103b	PAR-CLIP	22012620
MIRT525073	hsa-miR-4662a-5p	PAR-CLIP	22012620
MIRT525072	hsa-miR-4476	PAR-CLIP	22012620
MIRT525071	hsa-miR-6876-5p	PAR-CLIP	22012620
MIRT525070	hsa-miR-16-2-3p	PAR-CLIP	22012620
MIRT525069	hsa-miR-195-3p	PAR-CLIP	22012620
MIRT525068	hsa-miR-490-5p	PAR-CLIP	22012620
MIRT525067	hsa-miR-6847-3p	PAR-CLIP	22012620
MIRT525066	hsa-miR-5191	PAR-CLIP	22012620
MIRT525065	hsa-miR-4529-5p	PAR-CLIP	22012620
MIRT525064	hsa-miR-3187-3p	PAR-CLIP	22012620
MIRT525063	hsa-miR-8063	PAR-CLIP	22012620
MIRT525062	hsa-miR-4698	PAR-CLIP	22012620
MIRT525061	hsa-miR-4742-5p	PAR-CLIP	22012620
MIRT525060	hsa-miR-4269	PAR-CLIP	22012620
MIRT525059	hsa-miR-6715b-5p	PAR-CLIP	22012620
MIRT525058	hsa-miR-4514	PAR-CLIP	22012620
MIRT525057	hsa-miR-4692	PAR-CLIP	22012620
MIRT525056	hsa-miR-4685-5p	PAR-CLIP	22012620
MIRT525055	hsa-miR-6837-5p	PAR-CLIP	22012620
MIRT525054	hsa-miR-3190-5p	PAR-CLIP	22012620
MIRT525053	hsa-miR-3176	PAR-CLIP	22012620
MIRT525052	hsa-miR-3922-3p	PAR-CLIP	22012620
MIRT525051	hsa-miR-31-5p	PAR-CLIP	22012620
MIRT525050	hsa-miR-503-3p	PAR-CLIP	22012620
MIRT525049	hsa-miR-3671	PAR-CLIP	22012620
MIRT525048	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT525047	hsa-miR-4435	PAR-CLIP	22012620
MIRT525046	hsa-miR-607	PAR-CLIP	22012620
MIRT525045	hsa-miR-4728-3p	PAR-CLIP	22012620
MIRT525044	hsa-miR-105-5p	PAR-CLIP	22012620
MIRT525043	hsa-miR-7853-5p	PAR-CLIP	22012620
MIRT525042	hsa-miR-6761-5p	PAR-CLIP	22012620
MIRT525041	hsa-miR-4663	PAR-CLIP	22012620
MIRT525040	hsa-miR-7160-5p	PAR-CLIP	22012620
MIRT525039	hsa-miR-8077	PAR-CLIP	22012620
MIRT525038	hsa-miR-3646	PAR-CLIP	22012620
MIRT525037	hsa-miR-3974	PAR-CLIP	22012620
MIRT525036	hsa-miR-4436b-3p	PAR-CLIP	22012620
MIRT525035	hsa-miR-4632-5p	PAR-CLIP	22012620
MIRT525034	hsa-miR-6735-5p	PAR-CLIP	22012620
MIRT525033	hsa-miR-6879-5p	PAR-CLIP	22012620
MIRT525032	hsa-miR-7843-5p	PAR-CLIP	22012620
MIRT525031	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT525030	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT525029	hsa-miR-6892-5p	PAR-CLIP	22012620
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508172	hsa-miR-1243	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508166	hsa-miR-1261	PAR-CLIP	23446348
MIRT498512	hsa-miR-4282	PAR-CLIP	24398324
MIRT498511	hsa-miR-6871-5p	PAR-CLIP	24398324
MIRT498509	hsa-miR-4714-3p	PAR-CLIP	24398324
MIRT498510	hsa-miR-6878-5p	PAR-CLIP	24398324
MIRT498508	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT498507	hsa-miR-8085	PAR-CLIP	24398324
MIRT498506	hsa-miR-30c-1-3p	PAR-CLIP	24398324
MIRT498505	hsa-miR-30c-2-3p	PAR-CLIP	24398324
MIRT498504	hsa-miR-6788-5p	PAR-CLIP	24398324
MIRT498503	hsa-miR-450b-5p	PAR-CLIP	24398324
MIRT498502	hsa-miR-507	PAR-CLIP	24398324
MIRT498501	hsa-miR-557	PAR-CLIP	24398324
MIRT498500	hsa-miR-3680-3p	PAR-CLIP	24398324
MIRT498499	hsa-miR-129-5p	PAR-CLIP	24398324
MIRT498498	hsa-miR-6835-3p	PAR-CLIP	24398324
MIRT498497	hsa-miR-4422	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	24398324
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	24398324
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	24398324
MIRT498496	hsa-miR-6871-3p	PAR-CLIP	24398324
MIRT476719	hsa-miR-4519	PAR-CLIP	24398324
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	24398324
MIRT498495	hsa-miR-4302	PAR-CLIP	24398324
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	24398324
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	24398324
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	24398324
MIRT476714	hsa-miR-9-3p	PAR-CLIP	24398324
MIRT476713	hsa-miR-5682	PAR-CLIP	24398324
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT476719	hsa-miR-4519	PAR-CLIP	23592263
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	23592263
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	23592263
MIRT476714	hsa-miR-9-3p	PAR-CLIP	23592263
MIRT476713	hsa-miR-5682	PAR-CLIP	23592263
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	23592263
MIRT715686	hsa-miR-6819-3p	HITS-CLIP	19536157
MIRT715685	hsa-miR-6877-3p	HITS-CLIP	19536157
MIRT715684	hsa-miR-5571-3p	HITS-CLIP	19536157
MIRT715682	hsa-miR-7975	HITS-CLIP	19536157
MIRT715683	hsa-miR-4520-3p	HITS-CLIP	19536157
MIRT715681	hsa-miR-384	HITS-CLIP	19536157
MIRT715680	hsa-miR-4520-2-3p	HITS-CLIP	19536157
MIRT715678	hsa-miR-4529-3p	HITS-CLIP	19536157
MIRT715679	hsa-miR-7850-5p	HITS-CLIP	19536157
MIRT658070	hsa-miR-1237-3p	HITS-CLIP	23824327
MIRT658069	hsa-miR-1248	HITS-CLIP	23824327
MIRT508174	hsa-miR-3133	PAR-CLIP	20371350
MIRT508173	hsa-miR-186-5p	PAR-CLIP	20371350
MIRT508172	hsa-miR-1243	PAR-CLIP	20371350
MIRT508171	hsa-miR-4499	PAR-CLIP	20371350
MIRT508170	hsa-miR-4463	PAR-CLIP	20371350
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	20371350
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	20371350
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	20371350
MIRT525104	hsa-miR-548a-3p	PAR-CLIP	22012620
MIRT525103	hsa-miR-548ar-3p	PAR-CLIP	22012620
MIRT525102	hsa-miR-548az-3p	PAR-CLIP	22012620
MIRT525101	hsa-miR-548e-3p	PAR-CLIP	22012620
MIRT525100	hsa-miR-548f-3p	PAR-CLIP	22012620
MIRT525099	hsa-miR-4694-3p	PAR-CLIP	22012620
MIRT525098	hsa-miR-224-3p	PAR-CLIP	22012620
MIRT525097	hsa-miR-522-3p	PAR-CLIP	22012620
MIRT525096	hsa-miR-541-5p	PAR-CLIP	22012620
MIRT525095	hsa-miR-4661-5p	PAR-CLIP	22012620
MIRT525094	hsa-miR-3654	PAR-CLIP	22012620
MIRT525093	hsa-miR-3938	PAR-CLIP	22012620
MIRT525092	hsa-miR-454-5p	PAR-CLIP	22012620
MIRT525091	hsa-miR-4738-3p	PAR-CLIP	22012620
MIRT525090	hsa-miR-711	PAR-CLIP	22012620
MIRT525089	hsa-miR-4668-5p	PAR-CLIP	22012620
MIRT525088	hsa-miR-3153	PAR-CLIP	22012620
MIRT525087	hsa-miR-6733-5p	PAR-CLIP	22012620
MIRT525086	hsa-miR-6739-5p	PAR-CLIP	22012620
MIRT525085	hsa-miR-4271	PAR-CLIP	22012620
MIRT525084	hsa-miR-4725-3p	PAR-CLIP	22012620
MIRT525083	hsa-miR-6780b-5p	PAR-CLIP	22012620
MIRT525082	hsa-miR-4694-5p	PAR-CLIP	22012620
MIRT525081	hsa-miR-4425	PAR-CLIP	22012620
MIRT525080	hsa-miR-3147	PAR-CLIP	22012620
MIRT525079	hsa-miR-6883-3p	PAR-CLIP	22012620
MIRT525078	hsa-miR-2110	PAR-CLIP	22012620
MIRT525077	hsa-miR-450a-1-3p	PAR-CLIP	22012620
MIRT525076	hsa-miR-8076	PAR-CLIP	22012620
MIRT525075	hsa-miR-3688-3p	PAR-CLIP	22012620
MIRT525074	hsa-miR-103b	PAR-CLIP	22012620
MIRT525073	hsa-miR-4662a-5p	PAR-CLIP	22012620
MIRT525072	hsa-miR-4476	PAR-CLIP	22012620
MIRT525071	hsa-miR-6876-5p	PAR-CLIP	22012620
MIRT525070	hsa-miR-16-2-3p	PAR-CLIP	22012620
MIRT525069	hsa-miR-195-3p	PAR-CLIP	22012620
MIRT525068	hsa-miR-490-5p	PAR-CLIP	22012620
MIRT525067	hsa-miR-6847-3p	PAR-CLIP	22012620
MIRT525066	hsa-miR-5191	PAR-CLIP	22012620
MIRT525065	hsa-miR-4529-5p	PAR-CLIP	22012620
MIRT525064	hsa-miR-3187-3p	PAR-CLIP	22012620
MIRT525063	hsa-miR-8063	PAR-CLIP	22012620
MIRT525062	hsa-miR-4698	PAR-CLIP	22012620
MIRT525061	hsa-miR-4742-5p	PAR-CLIP	22012620
MIRT525060	hsa-miR-4269	PAR-CLIP	22012620
MIRT525059	hsa-miR-6715b-5p	PAR-CLIP	22012620
MIRT525058	hsa-miR-4514	PAR-CLIP	22012620
MIRT525057	hsa-miR-4692	PAR-CLIP	22012620
MIRT525056	hsa-miR-4685-5p	PAR-CLIP	22012620
MIRT525055	hsa-miR-6837-5p	PAR-CLIP	22012620
MIRT525054	hsa-miR-3190-5p	PAR-CLIP	22012620
MIRT525053	hsa-miR-3176	PAR-CLIP	22012620
MIRT525052	hsa-miR-3922-3p	PAR-CLIP	22012620
MIRT525051	hsa-miR-31-5p	PAR-CLIP	22012620
MIRT525050	hsa-miR-503-3p	PAR-CLIP	22012620
MIRT525049	hsa-miR-3671	PAR-CLIP	22012620
MIRT525048	hsa-miR-488-3p	PAR-CLIP	22012620
MIRT525047	hsa-miR-4435	PAR-CLIP	22012620
MIRT525046	hsa-miR-607	PAR-CLIP	22012620
MIRT525045	hsa-miR-4728-3p	PAR-CLIP	22012620
MIRT525044	hsa-miR-105-5p	PAR-CLIP	22012620
MIRT525043	hsa-miR-7853-5p	PAR-CLIP	22012620
MIRT525042	hsa-miR-6761-5p	PAR-CLIP	22012620
MIRT525041	hsa-miR-4663	PAR-CLIP	22012620
MIRT525040	hsa-miR-7160-5p	PAR-CLIP	22012620
MIRT525039	hsa-miR-8077	PAR-CLIP	22012620
MIRT525038	hsa-miR-3646	PAR-CLIP	22012620
MIRT525037	hsa-miR-3974	PAR-CLIP	22012620
MIRT525036	hsa-miR-4436b-3p	PAR-CLIP	22012620
MIRT525035	hsa-miR-4632-5p	PAR-CLIP	22012620
MIRT525034	hsa-miR-6735-5p	PAR-CLIP	22012620
MIRT525033	hsa-miR-6879-5p	PAR-CLIP	22012620
MIRT525032	hsa-miR-7843-5p	PAR-CLIP	22012620
MIRT525031	hsa-miR-6730-5p	PAR-CLIP	22012620
MIRT525030	hsa-miR-203a-3p	PAR-CLIP	22012620
MIRT525029	hsa-miR-6892-5p	PAR-CLIP	22012620
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508174	hsa-miR-3133	PAR-CLIP	23446348
MIRT508173	hsa-miR-186-5p	PAR-CLIP	23446348
MIRT508172	hsa-miR-1243	PAR-CLIP	23446348
MIRT508171	hsa-miR-4499	PAR-CLIP	23446348
MIRT508170	hsa-miR-4463	PAR-CLIP	23446348
MIRT508169	hsa-miR-3688-5p	PAR-CLIP	23446348
MIRT508168	hsa-miR-891a-3p	PAR-CLIP	23446348
MIRT508167	hsa-miR-151a-3p	PAR-CLIP	23446348
MIRT508166	hsa-miR-1261	PAR-CLIP	23446348
MIRT498512	hsa-miR-4282	PAR-CLIP	24398324
MIRT498511	hsa-miR-6871-5p	PAR-CLIP	24398324
MIRT498509	hsa-miR-4714-3p	PAR-CLIP	24398324
MIRT498510	hsa-miR-6878-5p	PAR-CLIP	24398324
MIRT498508	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT498507	hsa-miR-8085	PAR-CLIP	24398324
MIRT498506	hsa-miR-30c-1-3p	PAR-CLIP	24398324
MIRT498505	hsa-miR-30c-2-3p	PAR-CLIP	24398324
MIRT498504	hsa-miR-6788-5p	PAR-CLIP	24398324
MIRT498503	hsa-miR-450b-5p	PAR-CLIP	24398324
MIRT498502	hsa-miR-507	PAR-CLIP	24398324
MIRT498501	hsa-miR-557	PAR-CLIP	24398324
MIRT498500	hsa-miR-3680-3p	PAR-CLIP	24398324
MIRT498499	hsa-miR-129-5p	PAR-CLIP	24398324
MIRT498498	hsa-miR-6835-3p	PAR-CLIP	24398324
MIRT498497	hsa-miR-4422	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	24398324
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	24398324
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	24398324
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	24398324
MIRT498496	hsa-miR-6871-3p	PAR-CLIP	24398324
MIRT476719	hsa-miR-4519	PAR-CLIP	24398324
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	24398324
MIRT498495	hsa-miR-4302	PAR-CLIP	24398324
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	24398324
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	24398324
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	24398324
MIRT476714	hsa-miR-9-3p	PAR-CLIP	24398324
MIRT476713	hsa-miR-5682	PAR-CLIP	24398324
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	24398324
MIRT476723	hsa-miR-6873-5p	PAR-CLIP	23592263
MIRT476722	hsa-miR-29a-3p	PAR-CLIP	23592263
MIRT476721	hsa-miR-29b-3p	PAR-CLIP	23592263
MIRT476720	hsa-miR-29c-3p	PAR-CLIP	23592263
MIRT476719	hsa-miR-4519	PAR-CLIP	23592263
MIRT476718	hsa-miR-5584-5p	PAR-CLIP	23592263
MIRT476717	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT476715	hsa-miR-6832-5p	PAR-CLIP	23592263
MIRT476716	hsa-miR-4732-5p	PAR-CLIP	23592263
MIRT476714	hsa-miR-9-3p	PAR-CLIP	23592263
MIRT476713	hsa-miR-5682	PAR-CLIP	23592263
MIRT476712	hsa-miR-6867-5p	PAR-CLIP	23592263
MIRT1004437	hsa-miR-103a	CLIP-seq
MIRT1004438	hsa-miR-107	CLIP-seq
MIRT1004439	hsa-miR-219-5p	CLIP-seq
MIRT1004440	hsa-miR-330-3p	CLIP-seq
MIRT1004441	hsa-miR-370	CLIP-seq
MIRT1004442	hsa-miR-3944-5p	CLIP-seq
MIRT1004443	hsa-miR-4445	CLIP-seq
MIRT1004444	hsa-miR-4724-5p	CLIP-seq
MIRT1004445	hsa-miR-4782-3p	CLIP-seq
MIRT1004446	hsa-miR-4789-3p	CLIP-seq
MIRT1004447	hsa-miR-508-3p	CLIP-seq
MIRT1004448	hsa-miR-514	CLIP-seq
MIRT1004449	hsa-miR-514b-3p	CLIP-seq
MIRT1004450	hsa-miR-545	CLIP-seq
MIRT1004451	hsa-miR-548g	CLIP-seq
MIRT1004452	hsa-miR-642b	CLIP-seq
MIRT1997738	hsa-miR-1237	CLIP-seq
MIRT1997739	hsa-miR-221	CLIP-seq
MIRT1997740	hsa-miR-222	CLIP-seq
MIRT1997741	hsa-miR-2276	CLIP-seq
MIRT1997742	hsa-miR-30a	CLIP-seq
MIRT1997743	hsa-miR-30b	CLIP-seq
MIRT1997744	hsa-miR-30c	CLIP-seq
MIRT1997745	hsa-miR-30d	CLIP-seq
MIRT1997746	hsa-miR-30e	CLIP-seq
MIRT1997747	hsa-miR-3115	CLIP-seq
MIRT1997748	hsa-miR-3662	CLIP-seq
MIRT1997749	hsa-miR-3682-5p	CLIP-seq
MIRT1004442	hsa-miR-3944-5p	CLIP-seq
MIRT1997750	hsa-miR-421	CLIP-seq
MIRT1997751	hsa-miR-4264	CLIP-seq
MIRT1997752	hsa-miR-4330	CLIP-seq
MIRT1997753	hsa-miR-4477a	CLIP-seq
MIRT1997754	hsa-miR-4494	CLIP-seq
MIRT1997755	hsa-miR-4709-5p	CLIP-seq
MIRT1997756	hsa-miR-4772-3p	CLIP-seq
MIRT1997757	hsa-miR-4797-3p	CLIP-seq
MIRT1997758	hsa-miR-499a-5p	CLIP-seq
MIRT1997759	hsa-miR-510	CLIP-seq
MIRT1997760	hsa-miR-512-5p	CLIP-seq
MIRT1997761	hsa-miR-513c	CLIP-seq
MIRT1997762	hsa-miR-514b-5p	CLIP-seq
MIRT1997763	hsa-miR-544	CLIP-seq
MIRT1004450	hsa-miR-545	CLIP-seq
MIRT1997764	hsa-miR-548u	CLIP-seq
MIRT1997765	hsa-miR-548v	CLIP-seq
MIRT2231418	hsa-miR-132	CLIP-seq
MIRT2231419	hsa-miR-212	CLIP-seq
MIRT1997742	hsa-miR-30a	CLIP-seq
MIRT1997743	hsa-miR-30b	CLIP-seq
MIRT1997744	hsa-miR-30c	CLIP-seq
MIRT1997745	hsa-miR-30d	CLIP-seq
MIRT1997746	hsa-miR-30e	CLIP-seq
MIRT1997748	hsa-miR-3662	CLIP-seq
MIRT2231420	hsa-miR-3915	CLIP-seq
MIRT2231421	hsa-miR-3928	CLIP-seq
MIRT1997755	hsa-miR-4709-5p	CLIP-seq
MIRT1997759	hsa-miR-510	CLIP-seq
MIRT1997760	hsa-miR-512-5p	CLIP-seq
MIRT1997764	hsa-miR-548u	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	12837246
GO:0000166	Function	Nucleotide binding	IEA
GO:0002221	Process	Pattern recognition receptor signaling pathway	IDA	23910378
GO:0002753	Process	Cytoplasmic pattern recognition receptor signaling pathway	IDA	29441066
GO:0004672	Function	Protein kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	EXP	19345329
GO:0004713	Function	Protein tyrosine kinase activity	IDA	35723276
GO:0004713	Function	Protein tyrosine kinase activity	IEA
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	IBA
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	IEA
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	TAS	7510261
GO:0005102	Function	Signaling receptor binding	IBA
GO:0005515	Function	Protein binding	IPI	7664264, 19345329, 21516116, 25416956, 31515488, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	7696183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	7696183
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0007169	Process	Cell surface receptor protein tyrosine kinase signaling pathway	IBA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030154	Process	Cell differentiation	IBA
GO:0030154	Process	Cell differentiation	IEA
GO:0035578	Component	Azurophil granule lumen	TAS
GO:0035580	Component	Specific granule lumen	TAS
GO:0039537	Process	Symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway	IDA	34811497
GO:0045824	Process	Negative regulation of innate immune response	IDA	34811497
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145

Other IDs

• MIM: 606573
• HGNC: 3955
• e!Ensembl: ENSG00000111816

Protein

• UniProt ID: P42685
• Protein name: Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5)
• Protein function: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by r
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00018	SH3_1	48 → 102	SH3 domain	Domain
  PF00017	SH2	116 → 193	SH2 domain	Domain
  PF07714	PK_Tyr_Ser-Thr	234 → 487	Protein tyrosine and serine/threonine kinase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon. {ECO:0000269|PubMed:7696183}.
• Sequence:

  MSNICQRLWEYLEPYLPCLSTEADKSTVIENPGALCSPQSQRHGHYFVALFDYQARTAED
  LSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGA
  IGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFFLTRR
  RIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRL
  GSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLED
  PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNV
  LVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFG
  ILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTF
  ETLRWKLEDYFETDSSYSDANNFIR

• Sequence length: 505

Pathways

Reactome:

Neutrophil degranulation
Regulation of PTEN stability and activity

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Craniofacial microsomia 1	Uncertain significance	rs764595423	RCV001507328

Associations from Text Mining
Disease Name	Relationship Type	References
Alzheimer Disease	Associate	26519433
Bornholm Eye Disease	Associate	33922358
Breast Neoplasms	Associate	20057140, 9729531
Breast Neoplasms	Inhibit	28077797, 31681835
Carcinoma Non Small Cell Lung	Associate	25783528
Carcinoma Pancreatic Ductal	Associate	33213062
Carcinoma Renal Cell	Associate	31883420
Colorectal Neoplasms	Associate	34888857
Diabetes Mellitus Type 1	Associate	20057140
Glioblastoma	Inhibit	35723276
Glioma	Associate	28077797, 35723276
Lown Ganong Levine Syndrome	Associate	32710281
Neoplasms	Associate	20057140
Neoplasms	Inhibit	28077797, 35723276
Osteoarthritis	Associate	33435956
Pancreatic Neoplasms	Associate	33213062
Prostatic Neoplasms	Associate	25472581