Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23780
Gene name Gene Name - the full gene name approved by the HGNC.
Apolipoprotein L2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
APOL2
Synonyms (NCBI Gene) Gene synonyms aliases
APOL-II, APOL3
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q12.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles. Two transcript variants encoding the same protein have been
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017248 hsa-miR-335-5p Microarray 18185580
MIRT024143 hsa-miR-221-3p Sequencing 20371350
MIRT025355 hsa-miR-34a-5p Proteomics 21566225
MIRT671855 hsa-miR-4755-3p HITS-CLIP 23824327
MIRT671854 hsa-miR-4284 HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005102 Function Signaling receptor binding NAS 11374903
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
GO:0005789 Component Endoplasmic reticulum membrane NAS 11374903
GO:0006629 Process Lipid metabolic process NAS 11374903, 11944986
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607252 619 ENSG00000128335
Protein
UniProt ID Q9BQE5
Protein name Apolipoprotein L2 (Apolipoprotein L-II) (ApoL-II)
Protein function May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
PDB 7LF8
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05461 ApoL 19 331 Apolipoprotein L Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed; the highest levels are found in lung, thymus, pancreas, placenta, adult brain and prostate; also detected in spleen, liver, kidney, colon, small intestine, uterus, spinal cord, adrenal gland, salivary gland, trachea,
Sequence
Sequence length 337
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
Associations from Text Mining
Disease Name Relationship Type References
Anxiety Associate 38051303
Depressive Disorder Associate 38051303
Diabetes Mellitus Associate 24385048
Diabetes Mellitus Type 2 Associate 24385048
Inflammation Associate 37924378
Irritable Bowel Syndrome Associate 28191693
Kidney Diseases Associate 24385048
Kidney Failure Chronic Associate 24385048
Lymphatic Metastasis Associate 30082491
Ovarian Neoplasms Associate 20132413