Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23635
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Single stranded DNA binding protein 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SSBP2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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HSPC116, SOSS-B2 |
Chromosome
Chromosome number
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5 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q14.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene ma |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Glioblastoma |
Glioblastoma, Glioblastoma Multiforme |
rs121913500, rs886042842, rs1555138291, rs1558518449, rs1567176006, rs1558650888 |
22472174 |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
18559593 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Anorexia |
Anorexia |
|
|
GWAS |
Bipolar Disorder |
Bipolar Disorder |
|
|
GWAS |
Metabolic Syndrome |
Metabolic Syndrome |
|
|
GWAS |
Breast Cancer |
Breast Cancer |
Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients |
|
GWAS, CBGDA |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Breast Neoplasms |
Associate
|
25824743 |
Cakut |
Associate
|
40774958 |
Carcinoma Hepatocellular |
Associate
|
30541499 |
Carcinoma Renal Cell |
Inhibit
|
31882468 |
Cholecystitis |
Associate
|
25066711 |
Esophageal Squamous Cell Carcinoma |
Inhibit
|
20658532, 30541499 |
Gallbladder Neoplasms |
Associate
|
25066711, 30541499 |
Glioblastoma |
Associate
|
22472174, 30541499 |
Hematologic Neoplasms |
Inhibit
|
30541499 |
Leukemia Myeloid Acute |
Associate
|
35412941 |
Neoplasms |
Inhibit
|
20658532, 24346345, 25760242, 30541499, 31882468, 32745119 |
Neoplasms |
Associate
|
22472174, 23125005 |
Ovarian Neoplasms |
Inhibit
|
30541499 |
Pancreatic Neoplasms |
Associate
|
21347333, 22820136 |
Peritonitis |
Associate
|
31332257 |
Precursor T Cell Lymphoblastic Leukemia Lymphoma |
Associate
|
24367274 |
Prostatic Neoplasms |
Inhibit
|
18559593, 30541499 |
Prostatic Neoplasms |
Associate
|
24769028 |
Stomach Neoplasms |
Associate
|
32745119 |
|