Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23597
Gene name Gene Name - the full gene name approved by the HGNC.
Acyl-CoA thioesterase 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ACOT9
Synonyms (NCBI Gene) Gene synonyms aliases
ACATE2, CGI-16, MT-ACT48, MTACT48
Chromosome Chromosome number
X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
Xp22.11
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a mitochondrial acyl-CoA thioesterase of unknown function. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT041228 hsa-miR-193b-3p CLASH 23622248
MIRT039370 hsa-miR-421 CLASH 23622248
MIRT706221 hsa-miR-6514-5p HITS-CLIP 22927820
MIRT706220 hsa-miR-500b-3p HITS-CLIP 22927820
MIRT706219 hsa-miR-5693 HITS-CLIP 22927820
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003986 Function Acetyl-CoA hydrolase activity ISS
GO:0005739 Component Mitochondrion IBA 21873635
GO:0005739 Component Mitochondrion ISS
GO:0005759 Component Mitochondrial matrix TAS
GO:0006637 Process Acyl-CoA metabolic process IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
300862 17152 ENSG00000123130
Protein
UniProt ID Q9Y305
Protein name Acyl-coenzyme A thioesterase 9, mitochondrial (Acyl-CoA thioesterase 9) (EC 3.1.2.-) (EC 3.1.2.2) (Acyl-CoA thioester hydrolase 9)
Protein function Mitochondrial acyl-CoA thioesterase. Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoA), regulating their respective intracellular levels. Regulates both mitochondrial lipid and amino acid metabolism. {ECO:0000250|U
Family and domains
Sequence
MRRAALRLCALGKGQLTPGRGLTQGPQNPKKQGIFHIHEVRDKLREIVGASTNWRDHVKA
MEERKLLHSFLAKSQDGLPPRRMKDSYIEVLLPLGSEPELREKYLTVQNTVRFGRILEDL
DSLGVLICYMHNKIHSAKMSPLSIVTALVDKIDMCKKSLSPEQDIKFSGHVSWVGKTSME
VKMQMFQLHGDEFCPVLDATFVMVARDSENKGPAFVNPLIPESPEEEELFRQGELNKGRR
IAFSSTSLLKMAPSAEERTTIHEMFLSTLDPKTISFRSRVLPSNAVWMENSKLKSLEICH
PQERNIFNRIFGGFLMRKAYELAWATACSFGGSRPFVVAVDDIMFQKPVEVGSLLFLSSQ
VCFTQNNYIQVRVHSEVASLQEKQHTTTNVFHFTFMSEKEVPLVFPKTYGESMLYLDGQR
HFNSMSGPATLRKDYLVEP
Sequence length 439
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Mitochondrial Fatty Acid Beta-Oxidation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Mental retardation Intellectual Disability rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315
View all (1024 more)
26350204
Unknown
Disease term Disease name Evidence References Source
Pancreatic adenocarcinoma Pancreatic Ductal Adenocarcinoma PDAC patients with high expression of PSMA6 having a significantly shorter overall survival rate. ClinVar, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Glycosuria Renal Associate 34338422
Uterine Cervical Neoplasms Associate 38203297