FPR2 (formyl peptide receptor 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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2358 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Formyl peptide receptor 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FPR2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ALX, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R |
Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19q13.41 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P25090 | ||||||||||
Protein name | N-formyl peptide receptor 2 (FMLP-related receptor I) (FMLP-R-I) (Formyl peptide receptor-like 1) (HM63) (Lipoxin A4 receptor) (LXA4 receptor) (RFP) | ||||||||||
Protein function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-prote | ||||||||||
PDB | 6LW5 , 6OMM , 7T6S , 7T6U , 7T6V , 7WVV , 7WVW , 7WVX , 7WVY , 8Y62 , 8Y63 | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Detected in lung, bone marrow, neutrophils, spleen and testis. {ECO:0000269|PubMed:15465011, ECO:0000269|PubMed:9151906}. | ||||||||||
Sequence |
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Sequence length | 351 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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