SLC7A8 (solute carrier family 7 member 8)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23428 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 7 member 8 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC7A8 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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LAT2, LPI-PC1 |
Chromosome
Chromosome number
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14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q11.2 |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9UHI5 | ||||||||||
Protein name | Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8) | ||||||||||
Protein function | Associates with SLC3A2 to form a functional heterodimeric complex that translocates small and large neutral amino acids with broad specificity and a stoichiometry of 1:1. Functions as amino acid antiporter mediating the influx of extracellular e | ||||||||||
PDB | 7B00 , 7CMH , 7CMI , 8A6L | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Strongest expression is observed in kidney and moderate expression in placenta and brain, followed by liver, prostate, testis, ovary, lymph node, thymus, spleen, skeletal muscle and heart. Also expressed in fetal liver as well as in th | ||||||||||
Sequence |
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Sequence length | 535 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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