USP24 (ubiquitin specific peptidase 24)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23358 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Ubiquitin specific peptidase 24 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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USP24 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p32.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9UPU5 | |||||||||||||||
| Protein name | Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.4.19.12) (Deubiquitinating enzyme 24) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) | |||||||||||||||
| Protein function | Ubiquitin-specific protease that regulates cell survival in various contexts through modulating the protein stability of some of its substrates including DDB2, MCL1 or TP53. Plays a positive role on ferritinophagy where ferritin is degraded in l | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 2620 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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