Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	2334
Gene name Gene Name - the full gene name approved by the HGNC.	ALF transcription elongation factor 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	AFF2
Synonyms (NCBI Gene) Gene synonyms aliases	FMR2, FMR2P, FRAXE, MRX2, OX19, XLID109
Disease Acronyms (UniProt) Disease acronyms from UniProt database	XLID109
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xq28
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of

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SNP ID	Visualize variation	Clinical significance	Consequence
rs139807832	C>T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant
rs1064796818	A>-	Pathogenic	Frameshift variant, coding sequence variant
rs1557256416	A>T	Pathogenic	Genic upstream transcript variant, stop gained, coding sequence variant
rs1603350606	C>T	Pathogenic	Coding sequence variant, stop gained

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miRTarBase ID	miRNA	Experiments	Reference
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT671754	hsa-miR-933	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT671754	hsa-miR-933	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT645858	hsa-miR-148a-5p	HITS-CLIP	23824327
MIRT645857	hsa-miR-4773	HITS-CLIP	23824327
MIRT645855	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT645856	hsa-miR-488-5p	HITS-CLIP	23824327
MIRT645854	hsa-miR-22-5p	HITS-CLIP	23824327
MIRT645853	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT645852	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT645851	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT619141	hsa-miR-511-3p	HITS-CLIP	23824327
MIRT619140	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT619139	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT619138	hsa-miR-3177-5p	HITS-CLIP	23824327
MIRT619137	hsa-miR-2113	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	20371350
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	20371350
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	20371350
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	20371350
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	20371350
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	20371350
MIRT456079	hsa-miR-185-5p	PAR-CLIP	20371350
MIRT456078	hsa-miR-4306	PAR-CLIP	20371350
MIRT456077	hsa-miR-4644	PAR-CLIP	20371350
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT456075	hsa-miR-8085	PAR-CLIP	20371350
MIRT456074	hsa-miR-3175	PAR-CLIP	20371350
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT456072	hsa-miR-5698	PAR-CLIP	20371350
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT540158	hsa-miR-8485	PAR-CLIP	21572407
MIRT540157	hsa-miR-603	PAR-CLIP	21572407
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	24398324
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	24398324
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	24398324
MIRT488329	hsa-miR-3125	PAR-CLIP	24398324
MIRT488328	hsa-miR-3916	PAR-CLIP	24398324
MIRT488327	hsa-miR-6859-5p	PAR-CLIP	24398324
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	24398324
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	24398324
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	24398324
MIRT488326	hsa-miR-3150b-3p	PAR-CLIP	24398324
MIRT488325	hsa-miR-4784	PAR-CLIP	24398324
MIRT456079	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT456078	hsa-miR-4306	PAR-CLIP	24398324
MIRT456077	hsa-miR-4644	PAR-CLIP	24398324
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT456075	hsa-miR-8085	PAR-CLIP	24398324
MIRT456074	hsa-miR-3175	PAR-CLIP	24398324
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	24398324
MIRT456072	hsa-miR-5698	PAR-CLIP	24398324
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	24398324
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	24398324
MIRT488324	hsa-miR-877-5p	PAR-CLIP	24398324
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT488329	hsa-miR-3125	PAR-CLIP	23592263
MIRT488328	hsa-miR-3916	PAR-CLIP	23592263
MIRT488327	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT488326	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT488325	hsa-miR-4784	PAR-CLIP	23592263
MIRT456079	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT456078	hsa-miR-4306	PAR-CLIP	23592263
MIRT456077	hsa-miR-4644	PAR-CLIP	23592263
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT456075	hsa-miR-8085	PAR-CLIP	23592263
MIRT456074	hsa-miR-3175	PAR-CLIP	23592263
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT456072	hsa-miR-5698	PAR-CLIP	23592263
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT488324	hsa-miR-877-5p	PAR-CLIP	23592263
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	23592263
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	23592263
MIRT456079	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT456078	hsa-miR-4306	PAR-CLIP	23592263
MIRT456077	hsa-miR-4644	PAR-CLIP	23592263
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT456075	hsa-miR-8085	PAR-CLIP	23592263
MIRT456074	hsa-miR-3175	PAR-CLIP	23592263
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT456072	hsa-miR-5698	PAR-CLIP	23592263
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT456079	hsa-miR-185-5p	PAR-CLIP	27292025
MIRT488329	hsa-miR-3125	PAR-CLIP	27292025
MIRT488326	hsa-miR-3150b-3p	PAR-CLIP	27292025
MIRT456074	hsa-miR-3175	PAR-CLIP	27292025
MIRT488328	hsa-miR-3916	PAR-CLIP	27292025
MIRT456078	hsa-miR-4306	PAR-CLIP	27292025
MIRT456077	hsa-miR-4644	PAR-CLIP	27292025
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	27292025
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	27292025
MIRT488325	hsa-miR-4784	PAR-CLIP	27292025
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	27292025
MIRT456072	hsa-miR-5698	PAR-CLIP	27292025
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	27292025
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	27292025
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	27292025
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	27292025
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	27292025
MIRT488327	hsa-miR-6859-5p	PAR-CLIP	27292025
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	27292025
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	27292025
MIRT456075	hsa-miR-8085	PAR-CLIP	27292025
MIRT488324	hsa-miR-877-5p	PAR-CLIP	27292025
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	27418678
MIRT540157	hsa-miR-603	HITS-CLIP	27418678
MIRT540157	hsa-miR-603	HITS-CLIP	27418678
MIRT540158	hsa-miR-8485	HITS-CLIP	27418678
MIRT540158	hsa-miR-8485	HITS-CLIP	27418678
MIRT737973	hsa-miR-1976	HITS-CLIP	28735896
MIRT737974	hsa-miR-4279	HITS-CLIP	28735896
MIRT737970	hsa-miR-4720-3p	HITS-CLIP	28735896
MIRT737971	hsa-miR-4804-3p	HITS-CLIP	28735896
MIRT737969	hsa-miR-548aa	HITS-CLIP	28735896
MIRT737968	hsa-miR-645	HITS-CLIP	28735896
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT671754	hsa-miR-933	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT671754	hsa-miR-933	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT645858	hsa-miR-148a-5p	HITS-CLIP	23824327
MIRT645857	hsa-miR-4773	HITS-CLIP	23824327
MIRT645855	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT645856	hsa-miR-488-5p	HITS-CLIP	23824327
MIRT645854	hsa-miR-22-5p	HITS-CLIP	23824327
MIRT645853	hsa-miR-520a-5p	HITS-CLIP	23824327
MIRT645852	hsa-miR-525-5p	HITS-CLIP	23824327
MIRT645851	hsa-miR-3180-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT633583	hsa-miR-4783-5p	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT619141	hsa-miR-511-3p	HITS-CLIP	23824327
MIRT619140	hsa-miR-3944-5p	HITS-CLIP	23824327
MIRT619139	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT619138	hsa-miR-3177-5p	HITS-CLIP	23824327
MIRT619137	hsa-miR-2113	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT540158	hsa-miR-8485	HITS-CLIP	23824327
MIRT540157	hsa-miR-603	HITS-CLIP	23824327
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	20371350
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	20371350
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	20371350
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	20371350
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	20371350
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	20371350
MIRT456079	hsa-miR-185-5p	PAR-CLIP	20371350
MIRT456078	hsa-miR-4306	PAR-CLIP	20371350
MIRT456077	hsa-miR-4644	PAR-CLIP	20371350
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	20371350
MIRT456075	hsa-miR-8085	PAR-CLIP	20371350
MIRT456074	hsa-miR-3175	PAR-CLIP	20371350
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	20371350
MIRT456072	hsa-miR-5698	PAR-CLIP	20371350
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	20371350
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	20371350
MIRT540158	hsa-miR-8485	PAR-CLIP	21572407
MIRT540157	hsa-miR-603	PAR-CLIP	21572407
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	24398324
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	24398324
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	24398324
MIRT488329	hsa-miR-3125	PAR-CLIP	24398324
MIRT488328	hsa-miR-3916	PAR-CLIP	24398324
MIRT488327	hsa-miR-6859-5p	PAR-CLIP	24398324
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	24398324
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	24398324
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	24398324
MIRT488326	hsa-miR-3150b-3p	PAR-CLIP	24398324
MIRT488325	hsa-miR-4784	PAR-CLIP	24398324
MIRT456079	hsa-miR-185-5p	PAR-CLIP	24398324
MIRT456078	hsa-miR-4306	PAR-CLIP	24398324
MIRT456077	hsa-miR-4644	PAR-CLIP	24398324
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	24398324
MIRT456075	hsa-miR-8085	PAR-CLIP	24398324
MIRT456074	hsa-miR-3175	PAR-CLIP	24398324
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	24398324
MIRT456072	hsa-miR-5698	PAR-CLIP	24398324
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	24398324
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	24398324
MIRT488324	hsa-miR-877-5p	PAR-CLIP	24398324
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT488329	hsa-miR-3125	PAR-CLIP	23592263
MIRT488328	hsa-miR-3916	PAR-CLIP	23592263
MIRT488327	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT488326	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT488325	hsa-miR-4784	PAR-CLIP	23592263
MIRT456079	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT456078	hsa-miR-4306	PAR-CLIP	23592263
MIRT456077	hsa-miR-4644	PAR-CLIP	23592263
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT456075	hsa-miR-8085	PAR-CLIP	23592263
MIRT456074	hsa-miR-3175	PAR-CLIP	23592263
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT456072	hsa-miR-5698	PAR-CLIP	23592263
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT488324	hsa-miR-877-5p	PAR-CLIP	23592263
MIRT456085	hsa-miR-6502-3p	PAR-CLIP	23592263
MIRT456084	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT456083	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT456082	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT456081	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT456080	hsa-miR-4786-5p	PAR-CLIP	23592263
MIRT456079	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT456078	hsa-miR-4306	PAR-CLIP	23592263
MIRT456077	hsa-miR-4644	PAR-CLIP	23592263
MIRT456076	hsa-miR-6731-5p	PAR-CLIP	23592263
MIRT456075	hsa-miR-8085	PAR-CLIP	23592263
MIRT456074	hsa-miR-3175	PAR-CLIP	23592263
MIRT456073	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT456072	hsa-miR-5698	PAR-CLIP	23592263
MIRT456071	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT456070	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT770989	hsa-miR-122	CLIP-seq
MIRT770990	hsa-miR-1273d	CLIP-seq
MIRT770991	hsa-miR-1290	CLIP-seq
MIRT770992	hsa-miR-1294	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT770994	hsa-miR-197	CLIP-seq
MIRT770995	hsa-miR-200b	CLIP-seq
MIRT770996	hsa-miR-200c	CLIP-seq
MIRT770997	hsa-miR-205	CLIP-seq
MIRT770998	hsa-miR-2115	CLIP-seq
MIRT770999	hsa-miR-3126-5p	CLIP-seq
MIRT771000	hsa-miR-3148	CLIP-seq
MIRT771001	hsa-miR-3185	CLIP-seq
MIRT771002	hsa-miR-3198	CLIP-seq
MIRT771003	hsa-miR-3646	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT771004	hsa-miR-374c	CLIP-seq
MIRT771005	hsa-miR-412	CLIP-seq
MIRT771006	hsa-miR-429	CLIP-seq
MIRT771007	hsa-miR-4309	CLIP-seq
MIRT771008	hsa-miR-4316	CLIP-seq
MIRT771009	hsa-miR-4419a	CLIP-seq
MIRT771010	hsa-miR-4428	CLIP-seq
MIRT771011	hsa-miR-4510	CLIP-seq
MIRT771012	hsa-miR-4653-3p	CLIP-seq
MIRT771013	hsa-miR-4685-5p	CLIP-seq
MIRT771014	hsa-miR-4693-5p	CLIP-seq
MIRT771015	hsa-miR-4778-5p	CLIP-seq
MIRT771016	hsa-miR-515-5p	CLIP-seq
MIRT771017	hsa-miR-539	CLIP-seq
MIRT771018	hsa-miR-610	CLIP-seq
MIRT771019	hsa-miR-655	CLIP-seq
MIRT771020	hsa-miR-665	CLIP-seq
MIRT771021	hsa-miR-888	CLIP-seq
MIRT771022	hsa-miR-935	CLIP-seq
MIRT771023	hsa-miR-1276	CLIP-seq
MIRT771024	hsa-miR-3662	CLIP-seq
MIRT771025	hsa-miR-3682-3p	CLIP-seq
MIRT771026	hsa-miR-4311	CLIP-seq
MIRT771027	hsa-miR-583	CLIP-seq
MIRT771028	hsa-miR-103a	CLIP-seq
MIRT771029	hsa-miR-107	CLIP-seq
MIRT771030	hsa-miR-1184	CLIP-seq
MIRT771031	hsa-miR-1200	CLIP-seq
MIRT771032	hsa-miR-15a	CLIP-seq
MIRT771033	hsa-miR-15b	CLIP-seq
MIRT771034	hsa-miR-16	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT771035	hsa-miR-195	CLIP-seq
MIRT771036	hsa-miR-203	CLIP-seq
MIRT771037	hsa-miR-217	CLIP-seq
MIRT771038	hsa-miR-28-5p	CLIP-seq
MIRT771039	hsa-miR-3139	CLIP-seq
MIRT771040	hsa-miR-3607-3p	CLIP-seq
MIRT771041	hsa-miR-3667-5p	CLIP-seq
MIRT771042	hsa-miR-3690	CLIP-seq
MIRT771043	hsa-miR-380	CLIP-seq
MIRT771044	hsa-miR-3919	CLIP-seq
MIRT771045	hsa-miR-3925-5p	CLIP-seq
MIRT771046	hsa-miR-409-3p	CLIP-seq
MIRT771047	hsa-miR-424	CLIP-seq
MIRT771048	hsa-miR-4254	CLIP-seq
MIRT771049	hsa-miR-4307	CLIP-seq
MIRT771050	hsa-miR-4326	CLIP-seq
MIRT771051	hsa-miR-4418	CLIP-seq
MIRT771052	hsa-miR-4421	CLIP-seq
MIRT771053	hsa-miR-4495	CLIP-seq
MIRT771054	hsa-miR-4514	CLIP-seq
MIRT771055	hsa-miR-4524	CLIP-seq
MIRT771056	hsa-miR-4645-5p	CLIP-seq
MIRT771057	hsa-miR-4673	CLIP-seq
MIRT771058	hsa-miR-4686	CLIP-seq
MIRT771059	hsa-miR-4687-3p	CLIP-seq
MIRT771060	hsa-miR-4692	CLIP-seq
MIRT771061	hsa-miR-4755-3p	CLIP-seq
MIRT771062	hsa-miR-4793-5p	CLIP-seq
MIRT771063	hsa-miR-497	CLIP-seq
MIRT771064	hsa-miR-503	CLIP-seq
MIRT771065	hsa-miR-507	CLIP-seq
MIRT771066	hsa-miR-509-3-5p	CLIP-seq
MIRT771067	hsa-miR-509-5p	CLIP-seq
MIRT771068	hsa-miR-518a-5p	CLIP-seq
MIRT771069	hsa-miR-527	CLIP-seq
MIRT771070	hsa-miR-548n	CLIP-seq
MIRT771071	hsa-miR-548t	CLIP-seq
MIRT771072	hsa-miR-557	CLIP-seq
MIRT771073	hsa-miR-589	CLIP-seq
MIRT771074	hsa-miR-646	CLIP-seq
MIRT771075	hsa-miR-708	CLIP-seq
MIRT771076	hsa-miR-940	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT1545179	hsa-miR-877	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT770990	hsa-miR-1273d	CLIP-seq
MIRT1927454	hsa-miR-1299	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT1927455	hsa-miR-3120-3p	CLIP-seq
MIRT1927456	hsa-miR-3167	CLIP-seq
MIRT1927457	hsa-miR-342-5p	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT771046	hsa-miR-409-3p	CLIP-seq
MIRT1927458	hsa-miR-4422	CLIP-seq
MIRT771053	hsa-miR-4495	CLIP-seq
MIRT771054	hsa-miR-4514	CLIP-seq
MIRT771056	hsa-miR-4645-5p	CLIP-seq
MIRT1927459	hsa-miR-4654	CLIP-seq
MIRT1927460	hsa-miR-4664-5p	CLIP-seq
MIRT771057	hsa-miR-4673	CLIP-seq
MIRT771060	hsa-miR-4692	CLIP-seq
MIRT1927461	hsa-miR-4704-3p	CLIP-seq
MIRT1927462	hsa-miR-4712-5p	CLIP-seq
MIRT771061	hsa-miR-4755-3p	CLIP-seq
MIRT1927463	hsa-miR-4769-5p	CLIP-seq
MIRT1927464	hsa-miR-4782-5p	CLIP-seq
MIRT1927465	hsa-miR-498	CLIP-seq
MIRT1927466	hsa-miR-516b	CLIP-seq
MIRT1927467	hsa-miR-562	CLIP-seq
MIRT1927468	hsa-miR-770-5p	CLIP-seq
MIRT1927469	hsa-miR-876-5p	CLIP-seq
MIRT2168201	hsa-miR-125a-3p	CLIP-seq
MIRT2168202	hsa-miR-1286	CLIP-seq
MIRT2168203	hsa-miR-133a	CLIP-seq
MIRT2168204	hsa-miR-133b	CLIP-seq
MIRT2168205	hsa-miR-141	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT2168206	hsa-miR-200a	CLIP-seq
MIRT2168207	hsa-miR-2964a-3p	CLIP-seq
MIRT2168208	hsa-miR-3124-3p	CLIP-seq
MIRT771002	hsa-miR-3198	CLIP-seq
MIRT2168209	hsa-miR-330-3p	CLIP-seq
MIRT2168210	hsa-miR-3622a-3p	CLIP-seq
MIRT2168211	hsa-miR-3622b-3p	CLIP-seq
MIRT2168212	hsa-miR-3657	CLIP-seq
MIRT2168213	hsa-miR-3688-3p	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT771007	hsa-miR-4309	CLIP-seq
MIRT2168214	hsa-miR-4436a	CLIP-seq
MIRT2168215	hsa-miR-4438	CLIP-seq
MIRT2168216	hsa-miR-4689	CLIP-seq
MIRT2168217	hsa-miR-4722-5p	CLIP-seq
MIRT2168218	hsa-miR-4762-3p	CLIP-seq
MIRT2168219	hsa-miR-4765	CLIP-seq
MIRT2168220	hsa-miR-490-5p	CLIP-seq
MIRT2168221	hsa-miR-5095	CLIP-seq
MIRT771068	hsa-miR-518a-5p	CLIP-seq
MIRT771069	hsa-miR-527	CLIP-seq
MIRT2168222	hsa-miR-579	CLIP-seq
MIRT771073	hsa-miR-589	CLIP-seq
MIRT2168223	hsa-miR-627	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT2443289	hsa-miR-1226	CLIP-seq
MIRT2443290	hsa-miR-1293	CLIP-seq
MIRT770993	hsa-miR-185	CLIP-seq
MIRT2443291	hsa-miR-186	CLIP-seq
MIRT2443292	hsa-miR-3157-5p	CLIP-seq
MIRT2443293	hsa-miR-4267	CLIP-seq
MIRT2443294	hsa-miR-4483	CLIP-seq
MIRT2443295	hsa-miR-4659a-3p	CLIP-seq
MIRT2443296	hsa-miR-4659b-3p	CLIP-seq
MIRT2443297	hsa-miR-4691-3p	CLIP-seq
MIRT1545179	hsa-miR-877	CLIP-seq
MIRT2470910	hsa-miR-1205	CLIP-seq
MIRT2470911	hsa-miR-1236	CLIP-seq
MIRT771023	hsa-miR-1276	CLIP-seq
MIRT2168205	hsa-miR-141	CLIP-seq
MIRT2470912	hsa-miR-1909	CLIP-seq
MIRT2168206	hsa-miR-200a	CLIP-seq
MIRT2470913	hsa-miR-216b	CLIP-seq
MIRT2443292	hsa-miR-3157-5p	CLIP-seq
MIRT771003	hsa-miR-3646	CLIP-seq
MIRT771024	hsa-miR-3662	CLIP-seq
MIRT737972	hsa-miR-370	CLIP-seq
MIRT2470914	hsa-miR-421	CLIP-seq
MIRT2470915	hsa-miR-4272	CLIP-seq
MIRT771026	hsa-miR-4311	CLIP-seq
MIRT2470916	hsa-miR-4452	CLIP-seq
MIRT2443297	hsa-miR-4691-3p	CLIP-seq
MIRT2470917	hsa-miR-4709-5p	CLIP-seq
MIRT2470918	hsa-miR-4744	CLIP-seq
MIRT2470919	hsa-miR-4778-3p	CLIP-seq
MIRT771027	hsa-miR-583	CLIP-seq

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002151	Function	G-quadruplex RNA binding	IBA	21873635
GO:0002151	Function	G-quadruplex RNA binding	ISS
GO:0006397	Process	MRNA processing	IEA
GO:0007420	Process	Brain development	TAS	8673086
GO:0007611	Process	Learning or memory	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0010468	Process	Regulation of gene expression	IBA	21873635
GO:0010468	Process	Regulation of gene expression	IMP	23562910
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0016607	Component	Nuclear speck	IBA	21873635
GO:0016607	Component	Nuclear speck	IDA	19136466
GO:0032783	Component	Super elongation complex	IBA	21873635
GO:0035063	Process	Nuclear speck organization	IMP	23562910
GO:0043484	Process	Regulation of RNA splicing	IBA	21873635
GO:0043484	Process	Regulation of RNA splicing	IMP	19136466

MIM	HGNC	e!Ensembl
300806	3776	ENSG00000155966

Protein

UniProt ID

P51816

Protein name

AF4/FMR2 family member 2 (Protein FMR-2) (FMR2P) (Protein Ox19)

Protein function

RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF05110	AF-4	18 → 535		Family
PF18875	AF4_int	801 → 815	AF4 interaction motif	Motif
PF18876	AF-4_C	1054 → 1311	AF-4 proto-oncoprotein C-terminal region	Family

Tissue specificity

TISSUE SPECIFICITY: Brain (most abundant in hippocampus and amygdala), placenta and lung.

Sequence

MDLFDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEDDLFSSGFDLFGEPYKVAEY
TNKGDALANRVQNTLGNYDEMKNLLTNHSNQNHLVGIPKNSVPQNPNNKNEPSFFPEQKN
RIIPPHQDNTHPSAPMPPPSVVILNSTLIHSNRKSKPEWSRDSHNPSTVLASQASGQPNK
MQTLTQDQSQAKLEDFFVYPAEQPQIGEVEESNPSAKEDSNPNSSGEDAFKEIFQSNSPE
ESEFAVQAPGSPLVASSLLAPSSGLSVQNFPPGLYCKTSMGQQKPTAYVRPMDGQDQAPD
ISPTLKPSIEFENSFGNLSFGTLLDGKPSAASSKTKLPKFTILQTSEVSLPSDPSCVEEI
LREMTHSWPTPLTSMHTAGHSEQSTFSIPGQESQHLTPGFTLQKWNDPTTRASTKSVSFK
SMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQPPPAVQA
SGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQ
NKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNASQVPAEPKERPLLSLIREKARPRP
TQKIPETKALKHKLSTTSETVSQRTIGKKQPKKVEKNTSTDEFTWPKPNITSSTPKEKES
VELHDPPRGRNKATAHKPAPRKEPRPNIPLAPEKKKYRGPGKIVPKSREFIETDSSTSDS
NTDQEETLQIKVLPPCIISGGNTAKSKEICGASLTLSTLMSSSGSNNNLSISNEEPTFSP
IPVMQTEILSPLRDHENLKNLWVKIDLDLLSRVPGHSSLHAAPAKPDHKETATKPKRQTA
VTAVEKPAPKGKRKHKPIEVAEKIPEKKQRLEEATTICLLPPCISPAPPHKPPNTRENNS
SRRANRRKEEKLFPPPLSPLPEDPPRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGK
FCATFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATATATATTTTTT
TTISTITSTITTGLMDSSHLEMTSWAALPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAK
KLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRL
KNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIP
SPWVSNGKNTPSPVSLNNVSPINAMGNCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHW
DMADKLTRENKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL

Sequence length

1311

Interactions

View interactions

Show/Hide Causal Diseases (4)

Disease term	Disease name	dbSNP ID	References
Causal
Autism	Autistic behavior	rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699 View all (8 more)
Fragile x syndrome	Fragile X Syndrome, FRAXA Syndrome, FRAXE Syndrome, FRAXE intellectual disability	rs121434622, rs1569545562, rs1557176576, rs193922937, rs1569545382, rs193922936	8334699, 8673086, 7783162, 9341861, 14526173, 7536393, 9032643, 8023854, 23562910, 21739600, 9475603
Macrocephaly	Macrocephaly	rs786204854, rs764333096, rs1557739557
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315 View all (1024 more)

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Specific learning disorder	Specific learning disability	ClinVar
Neuroticism	Neuroticism	GWAS

Show/Hide Text Mining Associations (31)

Disease Name	Relationship Type	References
Associations from Text Mining
Arthritis Rheumatoid	Stimulate	33653372
Autism Spectrum Disorder	Associate	22773736, 23849776, 30392976, 32393163
Autistic Disorder	Associate	10424820, 26612855
Carcinoma Adenosquamous	Associate	36849671
Carcinoma Squamous Cell	Associate	35773081
Central Nervous System Neoplasms	Associate	35115049
Colorectal Neoplasms	Associate	37381158
Developmental Disabilities	Associate	10424820
Endometriosis	Associate	35429182
Epilepsy	Associate	10424820
Eye Neoplasms	Associate	32393163
Fragile X Syndrome	Associate	10424820, 23849776, 34111553, 7902673
Fragile X Syndrome	Inhibit	22773736
Fragile X Syndrome	Stimulate	30264515
Glioblastoma	Associate	25351872
Head and Neck Neoplasms	Associate	35773081
Hemophilia B	Associate	30264515
Inflammation	Associate	33653372
Intellectual Disability	Associate	10424820, 22773736, 23914978, 30264515, 35326495
Joint Instability	Associate	10424820
Mucopolysaccharidosis II	Associate	35916809
Multiple Myeloma	Associate	31948430
Neoplasms	Associate	35429182, 35753349, 35773081, 37118352
Neoplasms Neuroepithelial	Associate	35115049
Neuroblastoma	Associate	32707690
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	9233580
Rectal Neoplasms	Associate	37381158
Sarcoma	Associate	35429182
Thoracic Neoplasms	Associate	35773081
Thymoma	Associate	33704915
Uterine Cervical Neoplasms	Associate	37628839

AFF2 (ALF transcription elongation factor 2)